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https://www.readbyqxmd.com/read/29031239/probiotic-intervention-influences-the-salivary-levels-of-matrix-metalloproteinase-mmp-9-and-tissue-inhibitor-of-metalloproteinases-timp-1-in-healthy-adults
#1
Heli Jäsberg, Taina Tervahartiala, Timo Sorsa, Eva Söderling, Anna Haukioja
OBJECTIVE: To study the effect of orally administered Bifidobacterium animalis subsp. lactis BB-12 and Lactobacillus rhamnosus GG on the salivary levels of Matrix Metalloproteinases (MMP)-8, MMP-9 and of Tissue Inhibitor of Metalloproteinases (TIMP)-1 in healthy adults. Furthermore, the correlations between MMP-8, MMP-9 and TIMP-1 and plaque and gingival indices, salivary mutans streptococci and lactobacilli counts, and stimulated saliva secretion rate were analysed. DESIGN: The salivary samples originated from a randomized controlled trial where healthy student volunteers consumed probiotic or placebo lozenges twice a day for four weeks...
October 7, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29031236/inhibitory-effect-of-probiotic-lactobacilli-supernatants-on-single-and-mixed-non-albicans-candida-species-biofilm
#2
Yulong Tan, Matthias Leonhard, Doris Moser, Su Ma, Berit Schneider-Stickler
OBJECTIVES: Oral candidiasis is one of the most common human fungal infections. While most cases of the Candida species isolated from the oral cavity are Candida albicans, a large number of candidiasis is attributed to non-albicans Candida species. In this study, we aim to evaluate the in vitro inhibition of supernatants of Lactobacillus gasseri and Lactobacillus rhamnosus on the single and mixed species biofilm of non-albicans Candida species, including Candida tropicalis, Candida krusei and Candida parapsilosis...
October 6, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29028076/intestinal-probiotics-in-relieving-clinical-symptoms-of-severe-hand-foot-and-mouth-disease-and-potential-mechanism-analysis
#3
F Zhu, Z Jiang, H-W Li
OBJECTIVE: In this prospective cohort study, the efficacy and action mechanism of an intestinal probiotic formulation, Golden Bifid, in severe hand, foot, and mouth disease (HFMD) were determined in 63 consecutively admitted patients successfully treated in the Pediatrics Emergency Department of our hospital. PATIENTS AND METHODS: All patients had a persistent fever; 43 patients had rashes on hands, feet, crissum, and hips; and 45 patients had neurological signs and symptoms...
September 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29027368/expression-of-fluorescent-proteins-in-lactobacillus-rhamnosus-to-study-host-microbe-and-microbe-microbe-interactions
#4
Irina Spacova, Elke Lievens, Tine Verhoeven, Hans Steenackers, Jos Vanderleyden, Sarah Lebeer, Mariya I Petrova
Probiotic Lactobacillus strains are widely used to benefit human and animal health, although the exact mechanisms behind their interactions with the host and the microbiota are largely unknown. Fluorescent tagging of live probiotic cells is an important tool to unravel their modes of action. In this study, the implementation of different heterologously expressed fluorescent proteins for the labelling of the model probiotic strains Lactobacillus rhamnosusGG (gastrointestinal) and Lactobacillus rhamnosusGR-1 (vaginal) was explored...
October 13, 2017: Microbial Biotechnology
https://www.readbyqxmd.com/read/29027118/genetic-variation-of-pln-loci-among-probiotic-lactobacillus-plantarum-group-strains-with-antioxidant-and-cholesterol-lowering-ability
#5
Sundru Manjulata Devi, Prakash M Halami
In the present study, 14 different plantaricin-encoding genes of pln loci were studied and compared to available sequences from public domain database of probiotic Lactobacillus plantarum strains. Based upon the presence and absence of selected genes, pln locus was grouped into eight clusters. Further, quantitative real-time PCR (qRT-PCR) analysis for seven genes has discriminated the complex pln locus into five types which includes WCFS1 (in Lactobacillus plantarum subsp. plantarum MCC 2976 and MCC 2974 and Lactobacillus paraplantarum MCC 2978), closely related to J51 (in Lb...
October 13, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29026729/probiotics-in-children-what-is-the-evidence
#6
REVIEW
Iva Hojsak
The number of papers discussing probiotics increases tremendously that limits the possibility for primary care physicians and clinicians to stay updated. Therefore, the aim of this paper will be to summarize available evidence of probiotic use in well-defined clinical indications of importance for pediatricians. Based on currently available evidence certain probiotic strains (Lactobacillus rhamnosus GG [LGG] and Saccharomyces boulardii) have proven effect in the treatment of acute gastroenteritis and prevention of antibiotic associated diarrhea...
September 2017: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/29026695/comparison-between-antibacterial-effect-of-chlorhexidine-0-2-and-different-concentrations-of-cyperus-rotundus-extract-an-in-vitro-study
#7
Roza Haghgoo, Majid Mehran, Hamideh Farajian Zadeh, Elaheh Afshari, Nafiseh Farajian Zadeh
AIMS AND OBJECTIVES: Modern methods of caries prevention concentrated on natural ingredients usage such as probiotics and polyphenols that are safer for young children with Streptococcus mutans inhibitory properties. The purpose of this study was to compare antibacterial effects of different concentration of Cyperus rotundus extract and chlorhexidine (CHX) 0.2% mouthwash on S. mutans and Lactobacillus acidophilus. MATERIALS AND METHODS: In this in vitro study, the antibacterial effectiveness of the C...
September 2017: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/29026656/phylogenomics-and-comparative-genomics-of-lactobacillus-salivarius-a-mammalian-gut-commensal
#8
Hugh M B Harris, Maxence J B Bourin, Marcus J Claesson, Paul W O'Toole
The genus Lactobacillus is a diverse group with a combined species count of over 200. They are the largest group within the lactic acid bacteria and one of the most important bacterial groups involved in food microbiology and human nutrition because of their fermentative and probiotic properties. Lactobacillus salivarius, a species commonly isolated from the gastrointestinal tract of humans and animals, has been described as having potential probiotic properties and results of previous studies have revealed considerable functional diversity existing on both the chromosomes and plasmids...
August 2017: Microbial Genomics
https://www.readbyqxmd.com/read/29026199/probiotic-supplementation-in-preterm-infants-does-not-affect-the-risk-of-retinopathy-of-prematurity-a-meta-analysis-of-randomized-controlled-trials
#9
Giacomo Cavallaro, Eduardo Villamor-Martínez, Luca Filippi, Fabio Mosca, Eduardo Villamor
Retinopathy of prematurity (ROP) is a vascular disorder of the developing retina in preterm infants and is a leading cause of childhood blindness. Perinatal infection plays a pathogenic role in ROP. Probiotic supplementation reduces the risk of late onset sepsis (LOS) in preterm infants but it remains to be determined whether this reduction translates into a reduction of other complications. We conducted a systematic review and meta-analysis to evaluate the possible role of probiotics in altering the risk of ROP...
October 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29024599/the-effects-of-combined-probiotic-ingestion-and-circuit-training-on-muscular-strength-and-power-and-cytokine-responses-in-young-males
#10
Nur Syazwani Ibrahim, Ayu Suzailiana Muhamad, Foong Kiew Ooi, Jamaayah Meor-Osman, Chee Keong Chen
To our knowledge, the efficacy of combined probiotic supplementation with circuit training has not been evaluated. Thus, we investigated the effects of probiotic supplementation combined with circuit training on isokinetic muscular strength and power and cytokine responses in young males. Forty-eight healthy sedentary young males were recruited and randomised into four separate groups: sedentary placebo control (C), probiotics (P), circuit training with placebo (CT), and circuit training with probiotics (CTP)...
October 12, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29023714/in-vitro-assessment-of-bioactivities-of-lactobacillus-strains-as-potential-probiotics-for-humans-and-chickens
#11
P Shokryazdan, M F Jahromi, J B Liang, C C Sieo, R Kalavathy, Z Idrus, Y W Ho
Twelve previously isolated Lactobacillus strains were investigated for their in vitro bioactivities, including bile salt hydrolase (BSH), cholesterol-reducing and antioxidant activities, cytotoxic effects against cancer cells, enzyme activity, and biogenic amine production. Among them, only 4 strains showed relatively high BSH activity, whereas the rest exhibited low BSH activity. All 12 strains showed cholesterol-reducing and antioxidant activities, especially in their intact cells, which in most of the cases, the isolated strains were stronger in these activities than the tested commercial reference strains...
October 12, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/29023454/antifungal-defense-of-probiotic-lactobacillus-rhamnosus-gg-is-mediated-by-blocking-adhesion-and-nutrient-depletion
#12
Daniela Mailänder-Sánchez, Christina Braunsdorf, Christian Grumaz, Christoph Müller, Stefan Lorenz, Philip Stevens, Jeanette Wagener, Betty Hebecker, Bernhard Hube, Franz Bracher, Kai Sohn, Martin Schaller
Candida albicans is an inhabitant of mucosal surfaces in healthy individuals but also the most common cause of fungal nosocomial blood stream infections, associated with high morbidity and mortality. As such life-threatening infections often disseminate from superficial mucosal infections we aimed to study the use of probiotic Lactobacillus rhamnosus GG (LGG) in prevention of mucosal C. albicans infections. Here, we demonstrate that LGG protects oral epithelial tissue from damage caused by C. albicans in our in vitro model of oral candidiasis...
2017: PloS One
https://www.readbyqxmd.com/read/29023420/probiotics-for-the-prevention-of-antibiotic-associated-diarrhea-in-outpatients-a-systematic-review-and-meta-analysis
#13
REVIEW
Sara Blaabjerg, Daniel Maribo Artzi, Rune Aabenhus
A common adverse effect of antibiotic use is diarrhea. Probiotics are living microorganisms, which, upon oral ingestion, may prevent antibiotic-associated diarrhea (AAD) by the normalization of an unbalanced gastrointestinal flora. The objective of this systematic review was to assess the benefits and harms of probiotics used for the prevention of AAD in an outpatient setting. A search of the PubMed database was conducted and yielded a total of 17 RCTs with 3631 participants to be included in the review. A meta-analysis was conducted for the primary outcome: the incidence of AAD...
October 12, 2017: Antibiotics
https://www.readbyqxmd.com/read/29023393/flavanol-rich-cocoa-powder-interacts-with-lactobacillus-rhamnossus-lgg-to-alter-the-antibody-response-to-infection-with-the-parasitic-nematode-ascaris-suum
#14
Saebyeol Jang, Sukla Lakshman, Ethiopia Beshah, Yue Xie, Aleksey Molokin, Bryan T Vinyard, Joseph F Urban, Cindy D Davis, Gloria I Solano-Aguilar
Consumption of the probiotic bacteria LactobacillusrhamnosusLGG and flavanol-rich cocoa have purported immune modulating effects. This study compared the host response to infection with Ascaris suum in three-month-old pigs fed a standard growth diet supplemented with a vehicle control: LGG, cocoa powder (CP) or LGG + CP. Pigs were inoculated with infective A. suum eggs during Week 5 of dietary treatment and euthanized 17 days later. Lactobacillus abundance was increased in pigs fed LGG or LGG + CP. Specific anti-A...
October 12, 2017: Nutrients
https://www.readbyqxmd.com/read/29023057/dynamic-of-bacterial-diversity-in-ileum-digesta-under-water-supplements-of-antibiotics-and-probiotics
#15
Raed MahmoudAl-Atiyat
BACKGROUND AND OBJECTIVE: Intestinal bacteria plays an important role in the physiological and immunological status of birds. The present study investigated the diversity of intestinal bacterial of broilers that were fed corn-soy diet and supplements of antibiotics and probiotics. MATERIALS AND METHODS: The supplemented treatments were water, water with antibiotics, water with probiotic and water with antibiotics and probiotic. Eight randomly sampled broilers were slaughtered and their ileum digesta taken...
2017: Pakistan Journal of Biological Sciences: PJBS
https://www.readbyqxmd.com/read/29022648/probiotics-for-experimental-obesity-prevention-focus-on-strain-dependence-and-viability-of-composition
#16
Nazarii Kobyliak, Tetyana Falalyeyeva, Tetyana Beregova, Mykola Spivak
INTRODUCTION: a comparative animal study of the efficacy of intermittent short-course administration of lyophilised single-, three-, and live multistrain probiotic on obesity. METHODS: We included 70 rats divided into seven groups (n = 10 in each). Rats of group I were intact. Newborn rats of groups II-VII were injected with monosodium glutamate (MSG) (4 mg/g). Rats of group II (MSG-obesity group) were untreated. The group III-V received lyophilised monoprobiotics B...
October 12, 2017: Endokrynologia Polska
https://www.readbyqxmd.com/read/29022390/randomised-double-blind-placebo-controlled-trial-on-lactobacillus-reuteri-dsm-17938-improvement-in-symptoms-and-bowel-habit-in-functional-constipation
#17
G Riezzo, A Orlando, B D'Attoma, M Linsalata, M Martulli, F Russo
Dysbiosis may contribute to constipation and its symptoms, therefore probiotic administration could improve significantly gut health and functions. The aim of the study was to investigate the effects of a long-lasting administration of Lactobacillus reuteri DSM 17938 (LR DSM 17938) on symptoms and quality of life (QoL) score in patients with functional constipation (FC). 56 FC patients with normal colonic transit time and without anorectal disorders and pelvic floor dysfunctions completed the study. LR DSM 17938 was administered for 105 days in a randomised double-blind clinical trial (28 patients per arm)...
October 12, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/29022388/our-gut-microbiota-a-long-walk-to-homeostasis
#18
L M T Dicks, J Geldenhuys, L S Mikkelsen, E Brandsborg, H Marcotte
The microbiome of the human gastrointestinal tract (GIT) consists of billions of bacteria, fungi and viruses, of which bacteria play the most important role in nutrition, immune development, production of vitamins and maintaining a well-balanced (homeostatic) microbial population. Many papers have been published on the microbiota in the human GIT, but little is known about the first group of bacteria that colonises an infant. The intestinal tract of an unborn is, despite general belief, not sterile, but contains bacteria that have been transferred from the mother...
October 12, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/29022387/lactobacillus-plantarum-is-10506-supplementation-reduced-scorad-in-children-with-atopic-dermatitis
#19
C R S Prakoeswa, N Herwanto, R Prameswari, L Astari, S Sawitri, A N Hidayati, D M Indramaya, E R Kusumowidagdo, I S Surono
Lactobacillus plantarum IS-10506 is a novel probiotic isolated from dadih, an Indonesian traditional fermented buffalo milk. It's in vitro and in vivo probiotic properties have been assessed. Probiotic function has been shown in vivo by the suppression of allergic reactions in BALB/c mice through the action of T-regulatory cells cytokines by balancing Th1 and Th2 immune response. Atopic dermatitis (AD) is a chronic recurrent inflammatory skin disease characterised by the imbalance of Th1 and Th2. The aim of the study was to assess the probiotic function of L...
October 12, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/29022386/bacillus-toyonensis-improves-immune-response-in-the-mice-vaccinated-with-recombinant-antigen-of-bovine-herpesvirus-type-5
#20
F D S Santos, Y A Menegon, R E A Piraine, P R C Rodrigues, R C Cunha, F P Leivas Leite
Probiotics modulate the immune response and can increase the effectiveness of vaccines. Bacillus toyonensis is widely used as a probiotic in animal feed. The aim of this study was to assess the effects of B. toyonensis administration on the immune response to an experimental recombinant vaccine against bovine herpesvirus type 5 (BoHV-5) in mice. Mice were vaccinated with BoHV-5 recombinant glycoprotein D and supplemented with the probiotic B. toyonensis in two regimes: one group received the probiotic only during seven days prior to the initial vaccination while the second group was given the probiotic throughout the experimental period of seven weeks...
October 12, 2017: Beneficial Microbes
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