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https://www.readbyqxmd.com/read/28330209/biodegradation-of-real-petroleum-wastewater-by-immobilized-hyper-phenol-tolerant-strains-of-bacillus-cereus-in-a-fluidized-bed-bioreactor
#1
Aditi Banerjee, Aloke K Ghoshal
Microbial bioremediation of petroleum wastewater by phenol-degrading-bacteria holds promise in circumventing the issue of petroleum-spill related pollution. Herein, biodegradation of petroleum wastewater samples collected from oil refinery site was carried out in a fluidized bed bioreactor by Ca-alginate immobilized biomass of phenol-degrading strains of Bacillus cereus (AKG1 MTCC9817 and AKG2 MTCC9818). Degradation performance of the system was evaluated by measuring the changes in chemical oxygen demand (COD) and level of phenolic compounds in the wastewater samples during the microbial treatment...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28329436/prospective-evaluation-of-a-week-one-overnight-metyrapone-test-with-subsequent-dynamic-assessments-of-hypothalamic-pituitary-adrenal-axis-function-after-pituitary-surgery
#2
Katherine English, Warrick J Inder, Zara Weedon, Goce Dimeski, Jane Sorbello, Anthony W Russell, Emma L Duncan, Ross Cuneo
OBJECTIVE: To determine if an overnight metyrapone test (OMT) within the first week post pituitary surgery can definitively assess the hypothalamic-pituitary-adrenal (HPA) axis, compared with subsequent dynamic tests and glucocorticoid requirement at 6 months. DESIGN: Prospective study measuring morning cortisol levels on day 3 and 4 post-operatively, OMT day 5-7 and week 6, 250μg short Synacthen test (SST) week 6 and insulin tolerance test (ITT) week 7. PATIENTS AND MEASUREMENTS: Forty participants who underwent pituitary surgery at a single centre (Cushing's disease excluded) and were followed for at least 6 months...
March 22, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28328950/repeated-anaesthesia-with-isoflurane-and-medetomidine-midazolam-fentanyl-in-guinea-pigs-and-its-influence-on-physiological-parameters
#3
Sabrina Schmitz, Sabine Tacke, Brian Guth, Julia Henke
Repeated anaesthesia may be required in experimental protocols and in daily veterinary practice, but anaesthesia is known to alter physiological parameters in GPs (Cavia porcellus, GPs). This study investigated the effects of repeated anaesthesia with either medetomidine-midazolam-fentanyl (MMF) or isoflurane (Iso) on physiological parameters in the GP. Twelve GPs were repeatedly administered with MMF or Iso in two anaesthesia sets. One set consisted of six 40-min anaesthesias, performed over 3 weeks (2 per week); the anaesthetic used first was randomized...
2017: PloS One
https://www.readbyqxmd.com/read/28326618/comparative-study-of-hba1c-and-fasting-plasma-glucose-vs-the-oral-glucose-tolerance-test-for-diagnosis-of-diabetes-in-people-with-tuberculosis
#4
H Aftab, A Ambreen, M Jamil, P Garred, J H Petersen, S D Nielsen, I C Bygbjerg, D L Christensen
AIM: To compare HbA1c and fasting plasma glucose assessment, with the 2-h oral glucose tolerance test as reference, in screening for diabetes in people with turberculosis. METHODS: Individuals (N=268) with newly diagnosed smear-positive tuberculosis were screened for diabetes at a tertiary hospital in Lahore, Pakistan. Diabetes diagnosis was based on WHO criteria: thresholds were ≥ 48 mmol/mol (≥6.5%) for HbA1c and ≥7.0mmol/l for fasting plasma glucose. RESULTS: The proportion of participants diagnosed with diabetes was 4...
March 22, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28325504/buttressing-of-the-eea-stapler-during-gastrojejunal-anastomosis-decreases-rate-of-bleeding-related-complications-for-laparoscopic-gastric-bypass
#5
Zachary A Ichter, Lindsay Voeller, Homero Rivas, Habib Khoury, Dan Azagury, John M Morton
BACKGROUND: Bariatric surgery is a well-tolerated and effective treatment for severe obesity. Newer surgical techniques and equipment have improved safety standards surrounding bariatric surgery. In particular, buttressing of the staple line in sleeve gastrectomy has decreased rates of clinically significant postoperative bleeding. The present study investigates the effectiveness of buttressing the circular stapled anastomosis during laparoscopic Roux-en-Y gastric bypass (LRYGB). SETTING: Academic, accredited hospital...
January 11, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28323517/differences-in-adolescent-emotion-regulation-and-impulsivity-a-group-comparison-study-of-school-based-recovery-students
#6
Beth S Russell, Anne Thompson Heller, Morica Hutchison
BACKGROUND: Recovery high schools (RHS) vary in organization and operating philosophy, but are designed to support the unique needs of students struggling with substance use disorders (SUD). Previous research on youth risk taking behaviors suggests emotion regulation is a key predictor of outcomes. Specifically, the ability to respond in adaptive rather than maladaptive ways is often associated with challenges of impulsivity, poor distress tolerance, and adolescent substance use. OBJECTIVES: The current study considers data from RHS students in order to answer research questions concerning impulsivity and emotion regulation of youth working to change their risk trajectories in comparison to group of typically developing youth...
March 21, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28318323/sublingual-transdermal-and-intravenous-patient-controlled-analgesia-for-acute-post-operative-pain-systematic-literature-review-and-mixed-treatment-comparison
#7
Pablo Katz, Shweta Takyar, Pamela Palmer, Hiltrud Liedgens
OBJECTIVE: To conduct a systematic literature review (SLR) and quantitative analysis to assess the comparative efficacy and safety of the sufentanil sublingual tablet system (SSTS) against other available patient controlled analgesia (PCA) options for post-operative analgesia. METHODS: An SLR was conducted for studies published between 2004 and 2016. Due to study heterogeneity, subgroup analyses were conducted controlling for differences in imputation methods for missing values, baseline pain severity, and type of surgery...
March 20, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28315268/sigma-1-receptor-antagonists-a-new-class-of-neuromodulatory-analgesics
#8
Cristina Sánchez-Fernández, José Manuel Entrena, José Manuel Baeyens, Enrique José Cobos
The sigma-1 receptor is a unique ligand-operated chaperone present in key areas for pain control, in both the peripheral and central nervous system. Sigma-1 receptors interact with a variety of protein targets to modify their function. These targets include several G-protein-coupled receptors such as the μ-opioid receptor, and ion channels such as the N-methyl-D-aspartate receptor (NMDAR). Sigma-1 antagonists modify the chaperoning activity of sigma-1 receptor by increasing opioid signaling and decreasing NMDAR responses, consequently enhancing opioid antinociception and decreasing the sensory hypersensitivity that characterizes pathological pain conditions...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28306308/application-of-a-resource-theory-for-magic-states-to-fault-tolerant-quantum-computing
#9
Mark Howard, Earl Campbell
Motivated by their necessity for most fault-tolerant quantum computation schemes, we formulate a resource theory for magic states. First, we show that robustness of magic is a well-behaved magic monotone that operationally quantifies the classical simulation overhead for a Gottesman-Knill-type scheme using ancillary magic states. Our framework subsequently finds immediate application in the task of synthesizing non-Clifford gates using magic states. When magic states are interspersed with Clifford gates, Pauli measurements, and stabilizer ancillas-the most general synthesis scenario-then the class of synthesizable unitaries is hard to characterize...
March 3, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28303934/redox-sensing-regulator-rex-regulates-aerobic-metabolism-morphological-differentiation-and-avermectin-production-in-streptomyces-avermitilis
#10
Xingchao Liu, Yaqing Cheng, Mengya Lyu, Ying Wen, Yuan Song, Zhi Chen, Jilun Li
The regulatory role of redox-sensing regulator Rex was investigated in Streptomyces avermitilis. Eleven genes/operons were demonstrated to be directly regulated by Rex; these genes/operons are involved in aerobic metabolism, morphological differentiation, and secondary metabolism. Rex represses transcription of target genes/operons by binding to Rex operator (ROP) sequences in the promoter regions. NADH reduces DNA-binding activity of Rex to target promoters, while NAD(+) competitively binds to Rex and modulates its DNA-binding activity...
March 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28302949/isolated-and-combined-valve-surgery-in-elderly-patients-a-comparison-of-mid-term-results
#11
Fumiya Yoneyama, Chiho Tokunaga, Yoshiharu Enomoto, Kisato Mitomi, Hiroaki Sakamoto, Yuji Hiramatsu
BACKGROUND: This study examined mid-term outcomes of valve surgery in the elderly, and focused on the difference in outcomes between isolated and combined valve surgery. METHODS: From January 2012 to June 2016, 113 consecutive patients aged 75 years and older underwent valve surgery. In all, 60 underwent isolated valve surgery (Group I), and 53 underwent combined valve surgery (Group C) involving the combination of any valve procedures or valve surgery with concurrent other procedure...
March 9, 2017: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28299640/the-role-of-transplanted-visceral-fat-from-the-long-lived-growth-hormone-receptor-knockout-mice-on-insulin-signaling
#12
Mohammed T Bennis, Augusto Schneider, Berta Victoria, Andrew Do, Denise S Wiesenborn, Lina Spinel, Adam Gesing, John J Kopchick, Shadab A Siddiqi, Michal M Masternak
Growth hormone receptor knockout mice (GHRKO) are characterized by high insulin sensitivity and extended lifespan. Interestingly, the secretory activity of visceral fat in GHRKO mice is altered, stimulating whole body insulin sensitivity. In this study, we transplanted normal (N) mice with visceral fat pads from GHRKO or N mice to determine the role of visceral fat on the insulin signaling. We found that the transplant of visceral fat from GHRKO mice to N mice (N-GHRKO) improved whole body insulin sensitivity when comparing with sham-operated mice (N-S) and with mice that received visceral fat from N mice (N-N)...
February 2017: Geroscience
https://www.readbyqxmd.com/read/28299263/clinical-evaluation-of-coverage-of-open-wounds-polyglycolic-acid-sheet-with-fibrin-glue-spray-vs-split-thickness-skin
#13
Yumi Mochizuki, Hirofumi Tomioka, Fumihiko Tushima, Hiroaki Shimamoto, Hideaki Hirai, Yuu Oikawa, Hiroyuki Harada
PURPOSE: This study aimed to evaluate the coverage of oral wounds using either a polyglycolic acid (PGA) sheet or split-thickness skin grafting (STSG). MATERIALS AND METHODS: A total of 119 cases of wound coverage using a PGA sheet and fibrin glue spray as well as 132 cases of wound coverage cases using STSG were reviewed retrospectively. The site of the excision area, perioperative conditions, and postoperative functional problems were evaluated. RESULTS: The PGA group had significantly shorter operation time, earlier start of oral intake, and shorter hospitalization than the STSG group...
July 2016: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28294636/indirect-treatment-comparison-of-two-non-invasive-patient-controlled-analgesia-treatments-for-acute-post-operative-pain-management
#14
Pablo Katz, Shweta Takyar, Pamela Palmer, Hiltrud Liedgens
OBJECTIVES: To evaluate the relative clinical efficacy, safety, and tolerability associated with two non-invasive patient-controlled analgesia (PCA) treatments, sufentanil sublingual tablet system (SSTS) and fentanyl iontophoretic patient-controlled transdermal system (PCTS). These two treatments have recently been approved in the EU for the management of acute moderate-to-severe post-operative pain in adult patients. METHODS: As no head-to-head trials comparing SSTS and PCTS currently exist, indirect treatment comparison (ITC) analyses were conducted to evaluate SSTS or PCTS versus intravenous (IV) morphine PCA...
March 15, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28294441/accuracy-of-pre-operative-real-time-dynamic-transvaginal-ultrasound-sliding-sign-in-prediction-of-pelvic-adhesions-in-women-with-previous-abdominopelvic-surgery-a-prospective-multicenter-double-blinded-study
#15
Amira Ayachi, Rim Bouchahda, Sadok Derouich, Lassaad Mkaouer, Mehdi Kehila, Hassine Abouda, Badis Channoufi, Maha Bouyahia, Marouen Braham, Fethi Zhioua, Haifa Bouchahda, Mechaal Mourali
OBJECTIVE: To highlight the role of the transvaginal ultrasound sliding sign in predicting pelvic adhesions in women with a previous history of abdominopelvic surgery. METHODS: Multicenter prospective, interventional, double blinded study. Patients were examined before the laparoscopy or laparotomy, in gynaecological position, with transvaginal ultrasound (TVU) probe to assess vesico uterine pouch, uterus, ovaries, pouch of Douglas by analysing the gliding between two structures...
March 13, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28293100/adenosine-a2a-receptor-agonist-prevents-cardiac-remodeling-and-dysfunction-in-spontaneously-hypertensive-male-rats-after-myocardial-infarction
#16
Jaqueline S da Silva, Daniele Gabriel-Costa, Roberto T Sudo, Hao Wang, Leanne Groban, Emanuele B Ferraz, José Hamilton M Nascimento, Carlos Alberto M Fraga, Eliezer J Barreiro, Gisele Zapata-Sudo
BACKGROUND: This work evaluated the hypothesis that 3,4-methylenedioxybenzoyl-2-thienylhydrazone (LASSBio-294), an agonist of adenosine A2A receptor, could be beneficial for preventing cardiac dysfunction due to hypertension associated with myocardial infarction (MI). METHODS: Male spontaneously hypertensive rats (SHR) were randomly divided into four groups (six animals per group): sham-operation (SHR-Sham), and myocardial infarction rats (SHR-MI) were treated orally either with vehicle or LASSBio-294 (10 and 20 mg...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28291540/roux-en-y-gastric-bypass-improves-glucose-homeostasis-reduces-oxidative-stress-and-inflammation-in-livers-of-obese-rats-and-in-kupffer-cells-via-an-ampk-dependent-pathway
#17
Yanhua Peng, James Zongyu Li, Min You, Michel M Murr
BACKGROUND: Oxidative stress and inflammation are implicated in the pathogenesis of steatohepatitis. We hypothesize that Roux-en-Y gastric bypass reduces oxidative stress and inflammation in the liver of obese rats via activation of AMPK-α. METHODS: Obese Sprague-Dawley male rats underwent either sham operation or Roux-en-Y gastric bypass. Hepatic TNF-α, NF-κB, IRS-2, PI3 kinase, PKC-ζ, NOX2, and AMPK-α were measured. Mechanistic studies were done in a rat Kupffer cell line (RKC1) that was treated with free fatty acids to mimic lipotoxicity and then transfected with AMPK-α siRNA...
March 10, 2017: Surgery
https://www.readbyqxmd.com/read/28291375/juvenile-idiopathic-arthritis-what-is-the-utility-of-ultrasound
#18
Hershernpal A S Basra, Paul D Humphries
Juvenile Idiopathic Arthritis is a heterogeneous condition and an important cause of acquired disability in children. Evidence supports early treatment to prevent future complications. This relies on prompt diagnosis, achieved by a high index of clinical suspicion and supportive evidence, including the detection of joint and or tendon inflammation. Ultrasound is a readily accessible, well tolerated, safe and accurate modality for assessing joints and the surrounding soft tissues. It can also be used to guide therapy into those joints and tendon sheaths, resistant to systemic treatments...
March 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28289531/critical-analysis-of-ineffective-post-implantation-implantable-cardioverter-defibrillator-testing
#19
Markus Roos, J Christoph Geller, Marc-Alexander Ohlow
AIM: To test of the implantable-cardioverter-defibrillator is done at the time of implantation. We investigate if any testing should be performed. METHODS: All consecutive patients between January 2006 and December 2008 undergoing implantable cardioverter-defibrillator (ICD) implantation/replacement (a total of 634 patients) were included in the retrospective study. RESULTS: Sixteen patients (2.5%) were not tested (9 with LA/LV-thrombus, 7 due to operator's decision)...
February 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28287977/neurostimulation-strategy-for-stress-urinary-incontinence
#20
Xuechen Huang, Kaihui Zheng, Sam Kohan, Petcharat May Denprasert, Limin Liao, Gerald E Loeb
We have developed a percutaneously implantable and wireless microstimulator (NuStim®) to exercise the pelvic floor muscles for treatment of stress urinary incontinence. It produces a wide range of charge-regulated electrical stimulation pulses and trains of pulses using a simple electronic circuit that receives power and timing information from an externally generated RF magnetic field. The complete system was validated in vitro and in vivo in preclinical studies demonstrating that the NuStim can be successfully implanted into an effective, low threshold location and the implant can be operated chronically to produce effective and well-tolerated contractions of skeletal muscle...
March 7, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
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