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https://www.readbyqxmd.com/read/28634260/did-the-suicide-barrier-work-after-all-revisiting-the-bloor-viaduct-natural-experiment-and-its-impact-on-suicide-rates-in-toronto
#1
Mark Sinyor, Ayal Schaffer, Donald A Redelmeier, Alex Kiss, Yasunori Nishikawa, Amy H Cheung, Anthony J Levitt, Jane Pirkis
OBJECTIVE: This research aims to determine the long-term impact of the Bloor Street Viaduct suicide barrier on rates of suicide in Toronto and whether media reporting had any impact on suicide rates. DESIGN: Natural experiment. SETTING: City of Toronto, Canada; records at the chief coroner's office of Ontario 1993-2003 (11 years before the barrier) and 2004-2014 (11 years after the barrier). PARTICIPANTS: 5403 people who died by suicide in the city of Toronto...
June 19, 2017: BMJ Open
https://www.readbyqxmd.com/read/28629863/the-unfolding-mechanism-of-monomeric-mutant-sod1-by-simulated-force-spectroscopy
#2
Mona Habibi, Jörg Rottler, Steven S Plotkin
Mechanical unfolding of mutated apo, disulfide-reduced, monomeric superoxide dismutase 1 protein (SOD1) has been simulated via force spectroscopy techniques, using both an all-atom (AA), explicit solvent model and a coarse-grained heavy-atom Gō (HA-Gō) model. The HA-Gō model was implemented at two different pulling speeds for comparison. The most-common sequence of unfolding in the AA model agrees well with the most-common unfolding sequence of the HA-Gō model, when the same normalized pulling rate was used...
June 16, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28612306/bone-density-and-body-composition-in-newly-licenced-professional-jockeys
#3
K A Jackson, M T Sanchez-Santos, A L MacKinnon, A Turner, K Kuznik, S Ellis, C Box, J Hill, M K Javaid, C Cooper, N K Arden, J L Newton
The primary objective is the description of bone mineral density (BMD) and body composition in newly licensed jockeys. One in three male, flat jockeys has a very low bone mineral density. Further research is needed to assess the short-term risk of fractures and long-term health implications of these findings. INTRODUCTION: Describe bone mineral density (BMD) and body composition in entry-level male and female, flat and jump jockeys in Great Britain. METHODS: Data was collected on jockeys applying for a professional jockey license between 2013 and 2015...
June 13, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28595399/modeling-the-nonlinear-dielectric-response-of-glass-formers
#4
U Buchenau
The recently developed pragmatical model of asymmetric double-well potentials with a finite lifetime is applied to nonlinear dielectric data in polar undercooled liquids. The viscous effects from the finite lifetime provide a crossover from the cooperative jumps of many molecules at short times to the motion of statistically independent molecules at long times. The model allows us to determine the size of cooperatively rearranging regions from nonlinear ω-data and throws new light on a known inconsistency between nonlinear ω and 3ω-signals for glycerol and propylene carbonate...
June 7, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28592487/electrostatic-control-of-dna-intersegmental-translocation-by-the-ets-transcription-factor-etv6
#5
Tam Vo, Shuo Wang, Gregory M K Poon, W David Wilson
To find their DNA target sites in complex solution environments containing excess heterogeneous DNA, sequence-specific DNA-binding proteins execute various translocation mechanisms known collectively as facilitated diffusion. For proteins harboring a single DNA contact surface, long-range translocation occurs by jumping between widely spaced DNA segments. We have configured biosensor-based surface plasmon resonance to directly measure the affinity and kinetics of this intersegmental jumping by the ETS-family transcription factor ETS variant 6 (ETV6)...
June 7, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28560342/how-birds-direct-impulse-to-minimize-the-energetic-cost-of-foraging-flight
#6
Diana D Chin, David Lentink
Birds frequently hop and fly between tree branches to forage. To determine the mechanical energy trade-offs of their bimodal locomotion, we rewarded four Pacific parrotlets with a seed for flying voluntarily between instrumented perches inside a new aerodynamic force platform. By integrating direct measurements of both leg and wing forces with kinematics in a bimodal long jump and flight model, we discovered that parrotlets direct their leg impulse to minimize the mechanical energy needed to forage over different distances and inclinations...
May 2017: Science Advances
https://www.readbyqxmd.com/read/28542160/the-phylogeography-of-myotis-bat-associated-rabies-viruses-across-canada
#7
Susan Nadin-Davis, Noor Alnabelseya, M Kimberly Knowles
As rabies in carnivores is increasingly controlled throughout much of the Americas, bats are emerging as a significant source of rabies virus infection of humans and domestic animals. Knowledge of the bat species that maintain rabies is a crucial first step in reducing this public health problem. In North America, several bat species are known to be rabies virus reservoirs but the role of bats of the Myotis genus has been unclear due to the scarcity of laboratory confirmed cases and the challenges encountered in species identification of poorly preserved diagnostic submissions by morphological traits alone...
May 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28541507/current-management-and-clinical-outcomes-for-catheter-ablation-of-atrioventricular-nodal-re-entrant-tachycardia
#8
Jonathan Chrispin, Satish Misra, Joseph E Marine, John Rickard, Andreas Barth, Aravindan Kolandaivelu, Hiroshi Ashikaga, Harikrishna Tandri, David D Spragg, Jane Crosson, Ronald D Berger, Gordon Tomaselli, Hugh Calkins, Sunil K Sinha
Aims: Historical studies of ablation of atrioventricular nodal re-entrant tachycardia (AVNRT) have shown high long-term success rates and low complication rates. The potential impact of several recent practice trends has not been described. This study aims to characterize recent clinical practice trends in AVNRT ablation and their associated success rates and complications. Methods and results: Patients undergoing initial ablation of AVNRT between 1 July 2005 and 30 June 2015 were included in this study...
May 24, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28527741/reeling-in-the-damages-harmful-algal-blooms-impact-on-lake-erie-s-recreational-fishing-industry
#9
David Wolf, Will Georgic, H Allen Klaiber
Lake Erie is one of the most valuable natural resources in the United States, providing billions of dollars in benefits each year to recreationalists, homeowners and local governments. The ecosystem services provided by Lake Erie, however, are under threat due to harmful algal blooms. This paper provides recreational damage estimates using spatially and temporally varying algae measures and monthly fishing permit sales collected between 2011 and 2014. Results indicate that fishing license sales drop between 10% and 13% when algal conditions surpass the World Health's Organization's moderate health risk advisory threshold of 20,000 cyanobacteria cells/mL...
September 1, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28526219/cardiorespiratory-fitness-and-muscular-strength-as-mediators-of-the-influence-of-fatness-on-academic-achievement
#10
Antonio García-Hermoso, Irene Esteban-Cornejo, Jordi Olloquequi, Robinson Ramírez-Vélez
OBJECTIVE: To examine the combined association of fatness and physical fitness components (cardiorespiratory fitness [CRF] and muscular strength) with academic achievement, and to determine whether CRF and muscular strength are mediators of the association between fatness and academic achievement in a nationally representative sample of adolescents from Chile. STUDY DESIGN: Data were obtained for a sample of 36 870 adolescents (mean age, 13.8 years; 55.2% boys) from the Chilean System for the Assessment of Educational Quality test for eighth grade in 2011, 2013, and 2014...
May 16, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28522227/promoting-motor-skills-in-low-income-ethnic-children-the-physical-activity-in-linguistically-diverse-communities-paldc-nonrandomized-trial
#11
Anthony D Okely, Louise L Hardy, Marijka Batterham, Phillip Pearson, Kim McKeen, Lauren Puglisi
OBJECTIVES: This study reports the long-term effects of a professional learning program for classroom teachers on fundamental motor skill (FMS) proficiency of primary school students from ethnically diverse backgrounds. DESIGN: A cluster non-randomized trial using a nested cross-sectional design. METHODS: The study was conducted in 8 primary schools located in disadvantaged and culturally diverse areas in Sydney, Australia. The intervention used an action learning framework, with each school developing and implementing an action plan for enhancing the teaching of FMS in their school...
May 8, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28521272/impact-of-prematurity-on-exercise-capacity-and-agility-of-children-and-youth-aged-8-to-18
#12
Tatjana Robič Pikel, Gregor Starc, Janko Strel, Marjeta Kovač, Janez Babnik, Petra Golja
BACKGROUND: Preterm (PT) birth and low birth mass (LBW) can impair growth and development of children and may therefore affect their physical performance up to adulthood. AIMS: Our aim was to evaluate long-term consequences of prematurity, especially (an)aerobic exercise capacity and agility up to adulthood, by comparing premature and full-term (FT) individuals. STUDY DESIGN, SUBJECTS: From 474 subjects born in 1987, who were enrolled into a longitudinal study, 396 (178 PT and 218 FT (with 127 of them LBW)) were followed-up into their early adulthood...
July 2017: Early Human Development
https://www.readbyqxmd.com/read/28498226/anterior-cruciate-ligament-injury-return-to-play-function-and-long-term-considerations
#13
Fernando Sepúlveda, Luis Sánchez, Eduardo Amy, William Micheo
Anterior cruciate ligament tears are common and affect young individuals who participate in jumping and pivoting sports. After injury many individuals undergo ligament reconstruction (ACLR) but do not return to play, suffer recurrent injury and osteoarthritis. Outcome studies show that after ACLR, 81% of individuals return to sports, 65% return to their preinjury level and 55% return to competitive sports. Systematic reviews place the risk of ipsilateral retears at 5.8% and contralateral injuries at 11.8%, with recent reports of over 20% failure rate...
May 2017: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/28494261/relationship-between-physical-performance-and-self-reported-function-in-healthy-individuals-across-the-lifespan
#14
Jennifer N Baldwin, Marnee J McKay, Claire E Hiller, Niamh Moloney, Elizabeth J Nightingale, Joshua Burns
BACKGROUND: Functional outcome measures in clinical trials of musculoskeletal conditions need to be meaningful to individuals. OBJECTIVES: To investigate the relationship between physical performance and self/proxy-reported function in 1000 healthy children and adults. DESIGN: Cross-sectional observational study (1000 Norms Project). METHODS: One thousand males and females aged 3-101 years, healthy by self-report and without major physical disability, were recruited...
May 2, 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28489955/isometric-and-dynamic-strength-and-neuromuscular-attributes-as-predictors-of-vertical-jump-performance-in-11%C3%A2-13-year-old-male-athletes
#15
Brandon John McKinlay, Phillip J Wallace, Raffy Dotan, Devon Long, Craig Tokuno, David A Gabriel, Bareket Falk
In explosive contractions, neural activation is a major factor in determining the rate of torque development, while the latter is an important determinant of jump performance. However, the contribution of neuromuscular activation and rate of torque development to jump performance in children and youth is unclear. PURPOSE: To examine the relationships between the rate of neuromuscular activation, peak torque, rate of torque development, and jump performance in young male athletes. METHODS: Forty-one 12...
May 10, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28484752/doped-%C3%AE-bismuth-oxides-to-investigate-oxygen-ion-transport-as-a-metric-for-condensed-phase-thermite-ignition
#16
Xizheng Wang, Wenbo Zhou, Jeffery B DeLisio, Garth C Egan, Michael R Zachariah
Nanothermites offer high energy density and high burn rates, but are mechanistically only now being understood. One question of interest is how initiation occurs and how the ignition temperature is related to microscopic controlling parameters. In this study, we explored the potential role of oxygen ion transport in Bi2O3 as a controlling mechanism for condensed phase ignition reaction. Seven different doped δ-Bi2O3 were synthesized by aerosol spray pyrolysis. The ignition temperatures of Al/doped Bi2O3, C/doped Bi2O3 and Ta/doped Bi2O3 were measured by temperature-jump/time-of-flight mass spectrometer coupled with a high-speed camera respectively...
May 24, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28479421/outcomes-of-isolated-tibial-endovascular-intervention-for-rest-pain-in-patients-on-dialysis
#17
Hallie E Baer-Bositis, Taylor D Hicks, Georges M Haidar, Matthew J Sideman, Lori L Pounds, Mark G Davies
BACKGROUND: Tibial interventions for critical limb ischemia are frequent in patients with end-stage renal disease (ESRD) presenting with critical ischemia. The aim of this study was to examine impact of ESRD on the patient-centered outcomes following tibial endovascular Intervention for rest pain. METHODS: A database of patients undergoing lower extremity endovascular interventions between 2006 and 2016 was retrospectively queried. Patients with rest pain (Rutherford 4) were identified...
May 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28475552/analysis-of-the-effect-size-of-overweight-in-muscular-strength-tests-among-adolescents-reference-values-according-to-sex-age-and-bmi
#18
Emilio J Martínez-López, Manuel De La Torre-Cruz, Sara Suarez-Manzano, Alberto Ruiz-Ariza
The aim of this paper is to quantify the effect size of overweight on the results of muscular strength tests in adolescents and to report percentile tables based on sex, age and BMI. The study hypothesized that the effect size obtained from the difference between normal-weight and overweight youth would be greater than the differences between sexes within the same age group. A total of 11044 Spanish adolescents (48.5% girls) aged 14.39 ± 1.21 years (range: 12-16 years) from 42 secondary schools participated in the research...
April 25, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28473687/poor-physical-performance-is-associated-with-obesity-among-university-students-in-china
#19
Tianhua Du, Ergang Zhu, Suhua Jiao
BACKGROUND The aim of this study was to explore the relationship between physical performance and BMI (body mass index) of university students in China. MATERIAL AND METHODS We conducted a cross-sectional study evaluating the physical performance and BMI of university students. BMI was calculated based on height and weight. Overweight and obesity were defined by the Working Group on Obesity references in China. RESULTS A total of 2313 participants (978 males and 1335 females) were recruited in our study. The mean value of the 50-meter dash and standing long jump in male students was higher than in female students (P<0...
May 5, 2017: Medical Science Monitor Basic Research
https://www.readbyqxmd.com/read/28468924/jumping-without-slipping-leafhoppers-hemiptera-cicadellidae-possess-special-tarsal-structures-for-jumping-from-smooth-surfaces
#20
Christofer J Clemente, Hanns Hagen Goetzke, James M R Bullock, Gregory P Sutton, Malcolm Burrows, Walter Federle
Many hemipteran bugs can jump explosively from plant substrates, which can be very smooth. We therefore analysed the jumping performance of froghoppers (Philaenus spumarius, Aphrophoridae) and leafhoppers (Aphrodes bicinctus/makarovi, Cicadellidae) taking off from smooth (glass) and rough (sandpaper, 30 µm asperity size) surfaces. On glass, the propulsive hind legs of Philaenus froghoppers slipped, resulting in uncontrolled jumps with a fast forward spin, a steeper angle and only a quarter of the velocity compared with jumps from rough surfaces...
May 2017: Journal of the Royal Society, Interface
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