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Leukocytosis and infection

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https://www.readbyqxmd.com/read/28507842/pyoderma-gangrenosum-after-deep-inferior-epigastric-perforator-breast-reconstruction-systematic-review-and-case-report
#1
Justin T Zelones, John F Nigriny
BACKGROUND: Pyoderma gangrenosum (PG) is a rare skin disorder of the neutrophilic dermatoses spectrum that can mimic wound infections in surgical patients. PG after breast surgery has been reported but in limited amounts in autologous breast reconstruction patients. We present the first case of PG after a delayed bilateral deep inferior epigastric perforator flap breast reconstruction in the setting of systemic disease along with a systematic review. METHODS: PubMed, Ovid, and Web of Science were systematically searched to obtain cases of PG after autologous breast reconstruction...
April 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28501866/clinical-factors-associated-with-readmission-among-patients-with-lower-limb-cellulitis
#2
Amit Garg, Jonathan Lavian, Gloria Lin, Cristina Sison, Michael Oppenheim, Bonnie Koo
BACKGROUND: There is substantial allocation of resources directed towards evaluation and management of lower limb cellulitis (LLC) in the acute care setting. Readmission for LLC is poorly understood, and there is little evidence with which to identify patients at risk for readmission. OBJECTIVE: To describe demographics, comorbidities, admission vital signs, and laboratory markers of infection among patients with LLC who are readmitted, and to investigate which among these factors is associated with readmission...
May 13, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/28491193/indium-111-labeled-leukocyte-accumulation-in-extremity-soft-tissue-sarcoma
#3
Victor Fong, Lester Johnson
Nuclear medicine labeled leukocyte whole-body scintigraphy is commonly used to identify a source of infection in a patient with fever of unknown origin. White blood cells can also localize to other sites of inflammation, including sometimes tumors. A patient with a large myxofibrosarcoma in his left forearm was scanned due to chronic low-grade fever and persistent leukocytosis. This case demonstrates focal white blood cell activity in an extremity soft tissue sarcoma.
June 2017: Radiology case reports
https://www.readbyqxmd.com/read/28464021/predictive-value-of-clinical-and-laboratory-features-for-the-main-febrile-diseases-in-children-living-in-tanzania-a-prospective-observational-study
#4
Olga De Santis, Mary Kilowoko, Esther Kyungu, Willy Sangu, Pascal Cherpillod, Laurent Kaiser, Blaise Genton, Valérie D'Acremont
BACKGROUND: To construct evidence-based guidelines for management of febrile illness, it is essential to identify clinical predictors for the main causes of fever, either to diagnose the disease when no laboratory test is available or to better target testing when a test is available. The objective was to investigate clinical predictors of several diseases in a cohort of febrile children attending outpatient clinics in Tanzania, whose diagnoses have been established after extensive clinical and laboratory workup...
2017: PloS One
https://www.readbyqxmd.com/read/28454572/invasive-pulmonary-mucormycosis-rare-presentation-with-pulmonary-eosinophilia
#5
Taizou Hirano, Mitsuhiro Yamada, Kei Sato, Koji Murakami, Tokiwa Tamai, Yoshiya Mitsuhashi, Tsutomu Tamada, Hisatoshi Sugiura, Naomi Sato, Ryoko Saito, Junya Tominaga, Akira Watanabe, Masakazu Ichinose
BACKGROUND: Fungi can cause a variety of infectious diseases, including invasive mycosis and non-invasive mycosis, as well as allergic diseases. The different forms of mycosis usually have been described as mutually exclusive, independent entities, with few descriptions of overlapping cases. Here, we describe the first reported case of a patient with the complication of pulmonary eosinophilia in the course of invasive mucormycosis. CASE PRESENTATION: A 74-year-old Japanese man with asthma-COPD overlap underwent emergency surgery for a ruptured abdominal aortic aneurysm...
April 28, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28446282/-effects-of-different-dosages-of-rhg-csf-on-duration-of-aleucocytosis-and-leukocytes-level-after-chemotherapy-of-patients-with-hematologic-malignancies
#6
Yue-Li Gu, Xi-Chun Xiao, Shuo Yang
OBJECTIVE: To compare the effects of different dosages of rhG-CSF on duration of aleucocytosis and white blood cell counts after chemotherapy of patients with hematologic malignancies. METHODS: Ninety patients in our hospital from December 2011 to June 2016 were chosen as study objects, and all of them were divided into 3 groups: group A (rhG-CSF 200 µg/m(2)), group B(rhG-CSF 300 µg/m(2)) and group C(rhG-CSF 400 µg/m(2)); 30 patients from January 2004 to January 2007 were chosen as control(control group)...
April 2017: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/28444873/hematologic-hepatic-and-renal-function-changes-in-hospitalized-patients-with-middle-east-respiratory-syndrome-coronavirus
#7
J A Al-Tawfiq, K Hinedi, S Abbasi, M Babiker, A Sunji, M Eltigani
BACKGROUND: There are no longitudinal data on the changes in hematologic, hepatic, and renal function findings in patients with Middle East respiratory syndrome coronavirus (MERS-CoV) infection. METHODS: This is a retrospective cohort study of 16 MERS-CoV patients, to describe the hematological, hepatic, and renal findings of patients with MERS-CoV. RESULTS: During the 21 days of observation, there was no significant change in the hepatic panel or creatinine tests...
April 26, 2017: International Journal of Laboratory Hematology
https://www.readbyqxmd.com/read/28439680/microbiological-evaluation-of-infected-pelvic-lymphocele-after-robotic-prostatectomy-potential-predictors-for-culture-positivity-and-selection-of-the-best-empirical-antimicrobial-therapy
#8
Alaa Hamada, Catalina Hwang, Jorge Fleisher, Ingolf Tuerk
OBJECTIVES: To examine symptomatology and microbiology of infected lymphocele (LC) post-robotic-assisted radical prostatectomy and pelvic lymph node dissection (PLND) and to assess for potential predictors for LC fluid culture positivity. Secondly, to provide general recommendations about use of select antimicrobial therapy. METHODS: This was a single-center, IRB-approved, retrospective, case series review conducted between October 2008 and October 2014. Data included symptomatology, microbiology of symptomatic LC in men post-robotic prostatectomy and PLND...
April 24, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28435490/correlation-of-physical-exam-findings-with-fever-in-patients-with-skin-and-soft-tissue-infections
#9
Jillian Mongelluzzo, Brian Tu, Barbara Grimes, Sharvina Ziyeh, Jonathan Fortman, Jersey Neilson, Robert M Rodriguez
INTRODUCTION: The objectives of this study were to determine the prevalence of fever in adult ED patients with skin and soft tissue infections (SSTI) and to determine which, if any, physical exam, radiograph and laboratory test findings were associated with fever. METHODS: We conducted a prospective, observational study at an urban county trauma center of adults who presented to the ED for evaluation of suspected SSTI. ED providers measured area of erythema and induration using a tape measure, and completed data sheets indicating comorbid conditions and the presence or absence of physical exam findings...
April 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28419015/an-unanticipated-complication-of-atopic-dermatitis
#10
Megan E MacGillivray, Loretta Fiorillo
An infant with a history of atopic dermatitis presented to the emergency department on 5 occasions with flulike symptoms. Eventually, this child presented with signs of infection and increased intracranial pressure: fever, bulging anterior fontanel, and leukocytosis. A computed tomography scan identified a large frontal lobe brain abscess. The abscess was surgically drained; culture was positive for Staphylococcus aureus. The initial source of the infected brain abscess was explored. Ultimately, it was thought to be secondary to impetiginized atopic dermatitis, an unusual but serious consequence of a common skin condition...
April 18, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28414664/gonococcal-endocarditis-the-gift-that-stops-giving-an-uncommon-presentation-of-a-common-disease
#11
G Olayemi, M Oferczak, A Elagizi, I El-Abbassi, M Eschete, J Crowe
INTRODUCTION: Gonorrhea is the 2nd most common sexually transmitted disease in the US with 800,000 cases of gonorrhea each year. Disseminated gonorrhea infection occurs in 0.5 percent - 3 percent of these patients and is more frequent in woman younger than 40 years of age. CASE: A 36 year old woman with a history of polysubstance abuse presented with 10 day history of feeling generally unwell. At presentation, vitals were remarkable for tachycardia and hypotension...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28386783/postoperative-leukocyte-changes-in-facial-fracture-patients-a-randomized-prospective-study-with-short-term-dexamethasone
#12
Johanna Snäll, Jyrki Törnwall, Anna Liisa Suominen, Hanna Thorén
PURPOSE: We investigated leukocyte changes in facial fracture patients undergoing surgery. Of specific interest was the effect of perioperative dexamethasone on leukocyte changes. METHODS: Facial fracture patients were randomized to receive perioperatively a total dose of 30 mg of dexamethasone, whereas patients in the control group received no glucocorticoid. All patients received antibiotics until postoperative days 7-10. Leukocyte count was measured on postoperative days 1 and 2...
June 2017: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28386144/self-healing-juvenile-cutaneous-mucinosis
#13
Beata Kołodziejczyk, Agnieszka Gazda, Elżbieta Hernik, Izabela Szczygielska, Lidia Rutkowska-Sak, Marta Legatowicz Koprowska
Girl, aged 4 years old, began the disease with pain of the lower extremities, fever up to 38°C and signs of upper airway infection. Then the patient developed oedema and redness of the whole face, thickened skin, subcutaneous nodular foldings of the frontal, occipital, cervical and axillary regions, extensor areas of the joints; fine, hard whitish nodules in the frontal region and over interphalangeal joints of the hands, pruritus; oedemas of the ankles, knees and joints of the hands, cervical lymphadenopathy and hepatomegaly...
2017: Reumatologia
https://www.readbyqxmd.com/read/28381313/influence-of-genetic-background-on-hematologic-and-histopathologic-alterations-during-acute-granulocytic-anaplasmosis-in-129-svev-and-c57bl-6j-mice-lacking-type-i-and-type-ii-interferon-signaling
#14
Jennifer L Johns, Marielle L Discipulo, Amanda L Koehne, Kaitlin A Moorhead, Claude M Nagamine
The role of host type I IFN signaling and its interaction with other immune pathways during bacterial infections is incompletely understood. Type II IFN signaling plays a key role during numerous bacterial infections including granulocytic anaplasmosis (GA) caused by Anaplasma phagocytophilum infection. The function of combined type I and type II IFN signaling and their potential synergism during GA and similar tick-borne diseases is a topic of current research investigation. The goal of this study was to evaluate 2 mouse models of absent type I/type II IFN signaling in experimental A...
March 1, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/28377567/chronic-granulomatous-disease-presenting-as-aspergillus-fumigatus-pneumonia-in-a-previously-healthy-young-woman
#15
David Williams, Dipen Kadaria, Amik Sodhi, Roy Fox, Glenn Williams, Stephen Threlkeld
BACKGROUND Chronic Granulomatous Disease (CGD) is a rare immunodeficiency disease caused by a genetic defect in the NADPH (nicotinamide adenine dinucleotide phosphate) oxidase enzyme, resulting in increased susceptibility to bacterial and fungal infections. The inheritance can be X-linked or autosomal recessive. Patients usually present with repeated infections early in life. We present an unusual case of a 23-year-old patient diagnosed with CGD. CASE REPORT A 23-year-old white woman with no previous history of recurrent infections presented with complaints of fever, shortness of breath, and diffuse myalgia...
April 5, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28376777/assessment-of-safety-and-efficacy-against-bordetella-pertussis-of-a-new-tetanus-reduced-dose-diphtheria-acellular-pertussis-vaccine-in-a-murine-model
#16
Hyo Jin Kwon, Seung Beom Han, Bo Ram Kim, Kyu Ri Kang, Dong Ho Huh, Gi Sub Choi, Dong Ho Ahn, Jin Han Kang
BACKGROUND: Tetanus-reduced dose diphtheria-acellular pertussis (Tdap) vaccination during adolescence was introduced in response to the resurgence of pertussis in various countries. A new Tdap vaccine was manufactured in Korea as a countermeasure against a predicted Tdap vaccine shortage. This study was performed to evaluate the immunogenicity, safety, and protection efficacy against Bordetella pertussis of the new Tdap vaccine in a murine model. METHODS: Four-week-old BABL/c mice were used for assessment of immunogenicity and protection efficacy...
April 4, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28363494/clinical-and-endoscopic-features-in-patients-with-hospital-acquired-diarrhea-associated-with-clostridium-difficile-infection
#17
J A Velarde Ruiz-Velasco, J M Aldana-Ledesma, M A Ibarra-Estrada, S A Aguirre Díaz, J A Fernández-Ramírez, F Cárdenas-Lara, F Álvarez López, L E Rodríguez-Noriega, H R Pérez-Gómez, M R Morfín-Otero
BACKGROUND AND AIMS: Clostridium difficile (CD) is the leading cause of hospital-acquired diarrhea. Clinical and endoscopic findings are poorly described in our country. The aim of this study is to depict those findings. MATERIAL AND METHODS: Prospective cohort study, which included patients with CD associated hospital-acquired diarrhea, diagnosed by means of fecal PCR and testing for the presence of hypervirulent strain NAP027. We analyzed clinical and endoscopic features, as well as the variables associated with severe disease...
March 28, 2017: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/28358605/therapeutic-use-of-regional-limb-perfusion-in-a-chicken
#18
Cameron M Ratliff, Bianca A Zaffarano
A 2-year-old, 3.8-kg male Rhode Island red rooster was examined for lameness and progressive swelling of the right foot of several month's duration. Radiographs of the right foot demonstrated soft tissue swelling and a smoothly marginated periosteal reaction evident of inflammation affecting the bones. Results of a complete blood count showed a moderate leukocytosis and an elevated total protein concentration. Systemic antibiotic and anti-inflammatory therapy was started, but the bird had not improved at recheck examination...
March 2017: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/28356527/chemokine-receptor-ccr7-restricts-fatal-west-nile-virus-encephalitis
#19
Susana V Bardina, Julia A Brown, Daniela Michlmayr, Kevin W Hoffman, Janet Sum, Alexander G Pletnev, Sergio A Lira, Jean K Lim
West Nile virus (WNV) is a mosquito-transmitted flavivirus that can cause debilitating encephalitis. To delineate the mechanisms behind this pathology, we studied Ccr7-deficient mice, which afforded us the capacity to study infection in mice with disrupted peripheral cellular trafficking events. The loss of Ccr7 resulted in an immediate pan-leukocytosis that remained elevated throughout the infection. This leukocytosis resulted in a significant enhancement of leukocyte accumulation within the central nervous system (CNS)...
May 15, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28355360/helicobacter-pylory-infection-in-patients-with-esophageal-squamous-cell-carcinoma
#20
Omer Bilgehan Poyrazoglu, Ahmet Cumhur Dulger, Bilge Sumbul Gultepe
OBJECTIVE: Esophageal squamous cell carcinoma is one of the most common esophageal diseases in the developing world, but the relationship between esophageal squamous cell carcinoma and Helicobacter pylori infection remains a neglected topic. The primary objective of this study was to determine the association between Helicobacter pylori infection and esophageal squamous cell carcinoma. A second purpose was to determine the incidence and factors associated with Helicobacter pylori infection following esophagectomy...
March 2017: Clinics
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