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https://www.readbyqxmd.com/read/28098529/multidrug-resistant-candida-haemulonii-and-c-auris-tel-aviv-israel
#1
Ronen Ben-Ami, Judith Berman, Ana Novikov, Edna Bash, Yael Shachor-Meyouhas, Shiri Zakin, Yasmin Maor, Jalal Tarabia, Vered Schechner, Amos Adler, Talya Finn
Candida auris and C. haemulonii are closely related, multidrug-resistant emerging fungal pathogens that are not readily distinguishable with phenotypic assays. We studied C. auris and C. haemulonii clinical isolates from 2 hospitals in central Israel. C. auris was isolated in 5 patients with nosocomial bloodstream infection, and C. haemulonii was found as a colonizer of leg wounds at a peripheral vascular disease clinic. Liberal use of topical miconazole and close contact among patients were implicated in C...
February 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28096281/de-freezing-frozen-patient-management
#2
Ayala Kobo-Greenhut, Amin Shnifi, Eran Tal-Or, Racheli Magnezi, Amos Notea, Meir Ruach, Erez Onn, Ayala Cohen, Etti Doveh, Izhar Ben Shlomo
OBJECTIVE: To compare the effectiveness of two methods in encouraging the consideration of a leap from one patient management routine to another: (i) real-time review of the facts by an external medical team (ii) implementation of the 're-thinking-protocol' ('de-Freezing') by both treating and external medical teams. DESIGN: Students accompanied doctors, nurses and patients as non-interrupting observers. When an obvious gap between the expected and actual findings occurred, it was discussed four times: by two teams (treating team, external medical team) in two discussion modes (real-time review, de-Freezing-questionnaire)...
January 16, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28062907/prediction-of-fetal-loss-by-first-trimester-crown-rump-length-in-ivf-pregnancies
#3
Rinat Gabbay-Benziv, Amir Dolev, Ron Bardin, Israel Meizner, Benjamin Fisch, Avi Ben-Haroush
OBJECTIVE: To evaluate the association between small crown-rump length (CRL) and fetal loss ≤22 weeks in IVF pregnancies. METHODS: A retrospective analysis of prospectively collected data at a university-affiliated medical center. All singleton IVF pregnancies within a 5-year period, with a live embryo on first-trimester ultrasound and verified pregnancy outcome were included. Rates of fetal loss ≤22 weeks were compared between pregnancies with a CRL ≤tenth percentile and above the tenth percentile of our population...
January 7, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28060602/patient-violence-toward-psychiatric-health-care-workers-in-israel-as-viewed-through-incident-reports
#4
Tal Drori, Hava Guetta, Merav Ben Natan, Yaakov Polakevich
BACKGROUND: Rates of violence perpetrated by patients toward health care workers are known to be higher in psychiatry than in other fields. Objective standardized reports of violent incidents may clarify this phenomenon. OBJECTIVE: The purpose of this study was to assess the characteristics of patient violence, as evident from objective reports. STUDY DESIGN: In this retrospective chart review study, conducted at a large mental health hospital in Israel between 2013 and 2015, reports of violent incidents perpetrated by people diagnosed with mental health problems against health care workers of the hospital were reviewed...
January 1, 2017: Journal of the American Psychiatric Nurses Association
https://www.readbyqxmd.com/read/28051970/the-effect-of-aging-on-the-ventilatory-response-to-wearing-a-chemical-biological-radiological-and-nuclear-hood-respirator-at-rest-and-during-mild-exercise
#5
Dror Ofir, Yoav Yanir, Mirit Eynan, Ben Aviner, Adi Biram, Michael Mullokandov, Ronen Bar, Yehuda Arieli
BACKGROUND: Structural changes in the human body resulting from aging may affect the response to altered levels of O2 and CO2. An abnormal ventilatory response to a buildup of CO2 in the inspired air due to rebreathing may result in adverse effects, which will impair the individual's ability to function under stress. The purpose of this study was to evaluate the effect of age on the respiratory response to wearing an escape hood at rest and during mild exercise. METHODS: Subjects were seven healthy, young adult males (20-30 years) and seven healthy, middle-aged males (45-65 years)...
January 2017: Military Medicine
https://www.readbyqxmd.com/read/28045486/mimicking-neuroligin-2-functions-in-%C3%AE-cells-by-functionalized-nanoparticles-as-a-novel-approach-for-antidiabetic-therapy
#6
Anna Munder, Liron L Israel, Shirin Kahremany, Rina Ben-Shabat-Binyamini, Charles Zhang, Michal Kolitz-Domb, Olga Viskind, Anna Levine, Hanoch Senderowitz, Steven Chessler, Jean-Paul Lellouche, Arie Gruzman
Both pancreatic β-cell membranes and presynaptic active zones of neurons include in their structures similar protein complexes, which are responsible for mediating the secretion of bioactive molecules. In addition, these membrane-anchored proteins regulate interactions between neurons and guide the formation and maturation of synapses. These proteins include the neuroligins (e.g., NL-2) and their binding partners, the neurexins. The insulin secretion and maturation of β-cells is known to depend on their 3-dimensional (3D) arrangement...
January 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28040286/balloon-dilatation-and-outcome-among-patients-undergoing-trans-femoral-aortic-valve-replacement
#7
Noam Fink, Amit Segev, Ran Kornowski, Ariel Finkelstein, Abid Assali, Zach Rozenbaum, Hana Vaknin-Assa, Amir Halkin, Paul Fefer, Jeremy Ben-Shoshan, Ehud Regev, Maayan Konigstein, Katia Orvin, Victor Guetta, Israel M Barbash
BACKGROUND: Balloon pre-dilatation before transcatheter aortic valve replacement (TAVR) is performed at the discretion of the treating physician. Clinical data assessing the implications of this step on procedural outcomes are limited. METHODS: We conducted a retrospective analysis of 1164 consecutive TAVR patients in the Israeli multicenter TAVR registry (Sheba, Rabin, and Tel Aviv Medical Centers) between the years 2008 and 2014. Patients were divided to those who underwent balloon pre-dilation (n=1026) versus those who did not (n=138)...
December 21, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27993711/late-onset-uretero-vesical-junction-obstruction-following-endoscopic-injection-of-bulking-material-for-the-treatment-of-vesico-ureteral-reflux
#8
David Ben-Meir, Zaher Bahouth, Sarel Halachmi
OBJECTIVE: To characterize patients who develop late obstruction after subureteral injection of bulking agent for the treatment of pediatric vesicoureteral reflux (VUR). METHODS: We retrospectively evaluated the medical records of all patients who underwent endoscopic injection for the correction of VUR during 2008-2015 in 2 centers in Israel: Bnai-Zion Medical Center, Haifa, and Schneider Children's Medical Center, Petah Tikva. Nine patients who developed late-onset obstruction were included in the study, and their data were reviewed and analyzed...
December 16, 2016: Urology
https://www.readbyqxmd.com/read/27992417/mutations-in-the-histone-methyltransferase-gene-kmt2b-cause-complex-early-onset-dystonia
#9
Esther Meyer, Keren J Carss, Julia Rankin, John M E Nichols, Detelina Grozeva, Agnel P Joseph, Niccolo E Mencacci, Apostolos Papandreou, Joanne Ng, Serena Barral, Adeline Ngoh, Hilla Ben-Pazi, Michel A Willemsen, David Arkadir, Angela Barnicoat, Hagai Bergman, Sanjay Bhate, Amber Boys, Niklas Darin, Nicola Foulds, Nicholas Gutowski, Alison Hills, Henry Houlden, Jane A Hurst, Zvi Israel, Margaret Kaminska, Patricia Limousin, Daniel Lumsden, Shane McKee, Shibalik Misra, Shekeeb S Mohammed, Vasiliki Nakou, Joost Nicolai, Magnus Nilsson, Hardev Pall, Kathryn J Peall, Gregory B Peters, Prab Prabhakar, Miriam S Reuter, Patrick Rump, Reeval Segel, Margje Sinnema, Martin Smith, Peter Turnpenny, Susan M White, Dagmar Wieczorek, Sarah Wiethoff, Brian T Wilson, Gidon Winter, Christopher Wragg, Simon Pope, Simon J H Heales, Deborah Morrogh, Alan Pittman, Lucinda J Carr, Belen Perez-Dueñas, Jean-Pierre Lin, Andre Reis, William A Gahl, Camilo Toro, Kailash P Bhatia, Nicholas W Wood, Erik-Jan Kamsteeg, Wui K Chong, Paul Gissen, Maya Topf, Russell C Dale, Jonathan R Chubb, F Lucy Raymond, Manju A Kurian
Histone lysine methylation, mediated by mixed-lineage leukemia (MLL) proteins, is now known to be critical in the regulation of gene expression, genomic stability, cell cycle and nuclear architecture. Despite MLL proteins being postulated as essential for normal development, little is known about the specific functions of the different MLL lysine methyltransferases. Here we report heterozygous variants in the gene KMT2B (also known as MLL4) in 27 unrelated individuals with a complex progressive childhood-onset dystonia, often associated with a typical facial appearance and characteristic brain magnetic resonance imaging findings...
December 19, 2016: Nature Genetics
https://www.readbyqxmd.com/read/27964727/genetic-variation-of-naturally-growing-olive-trees-in-israel-from-abandoned-groves-to-feral-and-wild
#10
Oz Barazani, Alexandra Keren-Keiserman, Erik Westberg, Nir Hanin, Arnon Dag, Giora Ben-Ari, Ori Fragman-Sapir, Yizhar Tugendhaft, Zohar Kerem, Joachim W Kadereit
BACKGROUND: Naturally growing populations of olive trees are found in the Mediterranean garrigue and maquis in Israel. Here, we used the Simple Sequence Repeat (SSR) genetic marker technique to investigate whether these represent wild var. sylvestris. Leaf samples were collected from a total of 205 trees at six sites of naturally growing olive populations in Israel. The genetic analysis included a multi-locus lineage (MLL) analysis, Rousset's genetic distances, Fst values, private alleles, other diversity values and a Structure analysis...
December 13, 2016: BMC Plant Biology
https://www.readbyqxmd.com/read/27939127/cocontribution-of-rotavirus-and-pneumococcal-conjugate-vaccines-to-the-reduction-of-pediatric-hospital-visits-in-young-children
#11
Shalom Ben-Shimol, Noga Givon-Lavi, David Greenberg, Ron Dagan
OBJECTIVE: To assess rotavirus vaccine and pneumococcal conjugate vaccines (PCVs) cumulative impact on the pediatric emergency department visits and hospitalization rates in children <2 years of age in southern Israel between April 2006 and March 2014. STUDY DESIGN: This prospective, population-based observational study calculated the rates of rotavirus gastroenteritis (RVGE), non-RVGE, community-acquired alveolar pneumonia (CAAP), nonalveolar lower respiratory tract infection, and all-cause hospital visits...
December 8, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27879969/factors-associated-with-choice-of-approach-for-group-b-streptococcus-screening
#12
H Sefty, A Klivitsky, M Bromberg, R Dichtiar, M Ben Ami, T Shohat, A Glatman-Freedman
BACKGROUND: The crude rate of early-onset Group B streptococcus disease (EOGBS) in Israel has been consistently under 0.5 for 1000 live births for the past 8 years. The Israeli Ministry of Health has adapted the risk factor based approach for preventing EOGBS and universal bacteriological screening for GBS is not recommended. In spite of this policy, there are indications that many pregnant women in Israel undergo bacteriological screening for GBS. The objective of this study is to assess the rate and characteristics of pregnant women who undergo screening for group B streptococcus (GBS) colonization in Israel...
2016: Israel Journal of Health Policy Research
https://www.readbyqxmd.com/read/27876594/successful-control-of-a-large-outbreak-of-hiv-infection-associated-with-injection-of-cathinone-derivatives-in-tel-aviv-israel
#13
Eugene Katchman, Ronen Ben-Ami, Michal Savyon, Daniel Chemtob, Boaz Avidor, Asaf Wasserman, Irena Zeldis, Shirley Girshengorn, Ziva Amitai, Rivka Sheffer, Dan Turner
OBJECTIVES: Outbreaks of HIV infection have been linked to injectable drug abuse, but specific triggers often remain obscure. We report on an outbreak of primary HIV infection among people who inject drugs (PWID) in Tel Aviv, associated with a local shift in drug-use practices. METHODS: A cluster of primary HIV infection cases in PWID was detected in May 2012. Retrospective and prospective multi-hospital case finding was initiated. PWID were interviewed and risk factors for primary HIV infection were identified...
November 19, 2016: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/27864577/diagnosing-necrotic-meningioma-a-distinctive-imaging-pattern-in-diffusion-mri-and-mr-spectroscopy
#14
Gal Ben-Arie, Yonatan Serlin, Sebastian Ivens, Mony Benifla, Emanuela Cagnano, Israel Melamed, Vladimir Merkin, Ilan Shelef
The differential diagnosis of necrotic meningiomas includes brain abscess and malignant neoplasms. We report and discuss hereby the work-up of two patients diagnosed with necrotic meningioma using diffusion-weighted imaging, magnetic resonance spectroscopy, resective surgery, and histopathology. The purpose of the present article is to add to the scant literature on the use of advanced imaging modalities in the routine investigation of brain lesions and their utility in arriving at the final diagnosis.
November 18, 2016: Neuroradiology Journal
https://www.readbyqxmd.com/read/27844150/c-shaped-canals-prevalence-and-root-canal-configuration-by-cone-beam-computed-tomography-evaluation-in-first-and-second-mandibular-molars-a-cross-sectional-study
#15
Avi Shemesh, Avi Levin, Vered Katzenell, Joe Ben Itzhak, Oleg Levinson, Zini Avraham, Michael Solomonov
OBJECTIVES: C-shaped root canal configuration is an unusual root canal morphology and one of the most often anatomical variations in root canal systems of second mandibular molars. The purpose of this study was to assess the prevalence, symmetry and configuration of C-shaped canals in first and second mandibular molars in an Israeli population using cone beam computed tomography (CBCT). MATERIALS AND METHODS: One thousand twenty Israel patients' CBCT scans were screened and evaluated...
November 14, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27826413/parental-regret-regarding-children-s-vaccines-the-correlation-between-anticipated-regret-altruism-coping-strategies-and-attitudes-toward-vaccines
#16
Yaira Hamama-Raz, Eyal Ginossar-David, Menachem Ben-Ezra
BACKGROUND: Parental hesitancy for recommended childhood vaccines is a growing public health concern influenced by various factors. This study aimed to explore regret regarding parental decisions to vaccinate their children via possible correlations between anticipated regret, altruism, coping strategies, and parents' attitudes toward the vaccination of their children. METHODS: The study was conducted during 2014 in Israel. Data were collected via snowballing methodology (i...
2016: Israel Journal of Health Policy Research
https://www.readbyqxmd.com/read/27821367/a-blast-from-the-past-civilians-immediate-psychological-reactions-and-associative-memory-of-prior-events-following-exploding-bus-in-israel
#17
Menachem Ben-Ezra, Shani Pitcho-Prelorentzos, Michal Mahat-Shamir
This study examined the association between self-report associative memories of prior traumatic events and psychological distress up to 48h after a terror attack. To date, the number of studies that examined this association is very small and most were conducted weeks or even months post event. For this purpose, we examined the association between self-report associative memories of prior traumatic events beyond factors such as previous exposure to trauma, political shift and sense of safety. The results showed that self-report associative memories of prior traumatic events were significantly associated with psychological distress...
December 30, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27817915/evicel-versus-tisseel-versus-sutures-for-attaching-conjunctival-autograft-in-pterygium-surgery-a-prospective-comparative-clinical-study
#18
Ofira Zloto, Eran Greenbaum, Ido Didi Fabian, Guy J Ben Simon
PURPOSE: To evaluate the outcome of pterygium surgery with conjunctival autograft using Vicryl sutures (Ethicon, NJ), Evicel fibrin glue (Omrix Biopharmaceuticals Ltd, Ramat-Gan, Israel), or Tisseel fibrin glue (Baxter Corp., Deerfield, IL). DESIGN: Prospective, randomized study. PARTICIPANTS: Eighty-nine adult patients with primary pterygium. METHODS: Patients undergoing pterygium surgery with conjunctival autografting were randomized into groups receiving 10-0 Vicryl sutures, Evicel fibrin glue, or Tisseel fibrin glue...
January 2017: Ophthalmology
https://www.readbyqxmd.com/read/27794165/a-novel-transcutaneous-non-focused-ultrasound-energy-delivering-device-is-able-to-induce-subcutaneous-adipose-tissue-destruction-in-an-animal-model
#19
Assi Levi, Dan Ben Amitai, Moshe Lapidoth
BACKGROUND AND OBJECTIVES: The understanding that adipocytes are greatly influenced by thermal changes combined with the advancement of non-invasive ultrasound technologies have led to the application of ultrasound as an energy source to induce thermal fat destruction. While application of high intensity focused, ultrasound energy have been widely explored, there is far less information regarding the effects of non-focused ultrasound on adipose tissue. The purpose of this study was to characterize the effects of a novel transcutaneous, multi-elements, non-focused ultrasound energy regimen in an animal model, as a proof-of-concept of its potential to treat non-invasive subcutaneous benign tumors...
October 29, 2016: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/27787222/cutaneous-leishmaniasis-caused-by-leishmania-infantum-in-southern-israel
#20
Shalom Ben-Shimol, Orli Sagi, Amir Horev, Yonat Shemer Avni, Mati Ziv, Klaris Riesenberg
Cutaneous leishmaniasis (CL) caused by Leishmania major is common in southern Israel, while Leishmania infantum (sub-strain of L. donovani, causing zoonotic visceral leishmaniasis) infections were rarely reported in Israel and only in other regions. We report the first case of L. infantum infection in southern Israel, presented atypically as CL in an immunosuppressed 47-year old male. The patient was treated with liposomal amphotericin-B and recovered, without extra-cutaneous complications. Diagnosis of L. infantum CL was confirmed by microscopic identification of amastigotes in Gimsa-stained smear of skin lesion, positive blood serology and a positive polymerase chain reaction (PCR) amplification of the internal transcribed spacer 1 genes (ITS1) and restriction fragment length polymorphism (ITS1 PCR-RFLP)...
December 1, 2016: Acta Parasitologica
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