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https://www.readbyqxmd.com/read/29303129/higher-order-multiple-births-in-nigeria-experiences-challenges-and-neonatal-outcomes-in-a-private-health-facility
#1
B Ezenwa, O Oseni, P Akintan, P Aligwekwe, B Chukwukelu, O Fashola, A Ogunmokun, O Odukoya
OBJECTIVES: The aim of this study is to describe the experience and outcome of higher order multiple (HOM) births in a private tertiary health facility in Nigeria. MATERIALS AND METHODS: This was a retrospective review of records of HOM over 3 years in a private tertiary health facility in Nigeria. Relevant data on HOM births were extracted from both the patients' case notes, admission registers and maternity ward and delivery records of the hospital using a predesigned pro forma...
November 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29291466/3d-3d-facial-superimposition-between-monozygotic-twins-a-novel-morphological-approach-to-the-assessment-of-differences-due-to-environmental-factors
#2
Daniele Gibelli, Valentina Pucciarelli, Pasquale Poppa, Danilo De Angelis, Marco Cummaudo, Luca Pisoni, Marina Codari, Cristina Cattaneo, Chiarella Sforza
Distinction of one twin with respect to the other, based on external appearance, is challenging; nevertheless, facial morphology may provide individualizing features that may help distinguish twin siblings. This study aims at exposing an innovative method for the facial assessment in monozygotic twins for personal identification, based on the registration and comparison of 3D models of faces. Ten couples of monozygotic twins aged between 25 and 69 years were acquired twice by a stereophotogrammetric system (VECTRA-3D® M3: Canfield Scientific, Inc...
December 27, 2017: Legal Medicine
https://www.readbyqxmd.com/read/29282159/twins-as-participants-in-randomized-controlled-trials-a-review-of-published-literature
#3
Athula Sumathipala, Lisa Yelland, Debra Green, Tom Shepherd, Kaushalya Jayaweera, Paulo Ferreira, Jeffrey M Craig
Monozygotic (MZ) and dizygotic (DZ) twins participate in research that partitions variance in health, disease, and behavior into genetic and environmental components. However, there are other innovative roles for twins in medical research. One such way is involving MZ and/or DZ twins in co-twin control-designed randomized controlled trials (RCTs). To our knowledge, no reviews have been conducted that summarizes the involvement of twins in RCTs. Therefore, we conducted a systematic literature search using the U...
December 28, 2017: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/29275276/fragile-x-associated-premature-ovarian-failure-in-a-large-turkish-cohort-findings-of-hacettepe-fragile-x-registry
#4
Gülen Eda Utine, Pelin Özlem Şimşek-Kiper, Özlem Akgün-Doğan, Gizem Ürel-Demir, Yasemin Alanay, Dilek Aktaş, Koray Boduroğlu, Ergül Tunçbilek, Mehmet Alikaşifoğlu
OBJECTIVE: To determine frequency of fragile X associated premature ovarian insufficiency (FXPOI) among Turkish premutation carriers. STUDY DESIGN: FMR1 premutation is the single most common genetic cause of POI (FXPOI). Fragile X Registry at Hacettepe University has been reviewed for the frequency of FXPOI among female premutation carriers. Since 1991 when FMR1 testing was available, 760 individuals from 243 families have been registered. Actual data on menstrual status of female premutation carriers were gathered and analysed...
December 16, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29258629/aspects-of-the-history-of-twin-research-statistical-congresses-in-the-19th-century-and-hellin-s-law
#5
Johan Fellman
In the 19th century, a series of international statistical congresses began that were important for population studies, including twin research. The introduction of common rules for the national demographic registers enabled scientists to contribute to the genesis of statistical research. The congress in St. Petersburg in 1872, in particular, focused on the movements of the population, and how they should be registered. Among the facts to be recorded were in multiple births, the sex and number of children born alive or still-born, whether legitimate or illegitimate, and the age of the mother at the date of the births...
December 20, 2017: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/29246205/the-autism-tics-adhd-and-other-comorbidities-inventory-a-tac-previous-and-predictive-validity
#6
Caroline Mårland, Paul Lichtenstein, Alessio Degl'Innocenti, Tomas Larson, Maria Råstam, Henrik Anckarsäter, Christopher Gillberg, Thomas Nilsson, Sebastian Lundström
BACKGROUND: Reliable and easy to administer screening instruments focusing on neurodevelopmental disorders and associated conditions are scarce. The Autism-Tics, AD/HD and other Comorbidities inventory (A-TAC) has previously been validated and reporting good- excellent validity for several disorders. This article aims to expand these findings by including more conditions in a substantially larger sample augmented with the Swedish National Patient Register (NPR). METHODS: Since 2004 parents of all 9-year-old Swedish twins have been invited to participate in a telephone interview in the Child and Adolescent Twin Study in Sweden, CATSS...
December 16, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29240646/genetic-and-environmental-contributions-to-sleep-quality-and-low-back-pain-a-population-based-twin-study
#7
Marina B Pinheiro, Jose J Morosoli, Manuela L Ferreira, Juan J Madrid-Valero, Kathryn Refshauge, Paulo H Ferreira, Juan R Ordoñana
OBJECTIVE: To estimate the extent to which the co-occurrence of poor sleep quality and low back pain is due to the same genetic and/or environmental risk factors or due to a causal association. METHODS: Cross-sectional data on sleep quality (Pittsburgh Sleep Quality index) and low back pain were collected in a population-based sample of adult twins (n=2,134) registered with the Murcia Twin Registry. Bivariate analysis and structural equation modelling were used...
December 13, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/29238796/sources-of-parent-offspring-resemblance-for-major-depression-in-a-national-swedish-extended-adoption-study
#8
Kenneth S Kendler, Henrik Ohlsson, Kristina Sundquist, Jan Sundquist
Importance: Twin studies have assessed sibling resemblance for major depression (MD) but cannot address sources of resemblance across generations. Objective: To clarify the relative importance of genetic and rearing effects on the parent-offspring resemblance for MD. Design: This Swedish population register-based study examined parents and children from the following 5 family types: intact (2 041 816 offspring), adoptive (14 104 offspring), not-lived-with (NLW) father (116 601 offspring), stepfather (67 826 offspring), and triparental (29 205 offspring)...
December 13, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/29228387/association-between-rs1051730-and-smoking-during-pregnancy-in-dutch-women
#9
Hamdi Mbarek, Catharina E M van Beijsterveldt, Jouke Jan Hottenga, Conor V Dolan, Dorret I Boomsma, Gonneke Willemsen, Jacqueline M Vink
Introduction: The common genetic variant (rs1051730) in the 15q24 nicotinic acetylcholine receptor gene cluster CHRNA5-CHRNA3-CHRNB4 was associated with smoking quantity and has been reported to be associated also with reduced ability to quit smoking in pregnant women but results were inconsistent in non pregnant women. The aim of this study was to explore the association between rs1051730 and smoking cessation during pregnancy in a sample of Dutch women. Methods: Data on smoking during pregnancy were available from 1,337 women who ever smoked registered at the Netherlands Twin Register (NTR)...
December 8, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29220643/polygenic-risk-for-alcohol-consumption-and-its-association-with-alcohol-related-phenotypes-do-stress-and-life-satisfaction-moderate-these-relationships
#10
Gabry W Mies, Karin J H Verweij, Jorien L Treur, Lannie Ligthart, Iryna O Fedko, Jouke Jan Hottenga, Gonneke Willemsen, Meike Bartels, Dorret I Boomsma, Jacqueline M Vink
BACKGROUND: Genetic and environmental factors contribute about equally to alcohol-related phenotypes in adulthood. In the present study, we examined whether more stress at home or low satisfaction with life might be associated with heavier drinking or more alcohol-related problems in individuals with a high genetic susceptibility to alcohol use. METHODS: Information on polygenic scores and drinking behavior was available in 6705 adults (65% female; 18-83 years) registered with the Netherlands Twin Register...
December 2, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29195773/cognitive-deficits-in-bipolar-disorders-implications-for-emotion
#11
REVIEW
Isabela M M Lima, Andrew D Peckham, Sheri L Johnson
Prominent cognitive deficits have been documented in bipolar disorder, and multiple studies suggest that these deficits can be observed among non-affected first-degree relatives of those with bipolar disorder. Although there is variability in the degree of cognitive deficits, these deficits are robustly relevant for functional outcomes. A separate literature documents clear difficulties in emotionality, emotion regulation, and emotion-relevant impulsivity within bipolar disorder, and demonstrates that these emotion-relevant variables are also central to outcome...
November 21, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/29177076/effectiveness-and-efficiency-of-different-weight-machine-based-strength-training-programmes-for-patients-with-hip-or-knee-osteoarthritis-a-protocol-for-a-quasi-experimental-controlled-study-in-the-context-of-health-services-research
#12
Inga Krauss, Gerhard Müller, Benjamin Steinhilber, Georg Haupt, Pia Janssen, Peter Martus
Introduction: Osteoarthritis is a chronic musculoskeletal disease with a major impact on the individual and the healthcare system. As there is no cure, therapy aims for symptom release and reduction of disease progression. Physical exercises have been defined as a core treatment for osteoarthritis. However, research questions related to dose response, sustainability of effects, economic efficiency and safety are still open and will be evaluated in this trial, investigating a progressive weight machine-based strength training...
2017: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29174128/intrauterine-insemination-with-ovarian-stimulation-versus-expectant-management-for-unexplained-infertility-tui-a-pragmatic-open-label-randomised-controlled-two-centre-trial
#13
Cynthia M Farquhar, Emily Liu, Sarah Armstrong, Nicola Arroll, Sarah Lensen, Julie Brown
BACKGROUND: Women with unexplained infertility are often offered intrauterine insemination (IUI) with ovarian stimulation as an alternative to in-vitro fertilisation (IVF). However, little evidence exists that IUI is an effective treatment. In 2013, the UK National Institute for Health and Care Excellence recommended that IUI should not be routinely offered for couples with unexplained infertility. METHODS: For this pragmatic, open-label, randomised, controlled, two-centre study, we enrolled women attending two fertility clinics in New Zealand with unexplained infertility and an unfavourable prognosis of natural conception...
November 23, 2017: Lancet
https://www.readbyqxmd.com/read/29168022/no-advantage-of-fresh-blastocyst-versus-cleavage-stage-embryo-transfer-in-women-under-the-age-of-39-a-randomized-controlled-study
#14
Paolo Emanuele Levi-Setti, Federico Cirillo, Antonella Smeraldi, Emanuela Morenghi, Giulia E G Mulazzani, Elena Albani
PURPOSE: Is there a difference in implantation and pregnancy rates between embryos transferred electively at cleavage or blastocyst stage in infertile women ≤ 38 years with at least four zygotes on day 1 post retrieval? METHODS: A randomized clinical trial was conducted in a single tertiary care hospital with a sample size of 194 patients in each arm for a total population of 388 women. Patients less than 39 years of age with more than three fertilized oocytes and less than four previous assisted reproductive technology (ART) attempts were inclusion criteria...
November 22, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29150678/dog-ownership-and-the-risk-of-cardiovascular-disease-and-death-a-nationwide-cohort-study
#15
Mwenya Mubanga, Liisa Byberg, Christoph Nowak, Agneta Egenvall, Patrik K Magnusson, Erik Ingelsson, Tove Fall
Dogs may be beneficial in reducing cardiovascular risk in their owners by providing social support and motivation for physical activity. We aimed to investigate the association of dog ownership with incident cardiovascular disease (CVD) and death in a register-based prospective nation-wide cohort (n = 3,432,153) with up to 12 years of follow-up. Self-reported health and lifestyle habits were available for 34,202 participants in the Swedish Twin Register. Time-to-event analyses with time-updated covariates were used to calculate hazard ratios (HR) with 95% confidence intervals (CI)...
November 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29138598/familial-aggregation-of-myasthenia-gravis-in-affected-families-a-population-based-study
#16
Fu-Chao Liu, Chang-Fu Kuo, Lai-Chu See, Hsin-I Tsai, Huang-Ping Yu
Introduction: Myasthenia gravis (MG) is clinically heterogeneous and can be life-threatening if bulbar or respiratory muscles are involved. However, relative contributions of genetic, shared, and nonshared environmental factors to MG susceptibility remain unclear. The aim of this study was to examine the familial aggregation and heritability of MG and the relative risks (RRs) of other autoimmune diseases in the relatives of patients with MG. Methods: A population-based family study using the Taiwan National Health Insurance (NHI) Database was conducted...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/29125095/social-comparison-orientation-in-monozygotic-and-dizygotic-twins
#17
Pascal Huguet, Michèle Carlier, Conor V Dolan, Eco J de Geus, Dorret I Boomsma
Twin research has offered evidence that monozygotic (MZ) twins are more socially close than dizygotic (DZ) twins, but has not paid much attention to the way twins compare themselves with their co-twin. The few studies in this area suggest that 'horizontal comparisons' (social comparison motivated by solidarity or communion with others) matter more for MZ twins than for DZ twins, at least when the co-twin is the social comparison standard. Consistent with this view, we predicted higher interest in MZ twins relative to DZ twins to select their co-twin rather than other people in general as the social comparison standard...
November 10, 2017: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/29119001/a-swedish-national-adoption-study-of-risk-of-irritable-bowel-syndrome-ibs
#18
Rasmus Waehrens, Bengt Zöller, Jan Sundquist, Kristina Sundquist, MirNabi Pirouzifard
Objectives: Irritable bowel syndrome (IBS) clusters in families, but the familial risk of IBS has not been determined in adoptees. Studying adoptees and their biological and adoptive parents is a strong study design for separating genetic from environmental causes of familial clustering. This nationwide study aimed to separate the biological (genetic) and familial environmental contribution to the familial transmission of IBS. Methods: We performed a family study for Swedish-born adoptees born from 1951 until 1995, and their biological and adoptive parents...
2017: BMJ Open Gastroenterology
https://www.readbyqxmd.com/read/29117383/assisted-reproductive-technology-in-europe-2013-results-generated-from-european-registers-by-eshre
#19
C Calhaz-Jorge, C De Geyter, M S Kupka, J de Mouzon, K Erb, E Mocanu, T Motrenko, G Scaravelli, C Wyns, V Goossens
STUDY QUESTION: Are there any changes in the treatments involving ART and IUI initiated in Europe during 2013 compared with previous years? SUMMARY ANSWER: An increase in the overall number of ART cycles resulting from a higher number of countries reporting data was evident, the pregnancy rates (PRs) in 2013 remained stable compared with those reported in 2012, the number of transfers with multiple embryos (3+) was lower than ever before yet the multiple delivery rates (DRs) remained unchanged, and IUI activity and success rates were similar to those of last years...
October 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29108135/regimens-of-ultrasound-surveillance-for-twin-pregnancies-for-improving-outcomes
#20
REVIEW
Jane G Woolcock, Rosalie M Grivell, Jodie M Dodd
BACKGROUND: Increased ultrasound surveillance of twin pregnancies has become accepted practice due to the higher risk of complications. There is no current consensus however as to the method and frequency of ultrasound monitoring that constitutes optimal care. OBJECTIVES: To systematically review the effects of different types and frequency of ultrasound surveillance for women with a twin pregnancy on neonatal, fetal and maternal outcomes. SEARCH METHODS: We searched Cochrane Pregnancy and Childbirth's Trials Register, ClinicalTrials...
November 7, 2017: Cochrane Database of Systematic Reviews
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