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Diabetic foot ulcer leukocytosis infection

Arkady Shklyar, Edward B Miller, Zvi Landau
UNLABELLED:  Background. The diabetic foot is a common site of infections that frequently result in significant patient morbidity and mortality. Antibiotic treatment is an important part of therapy with selection of the specific agent depending on the stage of ulceration. Recently, ertapenem has entered use as first line therapy for moderate to severe diabetic foot infections. The following prospective study recounts the experience of using ertapenem as tertiary salvage therapy following failure of first and second-line antibiotics...
June 2010: Wounds: a Compendium of Clinical Research and Practice
Jonathan C Baker, Jennifer L Demertzis, Nicholas G Rhodes, Daniel E Wessell, David A Rubin
Diabetes mellitus is increasingly prevalent and results in various clinically important musculoskeletal disorders affecting the limbs, feet, and spine as well as in widely recognized end-organ complications such as neuropathy, nephropathy, and retinopathy. Diabetic muscle ischemia-a self-limited disorder-may be confused with infectious or inflammatory myositis, venous thrombosis, or compartment syndrome. The absence of fever and leukocytosis, combined with the presence of bilaterally distributed lesions in multiple and often noncontiguous muscles in the legs, including the thighs, is suggestive of ischemia; by contrast, the presence of well-defined intramuscular abscesses with rimlike enhancement favors a diagnosis of infectious pyomyositis...
November 2012: Radiographics: a Review Publication of the Radiological Society of North America, Inc
Mohammad Zubair, Abida Malik, Jamal Ahmad
OBJECTIVE: Aim of this study was to evaluate the incidence and risk factors for amputation among patients with diabetic foot ulcer (DFU). RESEARCH DESIGN AND METHODS: We performed a prospective study of 162 DFU in patients treated in a multidisciplinary based diabetes and endocrinology centre of Jawaharlal Nehru Medical College of Aligarh Muslim University, Aligarh, India during the period of December 2008-March 2011. Detailed history and physical examination was carried out for every subject...
March 2012: Foot
D G Armstrong, L A Lavery, M Sariaya, H Ashry
The purpose of this article is to describe the frequency of leukocytosis and elevated erythrocyte sedimentation rate in a series of diabetics with acute foot infections and osteomyelitis due to neuropathic foot ulcerations. The authors reviewed the admission records of 28 type II diabetic patients admitted to University Hospital in San Antonio, Texas between January 1, 1990 and December 30, 1992 with acute osteomyelitis of the foot secondary to neuropathic ulceration. The mean white blood cell count on admission for all subjects studied was calculated at 11...
July 1996: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
G A Tannenbaum, F B Pomposelli, E J Marcaccio, G W Gibbons, D R Campbell, D V Freeman, A Miller, F W LoGerfo
The results of 56 vein bypasses to the dorsal pedal artery performed in 53 diabetic patients who were admitted with ischemic foot lesions complicated by infection were reviewed. All patients had one or more of the following: infected ulcers (73%), cellulitis (45%), osteomyelitis (29%), gangrene (20%), or abscess (2%). Organisms were cultured from 84% of patients (average 2.6, range 1 to 9 organisms per infection). Elevated temperature (greater than 37.7 degrees C) or leukocytosis (greater than 9.0 x 10(3)/ml) were seen in 13% and 50% of patients, respectively...
June 1992: Journal of Vascular Surgery
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