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https://www.readbyqxmd.com/read/28550367/in-vitro-study-of-antioxidant-and-antibacterial-activities-of-lactobacillus-probiotic-spp
#1
Z Pourramezan, R Kasra Kermanshahi, M Oloomi, A Aliahmadi, H Rezadoost
This study investigated the influence of aeration and minimal medium conditions on antioxidant and antibacterial activities of 21 probiotic Lactobacillus strains isolated from dairy products. The probiotic potential of the isolates was evaluated by pH and bile tolerance. Random amplified polymorphic DNA polymerase chain reaction (RAPD-PCR) was used to confirm the phenotypic identification of isolates. Antioxidant producer isolates were screened by resistance to reactive oxygen species (ROS). The antioxidant and antibacterial activities of extracellular materials after 48 h fermentation with antioxidative strains were determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and broth microdilution assays, respectively...
May 26, 2017: Folia Microbiologica
https://www.readbyqxmd.com/read/28549804/the-efficient-clade-lactic-acid-bacteria-for-industrial-chemical-production
#2
REVIEW
Michael Sauer, Hannes Russmayer, Reingard Grabherr, Clemens K Peterbauer, Hans Marx
Lactic acid bacteria are well known to be beneficial for food production and, as probiotics, they are relevant for many aspects of health. However, their potential as cell factories for the chemical industry is only emerging. Many physiological traits of these microorganisms, evolved for optimal growth in their niche, are also valuable in an industrial context. Here, we illuminate these features and describe why the distinctive adaptation of lactic acid bacteria is particularly useful when developing a microbial process for chemical production from renewable resources...
May 23, 2017: Trends in Biotechnology
https://www.readbyqxmd.com/read/28546539/microbiota-modulation-counteracts-alzheimer-s-disease-progression-influencing-neuronal-proteolysis-and-gut-hormones-plasma-levels
#3
Laura Bonfili, Valentina Cecarini, Sara Berardi, Silvia Scarpona, Jan S Suchodolski, Cinzia Nasuti, Dennis Fiorini, Maria Chiara Boarelli, Giacomo Rossi, Anna Maria Eleuteri
Gut microbiota has a proven role in regulating multiple neuro-chemical pathways through the highly interconnected gut-brain axis. Oral bacteriotherapy thus has potential in the treatment of central nervous system-related pathologies, such as Alzheimer's disease (AD). Current AD treatments aim to prevent onset, delay progression and ameliorate symptoms. In this work, 3xTg-AD mice in the early stage of AD were treated with SLAB51 probiotic formulation, thereby affecting the composition of gut microbiota and its metabolites...
May 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28546485/draft-genome-sequence-of-magnesium-dissolving-lactococcus-garvieae-a1-isolated-from-soil
#4
Gonca Altın, Emrah Nikerel, Fikrettin Şahin
The probiotic bacterium Lactococcus garvieae A1, isolated from soil, is interesting for biomining applications. Here, we report the draft genome sequence and annotation of this strain, with a focus on metal transporter enzymes.
May 25, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28546425/the-first-crystal-structure-of-a-family-129-glycoside-hydrolase-from-a-probiotic-bacterium-reveals-critical-residues-and-metal-co-factors
#5
Mayo Sato, Dorothee Liebschner, Yusuke Yamada, Naohiro Matsugaki, Takatoshi Arakawa, Siobhan S Wills, Mitchell Hattie, Keith A Stubbs, Tasuku Ito, Toshiya Senda, Hisashi Ashida, Shinya Fushinobu
The α-N-acetylgalactosaminidase from the probiotic bacterium Bifidobacterium bifidum (NagBb) belongs to the glycoside hydrolase (GH) family 129 and hydrolyzes the glycosidic bond of Tn antigen (GalNAcα1-Ser/Thr). NagBb is involved in assimilation of O-glycans on mucin glycoproteins by B. bifidum in the human gastrointestinal tract, but its catalytic mechanism has remained elusive because of a lack of sequence homology around putative catalytic residues and of other structural information. Here we report the X-ray crystal structure of NagBb, representing the first GH129 family structure, solved by the single-wavelength anomalous dispersion method based on sulfur atoms of the native protein...
May 25, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28545241/lactobacillus-rhamnosus-hn001-and-lactobacillus-acidophilus-la-14-attenuate-gardnerella-vaginalis-infected-bacterial-vaginosis-in-mice
#6
Se-Eun Jang, Jin-Ju Jeong, Su-Young Choi, Hyunji Kim, Myung Joo Han, Dong-Hyun Kim
Oral administration of a probiotic mixture (PM; Respecta(®)) consisting of Lactobacillus rhamnosus HN001 (L1), Lactobacillus acidophilus La-14 (L2), and lactoferrin RCXTM results in colonization of these probiotics in the vagina of healthy women. Therefore, we examined whether vaginal colonization of the PM ingredients L1 and L2 could attenuate bacterial vaginosis (BV). BV was induced in mice via β-estradiol-3-benzoate-induced immunosuppression and intravaginal inoculation with Gardnerella vaginalis (GV)...
May 23, 2017: Nutrients
https://www.readbyqxmd.com/read/28544086/effect-of-probiotic-supplementation-and-genotype-on-growth-performance-carcass-traits-hematological-parameters-and-immunity-of-growing-rabbits-under-hot-environmental-conditions
#7
Moataz Fathi, Magdy Abdelsalam, Ibrahim Al-Homidan, Tarek Ebeid, Mohamed El-Zarei, Osama Abou-Emera
The effect of dietary inclusion of probiotics and genetic groups on rabbit performance under hot environmental conditions was studied. A total of 80 rabbits aged 8 weeks were distributed into a completely randomized design in a 4 × 3 factorial arrangement, including four genetic groups and three concentrations of dietary probiotic (0, 200 and 400 g/t feed). The utilized probiotic contained 4 × 10(9)  colony-forming units/g of Bacillus subtilis. Jabali local breed (J), imported Spanish V-line (V) and their crossbreds (¼J¾V and ¾J¼V) were included in the current study...
May 22, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/28540921/the-path-towards-microbiome-based-metabolite-treatment
#8
Jotham Suez, Eran Elinav
The increasing evidence pointing towards the involvement of the gut microbiome in multiple diseases, as well as its plasticity, renders it a desirable potential therapeutic target. Nevertheless, classical therapies based on the consumption of live probiotic bacteria, or their enrichment by prebiotics, exhibit limited efficacy. Recently, a novel therapeutic approach has been suggested based on metabolites secreted, modulated or degraded by the microbiome. As many of the host-microorganism interactions pertaining to human health are mediated by metabolites, this approach may be able to provide therapeutic efficacy while overcoming caveats of current microbiome-targeting therapies, such as colonization resistance and inter-individual variation in microbial composition...
May 25, 2017: Nature Microbiology
https://www.readbyqxmd.com/read/28539820/bifidobacterium-pseudocatenulatum-cect-7765-supplementation-restores-altered-vascular-function-in-an-experimental-model-of-obese-mice
#9
María D Mauricio, Eva Serna, María Leonor Fernández-Murga, Jesica Portero, Martín Aldasoro, Soraya L Valles, Yolanda Sanz, José M Vila
Aims.Bifidobacterium pseudocatenulatum CECT 7765 improves metabolic and immunological altered functions in high fat fed mice, however little is known about the effects of potential probiotics on vascular reactivity. The aim of the present study was to investigate the effects of a potential probiotic strain, Bifidobacterium pseudocatenulatum CECT 7765, on vascular response in obese mice. Methods. Aorta samples were obtained from mice, which were divided into three groups: a control group, receiving a standard diet; an obese group, receiving a high-fat diet; and an obese group receiving high-fat diet and a daily dose of B...
2017: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/28538869/potential-mechanisms-linking-probiotics-to-diabetes-a-narrative-review-of-the-literature
#10
Maryam Miraghajani, Somayeh Shahraki Dehsoukhteh, Nahid Rafie, Sahar Golpour Hamedani, Sima Sabihi, Reza Ghiasvand
CONTEXT AND OBJECTIVE: Some studies have suggested a wide range of possible mechanisms through which probiotics may play a role in diabetes prevention and treatment. However, the underlying mechanisms are not fully understood. We conducted this study to review the potential mechanisms suggested for the effect of probiotics in diabetes. DESIGN AND SETTING: Narrative review conducted at the Food Security Research Center of Isfahan. METHODS: A search in the electronic databases MEDLINE (PubMed), Cochrane Library, Web of Science and Google scholar was performed up to October 2016...
March 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28538366/preventing-necrotizing-enterocolitis-by-food-additives-in-neonates-a-network-meta-analysis-revealing-the-efficacy-and-safety
#11
Wentao Yu, Wu Sui, Linsong Mu, Wenying Yi, Haijuan Li, Liqin Wei, Weihong Yin
BACKGROUND: Necrotizing enterocolitis (NEC) is a serious multifactorial gastrointestinal disease which is often discovered in premature infants. Various additives have been used to prevent NEC; yet, their relative efficacy and safety remain disputed. This study aims to compare the efficacy and safety of 5 food additives, namely, probiotics, probiotics + fructo-oligosaccharides, pentoxifylline, arginine, and lactoferrin in preventing NEC in neonates. METHODS: Embase, PubMed, and Cochrane Library had been searched for all eligible randomized control trials...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28537934/alternative-treatments-for-chronic-spontaneous-urticaria-beyond-the-guideline-algorithm
#12
Gino A Vena, Marcus Maurer, Nicoletta Cassano, Torsten Zuberbier
PURPOSE OF REVIEW: The international EAACI/GALEN/EDF/WAO guideline suggests a stepwise approach for the therapeutic management of chronic spontaneous urticaria (CSU), outlined in an algorithm. The aim of this article is to summarize and review the evidence available on alternative treatment options for CSU outside of this algorithm. RECENT FINDINGS: Although CSU is a common disease, there are a limited number of high-quality studies, and only antihistamines and omalizumab are licensed for its treatment...
May 22, 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28537817/the-action-of-probiotic-microorganisms-on-chemical-contaminants-in-milk
#13
Katia Francine Wochner, Tânia Aparecida Becker-Algeri, Eliane Colla, Eliana Badiale-Furlong, Deisy Alessandra Drunkler
Consumption of milk and its derivatives is an important food habit in the diet of all age groups. However, there has been increasing concern about physical, biological (pathogenic or spoilage microorganisms) and chemical (metals, pesticides and mycotoxins) contaminants in milk and dairy products. Considering the high levels of consumption, it is important that milk and dairy products are free from toxic compounds. Microbial degradation as a strategy for chemical decontamination is an emerging biotechnological approach that is considered a safe and inexpensive practice...
May 24, 2017: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/28537581/the-effects-of-a-multispecies-probiotic-on-migraine-and-markers-of-intestinal-permeability-results-of-a-randomized-placebo-controlled-study
#14
N M de Roos, S van Hemert, J M P Rovers, M G Smits, B J M Witteman
BACKGROUND/OBJECTIVES: Migraine, associated with several gastrointestinal disorders, may result from increased intestinal permeability, allowing endotoxins to enter the bloodstream. We tested whether probiotics could reduce migraine through an effect on intestinal permeability and inflammation. SUBJECTS/METHODS: In total, 63 patients were randomly allocated to the probiotic (n=31) or the placebo group (n=32). Participants ingested a multispecies probiotic (5x10(9) colony-forming units) or placebo daily for 12 weeks...
May 24, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28536484/ibs-mindful-of-probiotics-for-psychiatric-comorbidities-in-ibs
#15
Katrina Ray
No abstract text is available yet for this article.
May 24, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28535747/in-vitro-assessment-of-pediococcus-acidilactici-kp10-for-its-potential-use-in-the-food-industry
#16
Sahar Abbasiliasi, Joo Shun Tan, Fatemeh Bashokouh, Tengku Azmi Tengku Ibrahim, Shuhaimi Mustafa, Faezeh Vakhshiteh, Subhashini Sivasamboo, Arbakariya B Ariff
BACKGROUND: Selection of a microbial strain for the incorporation into food products requires in vitro and in vivo evaluations. A bacteriocin-producing lactic acid bacterium (LAB), Pediococcus acidilactici Kp10, isolated from a traditional dried curd was assessed in vitro for its beneficial properties as a potential probiotic and starter culture. The inhibitory spectra of the bacterial strain against different gram-positive and gram-negative bacteria, its cell surface hydrophobicity and resistance to phenol, its haemolytic, amylolytic and proteolytic activities, ability to produce acid and coagulate milk together with its enzymatic characteristics and adhesion property were all evaluated in vitro...
May 23, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28534820/antioxidant-properties-of-probiotic-bacteria
#17
REVIEW
Yang Wang, Yanping Wu, Yuanyuan Wang, Han Xu, Xiaoqiang Mei, Dongyou Yu, Yibing Wang, Weifen Li
Oxidative stress defines a condition in which the prooxidant-antioxidant balance in the cell is disturbed, resulting in DNA hydroxylation, protein denaturation, lipid peroxidation, and apoptosis, ultimately compromising cells' viability. Probiotics have been known for many beneficial health effects, and the consumption of probiotics alone or in food shows that strain-specific probiotics can present antioxidant activity and reduce damages caused by oxidation. However, the oxidation-resistant ability of probiotics, especially the underling mechanisms, is not properly understood...
May 19, 2017: Nutrients
https://www.readbyqxmd.com/read/28533178/mucin-and-carbohydrate-stimulated-adhesion-and-subproteome-changes-of-the-probiotic-bacterium-lactobacillus-acidophilus-ncfm
#18
Hasan Ufuk Celebioglu, Sita Vaag Olesen, Kennie Prehn, Sampo J Lahtinen, Susanne Brix, Maher Abou Hachem, Birte Svensson
Adhesion to intestinal mucosa is a crucial property for probiotic bacteria. Adhesion is thought to increase host-bacterial interactions, thus potentially enabling health benefits to the host. Molecular events connected with adhesion and surface proteome changes were investigated for the probiotic Lactobacillus acidophilus NCFM cultured with established or emerging prebiotic carbohydrates as carbon source and in the presence of mucin, the glycoprotein of the epithelial mucus layer. Variation in adhesion to HT29-cells and mucin was associated with carbon source and mucin-induced subproteome abundancy differences...
May 19, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28532064/encapsulation-of-lactobacillus-kefiri-in-alginate-microbeads-using-a-double-novel-aerosol-technique
#19
Christian Demitri, Leonardo Lamanna, Egidio De Benedetto, Fabrizio Damiano, Maria Stella Cappello, Luisa Siculella, Alessandro Sannino
Alginate micro beads containing Lactobacillus kefiri (the principal bacteria present in the kefir probiotic drink) were produced by a novel technique based on dual aerosols spaying of alginate based solution and CaCl2 as cross linking agent. Carboxymethylcellulose (CMC) has been also added to the alginate in order to change the physic-chemical properties (viscosity and permeability) of the microbeads. Calcium alginate and CMC are biopolymers that can be used for developing oral drug-delivery systems. These biopolymers have been reported to show a pH-dependent swelling behaviour...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28531784/gut-microbiota-mediated-benefits-of-barley-kernel-products-on-metabolism-gut-hormones-and-inflammatory-markers-as-affected-by-co-ingestion-of-commercially-available-probiotics-a-randomized-controlled-study-in-healthy-subjects
#20
Anne Nilsson, Elin Johansson-Boll, Jonna Sandberg, Inger Björck
BACKGROUND AND AIMS: Barley kernel based products have been shown to induce benefits on blood glucose regulation, cardio-metabolic risk markers and appetite regulating hormones in a time perspective of 11-16 h after intake. The mechanisms have been assigned to gut fermentation of indigestible carbohydrates. The purpose of the present study was to evaluate if the modulatory effects of barley on markers of metabolic- and appetite regulation are affected by a dietary background including a mixture of commercially available probiotics...
October 2016: Clinical Nutrition ESPEN
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