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Radiology, Nuclear Medicine

C Boy, T Poeppel, J Kotzerke, B J Krause, H Amthauer, R P Baum, I Buchmann, S Ezziddin, D Führer, M Gabriel, T Kuwert, H Lahner, T Lauenstein, H R Maecke, J Nagarajah, F Rösch, K Scheidhauer, M Schmidt, M A Walter, A Bockisch
The present guideline is focused on quality assurance of somatostatin receptor PET/CT (SSTR-PET/CT) in oncology patients. The document has been developed by a multidisciplinary board of specialists providing consensus of definitions, prerequisites, methodology, operating procedures, assessment, and standardized reporting. In particular, imaging procedures for the two most commonly used radioligands of human SSTR, i. e. 68Ga-DOTATOC and 68Ga-DOTATATE are presented. Overall, SSTR-PET/CT requires close interdisciplinary communication and cooperation of referring and executing medical disciplines, taking into account existing guidelines and recommendations of the European and German medical societies, including the European Association of Nuclear Medicine (EANM), German Society for Endocrinology (DGE), German Society for Nuclear Medicine (DGN) and German Society for Radiology (DRG)...
February 2018: Nuklearmedizin. Nuclear Medicine
Mark Gainey, Montserrat Carles, Michael Mix, Philipp T Meyer, Michael Bock, Anca-Ligia Grosu, Dimos Baltas
Recently, there has been an increase in the imaging modalities available for radiotherapy planning and radiotherapy prognostic outcome: dual energy computed tomography (CT; DECT), dynamic contrast enhanced CT, dynamic contrast enhanced magnetic resonance imaging (MRI), diffusion-weighted MRI, positron emission tomography-CT, dynamic contrast enhanced ultrasound, magnetic resonance spectroscopy and positron emission tomography-MR. These techniques enable more precise gross tumor volume definition than CT alone and moreover allow subvolumes within the gross tumor volume to be defined which may be given a boost dose or an individual voxelized dose prescription may be derived...
March 9, 2018: Future Oncology
Francesco Ceci, Paolo Castellucci, Stefano Fanti
As precision medicine evolves, the contribution of molecular imaging to the management of prostate cancer (PCa) patients, especially for Positron Emission Tomography (PET) imaging, is gaining importance. Highly successful approaches to measure the expression of the prostate specific membrane antigen (PSMA) have been introduced recently. PSMA, the glutamate carboxypeptidase II (GCP-II), is a membrane bound metallo-peptidase that is overexpressed in 90-100% of PCa cells. Due to its selective over-expression, PSMA is a reliable tissue marker for prostate cancer and is considered an ideal target for tumor specific imaging and therapy...
March 8, 2018: Quarterly Journal of Nuclear Medicine and Molecular Imaging
Ernesto Amato, Antonio Italiano, Lucrezia Auditore, Sergio Baldari
The availability of a resource collecting dose factors for the evaluation of the absorbed doses from external exposure during the manipulation of radioactive substances is fundamental for radiological protection purposes. Monte Carlo simulations are useful for the accurate calculation of dose distributions in complex geometries, particularly in presence of extended spectra of multi-radiation sources. We considered, as possible irradiation scenarios, a point source, a uniform planar source resembling a contaminated surface, several source volumes contained in plastic or glass receptacles, and the direct skin contamination case, implementing the corresponding Monte Carlo simulations in GAMOS (GEANT4-based Architecture for Medicine-Oriented Simulations)...
February 2018: Physica Medica: PM
Ernesto Roldan-Valadez, Ulises Orbe-Arteaga, Camilo Rios
INTRODUCTION: Because we believe the journal selection before a manuscript submission deserves further investigation in each medical specialty, we aimed to evaluate the predictive ability of seven bibliometrics in the Radiology, Nuclear Medicine and Medical Imaging category of the Web of Knowledge to calculate total citations over a 7-year period. METHODS: A linear mixed effects design using random slopes and intercepts were performed on bibliometrics corresponding to 124 journals from 2007 to 2011, with their corresponding citations from 2009 to 2013, which appeared in the Journal Citations Report Science Edition...
March 5, 2018: La Radiologia Medica
Thusitha Mabotuwana, Vadiraj Hombal, Sandeep Dalal, Christopher S Hall, Martin Gunn
PURPOSE: Radiology reports often contain follow-up imaging recommendations. However, these recommendations are not always followed up by referring physicians and patients. Failure to comply in a timely manner can lead to delayed treatment, poor patient outcomes, unnecessary testing, lost revenue, and legal liability. Therefore, the primary objective of this research was to determine adherence rates to follow-up recommendations. METHODS: We extracted radiology examination-related data, including report text, for examinations performed between January 1, 2010, and February 28, 2017, from the radiology information system at an academic institution...
March 2018: Journal of the American College of Radiology: JACR
Milton J Guiberteau, M Elizabeth Oates
No abstract text is available yet for this article.
March 2018: Journal of the American College of Radiology: JACR
Fabian Kiessling
ᅟ: KEY POINTS: • Radiomics and radiogenomics will merge radiology, nuclear medicine, pathology and laboratory medicine. • Automation of image data analysis will change the daily routine work. • Image-guided therapy and handling complex radiogenomic data will play a major role.
February 27, 2018: European Radiology
Ivo Trogrlić, Dragan Trogrlić, Darko Trogrlić, Amina Kadrić Trogrlić
BACKGROUND: In the latest years, a lot of research studies regarding the usage of active agents from plants in the treatment of tumors have been published, but there is no data about successful usage of herbal remedies in the treatment of glioblastoma in humans. METHODS: The phytotherapy involved five types of herbal medicine which the subjects took in the form of tea, each type once a day at regular intervals. Three patients took herbal medicine along with standard oncological treatment, while two patients applied for phytotherapy after completing medical treatment...
February 13, 2018: World Journal of Surgical Oncology
John J Kellett, Gregory A Lovell, David A Eriksen, Matthew J Sampson
Literature on the various techniques for imaging injuries to the ankle syndesmosis to determine the most appropriate imaging modality for diagnosing syndesmosis ligament disruption and instability was reviewed using the following data sources: Pubmed, Google scholar, SportsDiscus, E-journals and PLOSone. Search terms used were: syndesmosis paired with injury, imaging, radiology, X-ray, stress X-ray, arthrography, ultrasound, nuclear medicine scan, CT scan, MRI and arthroscopy. Articles were selected by reading abstracts and the full article if indicated...
February 5, 2018: Journal of Medical Imaging and Radiation Oncology
Kenneth Alan Miles, Julia Squires, Michelle Murphy
RATIONALE AND OBJECTIVE: This study aims to identify potential barriers to the clinical implementation of quantitative imaging for the assessment of tumor heterogeneity. MATERIALS AND METHODS: An 18-month prospective observational study was undertaken in which the clinical implementation of computed tomography texture analysis (CTTA) as a technique for quantifying tumor heterogeneity in patients with non-small cell lung cancer was assessed using the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework...
February 2, 2018: Academic Radiology
H Al-Chalabi, A Cook, C Ellis, C N Patel, A F Scarsbrook
AIM: To assess the feasibility and efficacy of a streamlined single time-point 99mTc-HYNIC-Tyr3-octreotide (Tektrotyd) somatostatin receptor scintigraphy (SRS) protocol to differentiate pathological uptake by neuroendocrine tumours (NETs) from physiological activity. METHODS AND MATERIALS: Tektrotyd imaging in 50 consecutive patients with NETs was reviewed retrospectively. Imaging was independently assessed by two experienced reporters with dual-certification in radiology and nuclear medicine and agreed in consensus...
February 1, 2018: Clinical Radiology
Hian L Huang, Warren Fong, Wee M Peh, Kasat A Niraj, Winnie W Lam
Purpose: Our case series aims to study the growing use of FDG PET/CT in diagnostic evaluation and follow up of IgG4-RD with emphasis on patients presenting with coronary artery involvement. Methods: We conducted a search on the nuclear medicine and rheumatology service databases and identified patients with histologically proven IgG4-RD with FDG PET/CT performed at the Singapore General Hospital. The radiological, clinical, and laboratory findings of these patients were analyzed retrospectively...
February 2018: Nuclear Medicine and Molecular Imaging
Alberto Signore, Kelly Luz Anzola, Sveva Auletta, Michela Varani, Agnese Petitti, Marta Pacilio, Filippo Galli, Chiara Lauri
In the field of inflammation imaging, nuclear medicine techniques can be considered as a non-invasive tool to early detect pathophysiological changes I affected tissues. These changes usually occur before clinical onset of symptoms and before the development of anatomical changes, that are commonly detected by radiological procedures. This is particularly important for prognostic purposes, therapy decision making and for therapy follow-up. Here we review the current state-of-theart of nuclear medicine for diagnostic purposes in different conditions characterized by a chronic inflammation, such as vulnerable atherosclerotic plaques, vasculitides, rheumatoid arthritis, Sjogren syndrome, autoimmune thyroid diseases, inflammatory bowel diseases, Coeliac disease, Type 1 diabetes mellitus and other immunological diseases...
January 29, 2018: Current Pharmaceutical Design
Bari Dane, Ankur Doshi, Soterios Gfytopoulos, Priya Bhattacharji, Michael Recht, William Moore
OBJECTIVES AND RATIONALE: Radiology-pathology correlation is time-consuming and is not feasible in most clinical settings, with the notable exception of breast imaging. The purpose of this study was to determine if an automated radiology-pathology report pairing system could accurately match radiology and pathology reports, thus creating a feedback loop allowing for more frequent and timely radiology-pathology correlation. METHODS: An experienced radiologist created a matching matrix of radiology and pathology reports...
January 17, 2018: Academic Radiology
Kamil Szewczak, Iwona Słonecka, Katarzyna Wołoszczuk, Zuzanna Podgórska, Łukasz Modzelewski
The paper presents the capabilities of CLOR's facility for calibrating radiological protection instruments and the important conclusions drawn from the results of calibrating instruments used in Nuclear Medicine Departments in Poland. The analysis was based on results of the certified calibration of chosen instruments. The result for five types of instruments dedicated for dose rate and contamination measurements were presented. They prove the importance of the calibration process. They show that the calibration factor for one particular instrument may fluctuate by 50% in a one year period as well as by more than 100% for two instruments of the same type...
January 10, 2018: Nuclear Medicine Review. Central & Eastern Europe
D Bazyka
After the creation of the Academy of Medical Sciences of Ukraine in 1993 the Research Center for Radiation Medicine was among the first institutions to join the Academy (fig. 1). Estab lishing the Academy was among the first steps of the independent Ukrainian government and aimed to provide a high level health care for population. It was extremely needed for the minimization of Chornobyl medical consequences. This choice was related to a growing recognition of the scientific research in fulfilling the Сenter's mission - study of the effects of low dose radiation on human body and radiation protection of the exposed population...
December 2017: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
Craig Williamson, Larry Morgan, Joshua P Klein
The use of neuroimaging in conjunction with serial neurological examinations is a core component of modern neurocritical care practice. Although there is a growing role for other neuromonitoring techniques, the ability to quickly and accurately interpret images in the context of a patient's clinical status arguably remains the indispensable skill for neurocritical care practitioners. Due to its rapid acquisition time and excellent ability to detect intracerebral hemorrhage (ICH), cerebral edema, and signs of elevated intracranial pressure, computed tomography (CT) remains the most useful neuroimaging technique for intensive care unit (ICU) patients...
December 2017: Seminars in Respiratory and Critical Care Medicine
Anand Narayan, Katie Lobner, Jan Fritz
OBJECTIVE: The open access movement has pushed for greater access to scientific knowledge by expanding access to scientific journal articles. There is limited information about the extent to which open access policies have been adopted by radiology journals. We performed a systematic analysis to ascertain the proportion of radiology journals with open access options. MATERIALS AND METHODS: A search was performed with the assistance of a clinical informationist. Full and mixed English-language diagnostic and interventional radiology Web of Science journals (impact factors > 1...
December 11, 2017: Journal of the American College of Radiology: JACR
M A Hentschel, H P M Kunst, M M Rovers, S C A Steens
OBJECTIVE: To evaluate diagnostic accuracy of high-resolution T2-weighted MRI (T2w) for detecting cerebellopontine angle (CPA) lesions compared to a combined protocol including gadolinium enhanced T1-weighted MRI (GdT1w). SETTING: Department of Radiology & Nuclear Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands. PARTICIPANTS: A random sample of MRIs from 350 patients (700 CPAs) with asymmetrical audiovestibular complaints was used, acquired between 2013 and 2016...
December 14, 2017: Clinical Otolaryngology
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