Pragati V Prasad, Molly K Steele, Carrie Reed, Lauren Ancel Meyers, Zhanwei Du, Remy Pasco, Jorge A Alfaro-Murillo, Bryan Lewis, Srinivasan Venkatramanan, James Schlitt, Jiangzhuo Chen, Mark Orr, Mandy L Wilson, Stephen Eubank, Lijing Wang, Matteo Chinazzi, Ana Pastore Y Piontti, Jessica T Davis, M Elizabeth Halloran, Ira Longini, Alessandro Vespignani, Sen Pei, Marta Galanti, Sasikiran Kandula, Jeffrey Shaman, David J Haw, Nimalan Arinaminpathy, Matthew Biggerstaff
When an influenza pandemic emerges, temporary school closures and antiviral treatment may slow virus spread, reduce the overall disease burden, and provide time for vaccine development, distribution, and administration while keeping a larger portion of the general population infection free. The impact of such measures will depend on the transmissibility and severity of the virus and the timing and extent of their implementation. To provide robust assessments of layered pandemic intervention strategies, the Centers for Disease Control and Prevention (CDC) funded a network of academic groups to build a framework for the development and comparison of multiple pandemic influenza models...
July 11, 2023: Proceedings of the National Academy of Sciences of the United States of America