keyword
MENU ▼
Read by QxMD icon Read
search

randomized placebo controlled study to treat post operative pain

keyword
https://www.readbyqxmd.com/read/27765686/ef%C3%AF-cacy-of-10-sucralfate-ointment-after-anal-fistulotomy-a-prospective-double-blind-randomized-placebo-controlled-trial
#1
Mina Alvandipour, Shahram Ala, Hasan Tavakoli, Jamshid Yazdani Charati, Afshin Shiva
INTRODUCTION: The most frequent problems after anal fistulotomy are pain, bleeding, and delayed or impaired wound healing. Topical Sucralfate preparation has been used to treat a wide variety of wounds. In this study, we investigate effects of 10% sucralfate ointment on wound healing and postoperative pain after fistulotomy. METHODS AND MATERIALS: A total of 41 patients undergoing anorectal fistulotomy were included in this randomized, blinded, controlled trial and were randomly allocated to either sucralfate ointment (every 12 h) or placebo...
October 17, 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/27676661/comparative-effectiveness-of-suprascapular-nerve-block-in-the-relief-of-acute-post-operative-shoulder-pain-a-systematic-review-and-meta-analysis
#2
Ke-Vin Chang, Wei-Ting Wu, Chen-Yu Hung, Der-Sheng Han, Rong-Sen Yang, Chung-Hsun Chang, Chih-Peng Lin
BACKGROUND: The suprascapular nerve accounts for 70% of shoulder sensory innervations, and suprascapular nerve block (SSNB) has been shown to be effective in the relief of chronic shoulder pain including rotator cuff tendinitis, subdeltoid impingement syndrome, and adhesive capsulitis. However, this remains inconclusive for patients undergoing surgery. The present meta-analysis aimed to explore the effectiveness of SSNB for relieving acute post-operative shoulder pain. OBJECTIVE: To explore the effectiveness of SSNB for relieving acute post-operative shoulder pain...
September 2016: Pain Physician
https://www.readbyqxmd.com/read/26777769/effects-of-ozone-therapy-on-the-early-healing-period-of-deepithelialized-gingival-grafts-a-randomized-placebo-controlled-clinical-trial
#3
Zekeriya Taşdemir, Banu Arzu Alkan, Haydar Albayrak
BACKGROUND: This study evaluates the effects of ozone therapy (OT) on the early healing period of deepithelialized gingival grafts (DGG) placed for non-root coverage gingival augmentation by laser Doppler flowmetry (LDF). METHODS: Thirty-three patients were assigned to study groups: 1) test: DGG + OT; or 2) control group: DGG alone. Thirty patients completed the study. Ozone was applied on DGGs placed in the recipient bed and donor site immediately after surgery and at days 1 and 3 post-surgery...
June 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/26622385/efficacy-of-celecoxib-for-acute-pain-management-following-total-hip-arthroplasty-in-elderly-patients-a-prospective-randomized-placebo-control-trial
#4
Jia Chen, Wei Zhu, Zhenxiang Zhang, Lixian Zhu, Wenjie Zhang, Yaqing DU
The aim of the present study was to determine whether celecoxib is able to ameliorate pain intensity, provide a narcotic-sparing effect, achieve early ambulation and improve rehabilitation following total hip arthroplasty (THA) in elderly patients. Peri- and post-operative oral celecoxib was administered to verify the efficacy of celecoxib for acute pain management in a multimodal analgesic strategy. All 64 eligible patients were randomly allocated to either the celecoxib group, who took an oral 400 mg capsule of celecoxib peri-operatively and 200 mg per 12 h post-operatively for the first 5 days, or the control group, who were orally treated with a placebo capsule having the same appearance...
August 2015: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/26596627/tumor-necrosis-factor-%C3%AE-blockade-in-recurrent-and-disabling-chronic-sciatica-associated-with-post-operative-peridural-lumbar-fibrosis-results-of-a-double-blind-placebo-randomized-controlled-study
#5
RANDOMIZED CONTROLLED TRIAL
Christelle Nguyen, Clémence Palazzo, Sophie Grabar, Antoine Feydy, Katherine Sanchez, Nathalie Zee, Laurent Quinquis, Myriam Ben Boutieb, Michel Revel, Marie-Martine Lefèvre-Colau, Serge Poiraudeau, François Rannou
INTRODUCTION: The aim of this study was to assess the efficacy and safety of tumor necrosis factor (TNF)-α inhibition with infliximab (IFX) in treating recurrent and disabling chronic sciatica pain associated with post-operative peridural lumbar fibrosis. METHOD: A double-blind, placebo-controlled study randomized 35 patients presenting with sciatica pain associated with post-operative peridural lumbar fibrosis to two groups: IFX (n = 18), a single intravenous injection of 3 mg/kg IFX; and placebo (n = 17), a single saline serum injection...
November 19, 2015: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/26361810/randomized-placebo-controlled-study-of-the-efficacy-of-a-calcium-phosphate-containing-paste-on-dentin-hypersensitivity
#6
Deepak Mehta, Vishwas Gowda, Werner J Finger, Keiichi Sasaki
OBJECTIVE: Hypersensitivity of non-carious cervical lesions (DH) is a frequently encountered disease. This randomized, controlled, single-blind crossover study evaluated the effectiveness of a calcium phosphate containing desensitizer paste (TAP) on DH in comparison to water as placebo (PLA). METHODS: In this clinical trial 35 patients were randomly assigned to the test and the negative control group. Using a 10cm long VAS (visual analog scale) patients should respond with DH score >6 on one tooth in each of two quadrants for allocation...
November 2015: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/25828692/no-effect-of-the-cyclooxygenase-2-inhibitor-etoricoxib-on-pre-emptive-and-post-operative-analgesia-in-visceral-surgery-results-of-a-randomized-controlled-trial
#7
RANDOMIZED CONTROLLED TRIAL
J Fleckenstein, N Kohls, E Evtouchenko, L Lehmeyer, S Kramer, P M Lang, M Siebeck, T Mussack, R Hatz, B Heindl, P Conzen, M Rehm, S Czerner, B Zwißler, D Irnich
BACKGROUND: Pre-emptive analgesia in perioperative care has potential benefits for patients. The pre-emptive and postoperative analgesic effects of the cyclooxygenase-2 inhibitor etoricoxib have been investigated using a 2 × 2 factorial trial design. METHODS: According to the 2 × 2 factorial study design, 103 patients scheduled for visceral surgery, were randomly allocated to two groups prior to surgery. Patients could receive either etoricoxib or placebo (to investigate pre-emptive analgesia)...
February 2016: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/25041495/continuous-wound-infiltration-with-ropivacaine-for-analgesia-after-caesarean-section-a-randomised-placebo-controlled-trial
#8
RANDOMIZED CONTROLLED TRIAL
M Reinikainen, S Syväoja, K Hara
BACKGROUND: We evaluated the analgesic effect of ropivacaine infiltration into the surgical wound after caesarean section. METHODS: In a double-blind trial, 67 patients who were scheduled for caesarean section under spinal anaesthesia were randomly assigned to receive either 0.75% ropivacaine or placebo (NaCl 0.9%) through a multi-orifice catheter that was placed into the surgical wound, between the muscle fascia and the subcutaneous tissue. The study drug was administered as a bolus of 10 ml at the end of the operation, followed by an infusion at 2 ml/h for 48 h...
September 2014: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/24511715/misoprostol-for-cervical-ripening-prior-to-manual-vacuum-aspiration-mva-in-abnormal-uterine-bleeding-double-blinded-randomized-controlled-trialt
#9
RANDOMIZED CONTROLLED TRIAL
Wongsa Maneesorn, Athita Chanthasenanont, Kornkarn Bhamarapravatana, Komsun Suwannarurk
OBJECTIVE: To study the effectiveness of sublingual misoprostol for cervical ripening before MVA in women aged between 35 and 55 years old. MATERIAL AND METHOD: Women aged between 35 and 55 years old who had indications for endometrial sampling were recruited. Exclusion criteria were gross pathology of cervix, pregnancy, allergy to misoprostol, and abnormal coagulopathy. Eighty women who had indication for MVA were then assigned by randomization (block of four)...
December 2013: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
https://www.readbyqxmd.com/read/24427649/use-of-intravenous-steroids-at-induction-of-anesthesia-for-septoplasty-to-reduce-post-operative-nausea-and-vomiting-and-pain-a-double-blind-randomized-controlled-trial
#10
Ali Eftekharian, Navid Ahmady Roozbahany
To determine the effectiveness of dexamethasone to reduce pain, nausea and vomiting after septoplasty. Study is a prospective double-blind randomized controlled trial. A total of 90 patients were enrolled and received an either of dexamethasone or placebo in the induction of anesthesia. The patients were asked to note the level of pain on the visual analogue scale in the first 24 h after surgery. They also had to record their severity of nausea and number of vomiting attacks. There were statistically significant differences between the two groups for the level of pain noted on the visual analogue scale...
August 2013: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/24250987/multimodal-preincisional-premedication-to-prevent-acute-pain-after-cholecystectomy
#11
Dawood Aghamohammadi, Hamzeh Hosseinzadeh, Mahmood Eidy, Zahra Mohammadzadeh Vizhe, Mohammad Bassir Abolghasemi Fakhri, Reza Movassaghi, Kamyar Ghabili, Samad Ej Golzari
INTRODUCTION: Postoperative pain as an important medical concern is usually treated by opioids which also are of various inevitable side effects. The aim of this study was to assess the efficacy of multimodal preincisional premedication on preventing post-cholecystectomy acute pain. METHODS: In a randomized clinical trial, sixty patients undergoing open cholecystectomy were randomized into two groups. Before anesthesia induction, Diclofenac suppository (100 mg) and oral Clonidine (0...
2012: Journal of Cardiovascular and Thoracic Research
https://www.readbyqxmd.com/read/24030782/intravenous-lidocaine-for-post-operative-pain-relief-after-hand-assisted-laparoscopic-colon-surgery-a-randomized-placebo-controlled-clinical-trial
#12
RANDOMIZED CONTROLLED TRIAL
R Tikuišis, P Miliauskas, N E Samalavičius, A Žurauskas, R Samalavičius, V Zabulis
BACKGROUND: Perioperative intravenous (IV) infusion of lidocaine has been shown to decrease post-operative pain, shorten time to return of bowel function, and reduce the length of hospital stay. This randomized, prospective, double-blinded, placebo-controlled clinical trial evaluated the impact of IV lidocaine on the quality of post-operative analgesia and other outcomes after hand-assisted laparoscopic colon surgery. METHODS: Sixty four patients with colon cancer scheduled for elective colon resection were involved in this study...
April 2014: Techniques in Coloproctology
https://www.readbyqxmd.com/read/23455386/efficacy-of-direct-arthroscopy-guided-suprascapular-nerve-block-after-arthroscopic-rotator-cuff-repair-a-prospective-randomized-study
#13
RANDOMIZED CONTROLLED TRIAL
Jae Jun Lee, Yon-Sik Yoo, Jung-Taek Hwang, Do-Young Kim, Seong-Jae Jeon, Sung Mi Hwang, Ji Su Jang
PURPOSE: The purpose of this study was to evaluate the outcomes of arthroscopy-guided direct suprascapular nerve block performed after arthroscopic rotator cuff repair. METHODS: In the present prospective, randomized, double-blinded clinical study, 30 patients were divided into two groups: 15 patients (group I) were treated with arthroscopy-guided suprascapular nerve block using 10 mL 0.5 % ropivacaine with 1:200,000 epinephrine, and 15 patients (group II) were treated with placebo using 10 mL 0...
February 2015: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/23448586/a-2013-updated-systematic-review-meta-analysis-of-36-randomized-controlled-trials-no-apparent-effects-of-non-steroidal-anti-inflammatory-agents-on-the-risk-of-bleeding-after-tonsillectomy
#14
REVIEW
L Riggin, J Ramakrishna, D D Sommer, G Koren
BACKGROUND: Although the literature suggests that non-steroidal anti-inflammatory drugs (NSAIDs) are effective in controlling post-operative pain in the paediatric population, physicians have been reluctant to utilise these medications after tonsillectomy due to concerns of increased bleeding rates. While many surgeons prescribe opioid analgesics postoperatively, these are associated with a number of potential adverse side-effects including nausea, vomiting, constipation, excessive sedation and respiratory compromise...
April 2013: Clinical Otolaryngology
https://www.readbyqxmd.com/read/23377862/gabapentin-reduces-preoperative-anxiety-and-pain-catastrophizing-in-highly-anxious-patients-prior-to-major-surgery-a-blinded-randomized-placebo-controlled-trial
#15
RANDOMIZED CONTROLLED TRIAL
Hance Clarke, Kyle R Kirkham, Beverley A Orser, Rita Katznelson, Nicholas Mitsakakis, Raynauld Ko, Adam Snyman, Martin Ma, Joel Katz
INTRODUCTION: Gabapentin is increasingly being used for the treatment of postoperative pain and a variety of psychiatric diseases, including chronic anxiety disorders. Trials have reported mixed results when gabapentin has been administered for the treatment of preoperative anxiety. We tested the hypothesis that gabapentin 1,200 mg vs placebo would reduce preoperative anxiety in patients who exhibit moderate to high preoperative anxiety. METHODS: A blinded randomized controlled trial was conducted from September 2009 to June 2011 at the Toronto General Hospital...
May 2013: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/22826766/preoperative-topical-diclofenac-and-ketorolac-in-prevention-of-pain-and-discomfort-following-photorefractive-keratectomy-a-randomized-double-masked-placebo-controlled-clinical-trial
#16
Hassan Razmju, Ahmadreza Khalilian, Alireza Peyman, Seyed-Hossein Abtahi, Mohammad-Ali Abtahi, Mojtaba Akbari, Leyli Sadri
OBJECTIVES: To compare the efficacy of a single dose of topical diclofenac 0.1% and ketorolac 0.5%, with placebo and with each other in the prevention of post-PRK pain and discomfort. METHODS: In this randomized double-masked trial, adults undergoing bilateral PRK surgery were assigned to two arms. The first arm received a single dose diclofenac 0.1%, randomly in either the right, or left eye, and artificial tear (as the placebo) in the other eye. The second arm received ketorolac 0...
March 2012: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/22701203/pre-treatment-with-intravenous-granisetron-to-alleviate-pain-on-propofol-injection-a-double-blind-randomized-controlled-trial
#17
Ahsan Ahmed, Saikat Sengupta, Tanmoy Das, Amitava Rudra, Asif Iqbal
BACKGROUND: Propofol is one of the widely used intravenous (i.v.) anaesthetics, although pain on injection still remains a considerable concern for the anaesthesiologists. A number of techniques has been tried to minimize propofol-induced pain with variable results. Recently, a 5-HT(3) antagonist, ondansetron pre-treatment, has been shown to reduce propofol-induced pain. The aim of our randomized, placebo-controlled, double-blinded study was to determine whether pre-treatment with intravenous granisetron, which is routinely used in our practice for prophylaxis of post-operative nausea and vomiting, would reduce propofol-induced pain...
March 2012: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/21959624/oxycodone-and-dexamethasone-for-pain-management-after-tonsillectomy-a-placebo-controlled-emg-assessed-clinical-trial
#18
RANDOMIZED CONTROLLED TRIAL
Michael Vaiman, Daniel Krakovski, Zoe Haitov
BACKGROUND: Surface electromyographic (sEMG) study of post-tonsillectomy swallow-evoked muscular reactions was performed in order to evaluate the efficacy and safety of oxycodone and dexamethasone in pain management after tonsillectomy. MATERIAL/METHODS: 90 randomly chosen operated adults were divided into three groups. Group 1 (n = 30) was treated with OxyContin (Oxycodone) injections; Group 2 (n = 30) was treated with Dexacort (Dexamethasone), and Group 3 (n = 30) was a placebo group...
October 2011: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/21470320/comparison-of-pre-emptive-ibuprofen-paracetamol-and-placebo-administration-in-reducing-post-operative-pain-in-primary-tooth-extraction
#19
RANDOMIZED CONTROLLED TRIAL
Ozgul Baygin, Tamer Tuzuner, Berrin Isik, Adem Kusgoz, Mehmet Tanriver
BACKGROUND: This study investigates preliminary investigations that a pre-emptive analgesia administration may reduce post-extraction pain. AIM: This prospective, placebo-controlled, randomized, double-blind trial was planned to compare the efficacy of the pre-emptive administration of ibuprofen, paracetamol, and placebo in reducing post-extraction pain in children. DESIGN: Forty-five children, ages 6-12, who needed primary mandibular molar tooth extraction were treated in paediatric dental clinics, with treatment preceded by local anaesthesia and analgesic drugs during the preoperative period...
July 2011: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/21412134/electromyographic-assessment-of-dexamethasone-in-treatment-of-post-tonsillectomy-pain-randomized-placebo-controlled-trial
#20
RANDOMIZED CONTROLLED TRIAL
Michael Vaiman, Eliad Aviram, Daniel Krakovski, Haim Gavriel, Ephraim Eviatar
INTRODUCTION: Surface electromyographic (sEMG) study of post-tonsillectomy swallow-evoked muscular reactions was performed to assess analgesic properties of dexamethasone. METHODS: Sixty randomly chosen operated adults were divided into 2 groups. Group 1 (n = 30) was treated with dexamethasone (Dexacort, 20 mg); group 2 (n = 30) was treated with placebo. Pain assessment included visual analogue scale (VAS) pain score and the EMG data such as the timing, electric amplitude and graphic patterns of muscular activity during deglutition...
June 2011: American Journal of the Medical Sciences
keyword
keyword
72891
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"