Luke Spencer, Leah Wright, Stephen J Foulkes, Stephanie J Rowe, Hayley T Dillon, Rachel Climie, Ashley Bigaran, Kristel Janssens, Amy Mitchell, Imogen Wallace, Anniina Lindqvist, Lauren Burnham, David L Prior, Erin J Howden, André La Gerche
Increased left atrial (LA) size and reduced LA function have been associated with heart failure and atrial fibrillation (AF) in at risk populations. However, atrial remodeling has also been associated with exercise training and the relationship between fitness, LA size and function has not been defined across the fitness spectrum. In a cross-sectional study of 559 ostensibly healthy participants, comprising 304 males (mean age 46 ± 20 years) and 255 females (mean age 47 ± 15 years), we sought to define the relationship between cardiorespiratory fitness (CRF), LA size and function...
March 8, 2024: American Journal of Physiology. Heart and Circulatory Physiology