Alejandra Padua-Bracho, José A Velázquez-Aragón, Verónica Fragoso-Ontiveros, Paulina María Nuñez-Martínez, María de la Luz Mejía Aguayo, Yuliana Sánchez-Contreras, Miguel Angel Ramirez-Otero, Marcela Angélica De la Fuente-Hernández, Silvia Vidal-Millán, Talia Wegman-Ostrosky, Abraham Pedroza-Torres, Cristian Arriaga-Canon, Luis A Herrera-Montalvo, Rosa Maria Alvarez-Gómez
Lynch syndrome (LS) is the main hereditary colorectal cancer syndrome. There have been few reports regarding the clinical and molecular characteristics of LS patients in Latin America; this is particularly true in the Mexican population, where no information is available. The present study aims to describe the clinical and molecular spectrum of variants in a cohort of patients diagnosed with LS in Mexico. We present a retrospective analysis of 412 patients with suspected LS, whose main site of cancer diagnosis was the colon (58...
September 30, 2022: International Journal of Molecular Sciences