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Filariasis , diagnosis

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https://www.readbyqxmd.com/read/27867674/filariasis-of-stensen-s-duct-an-index-case
#1
Eishaan K Bhargava, Nikhil Arora, Varun Rai, Ravi Meher, Prerna Arora, Ruchika Juneja
Filariasis, a neglected tropical disease, is a global health problem and is endemic to 73 countries including India. It is caused by nematodes of Filariodidea family, namely, W. bancrofti and B. malayi in India, which have a predilection for the lower limbs and testis. We report a never before reported case of filariasis of the main parotid duct in a 25-year-old male that resolved on medical management, exemplifying the importance of maintaining a high index of suspicion and careful examination of cytological smears in endemic countries, allowing for an early diagnosis and treatment, decreasing the morbidity of this debilitating disease...
2016: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/27729568/positivity-of-antigen-tests-used-for-diagnosis-of-lymphatic-filariasis-in-individuals-without-wuchereria-bancrofti-infection-but-with-high-loa-loa-microfilaremia
#2
Sébastien D Pion, Céline Montavon, Cédric B Chesnais, Joseph Kamgno, Samuel Wanji, Amy D Klion, Thomas B Nutman, Michel Boussinesq
Since the mid-2000s, the immunochromatographic card test (ICT), a point-of-care test for detecting Wuchereria bancrofti circulating filarial antigens (CFAs), has been the backbone for mapping and monitoring lymphatic filariasis (LF) worldwide. Recently, there have been instances in which CFA positivity has been associated with Loa loa microfilaremia. Here, we examined the association, at both the community and individual levels, between L. loa and CFA using additional diagnostic tools (quantitative polymerase chain reaction [qPCR], Og4C3 enzyme-linked immunosorbent assay, and IgG4 antibodies to Wb123 assays) to demonstrate the relationship between L...
October 10, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27474244/-screening-of-parasitic-diseases-in-the-asymptomatic-immigrant-population
#3
Lidia Goterris, Cristina Bocanegra, Núria Serre-Delcor, Zaira Moure, Begoña Treviño, Francesc Zarzuela, Mateu Espasa, Elena Sulleiro
Parasitic diseases suppose an important health problem in people from high endemic areas, so these must be discarded properly. Usually, these infections develop asymptomatically but, in propitious situations, are likely to reactivate themselves and can cause clinical symptoms and/or complications in the receiving country. Moreover, in some cases it is possible local transmission. Early diagnosis of these parasitic diseases made by appropriate parasitological techniques and its specific treatment will benefit both, the individual and the community...
July 2016: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/27413335/adult-filarial-worm-from-the-breast-aspirate-of-a-young-man
#4
Hilda Fernandes, Beena Mary Thomas, Indira Putran
Microfilariae and adult filarial worm have been incidentally detected in fine needle aspirates of various lesions in clinically unsuspected cases. Here we report a male patient who presented with a tender breast nodule and single enlarged lymph node. Fine Needle Aspiration (FNA) yielded 1 ml of yellow coloured fluid and single thread like worm measuring 6 × 0.2 cm. A diagnosis of breast abscess with a worm morphologically consistent with filariasis was offered. A follow up visit after 2 months showed regression of the breast lesion and the lymph node...
June 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27313932/a-rare-case-of-ovarian-filariasis-in-abidjan
#5
Doukouré Brahima, Abouna Alain Didier, Dou Gonat Serge Pacôme, Aman Nguiessan Alphonse, Koffi Abdoul, Diomandé Mohenou Isidore Jean-Marie
Ovarian filariasis is an exceptional disease and displays a major diagnostic problem even in endemic areas. We reported the case of a 19-year-old patient who had ovarian cyst which was revealed by chronic pelvic pain. The histological examination of oophorectomy specimen led to the Wuchereria bancrofti filariasis of the ovary. The anatomopathologic examination is required for the diagnosis of this disease.
2016: Case Reports in Pathology
https://www.readbyqxmd.com/read/27182151/microfilarial-involvement-of-the-neck-region-a-case-report-and-review-of-literature
#6
Varun Kumar Singh, Abhishek Kashyap, Harekrushna Sahu, Geetika Khanna, Vinay Prabhat
INTRODUCTION: Filariasis is caused by parasitic infections, most commonly Brugia malayi and Wuchereria bancrofti. India is one of the endemic countries for such disease. The usually involved organs are lower limbs and external genitalia. Neck region is rarely involved and only a few cases have been reported in literature. CASE REPORT: We reported such a case where filarial involvement has involved the neck region and reached up to the level of upper cervical vertebra...
April 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/27159510/ocular-filariasis-in-us-residents-returning-travelers-and-expatriates
#7
James H Diaz
Several factors acting in concert now place US residents, returning travelers, and expatriates at risks of contracting ocular filariasis including increasing seroprevalence rates of zoonotic filariasis, international travel bringing tourists to and expatriates from filariasis-endemic regions, and warming temperatures extending distribution ranges of arthropod vectors. To describe the epidemiology and outcomes of ocular filariasis and to recommend strategies for the diagnosis, management, and prevention of ocular filariasis, internet search engines were queried with the key words in order to examine case reports and series of ocular filariasis in the US and elsewhere...
July 2015: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/27138537/ocular-filariasis-in-us-residents-returning-travelers-and-expatriates
#8
James H Diaz
Several factors acting in concert now place US residents, returning travelers, and expatriates at risks of contracting ocular filariasis including increasing seroprevalence rates of zoonotic filariasis, international travel bringing tourists to and expatriates from filariasis-endemic regions, and warming temperatures extending distribution ranges of arthropod vectors. To describe the epidemiology and outcomes of ocular filariasis and to recommend strategies for the diagnosis, management, and prevention of ocular filariasis, internet search engines were queried with the key words in order to examine case reports and series of ocular filariasis in the US and elsewhere...
July 2015: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/27130361/-filarial-dance-sign-real-time-ultrasound-diagnosis-of-filarial-oophoritis
#9
Surekha Panditi, Ashwini G Shelke, Laxmi Narasimha Praveen Thummalakunta
Filariasis is a parasitic disease caused by Filarial nematodes (Wuchereria bancrofti, Brugia malayi, and Brugia timori) that commonly causes lymphatic obstruction resulting in edema and increase in the size of the affected organ. Filariasis is diagnosed by identifying microfilariae on Giemsa stain. The immunochromatographic card test is diagnostic. Ultrasound is the imaging modality of choice for detecting adult filarial worms/microfilaria in the lymphatic system, which are responsible for the classic "filarial dance sign" caused by twirling movements of the microfilariae...
October 2016: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/27085707/detection-and-quantification-of-wuchereria-bancrofti-and-brugia-malayi-dna-in-blood-samples-and-mosquitoes-using-duplex-droplet-digital-polymerase-chain-reaction
#10
Jurairat Jongthawin, Pewpan M Intapan, Viraphong Lulitanond, Oranuch Sanpool, Tongjit Thanchomnang, Lakkhana Sadaow, Wanchai Maleewong
Lymphatic filariasis, a mosquito-borne disease, is still a major public health problem in tropical and sub-tropical countries. Effective diagnostic tools are required for identification of infected individuals, for epidemiological assessment, and for monitoring of control programs. A duplex droplet digital polymerase chain reaction (ddPCR) was conducted to differentiate and quantify Wuchereria bancrofti DNA by targeting the long DNA repeat (LDR) element and Brugia malayi DNA by targeting the HhaI element in blood samples and mosquito vectors...
August 2016: Parasitology Research
https://www.readbyqxmd.com/read/27011444/unusual-presentation-of-filariasis-as-an-abscess-a-case-report
#11
Mukta Ahuja, Sonam Kumar Pruthi, Renu Gupta, Pratima Khare
Bancroftian filariasis, a tropical and subtropical disease caused by Wuchereria bancrofti, is transmitted by the culex mosquito. The disease is conventionally diagnosed by the demonstration of microfilaria in peripheral blood smear. Microfilaria and adult filarial worms have been incidentally detected in fine needle aspiration cytology (FNAC) in various locations. The disease may be missed if one is not aware of the possibility, particularly in cases where eosinophilia is absent. Therefore, clinicians and pathologists need to be more vigilant in the endemic zones for early diagnosis and the treatment of filariasis...
January 2016: Journal of Cytology
https://www.readbyqxmd.com/read/26879053/diagnosis-of-a-malayan-filariasis-case-using-a-shotgun-diagnostic-metagenomics-assay
#12
Dian Gao, Qiongfang Yu, Guangqiang Wang, Guitang Wang, Fan Xiong
BACKGROUND: Malayan filariasis is a lymphatic filariasis caused by Brugia malayi. It is easily misdiagnosed in non-endemic areas for atypical symptoms and rare diagnostic experience. A 34-year-old Chinese woman in New York presented with diffuse erythema on her body, swelling of her body, and watery, itchy, red, sore, swollen and stinging of the eyes, and severe night-time itching. No hospital that the patient visited could make a definite diagnosis by conventional diagnostic methods...
2016: Parasites & Vectors
https://www.readbyqxmd.com/read/26700472/loss-of-sensitivity-of-immunochromatographic-test-ict-for-lymphatic-filariasis-diagnosis-in-low-prevalence-settings-consequence-in-the-monitoring-and-evaluation-procedures
#13
Raceline Gounoue-Kamkumo, Hugues C Nana-Djeunga, Jean Bopda, Julie Akame, Ann Tarini, Joseph Kamgno
BACKGROUND: Diagnostic tools for lymphatic filariasis (LF) elimination programs are useful in mapping the distribution of the disease, delineating areas where mass drug administrations (MDA) are required, and determining when to stop MDA. The prevalence and burden of LF have been drastically reduced following mass treatments, and the evaluation of the performance of circulating filarial antigen (CFA)-based assays was acknowledged to be of high interest in areas with low residual LF endemicity rates after multiple rounds of MDA...
2015: BMC Infectious Diseases
https://www.readbyqxmd.com/read/26646772/circulating-filarial-antigen-detection-in-brugian-filariasis
#14
Praveen Kumar Tripathi, Ramesh Chander Mahajan, Nancy Malla, Abhishek Mewara, Shailja Misra Bhattacharya, Ranganatha Krishna Shenoy, Rakesh Sehgal
Human lymphatic filariasis (LF) is a major cause of disability globally. The success of global elimination programmes for LF depends upon effectiveness of tools for diagnosis and treatment. In this study on stage-specific antigen detection in brugian filariasis, L3, adult worm (AW) and microfilarial antigenaemia were detected in around 90-95% of microfilariae carriers (MF group), 50-70% of adenolymphangitis (ADL) patients, 10-25% of chronic pathology (CP) patients and 10-15% of endemic normal (EN) controls...
March 2016: Parasitology
https://www.readbyqxmd.com/read/26634138/cytological-diagnosis-of-bancroftian-filariasis-presented-as-a-subcutaneous-swelling-in-the-cubital-fossa-an-unusual-presentation
#15
Pinki Pandey, Alok Dixit, Subrat Chandra, Aparna Tanwar
Filariasis is a disabling parasitic disease and the prevalence of lymphatic filariasis caused by Wuchereria bancrofti is quite high in India. However, W. bancrofti presenting as a subcutaneous swelling and a demonstration of microfilariae in cytological smears from upper extremity lesions is extremely rare. We report a case of 20-year-old male who presented with a small subcutaneous swelling near medial aspect of the left cubital fossa. The wet mount preparation showed many motile microfilariae. Cytology smears revealed a large number of sheathed microfilariae with the tail tip free of nucleus, identified as W...
April 2015: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/26568337/mucocutaneous-manifestations-of-helminth-infections-nematodes
#16
REVIEW
Omar Lupi, Christopher Downing, Michael Lee, Livia Pino, Francisco Bravo, Patricia Giglio, Aisha Sethi, Sidney Klaus, Omar P Sangueza, Claire Fuller, Natalia Mendoza, Barry Ladizinski, Laila Woc-Colburn, Stephen K Tyring
In the 21st century, despite increased globalization through international travel for business, medical volunteerism, pleasure, and immigration/refugees into the United States, there is little published in the dermatology literature regarding the cutaneous manifestations of helminth infections. Approximately 17% of travelers seek medical care because of cutaneous disorders, many related to infectious etiologies. This review will focus on the cutaneous manifestations of helminth infections and is divided into 2 parts: part I focuses on nematode infections, and part II focuses on trematode and cestode infections...
December 2015: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/26416111/point-of-care-ultrasound-assessment-of-tropical-infectious-diseases-a-review-of-applications-and-perspectives
#17
REVIEW
Sabine Bélard, Francesca Tamarozzi, Amaya L Bustinduy, Claudia Wallrauch, Martin P Grobusch, Walter Kuhn, Enrico Brunetti, Elizabeth Joekes, Tom Heller
The development of good quality and affordable ultrasound machines has led to the establishment and implementation of numerous point-of-care ultrasound (POCUS) protocols in various medical disciplines. POCUS for major infectious diseases endemic in tropical regions has received less attention, despite its likely even more pronounced benefit for populations with limited access to imaging infrastructure. Focused assessment with sonography for HIV-associated TB (FASH) and echinococcosis (FASE) are the only two POCUS protocols for tropical infectious diseases, which have been formally investigated and which have been implemented in routine patient care today...
January 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/26273808/rapid-differentiation-of-filariae-in-unstained-and-stained-paraffin-embedded-sections-by-a-high-resolution-melting-analysis-pcr-assay
#18
Sirichit Wongkamchai, Benjaporn Mayoon, Namthip Kanakul, Suporn Foongladda, Darawan Wanachiwanawin, Hathai Nochote, Sumart Loymek
BACKGROUND: Apart from infection with human filariae, zoonotic filariasis also occurs worldwide, and the numbers of cases have been increasing steadily. Diagnosis of intact filariae in tissues or organs depends on histological identification. The morphology of parasites in tissue-embedded sections is poor and shows high levels of homoplasy. Thus, the use of morphological characteristics in taxonomic studies is difficult and may not allow a specific diagnosis. METHODS: Here we report the use of real-time PCR with high-resolution melting analysis (HRM) to detect and identify Brugia malayi, Brugia pahangi, Wuchereria bancrofti, and Dirofilaria immitis in paraffin-embedded sections...
August 2015: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/26240733/recurrent-hemorrhagic-pericardial-effusion-and-tamponade-due-to-filariasis-successfully-treated-with-ivermectin-and-albendazole
#19
Santosh Kumar Sinha, Amit Goel, Mohit Sachan, Sameer Saraf, Chandra Mohan Verma
Filariasis presenting with pericardial effusion with tamponade is rare. We report a case of a 30-year-old female who was admitted with severe dyspnea and chest pain since 2 days. Echocardiogram showed massive pericardial effusion with tamponade. Pericardial fluid aspiration drained 1.2 L of hemorrhagic fluid. Cytology examination revealed microfilaria of Wuchereria bancrofti. She was treated with diethyl carbamazine and discharged. Six weeks later, she presented again with massive pericardial effusion with cardiac tamponade...
April 2015: Heart Views: the Official Journal of the Gulf Heart Association
https://www.readbyqxmd.com/read/26119541/epidemiology-of-elephantiasis-with-special-emphasis-on-podoconiosis-in-ethiopia-a-literature-review
#20
REVIEW
Mulat Yimer, Tadesse Hailu, Wondemagegn Mulu, Bayeh Abera
Elephantiasis is a symptom of a variety of diseases that is characterized by the thickening of the skin and underlying tissues, especially in the legs, male genitals and female breasts. Some conditions having this symptom include: Elephantiasis nostras, due to longstanding chronic lymphangitis; Elephantiasis tropica or lymphatic filariasis, caused by a number of parasitic worms, particularly Wuchereria bancrofti; non-filarial elephantiasis or podoconiosis, an immune disease caused by heavy metals affecting the lymph vessels; proteus syndrome, the genetic disorder of the so-called Elephant Man, etc...
June 2015: Journal of Vector Borne Diseases
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