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https://www.readbyqxmd.com/read/28718166/can-long-term-luts-bph-pharmacological-treatment-alter-the-outcomes-of-surgical-intervention
#1
REVIEW
Fabrizio Presicce, Cosimo De Nunzio, Andrea Tubaro
PURPOSE OF REVIEW: We have reviewed the available evidence on the impact of long-term pharmacological treatment of lower urinary tract symptoms on the outcomes of benign prostatic hyperplasia surgery. EVIDENCE ACQUISITION: A systematic literature search from January 1990 to May 2017 was performed. Only references in the English language and peer-reviewed manuscripts were considered. RECENT FINDINGS: Over time, the ever-increasing use of long-term pharmaceutical treatments has considerably reduced the rate of BPH surgery in most countries...
September 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28699992/changes-in-frailty-conditions-and-phenotype-components-in-elderly-after-hospitalization
#2
Gianna Fiori Marchiori, Darlene Mara Dos Santos Tavares
Objective: describing the changes in frailty conditions over the period of a year after hospital discharge, verifying predictive variables for changes in frailty conditions and frailty phenotype components according to worsening, improving and stable groups. Method: a longitudinal survey carried out with 129 elderly. A structured form for socioeconomic and health data, scales (Geriatric Depression Scale - short form, Katz scale, Lawton and Brody scale) and frailty phenotype according to Fried were used...
July 10, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28678057/hyaluronidase-assisted-resuscitation-in-kenya-for-severely-dehydrated-children
#3
Hijab Zubairi, Brett D Nelson, Priyanka Tulshian, Karla Fredricks, Zaid Altawil, Sarah Mireles, Fred Odongo, Thomas F Burke
BACKGROUND: Dehydration, mainly due to diarrheal illnesses, is a leading cause of childhood mortality worldwide. Intravenous (IV) therapy is the standard of care for patients who were unable to tolerate oral rehydration; however, placing IVs in fragile, dehydrated veins can be challenging. Studies in resource-rich settings comparing hyaluronidase-assisted subcutaneous rehydration with standard IV rehydration in children have demonstrated several benefits of subcutaneous rehydration, including time and success of line placement, ease of use, satisfaction, and cost-effectiveness...
July 4, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28677166/prediction-of-fractures-and-major-cardiovascular-events-in-men-using-serum-osteoprotegerin-levels-the-prospective-strambo-study
#4
Pawel Szulc, Roland Chapurlat, Lorenz C Hofbauer
Fragility fractures and cardiovascular diseases often coincide. However, data on shared risk factors and markers are scarce. Our aim was to assess the independent associations of serum osteoprotegerin (OPG) levels with the risk of fracture and cardiovascular outcomes (acute coronary syndrome, cardiac death) in older men. A cohort of 819 home-dwelling men aged 60-87 was followed prospectively for 8 years. Serum OPG was measured at baseline by ELISA. Bone mineral density (BMD) at femoral neck and Trabecular Bone Score (TBS) were assessed by DXA...
July 4, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28672133/unstable-fragility-fractures-of-the-ankle-in-the-elderly-transarticular-steinmann-pin-or-external-fixation
#5
R P J Meijer, J A Halm, T Schepers
INTRODUCTION: Because of poor skin conditions and comorbidity, open reduction and internal fixation in ankle fractures is frequently contra-indicated in the elderly. This study reports the results of two temporary fixation types in fragility fractures in the older patient: transarticular Steinmann pin fixation and external fixation. METHODS: Patients aged over 60 treated with a Steinmann pin or external fixation were retrospectively included. Patient, fracture and treatment characteristics were collected...
April 27, 2017: Foot
https://www.readbyqxmd.com/read/28660188/microrna-in-cardiovascular-aging-and-age-related-cardiovascular-diseases
#6
REVIEW
Claudio de Lucia, Klara Komici, Giulia Borghetti, Grazia Daniela Femminella, Leonardo Bencivenga, Alessandro Cannavo, Graziamaria Corbi, Nicola Ferrara, Steven R Houser, Walter J Koch, Giuseppe Rengo
Over the last decades, life expectancy has significantly increased although several chronic diseases persist in the population, with aging as the leading risk factor. Despite improvements in diagnosis and treatment, many elderlies suffer from cardiovascular problems that are much more frequent in an older, more fragile organism. In the long term, age-related cardiovascular diseases (CVDs) contribute to the decline of quality of life and ability to perform normal activities of daily living. microRNAs (miRNAs) are a class of small non-coding RNAs that regulate gene expression at the posttranscriptional level in both physiological and pathological conditions...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28656564/high-prevalence-of-missed-opportunities-for-secondary-fracture-prevention-in-a-regional-general-hospital-setting-in-singapore
#7
Linsey Gani, Saripalli K Reddy, Rayan Alsuwaigh, Joan Khoo, Thomas F J King
This study aims at assessing the gap in secondary fracture prevention at a regional general hospital setting in Singapore. Male patients have significantly lower rate of being investigated and treated for osteoporosis than their female counterparts. Vitamin D deficiency is prevalent in our population. PURPOSE: Secondary fracture prevention services are not routine in Singapore; we seek to assess the treatment gap that exists in the lack of diagnosis and treatment of osteoporosis in fragility fracture patients...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28650253/diagnosis-and-treatment-of-osteoporosis-before-and-after-fracture-a-side-by-side-analysis-of-commercially-insured-and-medicare-advantage-osteoporosis-patients
#8
Jessica Weaver, Shiva Sajjan, E Michael Lewiecki, Steven T Harris
BACKGROUND: Although treatment for osteoporosis is recommended by U.S. clinical guidelines, a lack of diagnosis and treatment is common among patients with osteoporotic fractures. OBJECTIVE: To determine the rates of osteoporosis diagnosis and treatment before and after various types of fractures. METHODS: This was a retrospective claims analysis using data from the Humana Medicare Advantage claims (Medicare group) and Optum Insight Clinformatics Data Mart commercial claims (Commercial group)...
July 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28634634/pain-and-fracture-related-limitations-persist-6%C3%A2-months-after-a-fragility-fracture
#9
Joanna E M Sale, Lucy Frankel, Stephen Thielke, Larry Funnell
Our objective was to examine the experience of pain after a fracture beyond the conventional healing duration of 6 months. We conducted a phenomenological study in participants who were deemed high risk for future fracture and recruited through an urban fracture clinic in Toronto, Canada. In-depth interviews were conducted with questions addressing the experience of pain, the status of recovery from the fracture, ways in which the fracture affected one's daily activities, and interactions with health care providers...
June 20, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28634578/neonatal-venous-thromboembolism
#10
REVIEW
Kristina M Haley
Neonates are the pediatric population at highest risk for development of venous thromboembolism (VTE), and the incidence of VTE in the neonatal population is increasing. This is especially true in the critically ill population. Several large studies indicate that the incidence of neonatal VTE is up almost threefold in the last two decades. Central lines, fluid fluctuations, sepsis, liver dysfunction, and inflammation contribute to the risk profile for VTE development in ill neonates. In addition, the neonatal hemostatic system is different from that of older children and adults...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28620287/changes-of-eeg-spectra-and-functional-connectivity-during-an-object-location-memory-task-in-alzheimer-s-disease
#11
Yuliang Han, Kai Wang, Jianjun Jia, Weiping Wu
Object-location memory is particularly fragile and specifically impaired in Alzheimer's disease (AD) patients. Electroencephalogram (EEG) was utilized to objectively measure memory impairment for memory formation correlates of EEG oscillatory activities. We aimed to construct an object-location memory paradigm and explore EEG signs of it. Two groups of 20 probable mild AD patients and 19 healthy older adults were included in a cross-sectional analysis. All subjects took an object-location memory task. EEG recordings performed during object-location memory tasks were compared between the two groups in the two EEG parameters (spectral parameters and phase synchronization)...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28618112/older-patients-with-late-stage-copd-their-illness-experiences-and-involvement-in-decision-making-regarding-mechanical-ventilation-and-noninvasive-ventilation
#12
Heidi Jerpseth, Vegard Dahl, Per Nortvedt, Kristin Halvorsen
Older patients with late-stage COPD: their illness experiences and involvement in decision-making regarding mechanical ventilation and noninvasive ventilation AIMS AND OBJECTIVES: The aim of this study was twofold: first, to explore the illness experiences of older patients' with late-stage chronic obstructive pulmonary disease; and second, to develop knowledge about how patients perceive their preferences to be taken into account in decision-making processes concerning mechanical ventilation and /or non-invasive ventilation...
June 15, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28613988/cost-effectiveness-of-virtual-bone-strength-testing-in-osteoporosis-screening-programs-for-postmenopausal-women-in-the-united-states
#13
Christoph A Agten, Austin J Ramme, Stella Kang, Stephen Honig, Gregory Chang
Purpose To investigate whether assessment of bone strength with quantitative computed tomography (CT) in combination with dual-energy x-ray absorptiometry (DXA) is cost-effective as a screening tool for osteoporosis in postmenopausal women. Materials and Methods A state-transition microsimulation model of osteoporosis for postmenopausal women aged 55 years or older was developed with a lifetime horizon and U.S. societal perspective. All model inputs were derived from published literature. Three strategies were compared: no screening, DXA with T score-dependent rescreening intervals, and a combination of DXA and quantitative CT with different intervals (3, 5, and 10 years) at different screening initiation ages (55-65 years)...
June 14, 2017: Radiology
https://www.readbyqxmd.com/read/28611110/the-liftmor-m-lifting-intervention-for-training-muscle-and-osteoporosis-rehabilitation-for-men-trial-protocol-for-a-semirandomised-controlled-trial-of-supervised-targeted-exercise-to-reduce-risk-of-osteoporotic-fracture-in-older-men-with-low-bone-mass
#14
Amy T Harding, Benjamin K Weeks, Steven L Watson, Belinda R Beck
INTRODUCTION: The primary aim of the proposed study is to examine the efficacy of an 8-month supervised, high-intensity progressive resistance training and impact loading programme in comparison with a supervised machine-based isometric exercise training programme using the bioDensity system in older men with low bone mass. We will also determine the safety and acceptability of each exercise training mode. Intervention group responses will be compared with those of a self-selected, non-randomised control sample of sex-matched and age-matched men who will follow their usual lifestyle activities for 8 months...
June 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/28585054/the-effects-of-person-centered-or-other-supportive-interventions-in-older-women-with-osteoporotic-vertebral-compression-fractures-a-systematic-review-of-the-literature
#15
REVIEW
H K Svensson, L -E Olsson, T Hansson, J Karlsson, E Hansson-Olofsson
Vertebral compression fracture (VCF) is a common fragility fracture and the starting point of a lasting, painful, disabling condition. The aim was to summarize evidence of person-centered/non-medical interventions supporting women with VCF. Results show small numbers of studies with only probable effect on function, pain, QoL, fear of falling, and psychological symptoms. The vertebral compression fracture (VCF) caused by osteoporosis is the third most common fragility fracture worldwide. Previously, it was believed that the pain caused by VCF was self-subsiding within weeks or a few months post-fracture...
June 6, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28566205/internationally-adopted-children-with-cleft-lip-and-or-palate-a-retrospective-cohort-study
#16
C L Werker, H de Wilde, A B Mink van der Molen, C C Breugem
OBJECTIVE: The treatment approach for internationally adopted children with cleft lip and/or palate differs from locally born children with cleft lip and/or palate. They are older at initial presentation, may have had treatment abroad of different quality, and are establishing new and still fragile relationships with their adoptive parents. The aim of this study was to describe the characteristics and initial care and treatment of this group. METHODS: A retrospective cohort study was performed including all internationally adopted children with cleft lip and/or palate presenting to the cleft team outpatient clinic in the Wilhelmina Children's Hospital between January 1994 and December 2014...
April 23, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28566092/increased-fragility-fracture-risk-in-korean-women-who-snore-a-10-year-population-based-prospective-cohort-study
#17
Soo Beom Choi, Il Suk Lyu, Wanhyung Lee, Deok Won Kim
BACKGROUND: Snoring is frequently associated with obstructive sleep apnea (OSA). Previous studies have shown that bone mineral density was significantly lower in patients with OSA than in controls; however, these studies did not focus on fractures. Fragility fractures can lead to long-term disabilities and a decrease in quality of life. The present study aimed to investigate the association between snoring and fragility fractures. METHODS: This study included 2969 men and 3220 women aged 40 years and older from the Ansung and Ansan cohort studies in Korea...
May 31, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28555367/subtrochanteric-fractures-in-elderly-people-treated-with-intramedullary-fixation-quality-of-life-and-complications-following-open-reduction-and-cerclage-wiring-versus-closed-reduction
#18
Pablo Codesido, Ana Mejía, Jonathan Riego, Cristina Ojeda-Thies
INTRODUCTION: Subtrochanteric fractures are more difficult to treat than other proximal femoral fractures. The aim of this study was to report the outcomes for patients with subtrochanteric fractures treated using a cephalomedullary nail following open reduction and cerclage wiring versus closed reduction alone, regarding health-related quality of life (HRQoL) and social function. MATERIALS AND METHODS: We performed a prospective cohort study including patients aged 60 years or older suffering fragility subtrochanteric fractures of the femur treated with cephalomedullary nails, with a minimum 2-year follow-up...
May 29, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28555104/tdcs-over-the-motor-cortex-shows-differential-effects-on-action-and-object-words-in-associative-word-learning-in-healthy-aging
#19
Meret Branscheidt, Julia Hoppe, Nils Freundlieb, Pienie Zwitserlood, Gianpiero Liuzzi
Healthy aging is accompanied by a continuous decline in cognitive functions. For example, the ability to learn languages decreases with age, while the neurobiological underpinnings for the decline in learning abilities are not known exactly. Transcranial direct current stimulation (tDCS), in combination with appropriate experimental paradigms, is a well-established technique to investigate the mechanisms of learning. Based on previous results in young adults, we tested the suitability of an associative learning paradigm for the acquisition of action- and object-related words in a cohort of older participants...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28498173/the-meaning-of-confidence-for-older-people-living-with-frailty-a-qualitative-systematic-review
#20
Frazer Underwood, Lisa Burrows, Rod Gegg, Jos M Latour, Bridie Kent
BACKGROUND: In many countries, the oldest old (those aged 85 years and older) are now the fastest growing proportion of the total population. This oldest population will increasingly be living with the clinical condition of frailty. Frailty syndromes negatively impact on the person as they do the healthcare systems supporting them. Within healthcare literature "loss of confidence" is occasionally connected to older people living with frailty, but ambiguously described. Understanding the concept of confidence within the context of frailty could inform interventions to meet this growing challenge...
May 2017: JBI Database of Systematic Reviews and Implementation Reports
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