James Dundas, Jonathon Leipsic, Timothy Fairbairn, Nicholas Ng, Vida Sussman, Ilana Guez, Rachael Rosenblatt, Lynne M Hurwitz Koweek, Pamela S Douglas, Mark Rabbat, Gianluca Pontone, Kavitha Chinnaiyan, Bernard de Bruyne, Jeroen J Bax, Tetsuya Amano, Koen Nieman, Campbell Rogers, Hironori Kitabata, Niels P R Sand, Tomohiro Kawasaki, Sarah Mullen, Whitney Huey, Hitoshi Matsuo, Manesh R Patel, Bjarne L Norgaard, Amir Ahmadi, Georgios Tzimas
BACKGROUND: Luminal stenosis, computed tomography-derived fractional-flow reserve (FFRCT ), and high-risk plaque features on coronary computed tomography angiography are all known to be associated with adverse clinical outcomes. The interactions between these variables, patient outcomes, and quantitative plaque volumes have not been previously described. METHODS: Patients with coronary computed tomography angiography (n=4430) and one-year outcome data from the international ADVANCE (Assessing Diagnostic Value of Noninvasive FFRCT in Coronary Care) registry underwent artificial intelligence-enabled quantitative coronary plaque analysis...
March 12, 2024: Circulation. Cardiovascular Imaging