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https://www.readbyqxmd.com/read/29156154/coconut-phytocompounds-inhibits-polyol-pathway-enzymes-implication-in-prevention-of-microvascular-diabetic-complications
#1
Devi Lekshmi Sheela, Puthiyaveetil Abdulla Nazeem, Arunaksharan Narayanankutty, R Muthangaparambil Shylaja, Sangeetha P Davis, Priyanga James, Ravisankar Valsalan, Thekkekara Devassy Babu, Achuthan C Raghavamenon
Coconut oil (CO), the primary choice of cooking purposes in the south Asian countries, is rich in medium chain saturated fatty acids, especially lauric acid (50-52%). The oil has high medicinal use in Ayurvedic system and known to contain polyphenolic antioxidants. Studies have reported that CO improves insulin sensitivity and shows hypoglycemic effect. However, there is no information regarding its effect on chronic diabetic complications including retinopathy and nephropathy is available. The secondary diabetic complications are mediated by the activation of polyol pathway, where aldose reductase (AR) plays crucial role...
December 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/29151890/techno-economic-and-resource-analysis-of-hydroprocessed-renewable-jet-fuel
#2
Ling Tao, Anelia Milbrandt, Yanan Zhang, Wei-Cheng Wang
Background: Biomass-derived jet fuel is an alternative jet fuel (AJF) showing promise of reducing the dependence on fossil fuel and greenhouse gas emissions. Hydroprocessed esters and fatty acids (HEFA) concept is also known as one of the pathways for producing bio jet fuel. HEFA fuel was approved by the American Society for Testing and Materials in 2011, and can be blended up to 50% with conventional jet fuel. Since then, several HEFA economic and life-cycle assessments have been published in literature...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/29128745/a-new-method-for-determination-of-cocamidopropyl-betaine-synthesized-from-coconut-oil-through-spectral-shift-of-eriochrome-black-t
#3
Ali Gholami, Mahshid Golestaneh, Zeinab Andalib
Cocamidopropyl betaine (CAPB) is a zwitterionic surfactant that is synthesized using coconut oil and usually supplied in form of an aqueous solution with 25-37% w/w. In this study, a novel method based on UV-visible spectroscopy is developed for an accurate determination of CAPB synthesized from coconut oil. Eriochrome Black T (EBT) as a specific color indicator was added to CAPB and a red shift and color change were observed. This shift leads in increasing wavelength selectivity of the method. The change in the color intensity depends on the concentration of CAPB...
November 9, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29118979/the-effects-of-starter-microbiota-and-the-early-life-feeding-of-medium-chain-triglycerides-on-the-gastric-transcriptome-profile-of-2-or-3-week-old-cesarean-delivered-piglets
#4
Paolo Trevisi, Davide Priori, Vincenzo Motta, Diana Luise, Alfons J M Jansman, Sietse-Jan Koopmans, Paolo Bosi
Background: The stomach is an underestimated key interface between the ingesta and the digestive system, affecting the digestion and playing an important role in several endocrine functions. The quality of starter microbiota and the early life feeding of medium chain triglycerides may affect porcine gastric maturation. Two trials (T1, T2) were carried out on 12 and 24 cesarean-delivered piglets (birth, d0), divided over two microbiota treatments, but slaughtered and sampled at two or three weeks of age, respectively...
2017: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/29081890/role-of-diet-and-nutritional-supplements-in-parkinson-s-disease-progression
#5
Laurie K Mischley, Richard C Lau, Rachel D Bennett
OBJECTIVES: The goal of this study is to describe modifiable lifestyle variables associated with reduced rate of Parkinson's disease (PD) progression. METHODS: The patient-reported outcomes in PD (PRO-PD) were used as the primary outcome measure, and a food frequency questionnaire (FFQ) was used to assess dietary intake. In this cross-sectional analysis, regression analysis was performed on baseline data to identify the nutritional and pharmacological interventions associated with the rate of PD progression...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29071233/effect-of-addition-of-antifungal-agents-on-physical-and-biological-properties-of-a-tissue-conditioner-an-in-vitro-study
#6
Pragati Rawat, Swatantra Agarwal, Siddhi Tripathi
Purpose: Tissue conditioners are used for healing of abused oral tissues. They may harbour microorganisms causing oral diseases such as candidiasis compromising the health of the patient. Also, addition of antifungal agents into tissue conditioner may alter its properties. This study compares the anti-fungal property and mechanical properties of tissue conditioner containing different antifungal agents. Methods: Three antifungal agents, one synthetic - fluconazole, and two natural - oregano oil and virgin coconut oil were added into the tissue conditioner (Viscogel) in different concentrations...
September 2017: Advanced Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/29051664/status-of-the-bioactive-phytoceuticals-during-deep-fat-frying-of-snack-food-using-nutra-coconut-oil
#7
M Maneesh Kumar, Sheema Faiza, Sukumar Debnath, Nasirullah
The present study was carried out to study the physico-chemical changes that take place in both product and oil during the deep fat frying of a traditional savoury snack 'kodubale', at 120-160 °C for 120-600 s using coconut oil (CO) and nutra-coconut oil (NCO). Further, kinetic studies on moisture loss, oil uptake, color and degradation of β-carotene, total polyphenol content and antioxidant activity for kodubale was carried out during frying as a function of temperature and time. The study showed that the kinetic coefficients for above parameters increased with temperature and time and the data obtained were well fitted with first order kinetic model...
October 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29048487/the-genome-draft-of-coconut-cocos-nucifera
#8
Yong Xiao, Pengwei Xu, Haikuo Fan, Luc Baudouin, Wei Xia, Stéphanie Bocs, Junyang Xu, Qiong Li, Anping Guo, Lixia Zhou, Jing Li, Yi Wu, Zilong Ma, Alix Armero, Auguste Emmanuel Issali, Na Liu, Ming Peng, Yaodong Yang
Coconut palm (Cocos nucifera,2n = 32), a member of genus Cocos and family Arecaceae (Palmaceae), is an important tropical fruit and oil crop. Currently, coconut palm is cultivated in 93 countries, including Central and South America, East and West Africa, Southeast Asia and the Pacific Islands, with a total growth area of more than 12 million hectares [1]. Coconut palm is generally classified into 2 main categories: "Tall" (flowering 8-10 years after planting) and "Dwarf" (flowering 4-6 years after planting), based on morphological characteristics and breeding habits...
November 1, 2017: GigaScience
https://www.readbyqxmd.com/read/28958541/physicochemical-and-functional-properties-of-protein-concentrate-from-by-product-of-coconut-processing
#9
Pattrathip Rodsamran, Rungsinee Sothornvit
Coconut cake, a by-product from milk and oil extractions, contains a high amount of protein. Protein extraction from coconut milk cake and coconut oil cake was investigated. The supernatant and precipitate protein powders from both coconut milk and oil cakes were compared based on their physicochemical and functional properties. Glutelin was the predominant protein fraction in both coconut cakes. Protein powders from milk cake presented higher water and oil absorption capacities than those from oil cake. Both protein powders from oil cake exhibited better foaming capacity and a better emulsifying activity index than those from milk cake...
February 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28952512/ereptiospiration
#10
Christine Woolley, Antonio A Garcia, Marco Santello
Pure coconut oil, lanolin, and acetaminophen were vaporized at rates of 1-50 mg/min, using a porous network exhibiting a temperature gradient from 5000 to 5500 K/mm, without incurring noticeable chemical changes due to combustion, oxidation, or other thermally-induced chemical structural changes. The newly coined term "ereptiospiration" is used here to describe this combination of thermal transpiration at high temperature gradients since the process can force the creation of thermal aerosols by rapid heating in a localized zone...
April 12, 2017: Bioengineering
https://www.readbyqxmd.com/read/28932063/-castor-oil-the-culprit-of-acute-hair-felting
#11
V Ramya Maduri, Ahalya Vedachalam, S Kiruthika
Acute hair felting is a rare disorder of scalp hair. In this condition, the hair becomes twisted, entangled as a hard stony mass resembling a bird's nest. Sudden hair matting has been reported earlier in the literature after vigorous use of chemical and herbal shampoos. Plica polonica is a patchy area of hair matting occurring in due course of time in neglected hair or underlying psychiatric illness. This case is interesting as the whole scalp hair matted immediately after using coconut oil and castor oil following washing...
July 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/28924490/the-lauric-acid-activated-signaling-prompts-apoptosis-in-cancer-cells
#12
Rosamaria Lappano, Anna Sebastiani, Francesca Cirillo, Damiano Cosimo Rigiracciolo, Giulia Raffaella Galli, Rosita Curcio, Roberta Malaguarnera, Antonino Belfiore, Anna Rita Cappello, Marcello Maggiolini
The saturated medium-chain fatty-acid lauric acid (LA) has been associated to certain health-promoting benefits of coconut oil intake, including the improvement of the quality of life in breast cancer patients during chemotherapy. As it concerns the potential to hamper tumor growth, LA was shown to elicit inhibitory effects only in colon cancer cells. Here, we provide novel insights regarding the molecular mechanisms through which LA triggers antiproliferative and pro-apoptotic effects in both breast and endometrial cancer cells...
2017: Cell Death Discovery
https://www.readbyqxmd.com/read/28895890/skin-penetration-enhancement-by-natural-oils-for-dihydroquercetin-delivery
#13
Vytis Čižinauskas, Nicolas Elie, Alain Brunelle, Vitalis Briedis
Natural oils are commonly used in topical pharmaceutical formulations as emulsifiers, stabilizers or solubility enhancers. They are presented as safe and inert components, mainly used for formulation purposes. It is confirmed that natural oils can affect the skin penetration of various substances. Fatty acids are mainly responsible for this effect. Current understanding lacks reliable scientific data on penetration of natural oils into the skin and their skin penetration enhancement potential. In the current study, fatty acid content analysis was used to determine the principal fatty acids in soybean, olive, avocado, sea-buckthorn pulp, raspberry seed and coconut oils...
September 12, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28862329/virgin-coconut-oil-reverses-hepatic-steatosis-by-restoring-redox-homeostasis-and-lipid-metabolism-in-male-wistar-rats
#14
Arunaksharan Narayanankutty, Devika Mukundan Palliyil, Kezia Kuruvilla, Achuthan C Raghavamenon
BACKGROUND: Hepatosteatosis, a form of nonalcoholic fatty liver disease (NAFLD), is being increasingly recognized as a major health burden worldwide. Insulin resistance, dyslipidemia and imbalances in adipokine/cytokine interplay are reported to be involved in the onset and progression of this disease. Use of dietary nutraceuticals in prevention and treatment of NAFLD is emerging. Virgin coconut oil (VCO), a fermented product of fresh coconut kernel, has been shown to impede the development of hepatosteatosis in rats...
September 1, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28816548/dietary-supplementation-with-virgin-coconut-oil-improves-lipid-profile-and-hepatic-antioxidant-status-and-has-potential-benefits-on-cardiovascular-risk-indices-in-normal-rats
#15
Ademola C Famurewa, Chima A Ekeleme-Egedigwe, Sophia C Nwali, Ngozi N Agbo, Joy N Obi, Goodness C Ezechukwu
Research findings that suggest beneficial health effects of dietary supplementation with virgin coconut oil (VCO) are limited in the published literature. This study investigated the in vivo effects of a 5-week VCO-supplemented diet on lipid profile, hepatic antioxidant status, hepatorenal function, and cardiovascular risk indices in normal rats. Rats were randomly divided into 3 groups: 1 control and 2 treatment groups (10% and 15% VCO-supplemented diets) for 5 weeks. Serum and homogenate samples were used to analyze lipid profile, hepatorenal function markers, hepatic activities of antioxidant enzymes, and malondialdehyde level...
August 17, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28805896/the-composition-of-dietary-fat-alters-the-transcriptional-profile-of-pathways-associated-with-lipid-metabolism-in-the-liver-and-adipose-tissue-in-the-pig
#16
T A Kellner, N K Gabler, J F Patience
The objective was to investigate the of effect chemical composition of dietary fat on transcription of genes involved in lipid metabolism in adipose tissue and the liver via transcriptional profiling in growing pigs. A total of 48 Genetiporc 6.0 × Genetiporc F25 (PIC, Inc., Hendersonville, TN) barrows (initial BW of 44.1 ± 1.2 kg) were randomly allotted to 1 of 6 dietary treatments. Each experimental diet included 95% of a corn-soybean meal basal diet and 5% cornstarch (control; CNTR), animal-vegetable blend (AV), coconut oil (COCO), corn oil (COIL), fish oil (FO), or tallow (TAL)...
August 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28794308/characterization-of-coconut-oil-fractions-obtained-from-solvent-fractionation-using-acetone
#17
Sopark Sonwai, Poonyawee Rungprasertphol, Nantinee Nantipipat, Satinee Tungvongcharoan, Nantikan Laiyangkoon
This work was aimed to study the solvent fraction of coconut oil (CNO). The fatty acid and triacylglycerol compositions, solid fat content (SFC) and the crystallization properties of CNO and its solid and liquid fractions obtained from fractionation at different conditions were investigated using various techniques. CNO was dissolved in acetone (1:1 w/v) and left to crystallize isothermally at 10℃ for 0.5, 1 and 2 h and at 12°C for 2, 3 and 6 h. The solid fractions contained significantly lower contents of saturated fatty acids of ≤ 10 carbon atoms but considerably higher contents of saturated fatty acids with > 12 carbon atoms with respect to those of CNO and the liquid fractions...
August 8, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28777952/influence-of-fat-and-oil-type-on-the-yield-physico-chemical-properties-and-microstructure-of-fat-oil-and-grease-fog-deposits
#18
Dann Marie N Del Mundo, Manote Sutheerawattananonda
Fat, oil, and grease (FOG) deposit, in the form of calcium soap, was found to cause sanitary sewer overflows due to its adhesion on pipe walls. To address this problem, laboratory-prepared calcium soaps have been used to investigate the formation mechanisms of FOG deposits. However, the fats and oils previously utilized were limited and some soap characteristics were not examined. This research attempted to probe through the properties of calcium soaps prepared from calcium chloride and the fats and oils of chicken, pork, palm olein, soybean, olive, and coconut to further understand FOG formation and stability...
November 1, 2017: Water Research
https://www.readbyqxmd.com/read/28758166/a-coconut-oil-rich-meal-does-not-enhance-thermogenesis-compared-to-corn-oil-in-a-randomized-trial-in-obese-adolescents
#19
Janna LaBarrie, Marie-Pierre St-Onge
BACKGROUND: Consumption of medium chain triglycerides (MCT) in overweight adults increases thermogenesis and improves weight management. Coconut oil is a rich natural source of MCT, but its thermogenic effect is unknown. Our study evaluated the effects of a test oil enriched in coconut oil, on energy expenditure, satiety, and metabolic markers in a randomized, double blind, cross-over study. METHODS AND FINDINGS: Fifteen children, age 13-18 years, body mass index >85th percentile for age and sex, were enrolled...
2017: Insights Nutr Metab
https://www.readbyqxmd.com/read/28756564/production-of-dodecanedioic-acid-via-biotransformation-of-low-cost-plant-oil-derivatives-using-candida-tropicalis
#20
Irina Funk, Nina Rimmel, Christoph Schorsch, Volker Sieber, Jochen Schmid
Dodecanedioic acid (DDA) is highly useful to the chemical industry as a versatile precursor for producing the polyamide nylon-6,12, which is used for many technical applications, such as heat and chemical-resistant sheaths. However, DDA synthesis has several drawbacks, such as high energy input and cost-intensive removal of by-products. Therefore, alternative bio-based production routes are required due to increasing industrial demand for green chemicals and renewable products. Candida tropicalis converts petrochemical-based n-dodecanes to the corresponding dicarboxylic acids by targeted functionalization...
July 29, 2017: Journal of Industrial Microbiology & Biotechnology
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