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Central Pulse Pressure

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https://www.readbyqxmd.com/read/28914847/-efficiency-of-triple-antihypertensive-therapy-in-patients-with-uncontrolled-hypertension-and-depressive-disorders
#1
V V Skibitsky, A V Fendrikova, A V Skibitsky
AIM: To evaluate the efficiency of triple antihypertensive therapy in patients with uncontrolled hypertension and depressive disorders (DD). MATERIAL AND METHODS: 153 patients with uncontrolled hypertension were examined, of whom 82 patients were diagnosed with mild and moderate DD. A combination of perindopril 10 mg/day, indapamide SR 1.5 mg/day, and amlodipine at an initial dose of 5 mg/day was given to patients with hypertension and DD. After 4 weeks of treatment, if target blood pressure (BP) levels could not be achieved, the dose of amlodipine was increased up to 10 mg/day...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28914629/association-between-ambulatory-blood-pressure-values-and-central-aortic-pressure-in-a-large-population-of-normotensive-and-hypertensive-patients
#2
Ana Rouxinol-Dias, Sara Araújo, José A Silva, Loide Barbosa, Jorge Polónia
OBJECTIVE: Our aim was to examine the association of ambulatory blood pressure monitoring (ABPM) and central blood pressure (CBP) data in a large set of normotensive and hypertensive patients and its relation with pulse wave velocity (PWV). PATIENTS AND METHODS: This cross-sectional study was carried out in a single centre and included 2864 individuals who carried out an ABPM, measurement of CBP from the aortic waveform (SphygmoCor) and carotid-femoral PWV (Complior)...
September 13, 2017: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/28911022/hypertensive-cardiovascular-risk-pulsatile-hemodynamics-gender-and-therapeutic-implications
#3
Michel E Safar, Harold Smulyan
PURPOSE: In recent years, the predictive value of 2 pulsatile parameters has been extensively studied in hypertension: aortic stiffness and pulse pressure (PP) amplification. Aortic stiffness is an index of aortic rigidity and PP-amplification is the ratio between central and brachial PP, an indirect evaluation of wave reflections. Both are safe, independent, noninvasive predictors of overall and cardiovascular risk. Our purpose is to determine the validity of these parameters in 2 different circumstances: gender and therapeutic implications...
October 1, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28893900/labetalol-versus-nifedipine-as-antihypertensive-treatment-for-chronic-hypertension-in-pregnancy-a-randomized-controlled-trial
#4
Louise M Webster, Jenny E Myers, Catherine Nelson-Piercy, Kate Harding, J Kennedy Cruickshank, Ingrid Watt-Coote, Asma Khalil, Cornelia Wiesender, Paul T Seed, Lucy C Chappell
Data from randomized controlled trials to guide antihypertensive agent choice for chronic hypertension in pregnancy are limited; this study aimed to compare labetalol and nifedipine, additionally assessing the impact of ethnicity on treatment efficacy. Pregnant women with chronic hypertension (12(+0)-27(+6) weeks' gestation) were enrolled at 4 UK centers (August 2014 to October 2015). Open-label first-line antihypertensive treatment was randomly assigned: labetalol- (200-1800 mg/d) or nifedipine-modified release (20-80 mg/d)...
September 11, 2017: Hypertension
https://www.readbyqxmd.com/read/28893431/pulse-pressure-amplification-and-its-relationship-with-age-in-young-apparently-healthy-black-and-white-adults-the-african-predict-study
#5
Yolandi Breet, Hugo W Huisman, Ruan Kruger, Johannes M van Rooyen, Lebo F Gafane-Matemane, Lisa J Ware, Aletta E Schutte
BACKGROUND: Pulse pressure amplification (PPA), i.e. the amplification from central arteries to the periphery, is inversely related to arterial stiffness, organ damage and mortality. It is known that arterial stiffness is higher in black than white populations, but it is unclear if this is due to early vascular aging. We therefore investigated whether PPA declines earlier in young normotensive black South Africans, when compared to their white counterparts. METHODS: We included 875 black and white men and women from the African-PREDICT study (55% black, 41% men), aged 20-30years, with no prior diagnosis of chronic disease, screened for normotensive clinic blood pressure (BP)...
September 5, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28887501/voluntary-liquorice-ingestion-increases-blood-pressure-via-increased-volume-load-elevated-peripheral-arterial-resistance-and-decreased-aortic-compliance
#6
Elina J Hautaniemi, Anna M Tahvanainen, Jenni K Koskela, Antti J Tikkakoski, Mika Kähönen, Marko Uitto, Kalle Sipilä, Onni Niemelä, Jukka Mustonen, Ilkka H Pörsti
We investigated the haemodynamic effects of two-week liquorice exposure (glycyrrhizin dose 290-370 mg/day) in 22 healthy volunteers during orthostatic challenge. Haemodynamics were recorded during passive 10-minute head-up tilt using radial pulse wave analysis, whole-body impedance cardiography, and spectral analysis of heart rate variability. Thirty age-matched healthy subjects served as controls. Liquorice ingestion elevated radial systolic (p < 0.001) and diastolic (p = 0.018) blood pressure and systemic vascular resistance (p = 0...
September 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28886599/associations-between-greenness-impervious-surface-area-and-nighttime-lights-on-biomarkers-of-vascular-aging-in-chennai-india
#7
Kevin J Lane, Eleanor C Stokes, Karen C Seto, Sadagopan Thanikachalam, Mohan Thanikachalam, Michelle L Bell
BACKGROUND: India is undergoing rapid urbanization with simultaneous increases in the prevalence of cardiovascular disease (CVD). As urban areas become home to an increasing share of the world's population, it is important to understand relationships between the built environment and progression towards CVD. OBJECTIVE: We assessed associations between multiple measures of the built environment and biomarkers of early vascular aging (EVA) in the Population Study of Urban, Rural and Semiurban Regions for the Detection of Endovascular Disease and Prevalence of Risk Factors and Holistic Intervention Study (PURSE-HIS) in Chennai, India...
August 2, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28882449/contribution-of-backward-and-forward-wave-pressures-to-age-related-increases-in-aortic-pressure-in-a-community-sample-not-receiving-antihypertensive-therapy
#8
Bryan Hodson, Gavin R Norton, Imraan Ballim, Pinhas Sareli, Angela J Woodiwiss
Reports on the contribution of aortic forward (Pf) and backward (Pb) wave pressures to age-related increases in central aortic pulse pressure (PPc) have been confounded by the use of participants receiving antihypertensive therapy. We assessed the relative contribution of Pf and Pb to age-related increases in PPc (radial applanation tonometry and SphygmoCor software using an assumed triangular wave for wave separation analysis) in 892 community participants not receiving antihypertensive therapy. We validated our results using aortic flow waves (echocardiography) for wave separation analysis in 254 of these participants...
August 24, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28879040/comparison-of-effects-between-calcium-channel-blocker-and-diuretics-in-combination-with-angiotensin-ii-receptor-blocker-on-24-h-central-blood-pressure-and-vascular-hemodynamic-parameters-in-hypertensive-patients-study-design-for-a-multicenter-double-blinded
#9
Gyu Chul Oh, Hae-Young Lee, Wook Jin Chung, Ho-Joong Youn, Eun-Joo Cho, Ki-Chul Sung, Shung Chull Chae, Byung-Su Yoo, Chang Gyu Park, Soon Jun Hong, Young Kwon Kim, Taek-Jong Hong, Dong-Ju Choi, Min Su Hyun, Jong Won Ha, Young Jo Kim, Youngkeun Ahn, Myeong Chan Cho, Soon-Gil Kim, Jinho Shin, Sungha Park, Il-Suk Sohn, Chong-Jin Kim
BACKGROUND: Hypertension is a risk factor for coronary heart disease and stroke, and is one of the leading causes of death. Although over a billion people are affected worldwide, only half of them receive adequate treatment. Current guidelines on antihypertensive treatment recommend combination therapy for patients not responding to monotherapy, but as the number of pills increase, patient compliance tends to decrease. As a result, fixed-dose combination drugs with different antihypertensive agents have been developed and widely used in recent years...
2017: Clinical Hypertension
https://www.readbyqxmd.com/read/28868990/the-effects-of-whole-body-vibration-on-pulse-wave-velocity-in-men-with-chronic-spinal-cord-injury
#10
Julia O Totosy de Zepetnek, Masae Miyatani, Maggie Szeto, Lora M Giangregorio, B Catharine Craven
Objective A pilot study to evaluate the therapeutic potential of 40 weeks of passive standing with whole body vibration (PS-WBV) on central and peripheral arterial stiffness among men with chronic spinal cord injury (SCI). Methods Consenting participants were pre-screened to ensure safe participation. Fifteen individuals with chronic SCI were enrolled to participate in PS-WBV sessions three times per week for 40 weeks on a modified WAVE platform custom-fitted with an EASYStand 5000. Knee angle was set at 160°, and vibration parameters were 45Hz frequency and 0...
September 4, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28868168/validity-of-pulse-pressure-variation-ppv-compared-with-stroke-volume-variation-svv-in-predicting-fluid-responsiveness
#11
Abhishek Rathore, Shalendra Singh, Ritesh Lamsal, Priya Taank, Debashish Paul
OBJECTIVE: Static monitors for assessing the fluid status during major surgeries and in critically ill patients have been gradually replaced by more accurate dynamic monitors in modern-day anaesthesia practice. Pulse pressure variation (PPV) and systolic pressure variation (SPV) are the two commonly used dynamic indices for assessing fluid responsiveness. METHODS: In this prospective observational study, 50 patients undergoing major surgeries were monitored for PPV and SPV: after the induction of anaesthesia and after the administration of 500 mL of isotonic crystalloid bolus...
August 2017: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/28864036/aerobic-training-effect-on-arterial-stiffness-in-metabolic-syndrome
#12
Ieva Slivovskaja, Ligita Ryliskyte, Pranas Serpytis, Rokas Navickas, Jolita Badarienė, Jelena Celutkiene, Roma Puronaite, Kristina Ryliskiene, Alma Cypiene, Egidija Rinkuniene, Vaida Sileikiene, Birute Petrauskiene, Alvydas Juocevicius, Aleksandras Laucevicius
BACKGROUND: Metabolic syndrome, physical inactivity and central obesity contribute to early vascular aging, which leads to increased risk of cardiovascular disease. The study aimed to assess the effect of heart rate (HR) targeted aerobic exercise training on the indices of early vascular aging, in particular, arterial stiffness, and on anthropometric and clinical profile of metabolic syndrome subjects. METHODS: 126 metabolic syndrome subjects were randomly selected...
August 29, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28862955/sex-differences-in-associations-of-arterial-compliance-with-coronary-artery-plaque-and-calcification-burden
#13
Thais Coutinho, Yeung Yam, Benjamin J W Chow, Girish Dwivedi, João Inácio
BACKGROUND: Coronary artery disease is a leading killer of women. Arterial stiffness predicts myocardial infarction, and postmenopausal women have lower arterial compliance (AC) than men. We hypothesized that lower AC would be associated with greater burden of coronary artery plaque and calcification, and that these associations would be stronger in women than men. METHODS AND RESULTS: We evaluated 3639 consecutive adults without coronary artery disease history who had coronary computed tomography between 2006 and 2014...
August 19, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28861004/the-temporal-relationship-between-arterial-stiffening-and-blood-pressure-is-modified-by-methotrexate-treatment-in-patients-with-rheumatoid-arthritis
#14
Richard J Woodman, Leena R Baghdadi, Michael E Shanahan, Arduino A Mangoni
Background: The temporal relationship between arterial stiffness and blood pressure (BP) may vary depending on age and other clinical and demographic factors. Since both BP and arterial stiffness are also affected by inflammatory processes, we examined the temporal arterial stiffness-BP relationship in patients with rheumatoid arthritis (RA) treated with either methotrexate (MTX), an anti-rheumatic agent shown to reduce cardiovascular risk in meta-analyses, or other disease-modifying anti-rheumatic drugs (DMARDs)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28857336/aerobic-exercise-training-does-not-alter-vascular-structure-and-function-in-chronic-obstructive-pulmonary-disease
#15
Jinelle C Gelinas, Nia C Lewis, Megan I Harper, Bernie Melzer, Gloria Agar, J Douglass Rolf, Neil D Eves
Chronic obstructive pulmonary disease (COPD) has been associated with endothelial dysfunction and arterial stiffening, which are predictive of future cardiovascular events. While aerobic exercise improves vascular function in healthy individuals and those with chronic disease, it is unknown if aerobic exercise can positively modify the vasculature in COPD. We examined the effects of 8-weeks of periodised aerobic training on vascular structure and function and inflammation in 24 patients with COPD (age = 69 ± 7 yrs, FEV1 %pred = 68 ± 19%) and 20 matched controls (age = 64 ± 5 yrs, FEV1 %pred = 113 ± 16%) for comparison...
August 31, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28853610/white-matter-hyperintensities-in-migraine-clinical-significance-and-central-pulsatile-hemodynamic-correlates
#16
Chun-Yu Cheng, Hao-Min Cheng, Shih-Pin Chen, Chih-Ping Chung, Yung-Yang Lin, Han-Hwa Hu, Chen-Huan Chen, Shuu-Jiun Wang
Background The role of central pulsatile hemodynamics in the pathogenesis of white matter hyperintensities in migraine patients has not been clarified. Methods Sixty patients with migraine (20-50 years old; women, 68%) without overt vascular risk factors and 30 demographically-matched healthy controls were recruited prospectively. Cerebral white matter hyperintensities volume was determined by T1-weighted magnetic resonance imaging with CUBE-fluid-attenuated-inversion-recovery sequences. Central systolic blood pressure, carotid-femoral pulse wave velocity, and carotid augmentation index were measured by applanation tonometry...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28845403/the-effect-of-comprehensive-care-on-the-patients-received-minimally-invasive-percutaneous-nephrolithotomy
#17
Xue-Li Wei, Mei-Fang Xue, Zhao-Xia Qin, Xing-Yun Bai, Fang-Fang Dong, Jin-Jin Zhang, Ning Lv, Hui Chen, Jia Zhang
BACKGROUND: We analyzed the effect of comprehensive care on the patients who received minimally invasive percutaneous nephrolithotomy (MPCNL). METHODS: Patients hospitalized from 2013-2014 in Zhumadian Central Hospital (n=124) were enrolled and divided into two groups on random basis. The control group was treated with routine nursing model while the observation group was given comprehensive care additionally. The surgery time, degree of comfort, complications and successful cases, hospitalization time, sleep quality, nursing satisfaction and changes of systolic pressure, pulse and respiratory at different time were observed and analyzed...
July 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28837291/-prehospital-misconceptions
#18
Eduardo Alcouce, Vincent Darioli, Pierre-Nicolas Carron, Mathieu Pasquier
We confronted some of the most prevalent prehospital misconceptions with the available literature. We found that: the diminution of a retrosternal pain following nitrate administration is not predictive of a cardiac origin of the pain ; survival of traumatic cardiac arrest may not be as bad as usually believed ; peripheral venous administration of vasopressors through proximal catheters during short times may be considered as a safe temporary alternative to central venous access ; using the pulse palpation usually lead to an under-estimation of the systolic blood pressure ; applying a pelvic belt at the level of the iliac crests doesn't aggravate an open-book fracture; there is no 90 mmHg threshold values below which mortality increases in traumatic brain injuries...
August 9, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28835849/the-impact-on-central-blood-pressure-and-arterial-stiffness-post-renal-denervation-in-patients-with-stage-3-and-4-chronic-kidney-disease-the-prairie-renal-denervation-study
#19
Bhanu Prasad, Jennifer Rose St Onge, Michelle C E McCarron, Kunal Goyal, Payam Dehghani
BACKGROUND: Central aortic blood pressures and arterial stiffness are better indicators of cardiovascular outcomes than brachial blood pressures. However, their response to renal denervation (RDN) in patients with stage 3 and stage 4 chronic kidney disease (CKD) has not yet been examined. OBJECTIVE: To evaluate the impact of RDN on central blood pressures, brachial (office and ambulatory) blood pressures, arterial stiffness, glomerular filtration rate (GFR), 24-hour urine protein, and selective cardiac parameters observed on echocardiograms...
2017: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/28830669/central-systolic-blood-pressure-and-aortic-stiffness-response-to-dietary-sodium-in-young-and-middle-aged-adults
#20
Bryce J Muth, Michael S Brian, Julio A Chirinos, Shannon L Lennon, William B Farquhar, David G Edwards
High dietary sodium intake can lead to hypertension and increased incidence of cardiovascular disease. We sought to determine the effect of short-term dietary sodium loading on central blood pressure and arterial stiffness in young (YG; 22-40 years) and middle-aged (MA; 41-60 years) normotensive adults. YG (n = 49; age: 27 ± 1 years) and MA (n = 36; age: 52 ± 1 years) subjects were randomized, in a cross-over design, to 7 days of low-sodium (LS; 20 mmol/d) or high-sodium (HS; 300 mmol/d) diet...
July 28, 2017: Journal of the American Society of Hypertension: JASH
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