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https://www.readbyqxmd.com/read/28334427/capnography-versus-standard-monitoring-for-emergency-department-procedural-sedation-and-analgesia
#1
REVIEW
Brian F Wall, Kirk Magee, Samuel G Campbell, Peter J Zed
BACKGROUND: Procedural sedation and analgesia (PSA) is used frequently in the emergency department (ED) to facilitate painful procedures and interventions. Capnography, a monitoring modality widely used in operating room and endoscopy suite settings, is being used more frequently in the ED setting with the goal of reducing cardiopulmonary adverse events. As opposed to settings outside the ED, there is currently no consensus on whether the addition of capnography to standard monitoring modalities reduces adverse events in the ED setting...
March 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28330663/longitudinal-changes-in-lv-structure-and-diastolic-function-in-relation-to-arterial-properties-in-general%C3%A2-population
#2
Nicholas Cauwenberghs, Judita Knez, Jan D'hooge, Lutgarde Thijs, Wen-Yi Yang, Fang-Fei Wei, Zhen-Yu Zhang, Jan A Staessen, Tatiana Kuznetsova
OBJECTIVES: We assessed to what extent arterial properties measured at baseline and follow-up predict longitudinal alterations in echocardiographic indexes reflecting left ventricular (LV) structure and function. BACKGROUND: Serial imaging studies are needed to clarify the relation of changes in LV structure and function to arterial stiffness. METHODS: In 607 participants (50.7% women; mean age 50.7 years), using echocardiography and Doppler imaging, we measured LV dimensions, transmitral blood flow, and mitral annular tissue velocities at baseline and after 4...
March 10, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28321055/the-relationships-between-the-differences-in-the-central-blood-pressure-and-brachial-blood-pressure-and-other-factors-in-patients-with-essential-hypertension
#3
Masaki Ryuzaki, Satoshi Morimoto, Michita Niiyama, Yasufumi Seki, Naohiro Yoshida, Yoichi Oshima, Yuki Mizuguchi, Daisuke Watanabe, Takashi Ando, Atsuhiro Ichihara
Objective The management of blood pressure (BP) in hypertensive patients is the key to preventing a progression of organ damage. The brachial BP (bBP) has been used as the representative method for measuring the BP. The central BP (cBP), which is, different from the bBP due to the propagation and the reflection of the pulse wave in the arterial system, has recently received attention because it can now be estimated non-invasively. We examined the relationships between the difference in the central systolic BP (csBP) and the brachial systolic BP (bsBP) (Δ) and other factors in hypertensive patients...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28290893/-hronotherapy-aspects-of-efficiency-azilsartan-medoxomil-in-combination-therapy-in-patients-with-hypertension-and-metabolic-syndrome
#4
V V Skibitskiy, A V Fendrikova, D V Sirotenko, A V Skibitskiy
OBJECTIVE: Determination of the effectiveness and safety of different dosing regimens during the day (in the morning or at bedtime) combination therapy including azilsartan medoxomil in patients with essential hypertension and metabolic syndrome (MS). DESIGN AND METHODS: The study included 60 patients with uncontrolled hypertension and MS (age median - 59 (54-65) years). Patients were randomized in two groups: group 1 (n=30) received azilsartan medoxomil 40 mg/day, and indapamide retard 1,5 mg/day in the morning; group 2 (n=30)- azilsartan medoxomoil 40 mg at bedtime and indapamide retard 1,5 mg in the morning...
October 2016: Kardiologiia
https://www.readbyqxmd.com/read/28290783/-optimization-of-control-of-blood-pressure-metabolic-disorders-and-target-organs-protection-with-fixed-perindopril-and-indapamide-combination-in-treated-patients-with-arterial-hypertension
#5
S V Nedogoda, E V Chumachek, A A Ledyaeva, V V Tsoma, A S Salasyuk, V O Smirnova, V Ju Hripaeva, R V Palashkin
PURPOSE: to assess the potential of fixed perindopril/indapamide combination (FPIC) to improve angioprotection in patients with arterial hypertension (AP) with various efficacy of preceding therapy with combination of losartan and hydrochlorothiazide (HCTZ). MATERIAL AND METHODS: We included in this open study 50 patients with AP divided into two equal-sized groups in dependence on the achievement of target blood pressure (BP) less than 140/90 mm Hg on preceding therapy with losartan (100 mg) and HCTZ (12...
February 2017: Kardiologiia
https://www.readbyqxmd.com/read/28289784/high-blood-pressure-states-in-children-adolescents-and-young-adults-associate-accelerated-vascular-aging-with-a-higher-impact-in-females-arterial-properties
#6
S Curcio, V García-Espinosa, J M Castro, G Peluso, M Marotta, M Arana, P Chiesa, G Giachetto, D Bia, Yanina Zócalo
The aims of the study were to determine (1) whether the presence of High blood pressure (HBP) states in the youth associate a steeper rate of age-related change in arterial geometrical and wall properties with respect to subjects with no previous cardiovascular risk factor (CRF) exposure, (2) in which parameters and in what magnitude, and (3) the existence of a gender-related difference in the impact of this condition on arterial properties. 300 individuals (mean/range: 15/4-29 years; 133 females) were included...
March 13, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28285656/relationships-of-insulin-like-growth-factor-1-its-binding-proteins-and-cardiometabolic-risk-in-hypertensive-perimenopausal-women
#7
Agnieszka Olszanecka, Aneta Dragan, Kalina Kawecka-Jaszcz, Danuta Fedak, Danuta Czarnecka
PURPOSE: During the transition from premenopause to postmenopause, many women experience weight gain and central fat deposition; therefore, we hypothesized that circulating growth factors can play a role in the pathogenesis of hypertension, metabolic syndrome, and subclinical organ damage in perimenopausal women. BASIC PROCEDURES: The study included 192 women aged 40 to 60years; 152 had newly diagnosed essential hypertension that had never been treated, and 40 were normotensive age-matched controls...
April 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28281031/pulse-transit-time-as-a-tool-to-characterize-obstructive-and-central-apneas-in-children
#8
Lucie Griffon, Alessandro Amaddeo, Jorge Olmo Arroyo, Rossana Tenconi, Serena Caggiano, Sonia Khirani, Brigitte Fauroux
PURPOSE: The characterization of apneas during polysomnography (PSG) as obstructive or central is a key element of a sleep study. Pulse transit time (PTT) has demonstrated its potential as a noninvasive surrogate marker for inspiratory efforts. The aim of the study was to assess the ability of PTT to classify apneas as central or obstructive, as compared to respiratory inductance plethysmography (RIP) in children. METHODS: Overnight PSG with simultaneous PTT recording was performed on 11 consecutive children (mean age 8...
March 9, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28268404/a-temperature-controlled-glove-with-non-invasive-arterial-pulse-sensing-for-active-neuro-vascular-assessment
#9
Andrew M Carek, Omer T Inan
A non-invasive, active neuro-vascular assessment system was developed using a modified temperature-controlled glove and feedback techniques. The glove incorporates local heating and cooling of the hand using multi-point skin temperature measurements as feedback, and thereby induces local and central mechanisms involved in thermoregulation. Electrocardiogram (ECG), photoplethysmogram (PPG) and non-invasive finger-cuff based blood pressure (BP) measurements were used to monitor electrophysiology and hemodynamic changes in response to temperature modulation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28260186/efficacy-of-zofenopril-vs-irbesartan-in-combination-with-a-thiazide-diuretic-in-hypertensive-patients-with-multiple-risk-factors-not-controlled-by-a-previous-monotherapy-a-review-of-the-double-blind-randomized-z-studies
#10
REVIEW
Stefano Omboni, Ettore Malacco, Claudio Napoli, Pietro Amedeo Modesti, Athanasios Manolis, Gianfranco Parati, Enrico Agabiti-Rosei, Claudio Borghi
Combinations between an angiotensin converting enzyme (ACE) inhibitor or an angiotensin II receptor blocker (ARB) and hydrochlorothiazide (HCTZ) are among the recommended treatments for hypertensive patients uncontrolled by monotherapy. Four randomized, double-blind, parallel group studies with a similar design, including 1469 hypertensive patients uncontrolled by a previous monotherapy and with ≥1 cardiovascular risk factor, compared the efficacy of a combination of a sulfhydryl ACE inhibitor (zofenopril at 30 or 60 mg) or an ARB (irbesartan at 150 or 300 mg) plus HCTZ 12...
March 4, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28256104/haemodynamic-influences-of-bisoprolol-in-hypertensive-middle-aged%C3%A2-men-a%C3%A2-double-blind-randomized-placebo-controlled-cross-over-study
#11
Lauri Suojanen, Antti Haring, Antti Tikkakoski, Jenni K Koskela, Anna M Tahvanainen, Heini Huhtala, Mika Kähönen, Kalle Sipilä, Arttu Eräranta, Jukka T Mustonen, Kari Kivistö, Ilkka H Pörsti
Treatment with beta-blockers appears to show inferior reduction of central versus peripheral blood pressure. We aimed to examine simultaneous changes in central and peripheral blood pressure, vascular resistance, cardiac function and arterial stiffness during beta-blockade. Haemodynamics were investigated after 3 weeks of bisoprolol treatment (5 mg/d) in a double-blind, randomized, placebo-controlled cross-over trial in never-treated 16 Caucasian males with grade I-II primary hypertension using continuous tonometric pulse wave analysis and whole-body impedance cardiography...
March 2, 2017: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28253850/pulmonary-hypertension-attenuates-the-dynamic-preload-indicators-increase-during-experimental-hypovolemia
#12
Juan P Bouchacourt, Juan Riva, Juan C Grignola
BACKGROUND: Pulse pressure (PPV) and stroke volume (SVV) variations may not be reliable in the setting of pulmonary hypertension and/or right ventricular (RV) failure. We hypothesized that RV afterload increase attenuates SVV and PPV during hypovolemia in a rabbit model of pulmonary embolism (PE) secondary to RV dysfunction. METHODS: Seven anesthetized and mechanically ventilated rabbits were studied during four experimental conditions: normovolemia, blood withdrawal, pulmonary embolism and fluid loading of a colloidal solution...
March 3, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28253335/effects-of-age-associated-regional-changes-in-aortic-stiffness-on-human-hemodynamics-revealed-by-computational-modeling
#13
Federica Cuomo, Sara Roccabianca, Desmond Dillon-Murphy, Nan Xiao, Jay D Humphrey, C Alberto Figueroa
Although considered by many as the gold standard clinical measure of arterial stiffness, carotid-to-femoral pulse wave velocity (cf-PWV) averages material and geometric properties over a large portion of the central arterial tree. Given that such properties may evolve differentially as a function of region in cases of hypertension and aging, among other conditions, there is a need to evaluate the potential utility of cf-PWV as an early diagnostic of progressive vascular stiffening. In this paper, we introduce a data-driven fluid-solid-interaction computational model of the human aorta to simulate effects of aging-related changes in regional wall properties (e...
2017: PloS One
https://www.readbyqxmd.com/read/28250414/relationships-between-urinary-electrolytes-excretion-and-central-hemodynamics-and-arterial-stiffness-in-hypertensive-patients
#14
Weizhong Han, Xiao Han, Ningling Sun, Yunchao Chen, Shiliang Jiang, Min Li
High sodium intake plays an important role in the onset and exacerbation of hypertension. However, the relationships between urinary electrolytes excretion and central hemodynamics and between urinary electrolyte excretion and arterial stiffness are still the subject of debate. This study sought to clarify the associations of salt intake with central aortic pressure and arterial stiffness indicators. A total of 431 untreated hypertensive individuals were recruited into the study. Twenty-four-hour urinary samples were collected to measure the excretion of urinary electrolytes...
March 2, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28248531/baseline-values-of-cardiovascular-and-respiratory-parameters-predict-response-to-acute-hypoxia-in-young-healthy-men
#15
V N Melnikov, S G Krivoschekov, V E Divert, T G Komlyagina, N S Consedine
The majority of the available works have studied distinct hypoxic responses of respiratory and cardiovascular systems. This study examines how these systems interact while responding to hypoxia and whether baseline metrics moderate reactions to a hypoxic challenge. Central hemodynamic, aortic wave reflection, and gas exchange parameters were measured in 27 trained young men before and after 10-min normobaric isocapnic hypoxia (10 % O2). Associations were assessed by correlation and multiple regression analyses...
February 28, 2017: Physiological Research
https://www.readbyqxmd.com/read/28244635/effect-of-linagliptin-on-pulse-wave-velocity-in-early-type-2-diabetes-release-a-randomized-double-blind-controlled-26-week-trial
#16
Stefanie A de Boer, Hiddo J L Heerspink, Luis E Juárez Orozco, Arie M van Roon, Pieter W Kamphuisen, Andries J Smit, Riemer H J A Slart, Joop D Lefrandt, Douwe J Mulder
AIMS: To evaluate the effects of the DPP-4 inhibitor linagliptin on aortic pulse wave velocity (PWV) as a surrogate marker of arterial stiffness and early atherosclerosis in early type 2 diabetes subjects. MATERIALS AND METHODS: A total of 45 type 2 diabetes subjects (median age 63 (IQR: 54-66) years, 61% male, mean hemoglobinA1c (HbA1c ) 6.3 ± 0.4 % (45 ± 4.6 mmol/mol)) without cardiovascular disease and naïve to antidiabetic treatment were randomized (1:1) to treatment with linagliptin 5 mg once daily or placebo for 26 weeks in a double-blind fashion...
February 28, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28237937/investigation-of-viscoelasticity-in-the-relationship-between-carotid-artery-blood-pressure-and-distal-pulse-volume-waveforms
#17
Jong Chan Lee, Zahra Ghasemi, Chang-Sei Kim, Hao-Min Cheng, Chen-Huan Chen, Shih-Hsien Sung, Ramakrishna Mukkamala, Jin-Oh Hahn
We investigated the relationship between carotid artery blood pressure (BP) and distal pulse volume waveforms (PVRs) via subject-specific mathematical modeling. We conceived three physical models to define the relationship: a tube-load model augmented with a gain (TLG), Voigt (TLV) and standard linear solid (TLS) models. We compared these models using PVRs measured via BP cuffs at an upper arm and an ankle as well as carotid artery tonometry waveform collected from 133 subjects. At both upper arm and ankle, PVR was related to carotid artery tonometry by TLV and TLS models better than by TLG model; when root-mean-squared over all the subjects, the systolic and diastolic BP errors between measured carotid artery tonometry waveform and the one estimated from distal PVR reduced from 4...
February 22, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28231259/impact-of-seasonality-and-air-pollutants-on-carotid-femoral-pulse-wave-velocity-and-wave-reflection-in-hypertensive-patients
#18
Marina Di Pilla, Rosa Maria Bruno, Francesco Stea, Luciano Massetti, Stefano Taddei, Lorenzo Ghiadoni, Pietro Amedeo Modesti
OBJECTIVE: The effects of seasonality on blood pressure (BP) and cardiovascular (CV) events are well established, while the influence of seasonality and other environmental factors on arterial stiffness and wave reflection has never been analyzed. This study evaluated whether seasonality (daily number of hours of light) and acute variations in outdoor temperature and air pollutants may affect carotid-femoral pulse wave velocity (PWV) and pressure augmentation. DESIGN AND METHOD: 731 hypertensive patients (30-88 years, 417 treated) were enrolled in a cross-sectional study during a 5-year period...
2017: PloS One
https://www.readbyqxmd.com/read/28229053/large-artery-stiffness-assessment-using-sphygmocor-technology
#19
REVIEW
Mark Butlin, Ahmad Qasem
Large artery stiffness assessment has been an integral part of the SphygmoCor technology since 1998. Aortic stiffness is approximated with non-invasive measurement of carotid-femoral pulse wave velocity, with improvements made with time to make the assessment procedure quicker and more user independent. Also standard in the devices is the ability to reliably calculate the central aortic waveform shape from a peripheral pressure waveform from either the brachial or radial artery. This waveform contains much information beyond peak and trough (systolic and diastolic pressure)...
January 2017: Pulse (Basel, Switzerland)
https://www.readbyqxmd.com/read/28226574/a-temperature-controlled-glove-with-non-invasive-arterial-pulse-sensing-for-active-neuro-vascular-assessment
#20
Andrew M Carek, Omer T Inan, Andrew M Carek, Omer T Inan, Andrew M Carek, Omer T Inan
A non-invasive, active neuro-vascular assessment system was developed using a modified temperature-controlled glove and feedback techniques. The glove incorporates local heating and cooling of the hand using multi-point skin temperature measurements as feedback, and thereby induces local and central mechanisms involved in thermoregulation. Electrocardiogram (ECG), photoplethysmogram (PPG) and non-invasive finger-cuff based blood pressure (BP) measurements were used to monitor electrophysiology and hemodynamic changes in response to temperature modulation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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