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Gynecology Emergency

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https://www.readbyqxmd.com/read/28538495/committee-opinion-no-701-choosing-the-route-of-hysterectomy-for-benign-disease
#1
(no author information available yet)
Hysterectomy is one of the most frequently performed surgical procedures in the United States. Selection of the route of hysterectomy for benign causes can be influenced by the size and shape of the vagina and uterus; accessibility to the uterus; extent of extrauterine disease; the need for concurrent procedures; surgeon training and experience; average case volume; available hospital technology, devices, and support; whether the case is emergent or scheduled; and preference of the informed patient. Vaginal and laparoscopic procedures are considered "minimally invasive" surgical approaches because they do not require a large abdominal incision and, thus, typically are associated with shortened hospitalization and postoperative recovery times compared with open abdominal hysterectomy...
June 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28516847/who-is-at-risk-for-intimate-partner-violence-victimization-using-latent-class-analysis-to-explore-interpersonal-polyvictimization-and-polyperpetration-among-pregnant-young-couples
#2
Tiara C Willie, Adeya Powell, Jessica Lewis, Tamora Callands, Trace Kershaw
The purpose of our study was (a) to use latent class analyses to identify subgroups of interpersonal polyvictimizationand polyperpetration among young pregnant couples and (b) examine actor-partner effects of latent classes on current intimate partner violence (IPV) victimization. Data were collected from 296 pregnant young couples recruited at obstetrics and gynecology clinics. A 3-latent class model emerged for women: Polyvictim-Polyperpetrator, Nonvictim-Nonperpetrator, and Community and Prior IPV Victim...
May 17, 2017: Violence and Victims
https://www.readbyqxmd.com/read/28498004/a-sequential-implementation-model-for-workforce-development-a-case-study-of-medical-residency-training-for-substance-use-concerns
#3
Patricia S O'Sullivan, Patrick Yuan, Derek D Satre, Maria Wamsley, Jason Satterfield
PROBLEM: In graduate medical education, residency programs are often educationally isolated from each other, with varying needs and patient populations, so strategies are needed when attempting to implement training in evidence-based practices across multiple residencies. INTERVENTION: Using implementation science as a guide, we adapted a community development model to sequentially implement an evidence-based intervention, Screening, Brief Intervention, and Referral to Treatment (SBIRT) for alcohol and drug use problems, across internal medicine, pediatrics, emergency medicine, psychiatry, and obstetrics and gynecology residency programs...
May 12, 2017: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/28493635/the-double-edged-experience-of-healthcare-encounters-among-women-with-endometriosis-a-qualitative-study
#4
Hanna Grundström, Siw Alehagen, Preben Kjølhede, Carina Berterö
AIMS AND OBJECTIVES: to identify and describe the experience of healthcare encounters among women with endometriosis. BACKGROUND: Endometriosis is a "hidden" chronic gynecological disease appearing in every 10(th) woman of fertile age. Different manifestations of pain are the main symptoms, often leading to impaired physical and mental health, and lower quality of life. Previous research on healthcare experiences among women with endometriosis has focused on diagnostic delay and experiences of encountering general practitioners...
May 11, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28460554/serum-levels-and-apai-polymorphism-of-insulin-like-growth-factor-2-on-intrauterine-growth-restriction-infants
#5
Monica G Hăşmăşanu, Melinda Baizat, Lucia Maria Procopciuc, Ligia Blaga, Mădălina A Văleanu, Tudor C Drugan, Gabriela C Zaharie, Sorana D Bolboacă
PURPOSE: The aim of our study was to evaluate the IGF2 and IGF2R plasmatic level and IGF2-ApaI polymorphism on infants with intrauterine growth restriction (IUGR). MATERIALS AND METHODS: A transversal study was conducted at the Neonatology Ward of the Gynecology Clinic I, Emergency Hospital Cluj-Napoca on neonates with IUGR who were discharged during June 2014 and June 2015. The serum levels of IGF2 and IGF2R were obtained by using ELISA method and IGF2-ApaI polymorphism by taking PCR-RFLP analysis...
May 1, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28459207/beyond-circulating-microrna-biomarkers-urinary-micrornas-in-ovarian-and-breast-cancer
#6
Maria Luisa Gasparri, Assunta Casorelli, Erlisa Bardhi, Aris Raad Besharat, Delia Savone, Ilary Ruscito, Ammad Ahmad Farooqi, Andrea Papadia, Michael David Mueller, Elisabetta Ferretti, Pierluigi Benedetti Panici
Breast cancer is the most common malignancy in women worldwide, and ovarian cancer is the most lethal gynecological malignancy. Women carrying a BRCA1/2 mutation have a very high lifetime risk of developing breast and ovarian cancer. The only effective risk-reducing strategy in BRCA-mutated women is a prophylactic surgery with bilateral mastectomy and bilateral salpingo-oophorectomy. However, many women are reluctant to undergo these prophylactic surgeries due to a consequent mutilated body perception, unfulfilled family planning, and precocious menopause...
May 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28442420/eggerthella-lenta-bacteremia-in-solid-tumor-cancer-patients-pathogen-or-witness-of-frailty
#7
Paul-Louis Woerther, Sami Antoun, Elisabeth Chachaty, Mansouria Merad
Eggerthella lenta is increasingly found in patients with severe comorbidities. Because oncologic patients are exposed to emerging pathogens, we aimed to describe the factors associated with E. lenta bacteremia in this immunosuppressed population. Oncology patients with blood cultures positive for E. lenta were retrospectively recorded from 2009 to 2015. Socio-demographic and medical/biological data as well as potential risk factors and mortality were recorded and analyzed. Twenty-three patients were included...
April 22, 2017: Anaerobe
https://www.readbyqxmd.com/read/28433870/automated-detection-of-premature-delivery-using-empirical-mode-and-wavelet-packet-decomposition-techniques-with-uterine-electromyogram-signals
#8
U Rajendra Acharya, Vidya K Sudarshan, Soon Qing Rong, Zechariah Tan, Choo Min Lim, Joel Ew Koh, Sujatha Nayak, Sulatha V Bhandary
An accurate detection of preterm labor and the risk of preterm delivery before 37 weeks of gestational age is crucial to increase the chance of survival rate for both mother and the infant. Thus, the uterine contractions measured using uterine electromyogram (EMG) or electro hysterogram (EHG) need to have high sensitivity in the detection of true preterm labor signs. However, visual observation and manual interpretation of EHG signals at the time of emergency situation may lead to errors. Therefore, the employment of computer-based approaches can assist in fast and accurate detection during the emergency situation...
April 18, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28414551/long-noncoding-rna-mnx1-as1-knockdown-inhibits-cell-proliferation-and-migration-in-ovarian-cancer
#9
Yan Lv, Huan Li, Fengling Li, Peishu Liu, Xinrui Zhao
Long noncoding RNAs (lncRNAs) have recently emerged as pivotal regulators that govern fundamental biological processes and disease pathogenesis. LncRNA MNX1-AS1 has been reported to promote cell proliferation and invasion in gallbladder cancer, but its biological role and regulatory mechanism in ovarian cancer are poorly defined. In this study, it was found that higher expression of lncRNA MNX1-AS1 is closely associated with International Federation of Gynecology and Obstetrics stage and lymphatic metastasis in ovarian cancer patients...
April 2017: Cancer Biotherapy & Radiopharmaceuticals
https://www.readbyqxmd.com/read/28409048/laparoscopic-reduction-and-closure-of-an-internal-hernia-secondary-to-gynecologic-surgery
#10
Takashi Sakamoto, Alan Kawarai Lefor
Internal hernia is a rare cause of bowel obstruction which often requires emergent surgery. In general, the preoperative diagnosis of internal hernia is difficult. The pelvic cavity has various spaces with the potential to result in a hernia, especially in females. In this report, we describe a patient with an internal hernia secondary to previous gynecologic surgery. A 49-year-old woman presented with acute abdominal pain and a history of previous right oophorectomy for a benign ovarian cyst. Computed tomography scan of the abdomen showed obstruction with strangulation and emergent laparoscopic exploration was performed...
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/28401127/diagnostic-and-referral-intervals-for-manitoba-women-with-epithelial-ovarian-cancer-the-manitoba-ovarian-cancer-outcomes-moco-study-group-a-retrospective-cross-sectional-study
#11
Allison J Love, Pascal Lambert, Donna Turner, Robert Lotocki, Erin Dean, Shaundra Popowich, Alon D Altman, Mark W Nachtigal
BACKGROUND: Epithelial ovarian cancer has the highest mortality of all gynecologic cancers. The poor survival rates are often attributed to the advanced stage at which most of these cancers are detected. We sought to examine the effects of patient demographics, comorbidities and presenting symptoms on diagnostic and referral intervals by location of first presentation (emergency department v. elsewhere) and to identify factors that affect these intervals. METHODS: We performed a retrospective analysis of chart and medical record data for ovarian cancers, with the exceptions of sex cord and germ cell tumours, diagnosed between 2004 and 2010 in Manitoba, Canada...
January 2017: CMAJ Open
https://www.readbyqxmd.com/read/28392498/magnesium-in-the-gynecological-practice-a-literature-review
#12
Fabio Parazzini, Mirella Di Martino, Paolo Pellegrino
A growing amount of evidence suggests that magnesium deficiency may play an important role in several clinical conditions concerning women health such as premenstrual syndrome, dysmenorrhea, and postmenopausal symptoms. A number of studies highlighted a positive correlation between magnesium administration and relief or prevention of these symptoms, thus suggesting that magnesium supplementation may represent a viable treatment for these conditions. Despite this amount of evidence describing the efficacy of magnesium, few and un-systematize data are available about the pharmacological mechanism of this ion for these conditions...
April 6, 2017: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/28367839/developing-a-checklist-for-collecting-information-from-overseas-hospitals
#13
Juri Matsuoka, Yuichi Kobayashi, Shigeyuki Kajiki, Masamichi Uehara, Norio Sasaki, Kiminori Odagami, Kou Hiraoka, Shigemoto Nakanishi, Yu Igarashi, Koji Mori
OBJECTIVE: Expatriate workers and their families may encounter difficulties and uncertainties when visiting local hospitals. These problems include differences in the medical system, higher healthcare costs, and language problems. Occupational health staff in companies need to know about the healthcare system, including emergency transportation arrangements, to reduce anxiety in workers and families attending hospitals. This study was designed to create a checklist to allow occupational health staff to collect information from overseas hospitals efficiently and effectively...
March 31, 2017: Sangyō Eiseigaku Zasshi, Journal of Occupational Health
https://www.readbyqxmd.com/read/28333243/polycystic-ovary-syndrome-is-associated-with-anogenital-distance-a-marker-of-prenatal-androgen-exposure
#14
Yingchen Wu, Guangzheng Zhong, Shengfu Chen, Chengyu Zheng, Dehua Liao, Meiqing Xie
STUDY QUESTION: Is the presence of polycystic ovary syndrome (PCOS) associated with anogenital distance (AGD), a biomarker for the prenatal hormonal environment? SUMMARY ANSWER: The presence of PCOS is associated with longer AGD. WHAT IS KNOWN ALREADY: Although the aetiology of PCOS is unclear, emerging data suggest that the natural history of PCOS may originate from intrauterine life. Prenatal exposure to androgen hormones is considered an important factor of PCOS...
April 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28290956/multidisciplinary-in-situ-simulation-based-training-as-a-postpartum-hemorrhage-quality-improvement-project
#15
Monica A Lutgendorf, Carmen Spalding, Elizabeth Drake, Dennis Spence, Jason O Heaton, Kristina V Morocco
BACKGROUND: Postpartum hemorrhage is a common obstetric emergency affecting 3 to 5% of deliveries, with significant maternal morbidity and mortality. Effective management of postpartum hemorrhage requires strong teamwork and collaboration. We completed a multidisciplinary in situ postpartum hemorrhage simulation training exercise with structured team debriefing to evaluate hospital protocols, team performance, operational readiness, and real-time identification of system improvements...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28286604/a-review-of-mtor-pathway-inhibitors-in-gynecologic-cancer
#16
REVIEW
Andréia Cristina de Melo, Eduardo Paulino, Álvaro Henrique Ingles Garces
The treatment of advanced gynecologic cancers remains palliative in most of cases. Although systemic treatment has entered into the era of targeted drugs the antitumor efficacies of current therapies are still limited. In this context there is a great need for more active treatment and rationally designed targeted therapies. The PI3K/AKT/mTOR is a signaling pathway in mammal cells that coordinates important cell activities. It has a critical function in the survival, growth, and proliferation of malignant cells and was object of important research in the last two decades...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28282875/a-perspective-on-ovarian-cancer-biomarkers-past-present-and-yet-to-come
#17
Frederick R Ueland
The history of biomarkers and ultrasonography dates back over more than 50 years. The present status of biomarkers used in the context of ovarian cancer is addressed. Attention is given to new interpretations of the etiology of ovarian cancer. Cancer antigen 125 (CA125) and multivariate index assays (Ova1, Risk of Ovarian Malignancy Algorithm, Overa) are biomarker-driven considerations that are presented. Integration of biomarkers into ovarian cancer diagnostics and screening are presented in conjunction with ultrasound...
March 8, 2017: Diagnostics
https://www.readbyqxmd.com/read/28277591/the-role-of-fluorescent-angiography-in-anastomotic-leaks
#18
Sarath Sujatha-Bhaskar, Mehraneh D Jafari, Michael J Stamos
Anastomotic leaks following colorectal anastomosis has substantial implications including increased morbidity, longer hospitalization, and reduced overall survival. The etiology of leaks includes patient factors, technical factors, and anastomotic perfusion. An intact anastomotic blood supply is especially crucial in the physiology of anastomotic healing. To date, no established intraoperative methods have been developed that reliably and reproducibly identify and prevent leak occurrence. Recently, fluorescent angiography (FA) with indocyanine green (ICG) has emerged as an innovative modality for intraoperative perfusion assessment...
March 9, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28258747/psychotherapy-with-somatosensory-stimulation-for-endometriosis-associated-pain-the-role-of-the-anterior-hippocampus
#19
Florian Beissner, Christine Preibisch, Annemarie Schweizer-Arau, Roxana M Popovici, Karin Meissner
BACKGROUND: Endometriosis is a gynecological disorder affecting 6%-10% of all women in their reproductive age. There is an emerging view in the literature that psychological trauma plays a central role in the pathogenesis of pelvic pain, one of the core symptoms of endometriosis. Here we report central nervous system mechanisms of a novel combination of psychotherapy and somatosensory stimulation that has recently shown remarkable effects in reducing pain, anxiety, and depressive symptoms in these patients...
January 16, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/28257538/multidisciplinary-approach-to-complicated-pregnancy
#20
Josip Andelo Borovac, Josko Bozic, Tina Ticinovic Kurir, Nikola Zaja, Kresimir Kolic, Vedran Hrboka
A nulliparous pregnant woman in her mid-20s and in the 32nd week of gestation presented to the emergency department with severe headache and vomiting. She had an uneventful medical history; however, the physical examination upon hospital admission revealed a hypertensive emergency, papilledema, and 2+ dipstick proteinuria. Upon establishing the diagnosis of preeclampsia, aggressive therapy with corticosteroids, antihypertensive medication, and seizure prophylaxis was initiated. Hemodynamic stability was achieved within 24 hours and the patient remained in the observation unit located within the gynecology clinic...
March 2017: Southern Medical Journal
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