phisiology

BACKGROUND: In concurrence of our recent findings of the elevation of QT dispersion (QTd) in the group of pregnant women, mathematical approaches were developed aimed to give possible geometrical explanation whether the observed changes result from the rotation or from the changed position of the heart. METHODS AND RESULTS: Mathematical model of the cardiac electrical field approximated as a time variable dipole in a homogenous spatial conductor was developed. From the experimental vectocardiographic records, representing time course of the cardiac dipole, body surface potential maps were calculated on the basis of the model...

New frontiers have been opened lately in the understanding of the patho-phisiology of preeclampsia thus giving new directions in the process of therapy of this condition. Oxidative stress is a condition characterized by peroxidants predominating over antioxidants. Numerous intensive studies are carried out to reveal the role of oxidative stress in the pathogenesis of preeclampsia.

INTRODUCTION: Among the differents techniques for motor unit number estimation (MUNE) there is the statistical one (Poisson), in which the activation of motor units is carried out by electrical stimulation and the estimation performed by means of a statistical analysis based on the Poisson s distribution. OBJECTIVES: The study was undertaken in order to realize an approximation to the MUNE Poisson technique showing a coprehensible view of its methodology and also to obtain normal results in the extensor digitorum brevis muscle (EDB) from a healthy population...

The phorbol esters, such as phorbol 12- myristate 13-acetate (PMA), are known to be powerful tumor promoters and activators of protein kinase C (PKC). First discovered by Nishizuka et al., PKC is a phospholipid- and calcium-dependent serine/threonine kinase, phisiologically activated by 1,2-diacyl-sn-glycerol (DAG). PKC is also known to be an important target for other structurally diverse tumor promoters such as ingenols, teleocidins, and aplysiatoxins. Structure-activity analyses of a variety of analogs of DAG and these tumor promoters have been carried out...

The historical aspects of phisiology are briefly outlined. The main factors that promote the prevalence of tuberculosis are characterized. The present-day tuberculosis epidemiological situation makes one to correct antituberculous measures and with the use of new investigations and developments to improve the identification of patients with tuberculosis, primarily those with contagious types of the disease, to introduce the currently available short-term regimens of 2-stage drug therapy, to design novel agents and depot formulations of the well known ones...

In this paper the main question is about the health complete interpretation. It is an epistemological discussion. It starts with the obstacles in the comprehension from several sciences (i.e. phisiology, epidemiology, and sociology) about the health as a social and collective problem. The point is how to do the research and the conceptual interpretation. Finally, the authors explain theirs point of view: the most important is the nature and specificity of the objet health. Not view disciplinary. They show a model to understand the analysis of the health from the social sciences perspective...

Authors present their adopted measures, in the different clinical stages of endotoxic shock with a phisiological approach, paying special attention to those secondary to meningococcal infections.

The analysis of the common bundle and of the ventrical filtered electrograms has incrased our knowledge of the intraventricular conduction following the simulation of the PVS as well as the different types or reciprocating that can be produced by premature beats. 2. The positive QRS complexes in V1 produced from PVD by St2 can be explained as a greater degree of incomplete recuperation of the right ventricular wall than in the interventricular septum. In contrast with what happened in the basal beats, where the front took longer to reach the TSVD than the VI...

The results of double blind clinical, phisiological, biochemical immunological and virological studies carried out in 460 normal volunteers gave sufficiently objective evaluation of safety and antiinfluenza activity of bonaphthone. The new antiviral drug is recommended for wide epidemiological trials. In epidemiological, coded and strictly controlled experiment during influenza A/England epidemic in 1973 involving 1393 persons the prophylactic effectiveness of bonaphthone was established (the index of effectiveness 2...

The electric stimulation of sensitive peripheric fibres has been used with good results in the control of pain. It is belived that the modern theory of pain phisiology offers scientific basis to explain its action mechanism. This method was applied to twenty-one patients suffering from trigeminalgia, being continually stimulated during thirty minutes with variable voltages, according to the affected region. As a result, it was obtained the immediate relief of pain for periods of time varying from six and forty-eight hours...

The AA. describe a method of gradual occlusion of the portal vein in the rat to induce a hepatic encephalopaty. This method allows to realise a condition of hepatic ischemia and a portal hypertensive state accompanied by spontaneous portal-systemic shunts. These two factors produce a hepatic encephalopaty like in cirrhotic state or in patients after portal systemic anastomosis. A part from similar behavior at the beginning of the encephalopaty it is possible to define two classes of animals: one showing a slow recovery and one showing a transient and slight improvement followed at the end by the death of the animal...

The velocity of intestinal transit was studied in 24 healthy volunteers using as a marker a small rubber bag which contained 7 to 10 microcuries of NaI 131. The bag was ingested and its passage along the digestive tract followed over the abdominal surface with the help of a collimated scintillation counter connected to an automatic counting system. The time elapsing since ingestion of the bag until its expulsion with feces was taken as the intestinal transit time. In a normal subject, transit of the bag was compared with the one of plastic radioopaque pellets whose passage along the intestine can be followed radiologically, and which at present are considered the best existent marker to measure velocity of intestinal transit...

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