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https://www.readbyqxmd.com/read/29121639/a-subset-of-sweet-sensing-neurons-identified-by-ir56d-are-necessary-and-sufficient-for-fatty-acid-taste
#1
John M Tauber, Elizabeth B Brown, Yuanyuan Li, Maria E Yurgel, Pavel Masek, Alex C Keene
Fat represents a calorically potent food source that yields approximately twice the amount of energy as carbohydrates or proteins per unit of mass. The highly palatable taste of free fatty acids (FAs), one of the building blocks of fat, promotes food consumption, activates reward circuitry, and is thought to contribute to hedonic feeding underlying many metabolism-related disorders. Despite a role in the etiology of metabolic diseases, little is known about how dietary fats are detected by the gustatory system to promote feeding...
November 9, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/29108066/estimates-of-genetic-parameters-genetic-trends-and-inbreeding-in-a-crossbred-dairy-sheep-research-flock-in-the-united-states
#2
T W Murphy, Y M Berger, P W Holman, M Baldin, R L Burgett, D L Thomas
For the past 2 decades, the Spooner Agriculture Research Station (ARS) of the University of Wisconsin-Madison operated the only dairy sheep research flock in North America. The objectives of the present study were to 1) obtain estimates of genetic parameters for lactation and reproductive traits in dairy ewes, 2) estimate the amount of genetic change in these traits over time, and 3) quantify the level of inbreeding in this flock over the last 20 yr. Multiple-trait repeatability models (MTRM) were used to analyze ewe traits through their first 6 parities...
October 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/29089844/cheese-as-functional-food-the-example-of-parmigiano-reggiano-and-grana-padano
#3
REVIEW
Andrea Summer, Paolo Formaggioni, Piero Franceschi, Federica Di Frangia, Federico Righi, Massimo Malacarne
Italian hard cooked types of cheese, like Parmigiano Reggiano and Grana Padano, are characterised by positive nutritional qualities. In fact, they contain substances that have particular biological activities, and therefore they can be fully considered, according to the definition given by the European Unit, as 'functional' foods. This short review concisely describes these components and the beneficial effects related to their activities. The description of the biologically active components has been organised in the following paragraphs: protein and peptides, fat and lipids, carbohydrates and prebiotics, probiotic bacteria, vitamins, mineral salts, and components of dairy products active in disease prevention...
September 2017: Food Technology and Biotechnology
https://www.readbyqxmd.com/read/29072166/effect-of-an-intradialytic-protein-rich-meal-intake-in-nutritional-and-body-composition-parameters-on-hemodialysis-patients
#4
Cristina Caetano, Ana Valente, Francisco Jorge Silva, Jorge Antunes, Cristina Garagarza
BACKGROUND AND AIMS: Protein intake is a key point to maintain an adequate nutritional status in hemodialysis (HD) patients. There are some studies that confirm the positive influence of intradialytic oral nutritional supplementation in several nutritional parameters in HD patients. The aim of this study was to evaluate the effect of an intradialytic protein rich meal in nutritional and body composition parameters on HD patients. METHODS: This was a 6-months single center non-randomized study with 99 patients in HD from one Nephrocare dialysis unit in Portugal...
August 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29068397/diet-quality-associated-with-total-sodium-intake-among-us-adults-aged-%C3%A2-18-years-national-health-and-nutrition-examination-survey-2009-2012
#5
Carla I Mercado, Mary E Cogswell, Cria G Perrine, Cathleen Gillespie
Diet quality or macronutrient composition of total daily sodium intake (dNa) <2300 mg/day in the United States (US) is unknown. Using data from 2011-2014 NHANES (National Health and Nutrition Examination Survey), we examined 24-h dietary recalls (n = 10,142) from adults aged ≥18 years and investigated how diet composition and quality are associated with dNa. Diet quality was assessed using components of macronutrients and Healthy Eating Index 2010 (HEI-2010). Associations were tested using linear regression analysis adjusted for total energy (kcal), age, gender, and race/ethnicity...
October 25, 2017: Nutrients
https://www.readbyqxmd.com/read/29056891/polygala-tenuifolia-extract-inhibits-lipid-accumulation-in-3t3-l1-adipocytes-and-high-fat-diet-induced-obese-mouse-model-and-affects-hepatic-transcriptome-and-gut-microbiota-profiles
#6
Chun-Chung Wang, Jui-Hung Yen, Yi-Cheng Cheng, Chia-Yu Lin, Cheng-Ta Hsieh, Rung-Jiun Gau, Shu-Jiau Chiou, Hwan-You Chang
Obesity, the excessive accumulation of lipids in the body, is closely associated with many prevalent human disorders. Continued efforts to identify plant extracts that exhibit anti-obesity effects have drawn much attention. This study investigated whether a Polygala tenuifolia extract (PTE) possesses anti-obesity activity and how PTE may affect liver gene expression and gut microbiota. We used 3T3-L1 adipocytes and a high-fat diet-induced obese mouse model to determine the effects of PTE on lipid accumulation...
2017: Food & Nutrition Research
https://www.readbyqxmd.com/read/29053841/meat-quality-traits-and-proteome-profile-of-woody-broiler-breast-pectoralis-major-meat
#7
K Cai, W Shao, X Chen, Y L Campbell, M N Nair, S P Suman, C M Beach, M C Guyton, M W Schilling
Woody breast meat has recently become prevalent in the broiler industry in both the United States and European Union. Recent publications have described the meat quality characteristics of woody breast meat as having hardened areas and pale ridge-like bulges at both the caudal and cranial regions of the breast. The present study investigated the meat quality (pH, color, cooking loss, and shear force) and protein quality characteristics (protein and salt-soluble protein content) in woody breast meat as compared to normal breast meat...
October 5, 2017: Poultry Science
https://www.readbyqxmd.com/read/29051826/apparent-and-standardized-ileal-nutrient-digestibility-of-broiler-diets-containing-varying-levels-of-raw-full-fat-soybean-and-microbial-protease
#8
Mammo M Erdaw, Rider A Perez-Maldonado, Paul A Iji
BACKGROUND: Although soybean meal (SBM) is excellent source of protein in diets for poultry, it is sometimes inaccessible, costly and fluctuates in supply. The SBM can partially be replaced by full-fat SBM, but the meals prepared from raw full-fat soybean contain antinutritional factors. To avoid the risk of antinutritional factors, heat treatment is always advisable, but either excessive or under heating the soybean could negatively affect the quality. However, the potential for further improvement of SBM by supplementing with microbial enzymes has been suggested by many researchers...
2017: Journal of Animal Science and Technology
https://www.readbyqxmd.com/read/29047209/effects-of-cryopreservation-on-adipose-tissue-derived-microvascular-fragments
#9
Matthias W Laschke, Philipp Karschnia, Claudia Scheuer, Alexander Heß, Wolfgang Metzger, Michael D Menger
Adipose tissue-derived microvascular fragments (ad-MVF) are effective vascularization units for tissue engineering. They rapidly reassemble into new microvascular networks after seeding on scaffolds and subsequent in vivo implantation. Herein, we analyzed whether the vascularization capacity of ad-MVF is affected by cryopreservation. Ad-MVF were isolated from the epididymal fat pads of C57BL/6 mice and cryopreserved for 7 days to compare their morphology, viability, cellular composition and protein expression with freshly isolated control ad-MVF...
October 19, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/29018628/combined-moderate-and-high-intensity-exercise-with-dietary-restriction-improves-cardiac-autonomic-function-associated-with-a-reduction-in-central-and-systemic-arterial-stiffness-in-obese-adults-a-clinical-trial
#10
Min Hu, Shen Wang, Dan Wang, Qinhao Lai, Xiaoying Chen, Shiwei Duan, Mengke Zhao, Junhao Huang
OBJECTIVE: The present study aimed to assess the effects of exercise with dietary restriction on cardiac autonomic activity, arterial stiffness, and cardiovascular biomarkers in obese individuals. METHODS: Seventeen obese adults completed an 8-week exercise and dietary program. Anthropometry, body composition, and multiple biochemical markers were measured. We used carotid-femoral pulse wave velocity (cfPWV), brachial-ankle pulse wave velocity (baPWV), central blood pressure, and augmentation index (AIx) to assess arterial stiffness...
2017: PeerJ
https://www.readbyqxmd.com/read/28978343/dietary-food-patterns-and-glucose-insulin-homeostasis-a-cross-sectional-study-involving-24-182-adult-americans
#11
Mohsen Mazidi, Andre Pascal Kengne, Dimitri P Mikhailidis, Peter P Toth, Kausik K Ray, Maciej Banach
AIM: To investigate the association of major dietary patterns with glucose and insulin homeostasis parameters in a large American sample. The association between dietary patterns (DP) derived via principal components analysis (PCA), with glucose/insulin homeostasis parameters was assessed. The likelihood of insulin resistance (IR) across the DPs quarters was also explored. METHOD: The United States National Health and Nutrition Examination Survey (NHANES) participants during 2005-2012 were included if they underwent measurement of dietary intake as well as glucose and insulin homeostasis parameters...
October 4, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28977604/metformin-affects-cortical-bone-mass-and-marrow-adiposity-in-diet-induced-obesity-in-male-mice
#12
Sheila Bornstein, Michele Moschetta, Yawara Kawano, Antonio Sacco, Daisy Huynh, Daniel Brooks, Salomon Manier, Heather Fairfield, Carolyne Falank, Aldo M Roccaro, Kenichi Nagano, Roland Baron, Mary Bouxein, Calvin Vary, Irene M Ghobrial, Clifford J Rosen, Michaela R Reagan
Obesity during maturation can affect the growing skeleton directly and indirectly, although these effects and the mechanisms behind them are not fully understood. Our objective was to determine how a high-fat diet with or without metformin treatment affects skeletal development. We also sought to characterize changes that occur in white adipose tissue, circulating metabolites, lipids, and gut microbiota. A diet-induced obesity C57BL/6J mouse model was used to test the effects of obesity and metformin on bone using bone histomorphometry and microcomputed tomography...
October 1, 2017: Endocrinology
https://www.readbyqxmd.com/read/28976927/socioeconomic-inequities-in-diet-quality-and-nutrient-intakes-among-australian-adults-findings-from-a-nationally-representative-cross-sectional-study
#13
Katherine M Livingstone, Dana Lee Olstad, Rebecca M Leech, Kylie Ball, Beth Meertens, Jane Potter, Xenia Cleanthous, Rachael Reynolds, Sarah A McNaughton
Poor diet may represent one pathway through which lower socioeconomic position (SEP) leads to adverse health outcomes. This study examined the associations between SEP and diet quality, its components, energy, and nutrients in a nationally representative sample of Australians. Dietary data from two 24-h recalls collected during the cross-sectional Australian Health Survey 2011-13 (n = 4875; aged ≥ 19 years) were analysed. Diet quality was evaluated using the Dietary Guidelines Index (DGI). SEP was assessed by index of area-level socioeconomic disadvantage, education level, and household income...
October 4, 2017: Nutrients
https://www.readbyqxmd.com/read/28940796/gene-activated-tissue-grafts-for-sustained-bone-morphogenetic-protein-2-delivery-and-bone-engineering-is-muscle-with-fascia-superior-to-muscle-and-fat
#14
Bin Ren, Volker M Betz, Christian Thirion, Michael Salomon, Volkmar Jansson, Peter E Müller, Oliver B Betz
BACKGROUND: Previously, we have presented an expedited strategy for sustained delivery of BMP-2 to bone lesions based on the implantation of gene activated fat and muscle fragments. The aim of the present in vitro experiments was to evaluate the potential of muscle with fascia as a BMP-2 delivering osteo-regenerative implant in comparison to fat tissue and muscle alone. METHODS: Subcutaneous fat, muscle and muscle with fascia were harvested from Fischer 344 rats...
September 21, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28935851/comparative-analysis-of-the-microbial-communities-in-raw-milk-produced-in-different-regions-of-korea
#15
In Seon Kim, Yoo Kyung Hur, Eun Ji Kim, Young-Tae Ahn, Jong Geun Kim, Yun-Jaie Choi, Chul Sung Huh
OBJECTIVE: The control of psychrotrophic bacteria causing milk spoilage and illness due to toxic compounds is an important issue in the dairy industry. In South Korea, Gangwon-do province is one of the coldest terrains in which eighty percent of the area is mountainous regions, and mainly plays an important role in the agriculture and dairy industries. The purposes of this study were to analyze the indigenous microbiota of raw milk in Gangwon-do and accurately investigate a putative microbial group causing deterioration in milk quality...
November 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28923309/altered-penile-caveolin-expression-in-diabetes-potential-role-in-erectile-dysfunction
#16
Jay Parikh, Alice Zemljic-Harpf, Johnny Fu, Dimosthenis Giamouridis, Tung-Chin Hsieh, Adam Kassan, Karnam S Murthy, Valmik Bhargava, Hemal H Patel, M Raj Rajasekaran
BACKGROUND: The pathophysiology of increased severity of erectile dysfunction in men with diabetes and their poor response to oral pharmacotherapy are unclear. Defective vascular endothelium and consequent impairment in the formation and action of nitric oxide (NO) are implicated as potential mechanisms. Endothelial NO synthase, critical for NO generation, is localized to caveolae, plasma membrane lipid rafts enriched in structural proteins, and caveolins. Type 2 diabetes mellitus (T2DM)-induced changes in caveolin expression are recognized to play a role in cardiovascular dysfunction...
October 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28904479/effect-of-fat-based-versus-carbohydrate-based-enteral-feeding-on-glycemic-control-in-critically-ill-patients-a-randomized-clinical-trial
#17
Mahdieh Nourmohammadi, Omid Moradi Moghadam, Mohammad Niakan Lahiji, Sevak Hatamian, Zahra Vahdat Shariatpanahi
BACKGROUND AND AIMS: The aim of this study was to evaluate the preventive effects of high-fat enteral feeding on glycemic control and clinical outcomes in critically ill patients: a randomized clinical trial. MATERIALS AND METHODS: This study was done on 42 normoglycemic patients admitted to Intensive Care Unit (ICU). Patients were randomly classified into three groups of 14 each. Control group (A) received carbohydrate-based diet (protein: 20%, fat: 30%, and carbohydrate: 50%), study groups received two types of high-fat diet; Group B (protein: 20%, fat: 45% including half of olive oil and half sunflower oil, and carbohydrate: 35%); and Group C (protein: 20%, fat: 45% including sunflower oil, and carbohydrate: 35%) in the first 48 h of admission...
August 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28889156/oxidative-damage-and-associated-inflammatory-risk-factors-in-obese-emirati-women-body-mass-index-versus-waist-circumference
#18
Salah Gariballa, Juma Alkaabi, Javed Yasin, Awad Al Essa
OBJECTIVES: To establish whether body mass index (BMI) or waist circumference (WC) is a better predictor of cardio metabolic risk factors that are associated with increased visceral fat among obese women from the United Arab Emirates (UAE). METHODS: In this  cross-sectional study, 333 obese subjects visiting community health centers in Al Ain city, UAE, were recruited between 2012 and 2015. After a written consent subjects had anthropometric, clinical and biochemical measurements...
September 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28888600/effects-of-egg-yolk-inclusion-milk-replacer-feeding-rate-and-low-starch-pelleted-or-high-starch-texturized-starter-on-holstein-calf-performance-through-4-months-of-age
#19
T S Dennis, F X Suarez-Mena, T M Hill, J D Quigley, R L Schlotterbeck
The objectives of this research were to evaluate milk replacer (MR) feeding rates, alternative protein and fat sources in MR, and calf starter starch concentration and their effects on calf performance to 4 mo of age. Male Holstein calves (42.6 ± 1.2 kg of body weight; n = 192) were assigned at 3 d of age to 1 of 8 treatments in a randomized complete block design with a 2 × 2 × 2 factorial arrangement of treatments. Factors tested from d 0 to 56 (nursery) were low or high MR feeding rates, 0 or 10% inclusion of spray-dried egg yolks in MR, and low- or high-starch calf starter...
November 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28869073/association-of-the-rs10830963-polymorphism-in-melatonin-receptor-type-1b-mtnr1b-with-metabolic-response-after-weight-loss-secondary-to-a-hypocaloric-diet-based-in-mediterranean-style
#20
Daniel Antonio de Luis, Olatz Izaola, David Primo, R Aller
BACKGROUND & AIMS: Some genetic variants within MTNR1B were related with fasting glucose levels or the increased prevalence of diabetes mellitus and obesity. The aims of the present investigation were to determine the influence of rs10830963 MTNR1B variant in relation to body weight loss, insulin resistance and adipokine levels in response to a hypocaloric diet with Mediterranean pattern. METHODS: A Caucasian population of 80 obese patients was studied before and after 12 weeks on a hypocaloric diet...
August 23, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
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