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Danish register

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https://www.readbyqxmd.com/read/29235044/worse-survival-after-breast-cancer-in-women-with-anorexia-nervosa
#1
Annet Bens, Fotios C Papadopoulos, Eero Pukkala, Anders Ekbom, Mika Gissler, Lene Mellemkjær
PURPOSE: A history of anorexia nervosa has been associated with a reduced risk of developing breast cancer. We investigated survival after breast cancer among women with a prior anorexia nervosa diagnosis compared with women in a population comparison group. METHODS: This register-based study included combined data from Sweden, Denmark and Finland. A total of 76 and 1462 breast cancer cases identified among 22,654 women with anorexia nervosa and 224,619 women in a population comparison group, respectively, were included in the study...
December 12, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29229680/prenatal-paternal-selective-serotonin-reuptake-inhibitors-use-and-risk-of-adhd-in-offspring
#2
Fen Yang, Hong Liang, Jianping Chen, Maohua Miao, Wei Yuan, Mette Nørgaard, Jiong Li
OBJECTIVES: It has been shown that maternal prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) may be a risk factor for attention-deficit/hyperactivity disorder (ADHD) in offspring. Our goal was to examine whether paternal SSRI use before conception increases the risk of ADHD in offspring. METHODS: On the basis of Danish national registers, we conducted a cohort study of 781 470 singletons born between 1996 and 2008 with follow-up throughout 2013...
December 11, 2017: Pediatrics
https://www.readbyqxmd.com/read/29217620/risk-of-second-malignant-neoplasm-and-mortality-in-patients-with-rheumatoid-arthritis-treated-with-biological-dmards-a-danish-population-based-cohort-study
#3
Lene Dreyer, René L Cordtz, Inger Marie J Hansen, Lars Erik Kristensen, Merete L Hetland, Lene Mellemkjaer
OBJECTIVE: To study the risk of a second malignant neoplasm (SMN) and mortality in patients with rheumatoid arthritis (RA) with a history of a primary cancer diagnosis and treated with biological disease-modifying antirheumatic drugs (bDMARD). METHODS: Among patients with RA (n=15 286) registered in the DANBIO Register during 2000-2011, 1678 had a primary cancer according to the Danish Cancer Registry. HRs for SMN and death were calculated. RESULTS: During follow-up there were 279 patients with RA contributing person-years to the bDMARDs use before their primary cancer diagnosis, 220 to the only after, 92 to the both before and after, while 1203 patients with RA contributed to the non-use strata...
December 7, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29217395/out-of-hospital-cardiac-arrest-probability-of-bystander-defibrillation-relative-to-distance-to-nearest-automated-external-defibrillator
#4
Kathrine B Sondergaard, Steen Moller Hansen, Jannik L Pallisgaard, Thomas Alexander Gerds, Mads Wissenberg, Lena Karlsson, Freddy K Lippert, Gunnar H Gislason, Christian Torp-Pedersen, Fredrik Folke
AIMS: Despite wide dissemination of automated external defibrillators (AEDs), bystander defibrillation rates remain low. We aimed to investigate how route distance to the nearest accessible AED was associated with probability of bystander defibrillation in public and residential locations. METHODS: We used data from the nationwide Danish Cardiac Arrest Registry and the Danish AED Network to identify out-of-hospital cardiac arrests and route distances to nearest accessible registered AED during 2008-2013...
December 4, 2017: Resuscitation
https://www.readbyqxmd.com/read/29211785/the-role-of-the-clinical-departments-for-understanding-patient-heterogeneity-in-one-year-mortality-after-a-diagnosis-of-heart-failure-a-multilevel-analysis-of-individual-heterogeneity-for-profiling-provider-outcomes
#5
Nermin Ghith, Anne Frølich, Juan Merlo
PURPOSE: To evaluate the general contextual effect (GCE) of the hospital department on one-year mortality in Swedish and Danish patients with heart failure (HF) by applying a multilevel analysis of individual heterogeneity. METHODS: Using the Swedish patient register, we obtained data on 36,943 patients who were 45-80 years old and admitted for HF to the hospital between 2007 and 2009. From the Danish Heart Failure Database (DHFD), we obtained data on 12,001 patients with incident HF who were 18 years or older and treated at hospitals between June 2010 and June2013...
2017: PloS One
https://www.readbyqxmd.com/read/29207930/the-rise-and-fall-of-an-opt-out-system
#6
Francisca Nordfalk, Klaus Hoeyer
INTRODUCTION: In Denmark, citizens participate in register-based research without the possibility of opting out. However, in 1995 it was made possible for Danish citizens to register an opt-out called 'researcher protection' [ forskerbeskyttelse], which implied that researchers could not contact people to invite them to participate in research projects, such as clinical trials or questionnaries, based on their registrations in national registers. Data already registered could still be used for research...
December 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/29205446/induced-smoothing-for-rank-based-regression-with-recurrent-gap-time-data
#7
Tianmeng Lyu, Xianghua Luo, Gongjun Xu, Chiung-Yu Huang
Various semiparametric regression models have recently been proposed for the analysis of gap times between consecutive recurrent events. Among them, the semiparametric accelerated failure time (AFT) model is especially appealing owing to its direct interpretation of covariate effects on the gap times. In general, estimation of the semiparametric AFT model is challenging because the rank-based estimating function is a nonsmooth step function. As a result, solutions to the estimating equations do not necessarily exist...
December 4, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/29203131/electroconvulsive-therapy-and-subsequent-epilepsy-in-patients-with-affective-disorders-a-register-based-danish-cohort-study
#8
Fie Krossdal Bøg, Martin Balslev Jørgensen, Zorana Jovanovic Andersen, Merete Osler
OBJECTIVE: It has been suggested that Electroconvulsive Therapy (ECT) might increase the risk of epilepsy but the few patient studies with retrospective data from medical records do not support the hypothesis. The aim of this study was to examine the relationship between ECT and subsequent incident epilepsy in patients with affective disorder. We also explored whether any association varied with number of ECTs and time since last treatment. METHODS: All 169,457 patients with first hospital contact for an affective disorder between January 2005 and December 2015 were identified in the Danish National Patient Registry and followed for incident epilepsy from January 2005 until November 2016...
November 26, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/29202806/risk-factors-for-joint-replacement-in-knee-osteoarthritis-a-15-year-follow-up-study
#9
Flemming K Nielsen, Niels Egund, Anette Jørgensen, Anne Grethe Jurik
BACKGROUND: To evaluate whether clinical, radiographic or MRI findings are associated with long term risk for total knee arthroplasty (TKA) in persons with knee osteoarthritis. METHODS: We performed a follow-up analysis of 100 persons with knee osteoarthritis who participated in a clinical trial between 2000 and 2002. Clinical data as well as radiography and MRI of the inclusion knee were obtained in all participants. Data on TKA procedures were extracted from The Danish National Patient Register...
December 4, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29202615/the-accuracy-of-preoperative-staging-of-the-axilla-in-primary-breast-cancer-a-national-register-based-study-on-behalf-of-danish-breast-cancer-group-dbcg
#10
Kristine Hamran, Linnea Langhans, Ilse Vejborg, Tove Filtenborg Tvedskov, Niels Kroman
No abstract text is available yet for this article.
December 5, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/29198736/venous-thromboembolic-complications-to-hysterectomy-for-benign-disease-a-nationwide-cohort-study
#11
Henriette Strøm Kahr, Ole Thorlacius-Ussing, Ole Bjarne Christiansen, Regitze Kuhr Skals, Christian Torp-Pedersen, Aage Knudsen
STUDY OBJECTIVE: To estimate the risk of venous thromboembolic complications following abdominal, laparoscopic and vaginal hysterectomy when performed for benign disorders. DESIGN: Nationwide cohort study (Canadian Task Force Classification II-2). SETTING: Data from Danish national registers on all women undergoing hysterectomy for benign conditions in the period 1996-2015. PATIENTS: Women aged 18 and above who underwent hysterectomy for benign disease were stratified into 3 groups according to hysterectomy approach: abdominal, laparoscopic or vaginal...
November 30, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29198022/hyperthyroid-patients-without-graves-orbitopathy-are-not-at-increased-risk-of-developing-glaucoma-a-nationwide-danish-register-based-case-control-study
#12
F Brandt, M Thvilum, L Hegedüs, T H Brix
PURPOSE: Graves' disease (GD) and toxic nodular goiter (TNG) are associated with various comorbidities. However, it is unclarified whether TNG and GD without orbitopathy are associated with glaucoma. METHODS: This was a case-control study using record-linkage data from nationwide Danish health registers. 28,461 patients with GD and 17,283 with TNG were included. Each case was age and sex matched with four non-hyperthyroid controls and followed over a mean period of 8 years...
December 2, 2017: Endocrine
https://www.readbyqxmd.com/read/29197414/integrated-mental-health-care-and-vocational-rehabilitation-to-improve-return-to-work-rates-for-people-on-sick-leave-because-of-depression-and-anxiety-the-danish-ibbis-trial-study-protocol-for-a-randomized-controlled-trial
#13
Rie Poulsen, Andreas Hoff, Jonas Fisker, Carsten Hjorthøj, Lene Falgaard Eplov
BACKGROUND: Depression and anxiety are among the largest contributors to the global burden of disease and have negative effects on both the individual and society. Depression and anxiety are very likely to influence the individual's work ability, and up to 40% of the people on sick leave in Denmark have depression and/or anxiety. There is no clear evidence that treatment alone will provide sufficient support for vocational recovery in this group. Integrated vocational and health care services have shown good effects on return to work in other, similar welfare contexts...
December 2, 2017: Trials
https://www.readbyqxmd.com/read/29197404/integrated-mental-health-care-and-vocational-rehabilitation-to-improve-return-to-work-rates-for-people-on-sick-leave-because-of-exhaustion-disorder-adjustment-disorder-and-distress-the-danish-ibbis-trial-study-protocol-for-a-randomized-controlled-trial
#14
Rie Poulsen, Jonas Fisker, Andreas Hoff, Carsten Hjorthøj, Lene Falgaard Eplov
BACKGROUND: Common mental disorders are important contributors to the global burden of disease and cause negative effects on both the individual and society. Stress-related disorders influence the individual's workability and cause early retirement pensions in Denmark. There is no clear evidence that mental health care alone will provide sufficient support for vocational recovery for this group. Integrated vocational and health care services have shown good effects on return to work in other similar welfare contexts...
December 2, 2017: Trials
https://www.readbyqxmd.com/read/29194280/conization-and-healthcare-use-a-population-based-register-study
#15
Maria E Frederiksen, Miguel Vázquez-Prada Baillet, Pernille T Jensen, Carsten Rygaard, Jesper Hallas, Elsebeth Lynge
The aim of this study was to assess whether negative psychological consequences of conization reported in questionnaire studies translated into increased use of the healthcare services that could relieve such symptoms. This was a population-based register study comparing women undergoing conization with a control group of women with normal cytology results. Data were derived from Danish registers. Using the difference-in-differences method, we measured contacts with general practitioners (GPs), hospitals, psychiatrist/psychologists, and use of anxiolytic and antidepressant prescription drugs over 5 years 'before' and 'after' the conization in the study group, and in comparable periods in the control group...
November 29, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/29179576/rates-and-predictors-of-conversion-to-schizophrenia-or-bipolar-disorder-following-substance-induced-psychosis
#16
Marie Stefanie Kejser Starzer, Merete Nordentoft, Carsten Hjorthøj
OBJECTIVE: The authors investigated the rates of conversion to schizophrenia and bipolar disorder after a substance-induced psychosis, as well as risk factors for conversion. METHOD: All patient information was extracted from the Danish Civil Registration System and the Psychiatric Central Research Register. The study population included all persons who received a diagnosis of substance-induced psychosis between 1994 and 2014 (N=6,788); patients were followed until first occurrence of schizophrenia or bipolar disorder or until death, emigration, or August 2014...
November 28, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29173965/complications-and-patient-injury-after-ankle-fracture-surgery-a-closed-claim-analysis-with-data-from-the-patient-compensation-association-in-denmark
#17
Naja Bjørslev, Lars Bo Ebskov, Camilla Mersø, Christian Wong
BACKGROUND: The Patient Compensation Association (PCA) receives claims for financial compensation from patients who believe they have sustained damage from their treatment in the Danish health care system. In this study, we have analysed closed claims in which patients suffered injuries due to the surgical treatment of their ankle fracture. We identified causalities contributing to these injuries and malpractices, as well as the economic consequences of these damages. METHODS: Fifty-one approved closed claims from the PCA database from the years 2004-2009 were analysed in a retrospective systematic review...
November 21, 2017: Injury
https://www.readbyqxmd.com/read/29173212/substitutions-between-dairy-product-subgroups-and-risk-of-type-2-diabetes-the-danish-diet-cancer-and-health-cohort
#18
Daniel B Ibsen, Anne Sofie D Laursen, Lotte Lauritzen, Anne Tjønneland, Kim Overvad, Marianne U Jakobsen
The aim of this study was to investigate the associations for specified substitutions between different subgroups of dairy products and the risk of type 2 diabetes. We used data from the Danish Diet, Cancer and Health cohort including 54 277 men and women aged 50-64 years at baseline. Information regarding intake of dairy products was obtained from a validated FFQ, and cases of type 2 diabetes were identified through the Danish National Diabetes Register. Cox proportional hazards regressions were used to estimate associations...
November 27, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/29172228/adverse-life-events-increase-risk-for-postpartum-psychiatric-episodes-a-population-based-epidemiologic-study
#19
S Meltzer-Brody, J T Larsen, L Petersen, J Guintivano, A Di Florio, W C Miller, P F Sullivan, T Munk-Olsen
BACKGROUND: Trauma histories may increase risk of perinatal psychiatric episodes. We designed an epidemiological population-based cohort study to explore if adverse childhood experiences (ACE) in girls increases risk of later postpartum psychiatric episodes. METHODS: Using Danish registers, we identified women born in Denmark between January 1980 and December 1998 (129,439 childbirths). Exposure variables were ACE between ages 0 and 15 including: (1) family disruption, (2) parental somatic illness, (3) parental labor market exclusion, (4) parental criminality, (5) parental death, (6) placement in out-of-home care, (7) parental psychopathology excluding substance use, and (8) parental substance use disorder...
November 24, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/29168674/breast-conserving-surgery-versus-mastectomy-overall-and-relative-survival-a-population-based-study-by-the-danish-breast-cancer-cooperative-group-dbcg
#20
Peer Christiansen, Stina Lyck Carstensen, Bent Ejlertsen, Niels Kroman, Birgitte Offersen, Anne Bodilsen, Maj-Britt Jensen
BACKGROUND: Observational studies have pointed at a better survival after breast conserving surgery (BCS) compared with mastectomy. The aim of the present study was to evaluate whether this remains true when more extensive tumor characteristics and treatment data were included. METHODS: The cohort included patients registered after primary surgery for early invasive breast cancer in the database of the Danish Breast Cancer Cooperative Group, in the period 1995-2012...
November 23, 2017: Acta Oncologica
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