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https://www.readbyqxmd.com/read/28506403/an-on-road-study-of-sleepiness-in-split-shifts-among-city-bus-drivers
#1
Anna Anund, Carina Fors, Jonas Ihlström, Göran Kecklund
Bus drivers often work irregular hours or split shifts and their work involves high levels of stress. These factors can lead to severe sleepiness and dangerous driving. This study examined how split shift working affects sleepiness and performance during afternoon driving. An experiment was conducted on a real road with a specially equipped regular bus driven by professional bus drivers. The study had a within-subject design and involved 18 professional bus drivers (9 males and 9 females) who drove on two afternoons; one on a day in which they had driven early in the morning (split shift situation) and one on a day when they had been off duty until the test (afternoon shift situation)...
May 12, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28495465/the-effect-of-blue-enriched-white-light-on-cognitive-performances-and-sleepiness-of-night-shift-workers-a-field-study
#2
Majid Motamedzadeh, Rostam Golmohammadi, Reza Kazemi, Rashid Heidarimoghadam
INTRODUCTION: Night-shift works are basically accompanied by reduced cognitive performance, sleepiness, and higher possibility for human error and related incidents. It is therefore crucial to improve individuals' performance and alertness in sensitive places like industries' control room with the ultimate goal of increasing efficiency and reducing the number of possible incidents. Previous research has indicated that blue light is a critical cue for entraining circadian rhythm. As a result, the present study was an attempt to investigate whether blue-enriched white light illumination was a practical strategy to decrease sleepiness and improve cognitive performance during night shifts...
May 8, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28476552/preceding-national-early-warnings-scores-among-in-hospital-cardiac-arrests-and-their-impact-on-survival
#3
Daniel Roberts, Therese Djärv
OBJECTIVES: In-hospital cardiac arrests (IHCAs) are often preceded by abnormal vital signs. Preceding abnormal vital signs might lower the physiological reserve capacity and therefore decrease survival after an IHCA. AIM: To assess the preceding national early warning score (NEWS) and its relation to survival after an IHCA. MATERIAL AND METHODS: All patients ≥18years suffering an IHCA at Karolinska University Hospital between 1st January 2014 and 31st December 2015 were included...
April 28, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28470767/sleep-wake-rhythm-disturbances-and-perceived-sleep-in-adolescent-chronic-fatigue-syndrome
#4
Maria Pedersen, Mirjam Ekstedt, Milada C Småstuen, Vegard B Wyller, Dag Sulheim, Even Fagermoen, Anette Winger, Edvard Pedersen, Harald Hrubos-Strøm
Chronic fatigue syndrome (CFS) is characterized by long-lasting, disabling and unexplained fatigue that is often accompanied by unrefreshing sleep. The aim of this cross-sectional study was to investigate sleep-wake rhythm and perceived sleep in adolescent CFS patients compared to healthy individuals. We analysed baseline data on 120 adolescent CFS patients and 39 healthy individuals included in the NorCAPITAL project. Activity measures from a uniaxial accelerometer (activPAL) were used to estimate mid-sleep time (mid-point of a period with sleep) and time in bed...
May 4, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28467102/interpersonal-violence-early-life-adversity-and-suicidal-behavior-in-hypersexual-men
#5
Andreas Chatzittofis, Josephine Savard, Stefan Arver, Katarina Görts Öberg, Jonas Hallberg, Peter Nordström, Jussi Jokinen
Background and aims There are significant gaps in knowledge regarding the role of childhood adversity, interpersonal violence, and suicidal behavior in hypersexual disorder (HD). The aim of this study was to investigate interpersonal violence in hypersexual men compared with healthy volunteers and the experience of violence in relation to suicidal behavior. Methods This case-control study includes 67 male patients with HD and 40 healthy male volunteers. The Childhood Trauma Questionnaire - Short Form (CTQ-SF) and the Karolinska Interpersonal Violence Scale (KIVS) were used for assessing early life adversity and interpersonal violence in childhood and in adult life...
May 3, 2017: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/28463867/measuring-fatigue-in-triage-a-pilot-study
#6
Bryn McMahon, John Hudson, Judy Prewitt, Margaret J Carman, Monica Engleson
: Given the critical nature of triage in facilitating emergency department (ED) functions, an understanding of the factors that impact triage nurses' ability to accurately assign triage scores and the ways in which these factors may affect various patient outcomes is extremely important; yet, there exists a paucity of such research in the literature. To further develop this knowledge base, an investigation of triage nurse fatigue and the role it may play in the ability to accurately assign triage scores was developed...
April 2017: Advanced Emergency Nursing Journal
https://www.readbyqxmd.com/read/28451534/determination-the-levels-of-subjective-and-observer-rating-of-drowsiness-and-their-associations-with-facial-dynamic-changes
#7
Mohsen Poursadeghiyan, Adel Mazloumi, Gebraeil Nasl Saraji, Ali Niknezhad, Arash Akbarzadeh, Mohammad Hossein Ebrahimi
BACKGROUND: We determined the levels of subjective and observer drowsiness and facial dynamics changes. METHODS: This experimental study was done in the virtual reality laboratory of Khaje-Nasir Toosi University of Technology in 2015. Facial dynamics changes like changes in eyes, mouth and eyebrows were surveyed on twenty-five drivers in 2015byKSS (Karolinska Sleepiness Scale) and ORD (Observer Rating of Drowsiness). ANOVA Repeated Measure and MANOVA Repeated Measure tests were used for data analysis...
January 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28440015/hypertriglyceridemia-during-asparaginase-treatment-in-children-with-acute-lymphoblastic-leukemia-correlates-with-antithrombin-activity-in-adolescents
#8
Lisa Persson, Arja Harila-Saari, Ida Hed Myrberg, Mats Heyman, Anna Nilsson, Susanna Ranta
BACKGROUND: Asparaginase (ASP) is a cornerstone in the treatment of acute lymphoblastic leukemia (ALL). It is also known for its ability to cause side effects, such as allergy and pancreatitis, as well as lipid and coagulation disturbances. The most important laboratory abnormalities are hypertriglyceridemia (HTG) and low antithrombin (AT). HTG is usually considered to be transient and benign in children with ALL, whereas low AT activity predisposes to thrombosis. Studies on the incidence and significance of HTG in children with ALL are scarce, and their findings have not always been congruent...
April 25, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28420278/audiometric-features-in-young-adults-with-turner-syndrome
#9
Åsa Bonnard, Christina Hederstierna, Rusana Bark, Malou Hultcrantz
OBJECTIVE: Hearing loss (HL) is a known problem in adults with Turner syndrome (TS). The aim of this study was to investigate audiometric features in young adults with TS and the extent of hearing aid provision. DESIGN: Patients were recruited from the Turner centre at Karolinska University Hospital. Analysis of audiograms was made in relation to hearing aid use, a Swedish normal hearing cohort and the need for hearing rehabilitation. STUDY SAMPLE: Sixty-four women with TS aged 25-38 years at the time of their audiological testing...
April 19, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28419388/daytime-sleepiness-increases-with-age-in-early-adolescence-a-sleep-restriction-dose-response-study
#10
Ian G Campbell, Christopher S Burright, Amanda M Kraus, Kevin J Grimm, Irwin Feinberg
Study Objectives: Daytime sleepiness increases across adolescence. This increase is commonly attributed to insufficient sleep durations resulting from increasingly limited time in bed. We tested the effects of 3 sleep schedules on daytime sleepiness and whether these effects changed with age in early adolescence. Methods: In 77 children ranging in age from 9.9 to 14 years, objective (multiple sleep latency test [MSLT]) and subjective (Karolinska sleepiness scale [KSS]) sleepiness was measured following 4 consecutive nights of either 7, 8...
May 1, 2017: Sleep
https://www.readbyqxmd.com/read/28413911/recurrence-rate-after-thoracoscopic-surgery-for-primary-spontaneous-pneumothorax
#11
Hanna H Dagnegård, Alice Rosén, Ulrik Sartipy, Per Bergman
OBJECTIVES: There is an on-going discussion regarding the recurrence rate after surgery for primary spontaneous pneumothorax by video assisted thoracic surgery (VATS) or by thoracotomy access. This study aimed to describe the recurrence rate, and to identify a possible learning curve, following surgery for primary spontaneous pneumothorax by VATS. DESIGN: All patients who underwent surgery for primary spontaneous pneumothorax by VATS at Karolinska University Hospital 2004-2013 were reviewed...
April 17, 2017: Scandinavian Cardiovascular Journal: SCJ
https://www.readbyqxmd.com/read/28391069/insulin-and-glucagon-in-plasma-and-cerebrospinal-fluid-in-suicide-attempters-and-healthy-controls
#12
Marie Bendix, Kerstin Uvnäs-Moberg, Maria Petersson, Viktor Kaldo, Marie Åsberg, Jussi Jokinen
Mental disorders and related behaviors such as suicidality and violence have been associated to dysregulation of e g carbohydrate metabolism. We hypothesized that patients after suicide attempt, compared to healthy controls, would have higher insulin and lower glucagon levels in plasma and cerebrospinal fluid and that these changes would be associated to violent behavior. Twenty-eight medication-free patients (10 women, 18 men), hospitalized after suicide attempt, and 19 healthy controls (7 women, 12 men) were recruited with the aim to study risk factors for suicidal behavior...
March 23, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28374555/understanding-cell-cycle-and-cell-death-regulation-provides-novel-weapons-against-human-diseases
#13
REVIEW
K G Wiman, B Zhivotovsky
Cell division, cell differentiation and cell death are the three principal physiological processes that regulate tissue homoeostasis in multicellular organisms. The growth and survival of cells as well as the integrity of the genome are regulated by a complex network of pathways, in which cell cycle checkpoints, DNA repair and programmed cell death have critical roles. Disruption of genomic integrity and impaired regulation of cell death may both lead to uncontrolled cell growth. Compromised cell death can also favour genomic instability...
May 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/28370590/normative-data-on-the-diurnal-pattern-of-the-karolinska-sleepiness-scale-ratings-and-its-relation-to-age-sex-work-stress-sleep-quality-and-sickness-absence-illness-in-a-large-sample-of-daytime-workers
#14
Torbjorn Åkerstedt, David Hallvig, Göran Kecklund
Self-rated sleepiness responds to sleep loss, time of day and work schedules. There is, however, a lack of a normative reference showing the diurnal pattern during a normal working day, compared with a day off, as well as differences depending on stress, sleep quality, sex, age and being sick listed. The present study sought to provide such data for the Karolinska Sleepiness Scale. Participants were 431 individuals working in medium-sized public service units. Sleepiness (Karolinska Sleepiness Scale, scale 1-9) was rated at six times a day for a working week and 2 days off (>90...
March 29, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28369804/positive-symptoms-associate-with-cortical-thinning-in-the-superior-temporal-gyrus-via-the-enigma-schizophrenia-consortium
#15
E Walton, D P Hibar, T G M van Erp, S G Potkin, R Roiz-Santiañez, B Crespo-Facorro, P Suarez-Pinilla, N E M Van Haren, S M C de Zwarte, R S Kahn, W Cahn, N T Doan, K N Jørgensen, T P Gurholt, I Agartz, O A Andreassen, L T Westlye, I Melle, A O Berg, L Mørch-Johnsen, A Faerden, L Flyckt, H Fatouros-Bergman, E G Jönsson, R Hashimoto, H Yamamori, M Fukunaga, A Preda, P De Rossi, F Piras, N Banaj, V Ciullo, G Spalletta, R E Gur, R C Gur, D H Wolf, T D Satterthwaite, L M Beard, I E Sommer, S Koops, O Gruber, A Richter, B Krämer, S Kelly, G Donohoe, C McDonald, D M Cannon, A Corvin, M Gill, A Di Giorgio, A Bertolino, S Lawrie, T Nickson, H C Whalley, E Neilson, V D Calhoun, P M Thompson, J A Turner, S Ehrlich
OBJECTIVE: Based on the role of the superior temporal gyrus (STG) in auditory processing, language comprehension and self-monitoring, this study aimed to investigate the relationship between STG cortical thickness and positive symptom severity in schizophrenia. METHOD: This prospective meta-analysis includes data from 1987 individuals with schizophrenia collected at seventeen centres around the world that contribute to the ENIGMA Schizophrenia Working Group. STG thickness measures were extracted from T1-weighted brain scans using FreeSurfer...
May 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28367741/two-swedish-screening-instruments-for-exhaustion-disorder-cross-sectional-associations-with-burnout-work-stress-private-life-stress-and-personality-traits
#16
Roger Persson, Kai Österberg, Njördur Viborg, Peter Jönsson, Artur Tenenbaum
AIMS: To examine the relationships of two screening instruments recently developed for assessment of exhaustion disorder (ED) with some other well-known inventories intended to assess ED-related concepts and self-reports of job demands, job control, job support, private life stressors, and personality factors. METHODS: A cross-sectional population sample ( n = 1355) completed: the Karolinska Exhaustion Disorder Scale (KEDS), Self-reported Exhaustion Disorder Scale (s-ED), Shirom-Melamed Burnout Questionnaire (SMBQ), Utrecht Work Engagement Scale (UWES-9), Job Content Questionnaire (JCQ), Big Five Inventory (BFI), and items concerning family-to-work interference and stress in private life...
March 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28361597/regional-recurrence-in-early-stage-i-ii-oral-tongue-cancer-a-single-institutional-study-and-review-of-the-literature
#17
Alexander Kamali, Caroline Gahm, Björn Palmgren, Linda Marklund, Martin Halle, Lalle Hammarstedt-Nordenvall
CONCLUSIONS: There is a high propensity for locoregional and isolated regional failure in stage II patients, even though treated with combined therapy. In stage I patients the risk of isolated regional failure was moderate, at levels below 10%. BACKGROUND: The neck treatment of early stages of oral tongue squamous cell carcinoma (OTSCC) are still debatable, considering that previous studies have produced diverting results. The purpose of this study is to report on the outcome of patients with stages I-II, with special respect to regional outcome...
February 22, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28352934/book-review-skin-and-psyche
#18
Liljana Mervic
Skin and Psyche by Klas Nordlind, Department of Dermatology Karolinska University Hospital, Solna, Stockholm, Sweden and Anna Zalewska-Janowska, Psychodermatology Department, Medical University of Łódź, Poland: Bentham Science Publishers, Sharjah, U.A.E, 2016, 239 pages, ISBN: 978-1-68108-302-5, eISBN 978-1-68108-301-8.
March 2017: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
https://www.readbyqxmd.com/read/28351784/risk-factor-analysis-of-anaphylactic-reactions-in-patients-with-systemic-mastocytosis
#19
Theo Gülen, Christopher Ljung, Gunnar Nilsson, Cem Akin
BACKGROUND: Systemic mastocytosis (SM) is a rare disorder of abnormal mast cells in at least 1 extracutaneous organ/tissue. Anaphylaxis is an acute, severe systemic hypersensitivity reaction, and a strong association between SM and anaphylaxis has been shown. However, not all patients with SM experience anaphylaxis. Presently, there are no predictive markers to discriminate patients with SM at high risk of anaphylaxis from those at low risk. OBJECTIVE: This study sought to determine risk factors for the occurrence of anaphylaxis in patients with SM...
March 25, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28343147/ethical-ramifications-of-the-paolo-macchiarini-case
#20
Jaime A Teixeira da Silva
The Paolo Macchiarini case has several ethical ramifications. Professor Macchiarini, formerly of the Karolinska Institutet (KI), became famous for the tracheal surgeries he conducted between 2008 and 2014. His rapid rise to fame was followed by an almost equally rapid fall from grace as official reports, articles in newspapers and television programmes revealed several aspects related to misconduct in his curriculum vitae, professional practices and publishing-related activity. Formal misconduct reports issued by four KI co-workers in late 2014, then again in 2016, coupled with social scandals, including the tricking of a famous US television newscaster into a false marriage, a previous arrest in Italy for apparent bribery, and acute narcissism, all tainted Macchiarini's legend...
March 15, 2017: Indian Journal of Medical Ethics
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