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Jan Vojáček
Recently, new peroral antithrombotic agents have proved better prevention of thrombotic complications in many clinical events such as acute coronary syndrome, tromboembolic disease or atrial fibrillation. New peroral anticoagulants (NPA) were introduced - dabigatran, rivaroxaban and apixaban and new antiplatelet agents - ticagrelol and prasugrel. Outcomes of pilot studies: RE-LY, ROCKET AF, ARISTOTLE, PLATO a TIMI 38 TRITON and subsequent clinical experiences supported their usage. NPA have proved non-inferiority in incidence of stroke or systemic embolism...
April 2014: Vnitr̆ní Lékar̆ství
P Poredoš, M Jezovnik, E Kalodiki, G Andreozzi, P-L Antignani, D Clement, A Comerota, J Fareed, J Fletcher, Z Fras, M Griffin, A Markel, R Martini, A Mignano, A Nicolaides, G Novo, S Novo, K Roztočil, A Visona
Peripheral arterial disease (PAD) is one of the most frequent manifestations of atherosclerosis and is associated with atherosclerosis in the coronary and carotid arteries, leading to a highly increased incidence of cardiovascular events. Major risk factors of PAD are similar to those that lead to atherosclerosis in other vascular beds. However, there are differences in the power of individual risk factors in the different vascular territories. Cigarette smoking and diabetes mellitus represent the greatest risks of PAD...
February 2015: International Angiology: a Journal of the International Union of Angiology
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