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Dermal Implants

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https://www.readbyqxmd.com/read/29897162/in-vivo-biocompatibility-and-time-dependent-changes-in-mechanical-properties-of-woven-collagen-meshes-a-comparison-to-xenograft-and-synthetic-mid-urethral-sling-materials
#1
Katherine Chapin, Ahmad Khalifa, Thomas Mbimba, Phillip McClellan, James Anderson, Yuri Novitsky, Adonis Hijaz, Ozan Akkus
Meshes woven from highly aligned collagen threads crosslinked using either genipin or 1-ethyl-3-(3-dimethylaminopropyl) carboiimide and N-hydroxy succinimide (EDC/NHS) were implanted in a subcutaneous rat model to evaluate their biocompatibility (at 2 weeks, 2 months, and 5 months), mechanical properties (at baseline, 2 months, and 5 months) and ultimately their suitability for use as mid-urethral slings (MUS) for management of stress urinary incontinence. Porcine dermal (Xenmatrix) and monofilament polypropylene (Prolene) meshes were also implanted to provide comparison to clinically used materials...
June 13, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29878997/novel-approach-for-risk-reducing-mastectomy-first-stage-implant-placement-and-subsequent-second-stage-mastectomy
#2
Geok- Hoon Lim, Andrew Baildam
BACKGROUND: Risk-reducing mastectomy (RRM) with tissue expander then implant-based breast reconstruction conventionally involved immediate submuscular placement of tissue expanders during mastectomy, then after expansion, replacement of expanders for permanent implants in a second stage operation. Use of acellular dermal matrix (ADM) can achieve a single staged operation but ADMs are costly and may have potential complications. We aim to assess the feasibility of placement of implants as a first stage before RRM as a novel technique of reconstruction which avoids the need for serial outpatient expansion and ADM...
June 2, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29878993/human-acellular-dermis-as-spacer-for-small-joint-arthroplasty-analysis-of-revascularization-in-a-rabbit-trapeziectomy-model
#3
Kian Banks, Lee Squiteri, Athanasios Bramos, Maxwell B Johnson, Daniel J Gardner, Austin Pourmoussa, Eunson Jung, Gene Lee, David Perrault, Alexander Fedenko, Gene H Kim, Bo Han, Young-Kwon Hong, David A Kulber, Alex K Wong
BACKGROUND: Carpometacarpal (CMC) osteoarthritis affects 8-12% of the general population. Surgical management provides symptomatic relief for 78% of patients who fail conservative therapy, but little consensus exists regarding which surgical procedure provides superior patient outcomes. Recent human trials substituted exogenous acellular dermal matrices (ADMs) in the bone space, but there is no quantitative histological data on the outcome of ADMs in this environment. We aimed to quantify the revascularization and recellularization of ADMs in the joint space using a rabbit model...
June 5, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29876243/endoscopic-gluteus-medius-and-minimus-repair-with-allograft-augmentation-using-acellular-human-dermis
#4
Jovan Laskovski, Ryan Urchek
Recently, attention has been given to recalcitrant lateral hip pain, also known as greater trochanteric pain syndrome. Although, historically, this has been attributed to greater trochanteric bursitis, the literature has shown that many patients will have a lesion of the gluteus medius and minimus tendons. Endoscopic hip abductor tendon repair has been shown to provide good outcomes with decreasing overall morbidity and is becoming more popular. However, failure rates have been reported to be as high as 35%, likely due to the poor tissue quality in this older population...
March 2018: Arthroscopy Techniques
https://www.readbyqxmd.com/read/29876185/technique-refinement-in-prepectoral-implant-breast-reconstruction-with-vicryl-mesh-pocket-and-acellular-dermal-matrix-support
#5
Lisa Gfrerer, Eric C Liao
Direct-to-implant reconstruction after mastectomy is routinely performed with excellent oncologic and aesthetic outcomes. Several different techniques for placement of the prosthesis including total and partial subpectoral coverage have been described. Prepectoral implant placement is increasingly reported as a safe method, while patient selection and techniques are areas of further work. Most prepectoral prosthesis placement techniques describe complete acellular dermal matrix (ADM) coverage of the implant, often requiring multiple or larger ADM sheets than a comparable subpectoral implant procedure, resulting in high cost per reconstructed breast...
April 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29876184/goldilocks-mastectomy-with-bilateral-in-situ-nipple-preservation-via-dermal-pedicle
#6
Heather Richardson, Joel A Aronowitz
Patients who don't want or can't have formal breast reconstruction after mastectomy surgery can be considered for a Goldilocks mastectomy, where the breast fullness is recreated from what is left behind after the gland tissue is removed from underneath the skin in a breast reduction pattern. A Goldilocks mastectomy does not require the use of implants or tissue transfer from other parts of the body and may be completed in a single surgery. This is best suited for larger breasted women who are willing to have much smaller breasts as a result...
April 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29876165/prepectoral-breast-reconstruction-with-fenestrated-acellular-dermal-matrix-a-novel-design
#7
Keyianoosh Z Paydar, Garrett A Wirth, Donald S Mowlds
Fenestrated acellular dermal matrix (ADM) has improved patient outcomes in both direct-to-implant and 2-stage tissue expander/implant breast reconstruction. This technical alteration utilizes optimal fenestration overlap to enhance the breast reconstruction experience. We present a novel, surgeon-designed shaped fenestrated ADM, placed in the recently repopularized prepectoral pocket for anterior coverage of implants in direct-to-implant and 2-stage breast reconstruction. A retrospective review of 10 patients (18 breasts) who underwent direct-to-implant or 2-stage breast reconstruction utilizing fenestrated shaped ADM in the prepectoral plane at a major academic institution in 2016 was conducted...
April 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29874964/tigr-%C3%A2-matrix-surgical-mesh-a-two-year-follow-up-study-and-complication-analysis-in-65-immediate-breast-reconstructions
#8
Håkan Hallberg, Richard Lewin, Anna Elander, Emma Hansson
In recent years, it has become increasingly popular to use matrices, such as acellular dermal matrices, in implant-based breast reconstruction. To lower the cost and to avoid implanting biological material, the use of synthetic meshes has been proposed. This is the first study examining TIGR® Mesh in a larger series of immediate breast reconstruction. The aims of the study were to examine complications and predictors for complications. All consecutive patients operated on with breast reconstruction with TIGR® Matrix Surgical Mesh and tissue expanders (TEs) or permanent implant between March 2015 and September 2016 in our department were prospectively included...
June 7, 2018: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/29870447/preoperative-doxycycline-does-not-reduce-propionibacterium-acnes-in-shoulder-arthroplasty
#9
Allison J Rao, Peter N Chalmers, Gregory L Cvetanovich, Michael C O'Brien, Jon M Newgren, Brian J Cole, Nikhil N Verma, Gregory P Nicholson, Anthony A Romeo
BACKGROUND: Propionibacterium acnes (P. acnes) is the most common bacteria associated with infection after shoulder arthroplasty. These bacteria can be grown on culture of skin after standard preoperative skin preparation and antibiotics. The purpose of this study was to determine whether adding preoperative intravenous doxycycline reduces the prevalence of positive P. acnes cultures of skin and deep tissues at the time of prosthetic joint implantation during shoulder arthroplasty. METHODS: This was a randomized controlled trial...
June 6, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29863558/post-neurosurgical-temporal-deformities-various-techniques-for-correction-and-associated-complications
#10
Gabriel F Santiago, Jordan Terner, Amir Wolff, Jeffrey Teixeira, Henry Brem, Judy Huang, Chad R Gordon
INTRODUCTION: An irregular craniofacial contour along the temporal fossa, known commonly as 'temporal hollowing deformity,' (THD) can arise from multiple etiologies. In fact, up to half of all patients who undergo neurosurgical pterional dissections develop some form of temporal contour deformities. Unfortunately, temporal hollowing correction remains surgically challenging with many techniques resulting in high rates of failure and/or morbidity. METHODS: Herein, we describe anatomy contributing to postsurgical temporal deformity as well as time-tested prevention and surgical correction techniques...
May 31, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29863552/glabellar-rejuvenation-in-forehead-lift-reversed-periosteum-or-dermal-fat-graft-to-cover-pedicled-glabellar-flap
#11
Xiu-Qi Li, Jia-Qi Wang
Forehead aging is characterized by wrinkles, loss of skin elasticity, brow ptosis, and soft-tissue atrophy. For patients with prominent rhytids and marked brow ptosis, forehead lift is still the most effective treatment with a persisting result. In order to eliminate the glabellar wrinkles, forehead lift usually requires the removal of the corrugator supercilii muscle and procerus, which can lead to glabellar flattening or depression. Instead of muscle removal, the corrugator supercilii muscle, procerus, and the underlying galea were dissected as a pedicled glabellar flap...
May 31, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29851721/impact-of-acellular-dermal-matrix-on-postsurgical-wound-fluid-biomarkers-in-prosthetic-breast-reconstruction
#12
Henry C Hsia, Michael R Weaver, Jean E Schwarzbauer
BACKGROUND: Despite the widespread practice of using biologic scaffolds for soft tissue reinforcement over prosthetic implants, the impact of acellular dermal matrix (ADM) on surgical wound fluid biomarkers over the initial postoperative period after prosthetic breast reconstruction remains poorly understood. METHODS: Patients undergoing prosthetic breast reconstruction surgery where ADM was likely to be used were consented to have fluid samples collected from surgical drains after surgery...
May 30, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29806795/long-term-outcomes-of-bilateral-direct-to-implant-breast-reconstruction-in-women-at-high-breast-cancer-risk
#13
Victorien M T van Verschuer, Marc A M Mureau, Bernadette A M Heemskerk-Gerritsen, Pravesh S Gadjradj, Cleo Rogier, Cornelis Verhoef, Jessica P Gopie, Caroline Seynaeve, Linetta B Koppert
INTRODUCTION: Challenges of direct-to-implant breast reconstruction (BR) are to achieve sufficient implant coverage and lower pole projection. We assessed reoperation rates, long-term patient satisfaction and aesthetic outcome after direct-to-implant BR without acellular dermal matrix (ADM) in women with high breast cancer risk. METHODS: Women who underwent bilateral skin or nipple-sparing mastectomy and immediate direct-to-implant BR between 1994 and 2006 completed a survey on reoperations and the Breast-Q Reconstruction questionnaire...
May 28, 2018: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/29800083/outcomes-of-acellular-dermal-matrix-for-immediate-tissue-expander-reconstruction-with-radiotherapy-a-retrospective-cohort-study
#14
Elizabeth S Craig, Mark W Clemens, John C Koshy, James Wren, Zhang Hong, Charles Butler, Patrick Garvey, Jesse Selber, Steven Kronowitz
Background: Despite increasing literature support for the use of acellular dermal matrix (ADM) in expander-based breast reconstruction, the effect of ADM on clinical outcomes in the presence of post-mastectomy radiation therapy (PMRT) has not been well described. Objectives: To analyze the impact ADM plays on clinical outcomes on immediate tissue expander (ITE) reconstruction undergoing PMRT. Methods: We retrospectively reviewed patients who underwent ITE breast reconstruction from 2004 to 2014 at MD Anderson Cancer Center...
May 24, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29794505/use-of-a-vertical-muscle-sparing-latissimus-dorsi-flap-in-implant-based-breast-reconstruction-without-position-change-a-preliminary-report
#15
Hyung Chul Lee, Hyun Ho Han, Eun Key Kim
BACKGROUND: The use of various latissimus dorsi (LD) flap types in combination with implants is a safe and reliable 1-stage breast reconstruction method. However, 1 or more positional changes are generally required during the procedure. We designed a vertical skin paddle that was centered along the midaxillary line and harvested the required LD muscle amount based on the thoracodorsal artery descending branch, thereby completing flap elevation, inset, and donor-site closure in the supine position following skin-sparing mastectomy...
May 23, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29782983/an-in-vivo-biocompatibility-study-of-surgical-meshes-made-from-bacterial-cellulose-modified-with-chitosan
#16
Joanna Piasecka-Zelga, Piotr Zelga, Joanna Szulc, Justyna Wietecha, Danuta Ciechańska
Bacterial cellulose modified with chitosan (MBC) is an innovative biomaterial used in regenerative medicine which may potentially improve treatment outcomes mesh for hernia repair surgery by facilitating better absorption in native tissue with less risk of mesh-related infections. The aim of the present study was to evaluate the biocompatibility of mesh based on MBC, and determine whether immunological reactions occur due to hypersensitivity to the implants. Forty five Imp:WIST rats were randomly assigned to be implanted with one of three mesh types: simple polypropylene mesh (n = 15), mesh modified by bacterial cellulose only (n = 15) and MBC mesh (n = 15) and evaluated after one and three months following intramuscular implantation...
May 18, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29781849/breast-reconstruction-among-commercially-insured-women-with-breast-cancer-in-the-united-states
#17
Andrea Barnow, Todd Canfield, Ray Liao, Sashi Yadalam, Iftekhar Kalsekar, Rahul Khanna
INTRODUCTION: This study evaluated trends related to breast reconstruction and the factors associated with reconstruction. METHODS: Women with breast cancer aged 19 to 64 years who underwent a mastectomy procedure between July 1, 2011, and September 30, 2014, were identified from the MarketScan Commercial Claims and Encounters Database. The first date of surgical procedure during this period was defined as the index date. Continuous enrollment during the 12-month preindex and postindex period was required, and the patient sample was followed for 12 months postindex...
May 17, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29756539/skin-regeneration-with-a-scaffold-of-predefined-shape-and-bioactive-peptide-hydrogels
#18
Heejung Im, Su Hee Kim, Soo Hyun Kim, Youngmee Jung
We developed a highly elastic customized scaffold for soft-tissue regeneration and combined them with bioactive hydrogels with stem-cell-inducing ability. This was done to mimic mechanical properties of native soft tissues and improve the viability of transplanted cells as well as efficiency of tissue regeneration. The proposed study was aimed at evaluating various characteristics of scaffolds and investigating their tissue regenerating ability. Finger shaped porous scaffolds were successfully fabricated by an indirect 3D printing of poly (L-lactide-co-ε-caprolactone) (PLCL) which provides a high elasticity for soft tissue engineering...
May 14, 2018: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/29746276/deepithelialized-skin-reduction-preserves-skin-and-nipple-perfusion-in-immediate-reconstruction-of-large-and-ptotic-breasts
#19
Danielle H Rochlin, Dung H Nguyen
BACKGROUND: Women with large and/or ptotic breasts are often not considered candidates for nipple-sparing mastectomy (NSM) and/or immediate breast reconstruction given difficulties avoiding ischemic complications and achieving a favorable aesthetic result. We report a novel technique involving deepithelialized skin reduction to simultaneously reduce the skin envelope and preserve perfusion to the skin and nipple in immediate breast reconstruction for women that fit this high-risk anatomic profile...
April 30, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29718653/silk-sponges-ornamented-with-placenta-derived-extracellular-matrix-augments-full-thickness-cutaneous-wound-healing-by-stimulating-neovascularization-and-cellular-migration
#20
Arun Prabhu Rameshbabu, Kamakshi Bankoti, Sayanti Datta, Elavarasan Subramani, Anupam Apoorva, Paulomi Ghosh, Priti Prasanna Maity, Padmavati Manchikanti, Koel Chaudhury, Santanu Dhara
Regeneration of full-thickness wound without scar formation is a multifaceted process which depends on in situ dynamic interactions between the tissue-engineered skin substitutes and newly formed reparative tissue. However, the majority of the tissue-engineered skin substitutes used so far in full-thickness wound healing cannot mimic the natural extracellular matrix (ECM) complexity and thus are incapable of providing a suitable niche for endogenous tissue repair. Herein, we demonstrated a simple approach to fabricate porous Hybrid Extracellular Matrix Sponges (HEMS) using Placental Extracellular Matrix (pECM) and Silk Fibroin (SF) for full-thickness wound healing...
May 2, 2018: ACS Applied Materials & Interfaces
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