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Central Pulse Pressure

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https://www.readbyqxmd.com/read/27905876/age-and-sex-specific-associations-of-anthropometric-measures-of-adiposity-with-blood-pressure-and-hypertension-in-india-a-cross-sectional-study
#1
Kevin Y Taing, Michael E Farkouh, Rahim Moineddin, Jack V Tu, Prabhat Jha
BACKGROUND: A determinant of blood pressure is adiposity; however, there are uncertainties surrounding whether general or central adiposity is the more important determinant of blood pressure. Further, inconsistent results exist for the relationships of anthropometric measures with blood pressure and hypertension, and whether these relationships differ substantially by age and sex is unclear. We aimed to elucidate the associations of anthropometric measures of general and central adiposity with blood pressure and hypertension, and determine the effect of age and sex on these relationships...
December 1, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27900498/central-hemodynamics-and-arterial-stiffness-in-idiopathic-and-multiple-system-atrophy
#2
Klaas Franzen, Sabine Fliegen, Jelena Koester, Rafael Campos Martin, Günther Deuschl, Michael Reppel, Kai Mortensen, Susanne A Schneider
Blood pressure is commonly abnormal in parkinsonian disorders, but central hemodynamics and arterial stiffness, well-established predictors of total cardiovascular risk, have rarely been studied in these disorders. 32 patients [27 with idiopathic Parkinson's disease (iPD); 5 with multiple system atrophy (MSA)] and 15 controls matched for cardiac risk factors underwent 24 h-ambulatory blood pressure recordings using an I.E.M. device (Mobil-O-Graph™), measuring peripheral pressure and calculating central pressures and arterial stiffness...
November 29, 2016: Journal of Neurology
https://www.readbyqxmd.com/read/27899177/a-personalized-model-based-central-aortic-pressure-estimation-method
#3
Sheng Jiang, Zhi-Qiang Zhang, Fang Wang, Jian-Kang Wu
Central Aortic Pressure (CAP) can be used to predict cardiovascular structural damage and cardiovascular events, and the development of simple, well-validated and non-invasive methods for CAP waveforms estimation is critical to facilitate the routine clinical applications of CAP. Existing widely applied methods, such as generalized transfer function (GTF-CAP) method and N-Point Moving Average (NPMA-CAP) method, are based on clinical practices, and lack a mathematical foundation. Those methods also have inherent drawback that there is no personalisation, and missing individual aortic characteristics...
November 22, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27891374/effect-of-enhanced-external-counter-pulsation-treatment-on-aortic-blood-pressure-arterial-stiffness-and-ejection-fraction-in-patients-with-coronary-artery-disease
#4
Ramasamy Subramanian, Sushma Nayar, Chokkalingam Meyyappan, N Ganesh, Arumugam Chandrakasu, Pradeep G Nayar
INTRODUCTION: Enhanced External Counter Pulsation (EECP) is a non-invasive treatment option for patients with Coronary Artery Disease (CAD). The treatment has shown to augment diastolic pressure and reduce Left Ventricular (LV) after-load by reducing systemic vascular resistance. The effect of EECP in standard brachial blood pressure and central haemodynamic parameters are not known. AIM: We hypothesized that EECP may have differential effect in CAD patients with low systolic blood pressure when compared to normal systolic pressure and the mechanism underlying this differential effect may be due to improvement in LV function...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27885499/the-effects-of-alpha-1-adrenoceptor-blockade-and-angiotensin-converting-enzyme-inhibition-on-central-and-brachial-blood-pressure-and-vascular-reactivity-the-doxazosin-ramipril-study
#5
Andreas Jekell, Majid Kalani, Thomas Kahan
We aimed to study whether inhibition of the renin-angiotensin-aldosterone system has effects on vascular structure and function beyond the effects on blood pressure reduction alone. Patients with mild-to-moderate hypertension (n = 61, age 54 ± 12 years, 34% women) received the angiotensin converting enzyme inhibitor ramipril 10 mg or the alpha 1-adrenoceptor blocker doxazosin 8 mg double-blind for 12 weeks. Aortic blood pressure, pulse wave velocity, and augmentation index were assessed by applanation tonometry...
November 24, 2016: Heart and Vessels
https://www.readbyqxmd.com/read/27884431/computational-assessment-of-hemodynamics-based-diagnostic-tools-using-a-database-of-virtual-subjects-application-to-three-case-studies
#6
Marie Willemet, Samuel Vennin, Jordi Alastruey
Many physiological indexes and algorithms based on pulse wave analysis have been suggested in order to better assess cardiovascular function. Because these tools are often computed from in-vivo hemodynamic measurements, their validation is time-consuming, challenging, and biased by measurement errors. Recently, a new methodology has been suggested to assess theoretically these computed tools: a database of virtual subjects generated using numerical 1D-0D modeling of arterial hemodynamics. The generated set of simulations encloses a wide selection of healthy cases that could be encountered in a clinical study...
November 5, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27884238/the-pressure-of-aging
#7
REVIEW
Majd AlGhatrif, Mingyi Wang, Olga V Fedorova, Alexei Y Bagrov, Edward G Lakatta
Significant hemodynamic changes ensue with aging, leading to an ever-growing epidemic of hypertension. Alterations in central arterial properties play a major role in these hemodynamic changes. These alterations are characterized by an initial decline in aortic distensibility and an increase of diastolic blood pressure, followed by a sharp increase in pulse wave velocity (PWV), and an increase in pulse pressure (PP) beyond the sixth decade. However, the trajectories of PWV and PP diverge with advancing age...
January 2017: Medical Clinics of North America
https://www.readbyqxmd.com/read/27884226/patient-management-of-hypertensive-subjects-without-and-with-diabetes-mellitus-type-ii
#8
REVIEW
Michel E Safar, Jacques Blacher, Athanase D Protogerou
The description of blood pressure (BP) curve has evolved to include several noninvasively determined parameters, such as aortic stiffness, BP variability, wave reflections, and pulse pressure amplification. These techniques are likely to improve the efficacy of assessing pulsatile arterial hemodynamics and changes in arterial stiffness. The goal for future antihypertensive treatments should not only reduce steady BP, but also control pulsatile pressure and modify the stiffness gradient between central and peripheral arteries, which is frequently elevated...
January 2017: Medical Clinics of North America
https://www.readbyqxmd.com/read/27881851/relationships-between-24-h-blood-pressure-variability-and-24-h-central-arterial-pressure-pulse-wave-velocity-and-augmentation-index-in-hypertensive-patients
#9
Stefano Omboni, Igor N Posokhov, Anatoly N Rogoza
Twenty-four-h blood pressure variability (BPV) predicts cardiovascular complications in hypertension, but its association with pulse wave indices (central arterial pressure, pulse wave velocity (PWV) and augmentation index (AIx)) is poorly understood. In the present study, we assessed the degree of the effect of 24-h BPV on 24-h pulse wave indices. Brachial blood pressure was measured non-invasively over the 24 h with an electronic, oscillometric, automated device (BPLab) in 661 uncomplicated treated or untreated hypertensive patients...
November 24, 2016: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/27876124/estimating-the-influence-of-aortic-stent-grafts-after-endovascular-aneurysm-repair-are-we-missing-something
#10
Efstratios Georgakarakos
The implantation of a stiff aortic endograft for endovascular abdominal aneurysm repair (EVAR) has been reported to increase aortic stiffness and pulse wave velocity (PWV), raising potential concern over deterioration of myocardial performance. Yet, additional stiffness indices such as the augmentation index (AIx), reflection magnitude (RM) and changes in augmentation pressure (AP) have not been studied adequately to facilitate and improve our knowledge regarding the ways that EVAR affects central hemodynamics...
December 2016: Medical Hypotheses
https://www.readbyqxmd.com/read/27873498/the-impact-of-diabetes-mellitus-on-vascular-biomarkers-in-patients-with-end-stage-renal-disease
#11
Jeonggeun Moon, Chan Joo Lee, Sang Hak Lee, Seok Min Kang, Donghoon Choi, Tae Hyun Yoo, Sungha Park
PURPOSE: Diabetes mellitus (DM) is the most common cause of end-stage renal disease (ESRD) and an important risk factor for cardiovascular (CV) disease. We investigated the impact of DM on subclinical CV damage by comprehensive screening protocol in ESRD patients. MATERIALS AND METHODS: Echocardiography, coronary computed tomography angiogram, 24-h ambulatory blood pressure monitoring, and central blood pressure with pulse wave velocity (PWV) were performed in 91 ESRD patients from the Cardiovascular and Metabolic disease Etiology Research Center-HIgh risk cohort...
January 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/27873008/arterial-stiffness-and-peripheral-arterial-disease-in-patients-with-systemic-lupus-erythematosus
#12
Konstantinos Tziomalos, Ioannis Gkougkourelas, Alexandros Sarantopoulos, Eleni Bekiari, Evangelia Makri, Nikolaos Raptis, Konstantinos Tselios, Marianna Pantoura, Apostolos I Hatzitolios, Panagiota Boura
Systemic lupus erythematosus (SLE) is associated with increased cardiovascular risk. We aimed to evaluate arterial stiffness and the ankle brachial index (ABI), two markers of subclinical cardiovascular disease, in SLE. We studied 55 patients with SLE (12.7% males, age 53.3 ± 15.3 years) and 61 age- and gender-matched controls. Arterial stiffness was evaluated by measuring pulse wave velocity (PWV), augmentation index (AIx) and central systolic, diastolic, pulse and mean blood pressure (BP). Peripheral arterial disease was defined as ABI ≤ 0...
November 21, 2016: Rheumatology International
https://www.readbyqxmd.com/read/27861248/reliability-of-pulse-waveform-separation-analysis-effects-of-posture-and-fasting
#13
Lee Stoner, Daniel Credeur, Simon Fryer, James Faulkner, Danielle Lambrick, Bethany Barone Gibbs
OBJECTIVE: Oscillometric pulse wave analysis devices enable, with relative simplicity and objectivity, the measurement of central hemodynamic parameters. The important parameters are central blood pressures and indices of arterial wave reflection, including wave separation analysis (backward pressure component P b and reflection magnitude). This study sought to determine whether the measurement precision (between-day reliability) of P b and reflection magnitude: exceeds the criterion for acceptable reliability; and is affected by posture (supine, seated) and fasting state...
November 16, 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27859800/change-in-maternal-cardiac-output-from-pre-conception-to-mid-pregnancy-is-associated-with-birth-weight-in-healthy-pregnancies
#14
Amita A Mahendru, Fung L Foo, Carmel M McEniery, Thomas R Everett, Ian B Wilkinson, Christoph C Lees
OBJECTIVE: Birth weight (BW) is thought to be determined by maternal health, and genetic, nutritional and placental factors; the latter being influenced by anatomical development and perfusion. Maternal cardiovascular changes contribute to uteroplacental perfusion, however they have not been investigated in relation to fetal growth/BW. Our aim was to explore the relationship between maternal cardiovascular adaptation, fetal growth and BW in healthy pregnancies. METHODS: This was a longitudinal prospective study of women planning to conceive a pregnancy...
November 18, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27858374/prediction-of-fluid-responsiveness-an-update
#15
REVIEW
Xavier Monnet, Paul E Marik, Jean-Louis Teboul
In patients with acute circulatory failure, the decision to give fluids or not should not be taken lightly. The risk of overzealous fluid administration has been clearly established. Moreover, volume expansion does not always increase cardiac output as one expects. Thus, after the very initial phase and/or if fluid losses are not obvious, predicting fluid responsiveness should be the first step of fluid strategy. For this purpose, the central venous pressure as well as other "static" markers of preload has been used for decades, but they are not reliable...
December 2016: Annals of Intensive Care
https://www.readbyqxmd.com/read/27846043/aortic-stiffness-and-blood-pressure-variability-in-young-people-a-multimodality-investigation-of-central-and-peripheral-vasculature
#16
Henry Boardman, Adam J Lewandowski, Merzaka Lazdam, Yvonne Kenworthy, Polly Whitworth, Charlotte L Zwager, Jane M Francis, Christina Y L Aye, Wilby Williamson, Stefan Neubauer, Paul Leeson
INTRODUCTION: Increased blood pressure (BP) variability is a cardiovascular risk marker for young individuals and may relate to the ability of their aorta to buffer cardiac output. We used a multimodality approach to determine relations between central and peripheral arterial stiffness and BP variability. METHODS: We studied 152 adults (mean age of 31 years) who had BP variability measures based on SD of awake ambulatory BPs, 24-h weighted SD and average real variability (ARV)...
November 23, 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27843051/effect-of-hormone-replacement-therapy-with-the-anti-mineralocorticoid-progestin-drospirenone-compared-to-tibolone-on-endothelial-function-and-central-haemodynamics-in-post-menopausal-women
#17
Cristiana Vitale, Caterina Mammi, Marco Gambacciani, Novella Russo, Ilaria Spoletini, Massimo Fini, Maurizio Volterrani, Giuseppe M C Rosano
Drospirenone (DRSP) is an antialdosterone agent with progestogenic and antiandrogenic effects. This compound, has been recently used in combination with 17β-estradiol (E2) as hormonal therapy in postmenopausal women and has been shown to exert a significant antihypertensive effect in hypertensive post-menopausal women. Aim of the present study was to compare the effect of DRSP/E2 with those of Tibolone (T) on endothelial function, arterial stiffness, and lipid profile of early postmenopausal women naïve on post-menopausal hormonal therapy...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27824285/increased-central-arterial-stiffness-after-spinal-cord-injury-contributing-factors-implications-and-possible-interventions
#18
Amanda Huai Xin Lee, Aaron A Phillips, Andrei V Krassioukov
Individuals with spinal cord injury (SCI) experience life-threatening cardiovascular events and various autonomic consequences in addition to the well-appreciated motor and neurological impairments. As a result, cardiovascular disease is a major cause of death after SCI, corresponding to a 2-4 fold increased risk of cardiovascular events. A combination of neuroanatomical changes, unstable blood pressure, and rapid deconditioning as a result of decreased physical activity likely contributes to accelerated cardiovascular disease progression in after SCI...
November 8, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27823711/central-sleep-apnea-in-children-experience-at-a-single-center
#19
Orlane Felix, Alessandro Amaddeo, Jorge Olmo Arroyo, Michel Zerah, Stephanie Puget, Valerie Cormier-Daire, Genevieve Baujat, Graziella Pinto, Marta Fernandez-Bolanos, Brigitte Fauroux
OBJECTIVE: Central sleep apnea (CSA) syndromes are rare in children and data in children over one year of age are scarce. The aim of the study was to describe the sleep characteristics, underlying disorders, management, and outcome of children with CSA. PATIENTS/METHODS: A retrospective chart review of all children >1 year of age, diagnosed with CSA on a laboratory sleep study during a 20-month period, was performed. CSA was defined by a central apnea index (CAI) >5 events/h...
September 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27819747/infant-position-in-neonates-receiving-mechanical-ventilation
#20
REVIEW
May Rivas-Fernandez, Marta Roqué I Figuls, Ana Diez-Izquierdo, Joaquin Escribano, Albert Balaguer
BACKGROUND: In patients of various ages undergoing mechanical ventilation (MV), it has been observed that positions other than the standard supine position, such as the prone position, may improve respiratory parameters. The benefits of these positions have not been clearly defined for critically ill newborns receiving MV.This is an update of a review first published in 2005 and last updated in 2013. OBJECTIVES: Primary objectiveTo assess the effects of different positioning of newborn infants receiving MV (supine vs prone, lateral decubitus or quarter turn from prone) in improving short-term respiratory outcomes...
November 7, 2016: Cochrane Database of Systematic Reviews
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