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https://www.readbyqxmd.com/read/28068634/virgin-coconut-oil-supplementation-attenuates-acute-chemotherapy-hepatotoxicity-induced-by-anticancer-drug-methotrexate-via-inhibition-of-oxidative-stress-in-rats
#1
Ademola C Famurewa, Odomero G Ufebe, Chima A Egedigwe, Onyebuchi E Nwankwo, Godwin S Obaje
BACKGROUND: The emerging health benefit of virgin coconut oil (VCO) has been associated with its potent natural antioxidants; however, the antioxidant and hepatoprotective effect of VCO against methotrexate-induced liver damage and oxidative stress remains unexplored. The study explored the antioxidant and hepatoprotective effects of VCO against oxidative stress and liver damage induced by anticancer drug methotrexate (MTX) in rats. METHODS: Liver damage was induced in Wistar rats pretreated with dietary supplementation of VCO (5% and 15%) by intraperitoneal administration of MTX (20mg/kg bw) on day 10 only...
January 6, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28049927/hypolipidemic-and-hypocholesterolemic-effect-of-roselle-hibiscus-sabdariffa-l-seeds-oil-in-experimental-male-rats
#2
Rehab F M Ali, Ayman M El-Anany
The current investigation aimed to evaluate the influence of roselle seeds oil (RSO), coconut oil (CNO) and binary mixture of them on serum lipids of experimental rats. Fatty acid composition of native and blended oils was determined. Thirty five male Albino rats (145- 160 g) were used throughout this study. The rats were fed AIN-93G diet containing 10% fat from CNO, RSO, B1 (25%RSO+ 75 %CNO), B2 (50 %RSO+ 50 %CNO or B3 (75 %RSO+ 25 % CNO) for eight weeks. Blood samples were collected at the beginning, every two weeks during the experiment, and at the end of the experiment...
2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28039635/alkyl-amine-and-vegetable-oil-mixture-a-viable-candidate-for-co2-capture-and-utilization
#3
A Uma Maheswari, K Palanivelu
In this present work, the absorption of CO2 in alkyl amines and vegetable oil mixture has been evaluated. The results showed that the absorption is higher in alkyl amines and vegetable oil mixture compared with the aqueous alkyl amines. In addition to that, by employing the greener and non-toxic vegetable oil media, the CO2 gas has been captured as well as converted into value-added products, such as carbamates of ethylenediamine, diethylenetriamine, and triethylenetetramine. The carbamates have been isolated and characterized by Fourier transform infrared and (1)H and (13)C nuclear magnetic resonance spectroscopic techniques...
December 30, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28038753/chemical-and-plasma-surface-modification-of-lignocellulose-coconut-waste-for-the-preparation-of-advanced-biobased-composite-materials
#4
Suheyla Kocaman, Mustafa Karaman, Mehmet Gursoy, Gulnare Ahmetli
In this study, surface-modified grinded coconut waste (CW) particles were used as bio-fillers to prepare polymeric composite materials with enhanced properties. Epoxy resin modified with acrylated and epoxidized soybean oil (AESO) was used as the polymer matrix. Two different strategies, namely chemical treatment and plasma enhanced chemical vapor deposition (PECVD) were utilized to modify the surface of CW particles for using them as compatible bio-fillers in composite preparation. Chemical modification involved the treatment of CW particles in a highly alkali NaOH solution, while PECVD modification involved coating of a thin film of hydrophobic poly(hexafluorobutyl acrylate) (PHFBA) around individual CW particle surfaces...
March 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27987169/using-tropgenedb-a-database-containing-data-on-molecular-markers-qtls-maps-genotypes-and-phenotypes-for-tropical-crops
#5
Manuel Ruiz, Guilhem Sempéré, Chantal Hamelin
TropGeneDB ( http://tropgenedb.cirad.fr ) is a web database that manages genomic, genetic, and phenotypic information on tropical crops. It is organized on a crop basis with currently nine public modules: banana, cocoa, coconut, coffee, cotton, oil palm, rice, rubber tree, and sugarcane. TropGeneDB contains data on molecular markers, quantitative trait loci (QTLs), genetic and physical maps, genotyping and phenotyping studies, and information on genetic resources (geographic origin, parentage, collection). Crop-specific web interfaces have been designed to allow quick consultations as well as personalized complex queries...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27966722/effects-of-liquid-oil-vs-oleogel-co-ingested-with-a-carbohydrate-rich-meal-on-human-blood-triglycerides-glucose-insulin-and-appetite
#6
Sze-Yen Tan, Elaine Wan-Yi Peh, Alejandro G Marangoni, Christiani Jeyakumar Henry
We examined the differences in how coconut oil in a liquid or oleogel form affects blood triglycerides, glucose, insulin, and appetite when co-ingested with a carbohydrate-rich meal. This was a randomised, controlled, crossover study where eligible participants attended a screening visit where baseline demographics were measured. On test days, participants arrived at the laboratory after an overnight fast of 10 hours. Upon arrival, cannulation of the antecubital vein was performed and fasting capillary blood glucose, plasma insulin and triglyceride levels, and appetite sensations were measured...
December 14, 2016: Food & Function
https://www.readbyqxmd.com/read/27925034/formulation-and-in-vitro-evaluation-of-carbopol-934-based-modified-clotrimazole-gel-for-topical-application
#7
Muhammad Ubaid, Sadaf Ilyas, Sadullah Mir, Abida K Khan, Rehana Rashid, Muhammad Z U Khan, Zainab G Kanwal, Ahmad Nawaz, Amna Shah, Ghulam Murtaza
The aim of present study was to enhance topical permeation of clotrimazole gel preparation by using various permeability enhancers such as coconut oil, pistachio oil and sodium lauryl sulphate (SLS). Clotrimazole gel preparations were prepared and optimized by using three factor, five level central composite design. A second-order polynomial equation was generated in order to estimate the effect of independent variables i.e. coconut oil (X1), pistachio oil (X2) and sodium lauryl sulphate (X3) at various dependent variables i...
October 2016: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/27899137/ethnobotanical-survey-of-cosmetic-plants-used-in-marquesas-islands-french-polynesia
#8
Xénia Jost, Jean-Luc Ansel, Gaël Lecellier, Phila Raharivelomanana, Jean-François Butaud
BACKGROUND: Cosmetic plants and their uses have often been neglected in ethnobotanical surveys which focus mainly on plants with medicinal or food uses. Thus, this survey was carried out to specifically investigate cosmetics in a small community and to establish a cosmetopoeia, based on the model of pharmacopoeia for medicinal plants. The geographic spread of the survey covered the Marquesas Islands, one of the five archipelagos of French Polynesia (Pacific Ocean). This archipelago was also recently investigated for its pharmacopoeia...
November 29, 2016: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/27891311/comparison-of-antibacterial-efficacy-of-coconut-oil-and-chlorhexidine-on-streptococcus-mutans-an-in-vivo-study
#9
Faizal C Peedikayil, Vimal Remy, Seena John, T P Chandru, Prathima Sreenivasan, Gufran Ahmed Bijapur
AIMS: Streptococcus mutans is the most common organism causing dental caries. Various chemotherapeutic agents are available that help in treating the bacteria, with each having their own merits and demerits. Recent research has shown that coconut oil has anti-inflammatory and antimicrobial action. Therefore, the present was conducted to determine the antibacterial efficacy of coconut oil and to compare it with chlorhexidine. MATERIALS AND METHODS: A total of fifty female children aged 8-12 years were included in the study...
September 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/27878500/anti-inflammatory-and-antioxidant-effect-of-kerabala-a-value-added-ayurvedic-formulation-from-virgin-coconut-oil-inhibits-pathogenesis-in-adjuvant-induced-arthritis
#10
M Ratheesh, S Sandya, C Pramod, S Asha, Jose P Svenia, S Premlal, B GrishKumar
Kerabala (CB) is a novel ayurvedic formulation used for treating various inflammatory diseases. This formulation was made from virgin coconut oil and it comprises extracts of Sida cordifolia, coconut milk and sesame oil. The current study was performed to evaluate the anti-inflammatory action of CB on carrageenan-induced acute and adjuvant-induced chronic experimental models. 5 mg/kg bwt was found to be potent dose from carrageenan model and evaluated its effect in adjuvant-induced chronic arthritic model...
November 22, 2016: Inflammopharmacology
https://www.readbyqxmd.com/read/27845808/use-of-complementary-health-approaches-in-individuals-with-parkinson-s-disease
#11
Ju Young Shin, Ryan T Pohlig, Barbara Habermann
Parkinson's disease (PD) is neurodegenerative and requires ongoing therapy. The purpose of the current study was two-fold: to (a) describe the prevalence, types, and associated factors of complementary health approaches (CHA) used in individuals with PD; and (b) explore reasons for CHA use. A self-administered, cross-sectional survey was used. The response rate was 61.9% (N = 135), and 74.1% of participants used CHA for either PD or general health. The most widely used CHA included exercise, yoga, massage, vitamins, coenzyme Q10, and coconut oil...
November 15, 2016: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/27818734/coconut-oil-extract-mitigates-testicular-injury-following-adjuvant-treatment-with-antiretroviral-drugs
#12
Oluwatosin O Ogedengbe, Ayoola I Jegede, Ismail O Onanuga, Ugochukwu Offor, Edwin Cs Naidu, Aniekan I Peter, Onyemaechi O Azu
Increased access to highly active antiretroviral therapy (HAART) has made the management of drug toxicities an increasingly crucial component of HIV. This study investigated the effects of adjuvant use of coconut oil and HAART on testicular morphology and seminal parameters in Sprague- Dawley rats. Twelve adult male Sprague-Dawley rats, weighing 153~169 g were distributed into four groups (A-D) and treated as follows: A served as control (distilled water); B (HAART cocktail- Zidovudine, Lamivudine and Nevirapine); C (HAART + Virgin coconut oil 10 mL/kg) and D (Virgin coconut oil 10 mL/kg)...
October 2016: Toxicological Research
https://www.readbyqxmd.com/read/27816052/postprandial-serum-endotoxin-in-healthy-humans-is-modulated-by-dietary-fat-in-a-randomized-controlled-cross-over-study
#13
Joshua M Lyte, Nicholas K Gabler, James H Hollis
BACKGROUND: High-fat diets may contribute to metabolic disease via postprandial changes in serum endotoxin and inflammation. It is unclear how dietary fat composition may alter these parameters. We hypothesized that a meal rich in n-3 (ω3) fatty acids would reduce endotoxemia and associated inflammation but a saturated or n-6 (ω6) fatty acid-rich meal would increase postprandial serum endotoxin concentrations and systemic inflammation in healthy adults. METHODS: Healthy adults (n = 20; mean age 25 ± 3...
November 5, 2016: Lipids in Health and Disease
https://www.readbyqxmd.com/read/27764914/the-effects-of-high-fat-diets-composed-of-different-animal-and-vegetable-fat-sources-on-the-health-status-and-tissue-lipid-profiles-of-male-japanese-quail-coturnix-coturnix-japonica
#14
Janine Donaldson, Michael Taurai Madziva, Kennedy Honey Erlwanger
Objective: The current study aimed to investigate the impact of high-fat diets composed of different animal and vegetable fat sources on serum metabolic health markers in Japanese quail, as well as the overall lipid content and fatty acid profiles of the edible bird tissues following significantly increased dietary lipid supplementation. Methods: Fifty seven male quail were divided into six groups and fed either a standard diet or a diet enriched with one of five different fats (22 % coconut oil, lard, palm oil, soybean oil or sunflower oil) for 12 weeks...
October 20, 2016: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/27756558/safety-assessment-of-widely-used-fermented-virgin-coconut-oil-cocos-nucifera-in-malaysia-chronic-toxicity-studies-and-sar-analysis-of-the-active-components
#15
Ahmad H Ibrahim, Md Shamsuddin Sultan Khan, Sawsan S Al-Rawi, Mohamed B Khadeer Ahamed, Aman Shah Bin Abdul Majid, Fouad Saleih R Al-Suede, Dan Ji, Amin Malik Shah Abdul Majid
Fermented Virgin Coconut Oil (FVCO) is widely used in the Southeast Asia as food and traditional medicine. The objective of the present study is the evaluation of chronic safety of the commercialized FVCO of Malaysia and other Southeast Asian countries. A single dose of 5000 mg/kg of FVCO was administered orally in rats (each group, n = 5) for the acute toxicity study and 175, 550 and 2000 mg/kg for sub-chronic and chronic studies (each group, n = 10), respectively. The behavior, mortality, and body weight of the rats were assessed to determine the toxic effects of FVCO...
November 2016: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/27756011/physical-stability-of-n-n-dimethyldecanamide-%C3%AE-pinene-in-water-emulsions-as-influenced-by-surfactant-concentration
#16
L A Trujillo-Cayado, M C Alfaro, M C García, J Muñoz
In recent years, interest in submicron emulsions has increased due to their high stability and potential applications in the encapsulation and release of active ingredients in many industrial fields, such as the food industry, pharmaceuticals or agrochemicals. Furthermore, the social demand for eco-friendly solutions to replace hazardous solvents in many dispersion formulations has steadily risen. In this study, the influence of surfactant concentration on the formation and physical stability of submicron oil-in-water emulsions using a high-pressure dual-channel homogenizer (microfluidizer) has been investigated...
January 1, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/27752194/coconut-oil-and-palm-oil-s-role-in-nutrition-health-and-national-development-a-review
#17
Laurene Boateng, Richard Ansong, William B Owusu, Matilda Steiner-Asiedu
: Coconut and palm oils which were the major sources of dietary fats for centuries in most of West Africa have been branded as unhealthy highly saturated fats. Their consumption has been peddled to supposedly raise the level of blood cholesterol, thereby increasing the risk of coronary heart disease. This adverse view has led to a reduction in their consumption in West Africa and they have been substituted for imported vegetable oils. Recent information however, indicates some beneficial effects of these oils particularly their roles in nutrition, health and national development...
September 2016: Ghana Medical Journal
https://www.readbyqxmd.com/read/27739293/dietary-fat-preference-and-effects-on-performance-of-piglets-at-weaning
#18
Ruey-Chee Weng
The objective of this experiment was to evaluate the interplay of dietary lipid sources and feeding regime in the transition from sow milk to solid food of abruptly weaned piglets. 144 weaned piglets were trained over a 15 day period to experience gradually reducing dietary fat content from 12% to 6% for lard (L), soybean oil (S) and coconut oil (C) and their feeding behavior and diet preference then tested in a behavior observation experiment. Another 324 weaned piglets were used in three consecutive feeding experiments to measure the effect of different dietary fats on performance and feed choice in the four weeks after abrupt weaning...
October 5, 2016: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/27719942/synthesis-of-medium-chain-length-capsinoids-from-coconut-oil-catalyzed-by-candida-rugosa-lipases
#19
Jovana Trbojević Ivić, Nenad Milosavić, Aleksandra Dimitrijević, Marija Gavrović Jankulović, Dejan Bezbradica, Dušan Kolarski, Dušan Veličković
A commercial preparation of Candida rugosa lipases (CRL) was tested for the production of capsinoids by esterification of vanillyl alcohol (VA) with free fatty acids (FA) and coconut oil (CO) as acyl donors. Screening of FA chain length indicated that C8-C12 FA (the most common FA found in CO triglycerides) are the best acyl-donors, yielding 80-85% of their specific capsinoids. Hence, when CO, which is rich in these FA, was used as the substrate, a mixture of capsinoids (vanillyl caprylate, vanillyl decanoate and vanillyl laurate) was obtained...
March 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27709654/coconut-oil-induced-production-of-a-surfactant-compatible-lipase-from-aspergillus-tamarii-under-submerged-fermentation
#20
Arijit Das, Sourav Bhattacharya, Srividya Shivakumar, Sujina Shakya, Swathi Shankar Sogane
Filamentous fungi are efficient producers of lipases. The present study focuses on identification of a potent lipolytic fungus and enhancement of lipase production through optimization of nutritional and cultural conditions under submerged fermentation. Molecular characterization of the fungus by 18S rDNA sequencing revealed its identity as Aspergillus tamarii with 98% homology. Maximum lipase production was noted in mineral salts medium supplemented with coconut oil (2.5%, v/v). A combination of ammonium chloride (2%, w/v) and tryptone (2%, w/v) facilitated maximum lipase production at pH 5 of the production medium...
October 6, 2016: Journal of Basic Microbiology
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