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https://www.readbyqxmd.com/read/28222551/the-top-100-cited-neurorehabilitation-papers
#1
Jeffrey S Kreutzer, Amma A Agyemang, David Weedon, Nathan Zasler, Melissa Oliver, Aaron A Sorensen, Saskia van Wijngaarden, Eileen Leahy
BACKGROUND: Neurorehabilitation covers a large range of disorders, treatment approaches and methods. There have been previous citation analyses of rehabilitation and of its subfields. However, there has never been a comprehensive citation analysis in neurorehabilitation. OBJECTIVE: The present study reports findings from a citation analysis of the top 100 most cited neurorehabilitation papers to describe the research trends in the field. METHODS: A de-novo keyword search of papers indexed in the Web of Science Core Collection database yielded 52,581 papers...
January 7, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28222539/technologies-assessing-limb-bradykinesia-in-parkinson-s-disease
#2
Hasan Hasan, Dilan S Athauda, Thomas Foltynie, Alastair J Noyce
BACKGROUND: The MDS-UPDRS (Movement Disorders Society - Unified Parkinson's Disease Rating Scale) is the most widely used scale for rating impairment in PD. Subscores measuring bradykinesia have low reliability that can be subject to rater variability. Novel technological tools can be used to overcome such issues. OBJECTIVE: To systematically explore and describe the available technologies for measuring limb bradykinesia in PD that were published between 2006 and 2016...
2017: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/28222506/synaptic-compensation-as-a-probable-cause-of-prolonged-mild-cognitive-impairment-in-alzheimer-s-disease-implications-from-a-transgenic-mouse-model-of-the-disease
#3
Narjes Baazaoui, Michael Flory, Khalid Iqbal
Alzheimer's disease (AD) is a slow, progressive neurodegenerative disease in which cognitive decline takes place over a period of several years with a very variable period of mild cognitive impairment (MCI) and, in some cases, relatively long period before progression to dementia. The cognitive deficit during MCI is probably due to neuronal loss, an intermediate level of amyloid-β (Aβ) plaques and neurofibrillary tangles (NFT) and synaptosis, which is interrupted with a transient compensatory increase. We found impairment in reference memory accompanied by a decrease in the expression of synaptophysin, β-III tubulin, and MAP2 and a trend for GluR1, at 12 weeks of age in 3xTg-AD mice (hAPPSwe, P301L tau, PS1 [M146V] knock-in), a widely used transgenic model of AD...
February 7, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28222490/the-prevalence-of-convergence-insufficiency-in-iran-a-population-based-study
#4
Hassan Hashemi, Payam Nabovati, Mehdi Khabazkhoob, Hadi Ostadimoghaddam, Asgar Doostdar, Ehsan Shiralivand, Abbasali Yekta
PURPOSE: The aim was to determine the prevalence of convergence insufficiency and its relationship with age, gender and refractive error in a population-based study. METHODS: In this cross-sectional study, all residents over one year old in Mashhad city, in the north east of Iran, were sampled through random stratified cluster sampling. After selecting samples and their participation in the study, they all had eye examinations including the measurement of visual acuity, refraction, binocular vision assessment, including cover test, measurement of near point of convergence and fusional vergences and finally, slitlamp biomicroscopy...
February 21, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28222431/the-routine-use-of-intrapartum-ultrasound-in-clinical-decision-making-during-the-second-stage-of-labor-does-it-have-any-impact-on-delivery-outcomes
#5
Oren Barak, Roni Levy, Orna Flidel, Svetlana Zaks, Moshe Gillor, Zion Hagay, Edi Vaisbuch
BACKGROUND/AIMS: The study aimed to assess whether the use of intrapartum transperineal ultrasound (US) can reduce the rate of failed vacuum extraction (VE). METHODS: This is a retrospective cohort study including all women delivering at term with the diagnosis of protracted second stage of labor. The mode of delivery and rate of failed VE were compared between women who underwent a US examination prior to the decision on obstetrical interventions ("+US" group) and those in whom clinical decisions were based upon digital assessment only ("no-US" group)...
February 22, 2017: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/28222412/low-risk-papillary-thyroid-carcinoma-patients-who-underwent-near-total-thyroidectomy-without-prophylactic-central-compartment-lymph-node-dissection-and-were-ablated-with-low-dose-50mci-rai-had-excellent-10-year-prognosis
#6
Marina Michalaki, Panagiotis Bountouris, Nikolaos D Roupas, Anastasia Theodoropoulou, Niki Agalianou, Theodoros Alexandrides, Kostas Markou
BACKGROUND: The current trend in the management of low risk differentiated thyroid carcinoma is to follow less aggressive strategies. OBJECTIVE: To assess the long-term morbidity and mortality outcomes of low-risk papillary thyroid carcinoma (PTC) patients undergoing minimal intervention. DESIGN: We retrospectively analyzed 137 patients with low-risk PTC (stage I: n=77; stage II: n=60). Of these patients, 107 (Group 1) had macro-PTC and underwent near-total thyroidectomy and received postoperatively 50mCi RAI...
October 2016: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28222399/improved-yeast-delivery-of-fluconazole-with-a-nanostructured-lipid-carrier-system
#7
Hamid Reza Kelidari, Maryam Moazeni, Roghayeh Babaei, Majid Saeedi, Jafar Akbari, Parisa Islami Parkoohi, Mojtaba Nabili, Atefeh Abdollahi Gohar, Katayoun Morteza-Semnani, Ali Nokhodchi
Despite the growing trends in the number of patients at risk for invasive fungal infections, management with current antifungal agents results in complications due to changes in the epidemiology and drug susceptibility of invasive fungal infections. In the present research fluconazole-loaded nanostructured lipid carriers were prepared using probe ultrasonication techniques and investigated the efficacy of the optimal formulation on a large number of Candida species. The morphology of the obtained nanostructured lipid carriers was characterized by transmission-electron microscopy...
February 17, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28222340/a-comparative-retrospective-exploration-of-the-profiles-of-patients-in-south-africa-diagnosed-with-epileptic-and-psychogenic-non-epileptic-seizures
#8
David G Anderson, Maria Damianova, Skye Hanekom, Marilyn Lucas
Psychogenic non-epileptic seizures (PNES) have a high prevalence globally but the accurate diagnosis of this condition still remains a challenge. This is particularly the case in countries where there is scarce expertise and insufficient affordable medical facilities to which patients have access. The rate of PNES diagnosis in epilepsy units is typically within the range of 20 to 30%. In the context of developing countries, this rate tends to be higher and increases demand on the existing scarce health care capacities...
February 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28222232/dietary-total-antioxidant-capacity-in-early-school-age-and-subsequent-allergic-disease
#9
Anna Gref, Susanne Rautiainen, Olena Gruzieva, Niclas Håkansson, Inger Kull, Göran Pershagen, Magnus Wickman, Alicja Wolk, Erik Melén, Anna Bergström
BACKGROUND: Dietary antioxidant intake has been hypothesized to influence the development of allergic diseases, however, few prospective studies have investigated this association. OBJECTIVE: Our aim was to study the association between total antioxidant capacity (TAC) of the diet at age 8 years and the subsequent development of asthma, rhinitis and sensitization to inhalant allergens between 8 and 16 years, and to assess potential effect modification by known risk factors...
February 21, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28222194/forecasting-outpatient-visits-using-empirical-mode-decomposition-coupled-with-back-propagation-artificial-neural-networks-optimized-by-particle-swarm-optimization
#10
Daizheng Huang, Zhihui Wu
Accurately predicting the trend of outpatient visits by mathematical modeling can help policy makers manage hospitals effectively, reasonably organize schedules for human resources and finances, and appropriately distribute hospital material resources. In this study, a hybrid method based on empirical mode decomposition and back-propagation artificial neural networks optimized by particle swarm optimization is developed to forecast outpatient visits on the basis of monthly numbers. The data outpatient visits are retrieved from January 2005 to December 2013 and first obtained as the original time series...
2017: PloS One
https://www.readbyqxmd.com/read/28222015/plasma-levels-of-endothelin-1-and-renal-function-among-young-and-healthy-adults
#11
Andreas Fischer, Matthias Bossard, Stefanie Aeschbacher, Peter Egli, Carolin Cordewener, Joel Estis, John Todd, Martin Risch, Lorenz Risch, David Conen
BACKGROUND: Endothelin-1 (ET-1), a vasoconstrictive and pro-inflammatory peptide, is associated with several cardiovascular risk factors and outcomes. We aimed to investigate the association of plasma ET-1 levels and renal function among young and healthy adults. METHODS: Individuals aged 25-41 years were enrolled in a population-based cohort study. Main exclusion criteria were established kidney disease, cardiovascular diseases, diabetes mellitus and a body mass index>35 kg/m2...
February 21, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28221997/topkube-a-rank-aware-data-cube-for-real-time-exploration-of-spatiotemporal-data
#12
Fabio Miranda, Lauro Lins, James Klosowski, Claudio Silva
From economics to sports to entertainment and social media, ranking objects according to some notion of importance is a fundamental tool we humans use all the time to better understand our world. With the ever-increasing amount of user-generated content found online, "what's trending" is now a commonplace phrase that tries to capture the zeitgeist of the world by ranking the most popular microblogging hashtags in a given region and time. However, before we can understand what these rankings tell us about the world, we need to be able to more easily create and explore them, given the significant scale of today's data...
February 17, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28221934/effect-of-process-temperature-on-virus-inactivation-during-high-hydrostatic-pressure-processing-of-contaminated-fruit-puree-and-juice
#13
Hao Pan, Matthew Buenconsejo, Karl F Reineke, Y Carol Shieh
High pressure processing (HPP) can inactivate pathogens and retain fruit qualities. Elevated HPP pressure or time increases virus inactivation, but the effect of temperature is not consistently observed for norovirus and hepatitis A virus. In the present study, the effectiveness of HPP holding temperatures (<40°C) and pressures were evaluated for inactivating surrogates (murine norovirus [MNV] and MS2 coliphage) in pomegranate and strawberry juices and strawberry puree using a 24-liter HPP system. The holding temperature was established by setting the HPP initial temperature via pretrials...
September 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28221916/characterization-and-antimicrobial-resistance-of-salmonella-typhimurium-isolates-from-clinically-diseased-pigs-in-korea
#14
Sang-Ik Oh, Jong Wan Kim, Myeongju Chae, Ji-A Jung, Byungjae So, Bumseok Kim, Ha-Young Kim
This study investigated the prevalence of Salmonella enterica serovar and antimicrobial resistance in Salmonella Typhimurium isolates from clinically diseased pigs collected from 2008 to 2014 in Korea. Isolates were also characterized according to the presence of antimicrobial resistance genes and pulsed-field gel electrophoresis patterns. Among 94 Salmonella isolates, 81 (86.2%) were identified as being of the Salmonella Typhimurium serotype, followed by Salmonella Derby (6 of 94, 6.4%), Salmonella 4,[5],12:i:- (4 of 94, 4...
November 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28221855/survival-kinetics-of-salmonella-enterica-and-enterohemorrhagic-escherichia-coli-on-a-plastic-surface-at-low-relative-humidity-and-on-low-water-activity-foods
#15
Hidekazu Hokunan, Kento Koyama, Mayumi Hasegawa, Shuso Kawamura, Shigenobu Koseki
We investigated the survival kinetics of Salmonella enterica and enterohemorrhagic Escherichia coli under various water activity (aw) conditions to elucidate the net effect of aw on pathogen survival kinetics and to pursue the development of a predictive model of pathogen survival as a function of aw. Four serotypes of S. enterica (Stanley, Typhimurium, Chester, and Oranienburg) and three serotypes of enterohemorrhagic E. coli ( E. coli O26, E. coli O111, and E. coli O157:H7) were examined. These bacterial strains were inoculated on a plastic plate surface at a constant relative humidity (RH) (22, 43, 58, 68, or 93% RH, corresponding to the aw) or on a surface of almond kernels (aw 0...
October 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28221786/chemical-trends-in-solid-alkali-pertechnetates
#16
Jamie Weaver, Chuck Z Soderquist, Nancy M Washton, Andrew S Lipton, Paul L Gassman, Wayne W Lukens, Albert A Kruger, Nathalie A Wall, John S McCloy
Insight into the solid-state chemistry of pure technetium-99 ((99)Tc) oxides is required in the development of a robust immobilization and disposal system for nuclear waste stemming from the radiopharmaceutical industry, from the production of nuclear weapons, and from spent nuclear fuel. However, because of its radiotoxicity and the subsequent requirement of special facilities and handling procedures for research, only a few studies have been completed, many of which are over 20 years old. In this study, we report the synthesis of pure alkali pertechnetates (sodium, potassium, rubidium, and cesium) and analysis of these compounds by Raman spectroscopy, X-ray absorption spectroscopy (XANES and EXAFS), solid-state nuclear magnetic resonance (static and magic angle spinning), and neutron diffraction...
February 21, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28221389/optical-electrical-and-magnetic-properties-of-lanthanum-strontium-manganite-la1-xsrxmno3-synthesized-through-the-citrate-combustion-method
#17
Ali Omar Turky, Mohamed Mohamed Rashad, Ali Mostafa Hassan, Elsayed M Elnaggar, Mikhael Bechelany
Generally, strontium-doped lanthanum manganites (LSM) are materials connected ordinarily as cathodes in the solid oxide fuel cell (SOFC). In this study, the structural, optical, electrical and magnetic properties of La1-xSrxMnO3 (x = 0.2, 0.5, 0.8) synthesized using an organic acid precursor strategy were investigated, based on using citric acid as a fuel. Evidently, the results disclosed that a pure single monoclinic LSM phase was obtained from the thermally treated precursors annealed at 1000 °C with an annealing time of 2 h...
February 21, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28221363/premature-primary-tooth-eruption-in-cognitive-motor-delayed-adnp-mutated-children
#18
I Gozes, A Van Dijck, G Hacohen-Kleiman, I Grigg, G Karmon, E Giladi, M Eger, Y Gabet, M Pasmanik-Chor, E Cappuyns, O Elpeleg, R F Kooy, S Bedrosian-Sermone
A major flaw in autism spectrum disorder (ASD) management is late diagnosis. Activity-dependent neuroprotective protein (ADNP) is a most frequent de novo mutated ASD-related gene. Functionally, ADNP protects nerve cells against electrical blockade. In mice, complete Adnp deficiency results in dysregulation of over 400 genes and failure to form a brain. Adnp haploinsufficiency results in cognitive and social deficiencies coupled to sex- and age-dependent deficits in the key microtubule and ion channel pathways...
February 21, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28221266/body-mass-index-and-the-association-with-vaso-occlusive-crises-in-pediatric-sickle-cell-disease
#19
Andrea Zivot, Nataly Apollonsky, Edward Gracely, Deepti Raybagkar
BACKGROUND: Children with sickle cell disease (SCD) historically have been underweight and have poor overall growth. Recent studies have demonstrated a trend toward obesity in pediatric SCD populations. MATERIALS AND METHODS: Through retrospective chart review of patients with SCD followed at our center, we collected patient's data, including body mass index (BMI), weight percentiles, sickle cell genotype, baseline hemoglobin, medical and psychiatric comorbidities, 25-hydroxy vitamin D level, treatment with hydroxyurea, and chronic transfusions...
February 17, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28221220/impact-of-the-united-states-preventive-services-task-force-d-recommendation-on-prostate-cancer-screening-and-staging
#20
Renu S Eapen, Annika Herlemann, Samuel L Washington, Matthew R Cooperberg
PURPOSE OF REVIEW: In 2012, the United States Preventive Services Task Force (USPSTF) issued a grade 'D' recommendation against the use of routine prostate-specific antigen (PSA)-based screening for any men. This recommendation reflects critical misinterpretations of the available evidence base regarding benefits and harms of PSA screening and has influenced the nationwide landscape of prostate cancer screening, diagnosis, and treatment. RECENT FINDINGS: Following the USPSTF recommendation, a substantial decline in PSA screening was noted for all age groups...
February 17, 2017: Current Opinion in Urology
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