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https://www.readbyqxmd.com/read/28087566/application-of-whole-exome-sequencing-in-the-clinical-diagnosis-and-management-of-inherited-cardiovascular-diseases-in-adults
#1
Sara B Seidelmann, Emily Smith, Lakshman Subrahmanyan, Daniel Dykas, Maen D Abou Ziki, Bani Azari, Fady Hannah-Shmouni, Yuexin Jiang, Joseph G Akar, Mark Marieb, Daniel Jacoby, Allen E Bale, Richard P Lifton, Arya Mani
BACKGROUND: With the advent of high throughput sequencing, the identification of genetic causes of cardiovascular disease (CVD) has become an integral part of medical diagnosis and management and at the forefront of personalized medicine in this field. The use of whole exome sequencing for clinical diagnosis, risk stratification, and management of inherited CVD has not been previously evaluated. METHODS AND RESULTS: We analyzed the results of whole exome sequencing in first 200 adult patients with inherited CVD, who underwent genetic testing at the Yale Program for Cardiovascular Genetics...
February 2017: Circulation. Cardiovascular Genetics
https://www.readbyqxmd.com/read/28076978/abortion-services-at-hospitals-in-istanbul
#2
Mary Lou O'Neil
OBJECTIVE: Despite the existence of a liberal law on abortion in Turkey, there is growing evidence that actually securing an abortion in Istanbul may prove difficult. This study aimed to determine whether or not state hospitals and private hospitals that accept state health insurance in Istanbul are providing abortion services and for what indications. METHOD: Between October and December 2015, a mystery patient telephone survey of 154 hospitals, 43 public and 111 private, in Istanbul was conducted...
January 12, 2017: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/28073735/patient-information-websites-about-medically-induced-second-trimester-abortions-a-descriptive-study-of-quality-suitability-and-issues
#3
Tommy Carlsson, Ove Axelsson
BACKGROUND: Patients undergoing medically induced second-trimester abortions feel insufficiently informed and use the Web for supplemental information. However, it is still unclear how people who have experience with pregnancy termination appraise the quality of patient information websites about medically induced second-trimester abortions, whether they consider the websites suitable for patients, and what issues they experience with the websites. OBJECTIVE: Our objective was to investigate the quality of, suitability of, and issues with patient information websites about medically induced second-trimester abortions and potential differences between websites affiliated with the health care system and private organizations...
January 10, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28063830/implications-of-dispensing-self-administered-hormonal-contraceptives-in-a-one-year-supply-a-california-case-study
#4
Sara B McMenamin, Shana Alex Charles, Nadia Tabatabaeepour, Erin Shigekawa, Garen Corbett
On September 23, 2016, California became the 6th state to pass legislation requiring health plans and insurers to cover a 12-month supply of FDA-approved self-administered hormonal contraceptives such as contraceptive pills, patches, and vaginal rings. This legislation is estimated to result in 47% of current contraceptive pill, patch, and ring users receiving a 12-month supply dispensed at one time. This shift in dispensing patterns was estimated to result in a reduction of 15,000 unintended pregnancies; 2000 fewer miscarriages; and 7000 fewer abortions in California decreasing total net health care expenditures by 0...
January 4, 2017: Contraception
https://www.readbyqxmd.com/read/28060817/high-levels-of-post-abortion-complication-in-a-setting-where-abortion-service-is-not-legalized
#5
Tadele Melese, Dereje Habte, Billy M Tsima, Keitshokile Dintle Mogobe, Kesegofetse Chabaesele, Goabaone Rankgoane, Tshiamo R Keakabetse, Mabole Masweu, Mosidi Mokotedi, Mpho Motana, Badani Moreri-Ntshabele
BACKGROUND: Maternal mortality due to abortion complications stands among the three leading causes of maternal death in Botswana where there is a restrictive abortion law. This study aimed at assessing the patterns and determinants of post-abortion complications. METHODS: A retrospective institution based cross-sectional study was conducted at four hospitals from January to August 2014. Data were extracted from patients' records with regards to their socio-demographic variables, abortion complications and length of hospital stay...
2017: PloS One
https://www.readbyqxmd.com/read/28024680/politics-policies-pronatalism-and-practice-availability-and-accessibility-of-abortion-and-reproductive-health-services-in-turkey
#6
Katrina A MacFarlane, Mary Lou O'Neil, Deniz Tekdemir, Elvin Çetin, Barış Bilgen, Angel M Foster
Turkey has maintained liberal contraception and abortion policies since the 1980s. In 2012, the government proposed to restrict abortion; a bill limiting abortion was later drafted but never passed into law. Since the proposed restriction, women have reported difficulty accessing abortion services across Turkey. We aimed to better understand the current availability of abortion and reproductive health services in Istanbul and explore whether access to services has changed since 2012. In 2015, we completed 14 in-depth interviews with women and 11 semi-structured interviews with key informants...
November 2016: Reproductive Health Matters
https://www.readbyqxmd.com/read/28017280/nutritional-beliefs-and-practices-among-diabetic-pregnant-mothers-in-a-tertiary-care-hospital-in-bangladesh
#7
Ummy Salma Munni, Sharmin Hossain, Kazi Rumana Ahmed
BACKGROUND & AIM: Pregnant mothers with diabetes, especially in developing countries, are particularly prone to suffer from dietary imbalances due to superstitions and irrational beliefs and practices. The study aimed to explore the existing beliefs and practices related to food intake among Bangladeshi diabetic pregnant mothers. MATERIAL & METHODS: A cross-sectional study was conducted among 200 diabetic pregnant mothers (age in yrs, M±SD, 30±4), selected purposively from outpatient department of Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine & Metabolic Disorders...
December 13, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/27992701/mandated-state-waiting-periods-linked-to-delays-in-obtaining-abortion-care
#8
(no author information available yet)
No abstract text is available yet for this article.
December 2016: Perspectives on Sexual and Reproductive Health
https://www.readbyqxmd.com/read/27960606/sociodemographic-sexual-reproductive-and-relationship-characteristics-of-adolescents-having-an-abortion-in-portugal-a-homogeneous-or-a-heterogeneous-group
#9
Joana Pereira, Raquel Pires, Anabela Araújo Pedrosa, Lisa Vicente, Teresa Bombas, Maria Cristina Canavarro
OBJECTIVES: The aims of the study were to describe the sociodemographic, sexual, reproductive and relational characteristics of adolescents having an abortion in Portugal and to explore the differences between three adolescent age groups. METHODS: We recruited a nationally representative sample of 224 adolescents (<16 years, n =  18; 16-17 years, n =  103; 18-19 years, n =  103) who had an abortion. Data were collected from 16 health care services that provide abortion...
December 14, 2016: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/27940526/conscience-and-agent-integrity-a-defence-of-conscience-based-exemptions-in-the-health-care-context
#10
Mary Neal, Sara Fovargue
The issue of conscientious refusal by health care practitioners continues to attract attention from academics, and was the subject of a recent UK Supreme Court decision. Activism aimed at changing abortion law and the decision to devolve governance of abortion law to the Scottish Parliament both raise the prospect of altered provision for conscience in domestic law. In this article, building on earlier work, we argue that conscience is fundamentally connected to moral integrity and essential to the proper functioning of moral agency...
December 10, 2016: Medical Law Review
https://www.readbyqxmd.com/read/27938866/equitable-abortion-care-a-challenge-for-health-care-providers-experiences-from-abortion-care-encounters-with-immigrant-women-in-stockholm-sweden
#11
Elin C Larsson, Sarah Fried, Birgitta Essén, Marie Klingberg-Allvin
OBJECTIVE: To explore health care providers' experiences of providing care to immigrant women seeking abortion care. METHODS: A qualitative study including interviews with ten midwives and three medical doctors at four abortion clinics in the Stockholm area. Interviews were analysed using thematic analysis. RESULTS: Initially, health care providers were reluctant to make statements concerning the specific needs among immigrant women. Yet, the health care providers sometimes found it challenging to deal with the specific needs among immigrant, mostly non-European, women...
December 2016: Sexual & Reproductive Healthcare: Official Journal of the Swedish Association of Midwives
https://www.readbyqxmd.com/read/27925122/-abortion-and-stigma-an-analysis-of-the-scientific-literature-on-the-theme
#12
Leila Adesse, Claudia Bonan Jannotti, Katia Silveira da Silva, Vania Matos Fonseca
This article analyzes the scientific output on abortion and social stigma and the potential of the stigma category for abortion care in Brazil. An integrative review of publications on scientific databases without a time limit was conducted. Sixty-five publications with the social representations of women who had an abortion and the professionals who attended them were analyzed. The obstacles to the implementation of abortion laws and the protocols and norms that facilitate access to quality services care was explored...
December 2016: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/27924172/hyaluronic-acid-fat-graft-myringoplasty-versus-autologous-platelet-rich-plasma
#13
Salman F Alhabib, Issam Saliba
BACKGROUND: Hyaluronic acid fat graft myringoplasty (HAFGM) is an office-based technique for tympanic membrane perforation (TMP) treatment. It is simple, inexpensive, and performed under local anesthesia at the outpatient office department. We aimed to compare HAFGM technique to a recently described topical use of autologous platelet rich plasma myringoplasty (PRPM) in the repair of TMP. We also aimed to assess the hearing level improvement postoperatively. METHODS: We conducted a prospective study in an adult tertiary care center between January 2015 and January 2016...
January 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27923388/dimensions-of-patient-satisfaction-with-comprehensive-abortion-care-in-addis-ababa-ethiopia
#14
Bekalu Mossie Chekol, Dame Abera Abdi, Tamirie Andualem Adal
BACKGROUND: Patient satisfaction is a measure of the extent to which a patient is content with the health care received from health care providers. It has been recognized as one of the most vital indicators of quality. Hence, it has been studied and measured extensively as part of service quality and as a standalone construct. In spite of this, there has been limited or no studies in Ethiopia that describe factors of abortion care contributed to women's satisfaction. This study aimed to identifying the underlying factors that contribute to patient satisfaction with comprehensive abortion care and at exploring relationships between total satisfaction scores and socio-demographic and care-related variables in Addis Ababa, Ethiopia...
December 7, 2016: Reproductive Health
https://www.readbyqxmd.com/read/27921037/acute-kidney-injury-in-western-countries
#15
REVIEW
Josée Bouchard, Ravindra L Mehta
BACKGROUND: Acute kidney injury (AKI) is frequent and is associated with poor outcomes, including increased mortality, higher risk of chronic kidney disease, and prolonged hospital lengths of stay. The epidemiology of AKI mainly derives from studies performed in Western high-income countries. More limited data are available from Western low-income and middle-income countries (LMICs) located in Central and South America. SUMMARY: In this review, we summarize the most recent data on the epidemiology of AKI in Western countries, aiming to contrast results from industrialized high-income countries with LMICs...
October 2016: Kidney Diseases
https://www.readbyqxmd.com/read/27921036/acute-kidney-injury-in-asia
#16
REVIEW
Li Yang
BACKGROUND: Acute kidney injury (AKI) is a common disorder and is associated with a high morbidity and mortality worldwide. The diversity of the climate and of the socioeconomic and developmental status in Asia has a great influence on the etiology and presentation of AKI in different regions. In view of the International Society of Nephrology's 0by25 initiative, more and more attention has been paid to AKI in Asian countries. SUMMARY: In this review, we summarize the recent achievements with regard to the prevalence and clinical patterns of AKI in Asian countries...
October 2016: Kidney Diseases
https://www.readbyqxmd.com/read/27913574/intended-and-unintended-consequences-of-abortion-law-reform-perspectives-of-abortion-experts-in-victoria-australia
#17
L A Keogh, D Newton, C Bayly, K McNamee, A Hardiman, A Webster, M Bismark
INTRODUCTION: In Victoria, Australia, abortion was decriminalised in October 2008, bringing the law in line with clinical practice and community attitudes. We describe how experts in abortion service provision perceived the intent and subsequent impact of the 2008 Victorian abortion law reform. METHODS: Experts in abortion provision in Victoria were recruited for a qualitative semi-structured interview about the 2008 law reform and its perceived impact, until saturation was reached...
January 2017: Journal of Family Planning and Reproductive Health Care
https://www.readbyqxmd.com/read/27913060/outcome-of-pregnancy-and-neonatal-complications-with-anti-tumor-necrosis-factor-%C3%AE-use-in-females-with-immune-mediated-diseases-a-systematic-review-and-meta-analysis
#18
REVIEW
Fukiko Komaki, Yuga Komaki, Dejan Micic, Akio Ido, Atsushi Sakuraba
BACKGROUND: Immune mediated diseases such as rheumatoid arthritis (RA), ankylosing spondylitis (AS), and inflammatory bowel disease (IBD) commonly affect young and adolescent females. Anti-tumor necrosis factor (TNF)-α agents are increasingly used to treat these conditions, but their safety during pregnancy remains unclear. OBJECTIVES: To evaluate the risk of pregnancy related outcomes in patients with various immune mediated diseases treated with anti-TNF-α agents...
January 2017: Journal of Autoimmunity
https://www.readbyqxmd.com/read/27903078/why-prevention-of-repeat-abortion-is-so-challenging-psychosocial-characteristics-of-women-at-risk
#19
Brigitte Leeners, Simone Bieli, Dorothy Huang, Sibil Tschudin
OBJECTIVES: Abortion rates have declined in recent decades; however, the rate of repeat abortion remains high. In order to identify keys to making efficient interventions against repeat abortion, our objectives were: to assess the percentage of repeat abortions in women opting for termination of pregnancy over a period of 1 year; to identify the risk factors for repeat abortion; and to assess the characteristics of women who opted for a further pregnancy termination despite having received standard post-abortion care...
November 30, 2016: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/27898721/hepatitis-b-virus-infections-and-associated-factors-among-pregnant-women-attending-antenatal-care-clinic-at-deder-hospital-eastern-ethiopia
#20
Abdi Umare, Berhanu Seyoum, Tesfaye Gobena, Tamirat Haile Mariyam
BACKGROUND: Hepatitis B virus (HBV) infection is a serious public health problem worldwide. Reports have shown that 68,600 people die of HBV infection and more than 300,000 deaths due to liver cancer secondary to hepatitis B every year globally. Women who are infected with HBV can vertically transmit the infection to their infants. This study aims to determine the prevalence of HBV infection and associated factors among pregnant women. METHODS AND FINDINGS: A hospital-based cross-sectional study was conducted among pregnant women who attended antenatal care clinic (ANC) for routine pregnancy check-up between 18 March 2015 and 15 May 2015...
2016: PloS One
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