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https://www.readbyqxmd.com/read/28743177/traditional-suburethral-sling-operations-for-urinary-incontinence-in-women
#1
REVIEW
Haroon Rehman, Carlos A Bezerra, Homero Bruschini, June D Cody, Patricia Aluko
BACKGROUND: Stress urinary incontinence constitutes a significant health and economic burden to society. Traditional suburethral slings are one of the surgical operations used to treat women with symptoms of stress urinary incontinence. OBJECTIVES: To determine the effects of traditional suburethral slings on stress or mixed incontinence in comparison with other management options. SEARCH METHODS: We searched the Cochrane Incontinence Group Specialised Register (searched 3 June 2010) and the reference lists of relevant articles...
July 26, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28742771/perioperative-amino-acid-infusion-for-preventing-hypothermia-and-improving-clinical-outcomes-during-surgery-under-general-anesthesia-a-systematic-review-and-meta-analysis
#2
Yoshitaka Aoki, Yukie Aoshima, Kazuyuki Atsumi, Ryo Kaminaka, Rintaro Nakau, Kyoko Yanagita, Makiko Kora, Shunsuke Fujii, Junichiro Yokoyama
Amino acid (AA) infusion is sometimes selected to avoid hypothermia during general anesthesia. However, the widespread clinical use of AA infusion therapy has not been established. This study aimed to clarify the evidence that AA infusion can increase patient body temperature and improve clinical outcomes using the Grading of Recommendations Assessment, Development, and Evaluation system. We searched MEDLINE (PubMed), Cochrane Central Register of Controlled Trials, and Igaku Chuo Zasshi (Japana Centra Revuo Medicina) in November 2015...
July 24, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28741392/recent-advances-in-the-development-and-use-of-molecular-tests-to-predict-antimicrobial-resistance-in-neisseria-gonorrhoeae
#3
Valentina Donà, Nicola Low, Daniel Golparian, Magnus Unemo
The number of genetic tests, mostly real-time PCRs, to detect antimicrobial resistance (AMR) determinants and predict AMR in Neisseria gonorrhoeae is increasing. Several of these assays are promising, but there are important shortcomings and few assays have been adequately validated and quality assured. Areas covered: Recent advances, focusing on publications since 2012, in the development and use of molecular tests to predict gonococcal AMR for surveillance and for clinical use, advantages and disadvantages of these tests and of molecular AMR prediction compared with phenotypic AMR testing, and future perspectives for effective use of molecular AMR tests for different purposes...
July 25, 2017: Expert Review of Molecular Diagnostics
https://www.readbyqxmd.com/read/28741212/influence-of-orientation-glazing-proportion-and-zone-aspect-ratio-on-the-thermal-performance-of-buildings-during-the-winter-period
#4
Dimitrios G Zenginis, Karolos J Kontoleon
The objective of this study is to assess the effect of orientation, glazing proportion and aspect ratio of building zones on heat fluxes through their surfaces, under specific environmental conditions. The investigation is carried out for thermally-insulated building zones with a varying facade orientation corresponding to each cardinal point, during the winter period in the northern Greek region. For this purpose, three glazing-to-facade ratios (GR) are taken into account; along with the glazing ratio the influence of the glazing U value is also considered...
July 25, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28741005/the-pan-asian-resuscitation-outcomes-study-paros-clinical-research-network-what-where-why-and-how
#5
Nausheen Edwin Doctor, Nur Shahidah Binte Ahmad, Pin Pin Pek, Susan Yap, Marcus Eng Hock Ong
Out-of-hospital cardiac arrest (OHCA) is a global health concern with an incidence rate of 50-60 per 100,000 person-years. To improve OHCA survival rates, several cardiac arrest registries have been set up in North America and Europe, such as the Resuscitation Outcomes Consortium, Cardiac Arrest Registry to Enhance Survival, Ontario Prehospital Advanced Life Support and European Registry of Cardiac Arrest. In Asia, however, there was previously no concerted effort in prehospital emergency care research owing to differences in prehospital emergency medical services systems, data collection methods and outcome reporting between countries...
July 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28740943/potential-effects-of-whole-body-vibration-exercises-on-blood-flow-kinetics-of-different-populations-a-systematic-review-with-a-suitable-approach
#6
Danúbia Sá-Caputo, Laisa Paineiras-Domingos, Rafaelle Carvalho-Lima, Glenda Dias-Costa, Patrícia de Castro de Paiva, Claudia Figueiredo de Azeredo, Roberto Carlos Resende Carmo, Carla F Dionello, Eloá Moreira-Marconi, Éric Heleno F F Frederico, Cintia Renata Sousa-Gonçalves, Danielle S Morel, Dulciane N Paiva, Núbia C P Avelar, Ana C Lacerda, Carlos E V Magalhães, Leonardo S Castro, Giuseppe A Presta, Severo de Paoli, Borja Sañudo, Mario Bernardo-Filho
BACKGROUND: The ability to control skin blood flow decreases with advancing age and some clinical disorders, as in diabetes and in rheumatologic diseases. Feasible clinical strategies such as whole-body vibration exercise (WBVE) are being used without a clear understanding of its effects. The aim of the present study is to review the effects of the WBVE on blood flow kinetics and its feasibility in different populations. MATERIAL AND METHODS: The level of evidence (LE) of selected papers in PubMed and/or PEDRo databases was determined...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28740745/investigating-the-running-abilities-of-tyrannosaurus-rex-using-stress-constrained-multibody-dynamic-analysis
#7
William I Sellers, Stuart B Pond, Charlotte A Brassey, Philip L Manning, Karl T Bates
The running ability of Tyrannosaurus rex has been intensively studied due to its relevance to interpretations of feeding behaviour and the biomechanics of scaling in giant predatory dinosaurs. Different studies using differing methodologies have produced a very wide range of top speed estimates and there is therefore a need to develop techniques that can improve these predictions. Here we present a new approach that combines two separate biomechanical techniques (multibody dynamic analysis and skeletal stress analysis) to demonstrate that true running gaits would probably lead to unacceptably high skeletal loads in T...
2017: PeerJ
https://www.readbyqxmd.com/read/28739478/an-overview-of-clinical-guidelines-for-the-management-of-vertebral-compression-fracture-a-systematic-review
#8
REVIEW
Patrícia Parreira, Chris G Maher, Rodrigo Z Megale, Lyn March, Manuela L Ferreira
BACKGROUND CONTEXT: Vertebral compression fractures are the most common type of osteoporotic fracture comprising approximately 1.4 million cases worldwide. Clinical practice guidelines can be powerful tools for promoting evidence-based practice, as they integrate research findings in order to support decision-making. However, currently available clinical guidelines and recommendations, established by different medical societies, are sometimes contradictory. PURPOSE: The aim of this study was to appraise the recommendations and methodological quality of international clinical guidelines for the management of VCFs...
July 21, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28739332/effects-of-voice-therapy-on-muscle-tension-dysphonia-a-systematic-literature-review
#9
REVIEW
Gabriela da Cunha Pereira, Isadora de Oliveira Lemos, Camila Dalbosco Gadenz, Mauriceia Cassol
The present study aimed to carry out a systematic review of the effects of voice therapy on individuals diagnosed with muscle tension dysphonia (MTD) or hyperfunctional dysphonia. This is a systematic literature review on the databases Medline (via PubMed), Cochrane Library, Scopus, and Lilacs using a search strategy related to the theme of the study. The selection included clinical trials that assessed the effects of speech therapy intervention on patients diagnosed with MTD or hyperfunctional dysphonia published over the last 10 years in Portuguese, English, or Spanish...
July 21, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28739221/structure-and-computation-in-immunoreagent-design-from-diagnostics-to-vaccines
#10
REVIEW
Louise Gourlay, Claudio Peri, Martino Bolognesi, Giorgio Colombo
Novel immunological tools for efficient diagnosis and treatment of emerging infections are urgently required. Advances in the diagnostic and vaccine development fields are continuously progressing, with reverse vaccinology and structural vaccinology (SV) methods for antigen identification and structure-based antigen (re)design playing increasingly relevant roles. SV, in particular, is predicted to be the front-runner in the future development of diagnostics and vaccines targeting challenging diseases such as AIDS and cancer...
July 21, 2017: Trends in Biotechnology
https://www.readbyqxmd.com/read/28739060/organizational-support-workload-and-intent-to-stay-work-environment-perceptions-in-perianesthesia-nursing-units
#11
Jacqueline Ross
PURPOSE: The purpose of this ASPAN study was to understand perianesthesia nurses' perception of their work environments in regards to organizational support, workload, intent to stay, and overall nurse satisfaction. DESIGN: A descriptive design was used with survey methodology. METHOD: An online survey was sent to American Society of PeriAnesthesia Nurses members. The Individual Workload Perception Scale-Revised was used. A total of 2,121 American Society of PeriAnesthesia Nurses members participated (21% response rate)...
August 2017: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/28739043/pocket-detection-and-interaction-weighted-ligand-similarity-search-yields-novel-high-affinity-binders-for-myocilin-olf-a-protein-implicated-in-glaucoma
#12
Bharath Srinivasan, Sam Tonddast-Navaei, Jeffrey Skolnick
Traditional structure and ligand based virtual screening approaches rely on the availability of structural and ligand binding information. To overcome this limitation, hybrid approaches were developed that relied on extraction of ligand binding information from proteins sharing similar folds and hence, evolutionarily relationship. However, they cannot target a chosen pocket in a protein. To address this, a pocket centric virtual ligand screening approach is required. Here, we employ a new, iterative implementation of a pocket and ligand-similarity based approach to virtual ligand screening to predict small molecule binders for the olfactomedin domain of human myocilin implicated in glaucoma...
July 12, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28738857/investigating-interventions-to-increase-uptake-of-hiv-testing-and-linkage-into-care-or-prevention-for-male-partners-of-pregnant-women-in-antenatal-clinics-in-blantyre-malawi-study-protocol-for-a-cluster-randomised-trial
#13
Augustine T Choko, Katherine Fielding, Nigel Stallard, Hendramoorthy Maheswaran, Aurelia Lepine, Nicola Desmond, Moses K Kumwenda, Elizabeth L Corbett
BACKGROUND: Despite large-scale efforts to diagnose people living with HIV, 54% remain undiagnosed in sub-Saharan Africa. The gap in knowledge of HIV status and uptake of follow-on services remains wide with much lower rates of HIV testing among men compared to women. Here, we design a study to investigate the effect on uptake of HIV testing and linkage into care or prevention of partner-delivered HIV self-testing alone or with an additional intervention among male partners of pregnant women...
July 24, 2017: Trials
https://www.readbyqxmd.com/read/28738681/optimizing-high-resolution-mass-spectrometry-for-the-identification-of-low-abundance-post-translational-modifications-of-intact-proteins
#14
Lisa E Kilpatrick, Eric L Kilpatrick
Intact protein analysis by liquid chromatography-mass spectrometry (LC-MS) is now possible due to the improved capabilities of mass spectrometers yielding greater resolution, mass accuracy, and extended mass ranges. Concurrent measurement of post-translational modifications (PTMs) during LC-MS of intact proteins is advantageous while monitoring critical proteoform status, such as for clinical samples or during production of reference materials. However, difficulties exist for PTM identification when the protein is large or contains multiple modification sites...
July 25, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28738652/volatile-composition-of-merlot-red-wine-and-its-contribution-to-the-aroma-optimization-and-validation-of-analytical-method
#15
Stefany Grützmann Arcari, Vinicius Caliari, Marla Sganzerla, Helena Teixeira Godoy
A methodology for the determination of volatile compounds in red wine using headspace solid phase microextraction (HS-SPME) combined with gas chromatography-ion trap/ mass spectrometry (GC-IT/MS) and flame ionization detector (GC -FID) was developed, validated and applied to a sample of Brazilian red wine. The optimization strategy was conducted using the Plackett-Burman design for variable selection and central composite rotational design (CCRD). The response surface methodology showed that the performance of the extraction of the volatile compounds using divinylbenzene/carboxen/polydimethylsiloxane (DVB/CAR/PDMS) fiber is improved with no sample dilution, the addition of 30% NaCl, applying an extraction temperature of 56°C and extraction time of 55min...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28738575/analytical-methodology-for-the-electro-catalytic-determination-of-estradiol-and-progesterone-based-on-graphene-quantum-dots-and-poly-sulfosalicylic-acid-co-modified-electrode
#16
Majid Arvand, Shiva Hemmati
The goal of this study was to develop an electroanalytical method for the simultaneous determination of steroid hormones for the first time. The key factor in the electrochemical methods is the choice of suitable electrode materials. For this purpose, graphene quantum dots (GQDs) doped poly(sulfosalicylic acid) (PSSA) was immobilized on a glassy carbon electrode (GCE). Apart from exhibition strong and stable electrocatalytic response towards estradiol (E2) and progesterone (P4), the proposed sensor was able to distinguish two hormone's oxidation peaks clearly...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28738443/urethral-injection-therapy-for-urinary-incontinence-in-women
#17
REVIEW
Vivienne Kirchin, Tobias Page, Phil E Keegan, Kofi Om Atiemo, June D Cody, Samuel McClinton, Patricia Aluko
BACKGROUND: Urinary incontinence imposes a significant health and economic burden to society. Periurethral or transurethral injection of bulking agents is a minimally invasive surgical procedure used as one the surgical treatments of stress urinary incontinence (SUI) in adult women. OBJECTIVES: To assess the effects of periurethral or transurethral injection therapy on the cure or improvement of urinary incontinence in women. SEARCH METHODS: We searched the Cochrane Incontinence Group Specialised Trials Register (searched 8 November 2010) and the reference lists of relevant articles...
July 25, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28738257/a-systematic-review-of-the-quality-of-statistical-methods-employed-for-analysing-quality-of-life-data-in-cancer-randomised-controlled-trials
#18
REVIEW
Jean-Francois Hamel, Patrick Saulnier, Madeline Pe, Efstathios Zikos, Jammbe Musoro, Corneel Coens, Andrew Bottomley
AIMS: Over the last decades, Health-related Quality of Life (HRQoL) end-points have become an important outcome of the randomised controlled trials (RCTs). HRQoL methodology in RCTs has improved following international consensus recommendations. However, no international recommendations exist concerning the statistical analysis of such data. The aim of our study was to identify and characterise the quality of the statistical methods commonly used for analysing HRQoL data in cancer RCTs...
July 21, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28738092/the-efficacy-of-jianpi-yiqi-therapy-for-chronic-atrophic-gastritis-a-systematic-review-and-meta-analysis
#19
Yun-Kai Dai, Yun-Zhan Zhang, Dan-Yan Li, Jin-Tong Ye, Ling-Feng Zeng, Qi Wang, Ling Hu
Jianpi Yiqi therapy (JYT) is a classical therapy in treating chronic atrophic gastritis (CAG), but the clinical effects of it are still contentious. The purpose of this article is to evaluate the efficacy and safety of JYT for CAG. Seven electronic databases including PubMed, Embase, Springer Link, CNKI (China National Knowledge Infrastructure), VIP (Chinese Scientific Journals Database), Wan-fang database, and CBM (Chinese Biomedicine Database) were searched from their inception to November 1, 2016. 13 randomized controlled trials (RCTs) with a total of 1119 participants were identified for analysis...
2017: PloS One
https://www.readbyqxmd.com/read/28737439/systematic-review-and-meta-analysis-is-bowel-preparation-still-necessary-in-small-bowel-capsule-endoscopy
#20
Diana E Yung, Emanuele Rondonotti, Catherine Sykes, Marco Pennazio, John N Plevris, Anastastios Koulaouzidis
INTRODUCTION: Optimal bowel preparation for small bowel capsule endoscopy(SBCE) is controversial. This meta-analysis aimed to investigate the effects of laxatives in SBCE. METHODS: A comprehensive literature search was conducted for studies investigating the use of laxatives in SBCE. The primary outcome was diagnostic yield(DY) for SB findings; secondary outcomes SB visualization quality(SBVQ) and completion rate(CR). Pooled odds ratios(ORs) with 95% confidence intervals(CIs) and number needed to treat(NNT) were calculated...
July 24, 2017: Expert Review of Gastroenterology & Hepatology
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