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https://www.readbyqxmd.com/read/28331631/improving-medication-management-for-patients-with-multimorbidity-in-primary-care-a-qualitative-feasibility-study-of-the-my-comrade-implementation-intervention
#1
Carol Sinnott, Molly Byrne, Colin P Bradley
BACKGROUND: For the majority of patients with multimorbidity, the prescription of multiple long-term medications (polypharmacy) is indicated. However, polypharmacy poses a risk of adverse drug events, drug interactions and excessive treatment burdens. To help general practitioners (GPs) conduct more comprehensive medication reviews for patients with multimorbidity, we developed the theoretically-informed MultimorbiditY COllaborative Medication Review And DEcision Making (MY COMRADE) implementation intervention...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28318461/the-event-chain-of-survival-in-the-context-of-music-festivals-a-framework-for-improving-outcomes-at-major-planned-events
#2
Adam Lund, Sheila Turris
Despite the best efforts of event producers and on-site medical teams, there are sometimes serious illnesses, life-threatening injuries, and fatalities related to music festival attendance. Producers, clinicians, and researchers are actively seeking ways to reduce the mortality and morbidity associated with these events. After analyzing the available literature on music festival health and safety, several major themes emerged. Principally, stakeholder groups planning in isolation from one another (ie, in silos) create fragmentation, gaps, and overlap in plans for major planned events (MPEs)...
March 20, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28298265/supervised-machine-learning-algorithms-can-classify-open-text-feedback-of-doctor-performance-with-human-level-accuracy
#3
Chris Gibbons, Suzanne Richards, Jose Maria Valderas, John Campbell
BACKGROUND: Machine learning techniques may be an effective and efficient way to classify open-text reports on doctor's activity for the purposes of quality assurance, safety, and continuing professional development. OBJECTIVE: The objective of the study was to evaluate the accuracy of machine learning algorithms trained to classify open-text reports of doctor performance and to assess the potential for classifications to identify significant differences in doctors' professional performance in the United Kingdom...
March 15, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28297309/production-review-and-impact-of-technical-quality-control-guidelines-in-a-national-context
#4
Michelle K Nielsen, Kyle E Malkoske, Erika Brown, Kevin Diamond, Normand Frenière, John Grant, Natalie Pomerleau-Dalcourt, Jason Schella, L John Schreiner, Laurent Tantôt, J Eduardo Villarreal-Barajas, Jean-Pierre Bissonnette
A close partnership between the Canadian Partnership for Quality Radiotherapy (CPQR) and the Canadian Organization of Medical Physicist's (COMP) Quality Assurance and Radiation Safety Advisory Committee (QARSAC) has resulted in the development of a suite of Technical Quality Control (TQC) guidelines for radiation treatment equipment; they outline specific performance objectives and criteria that equipment should meet in order to assure an acceptable level of radiation treatment quality. The adopted framework for the development and maintenance of the TQCs ensures the guidelines incorporate input from the medical physics community during development, measures the workload required to perform the QC tests outlined in each TQC, and remain relevant (i...
November 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28296781/efficacy-and-safety-of-medical-therapy-for-low-bone-mineral-density-in-patients-with-crohn-disease-a-systematic-review-with-network-meta-analysis
#5
Xiaojing Zhao, Changcheng Zhou, Han Chen, Jingjing Ma, Yunjuan Zhu, Peixue Wang, Yi Zhang, Haiqin Ma, Hongjie Zhang
BACKGROUND: Low bone mineral density (BMD) is a frequent complication of inflammatory bowel disease (IBD), particularly in patients with Crohn disease (CD). The aim of our study is to determine the efficacy and safety of different drugs used to treat low BMD in patients with CD. METHODS: PUBMED/MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials were searched for eligible studies. A random-effects model within a Bayesian framework was applied to compare treatment effects as standardized mean difference (SMD) with their corresponding 95% credible interval (CrI), while odds ratio (OR) was applied to compare adverse events with 95% CrI...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28294382/the-role-of-morbidity-and-mortality-rounds-in-medical-education-a-scoping-review
#6
REVIEW
Paul Benassi, Lindsey MacGillivray, Ivan Silver, Sanjeev Sockalingam
CONTEXT: There is increasing focus on how health care professionals can be trained effectively in quality improvement and patient safety principles. The morbidity and mortality round (MMR) has often been used as a tool with which to examine and teach care quality, yet little is known of its implementation and educational outcomes. OBJECTIVES: The objectives of this scoping review are to examine and summarise the literature on how the MMR is designed and delivered, and to identify how it is evaluated for effectiveness in addressing medical education outcomes...
March 14, 2017: Medical Education
https://www.readbyqxmd.com/read/28291189/orthopaedic-device-approval-through-the-premarket-approval-process-a-financial-feasibility-analysis-for-a-single-center
#7
Brian W Yang, Matthew L Iorio, Charles S Day
The 2 main routes of medical device approval through the U.S. Food and Drug Administration are the premarket approval (PMA) process, which requires clinical trials, and the 510(k) premarket notification, which exempts devices from clinical trials if they are substantially equivalent to an existing device. Recently, there has been growing concern regarding the safety of devices approved through the 510(k) premarket notification. The PMA process decreases the potential for device recall; however, it is substantially more costly and time-consuming...
March 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28270198/large-scale-adverse-effects-related-to-treatment-evidence-standardization-laertes-an-open-scalable-system-for-linking-pharmacovigilance-evidence-sources-with-clinical-data
#8
(no author information available yet)
BACKGROUND: Integrating multiple sources of pharmacovigilance evidence has the potential to advance the science of safety signal detection and evaluation. In this regard, there is a need for more research on how to integrate multiple disparate evidence sources while making the evidence computable from a knowledge representation perspective (i.e., semantic enrichment). Existing frameworks suggest well-promising outcomes for such integration but employ a rather limited number of sources...
March 7, 2017: Journal of Biomedical Semantics
https://www.readbyqxmd.com/read/28269568/smartphone-based-swallowing-monitoring-and-feedback-device-for-mealtime-assistance-in-nursing-homes
#9
Naomi Kuramoto, Dushyantha Jayatilake, Kikue Hidaka, Kenji Suzuki
As many of the elderly are prone to dysphagia, preventing aspirations during mealtime assistance is a huge concern, especially for institutions operated with limited staff. Two of the main course of actions that are taken usually to prevent aspiration are the altering of bolus consistency and altering of the swallowing posture. To assist prevention of pneumonia, we have been developing a smartphone-based wearable technology that can evaluate swallowing ability in real-time. In this paper we will introduce modified version of Swallwoscope adding a posture detection system and a remote swallowing activity visualisation system to our previous work...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28259712/molecular-docking-synthesis-and-biological-screening-of-mefenamic-acid-derivatives-as-anti-inflammatory-agents
#10
Jignasa K Savjani, Suja Mulamkattil, Bhavesh Variya, Snehal Patel
Drug induced gastrointestinal ulceration, renal side effects and hepatotoxicity are the main causes of numerous Non-Steroidal Anti-inflammatory Drugs (NSAIDs). Cyclooxygenase-2 (COX-2) inhibitors discovered to decrease the gastrointestinal issues, but unfortunately, most of them are associated with major cardiovascular adverse effects. Along these lines, various new strategies and frameworks were developed wherein basic alterations of the present medications were accounted for. The aim of the study was to prepare derivatives of mefenamic acid to evaluate anti-inflammatory activity with fewer adverse reactions...
March 1, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28244828/insurance-systems-and-reimbursement-concerning-research-and-development-of-regenerative-medicine-in-japan
#11
Kiyoshi Okada, Toshio Miyata, Yoshiki Sawa
In Japan, the Act on the Safety of Regenerative Medicine and the Pharmaceuticals, Medical Devices and Other Therapeutic Products Act were enacted in November 2014, creating a new framework for clinical research and products related to regenerative medicine. Together with these regulatory frameworks, new insurance procedures were created for handling regenerative medicine in Japan. For developing regenerative medicine in Japan, understanding medical insurance greatly influences funding and venture success, particularly in the stages between clinical research and market launch...
March 2017: Regenerative Medicine
https://www.readbyqxmd.com/read/28242191/comprehensive-literature-review-of-factors-influencing-medication-safety-in-nursing-homes-using-a-systems-model
#12
REVIEW
Ali Azeez Al-Jumaili, William R Doucette
OBJECTIVES: The objectives of this review were to identify the work system factors influencing medication safety measures [adverse drug events (ADEs), adverse drug reactions, or medication errors (MEs)], to determine the incidence of ADEs, and describe the most common ADEs in nursing homes (NHs). METHODS: A comprehensive literature review was conducted using PubMed and CINAHL to identify studies investigating factors that influence ADEs, adverse drug reactions, and MEs in NHs and skilled nursing facilities...
February 24, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28227823/smartphone-based-swallowing-monitoring-and-feedback-device-for-mealtime-assistance-in-nursing-homes
#13
Naomi Kuramoto, Dushyantha Jayatilake, Kikue Hidaka, Kenji Suzuki, Naomi Kuramoto, Dushyantha Jayatilake, Kikue Hidaka, Kenji Suzuki, Kenji Suzuki, Kikue Hidaka, Dushyantha Jayatilake, Naomi Kuramoto
As many of the elderly are prone to dysphagia, preventing aspirations during mealtime assistance is a huge concern, especially for institutions operated with limited staff. Two of the main course of actions that are taken usually to prevent aspiration are the altering of bolus consistency and altering of the swallowing posture. To assist prevention of pneumonia, we have been developing a smartphone-based wearable technology that can evaluate swallowing ability in real-time. In this paper we will introduce modified version of Swallwoscope adding a posture detection system and a remote swallowing activity visualisation system to our previous work...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28219432/personalized-heterogeneous-deformable-model-for-fast-volumetric-registration
#14
Weixin Si, Xiangyun Liao, Qiong Wang, Pheng Ann Heng
BACKGROUND: Biomechanical deformable volumetric registration can help improve safety of surgical interventions by ensuring the operations are extremely precise. However, this technique has been limited by the accuracy and the computational efficiency of patient-specific modeling. METHODS: This study presents a tissue-tissue coupling strategy based on penalty method to model the heterogeneous behavior of deformable body, and estimate the personalized tissue-tissue coupling parameters in a data-driven way...
February 20, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28214491/relationship-between-patient-reported-symptoms-limitations-in-daily-activities-and-psychological-impact-in-varicose-veins
#15
Rajiv Mallick, Brajesh Kumar Lal, Claire Daugherty
OBJECTIVE: The objective of this study was to evaluate the relationship between patient-reported symptoms, functional limitations, and psychological impact of varicose veins (VVs) vs pathophysiologic mechanism, incorporating demographic and behavioral factors. METHODS: We conducted a pooled analysis from two clinical studies (Efficacy and Safety Study of Polidocanol Injectable Foam for the Treatment of Saphenofemoral Junction Incompetence [VANISH-1] and Polidocanol Endovenous Microfoam Versus Vehicle for the Treatment of Saphenofemoral Junction Incompetence [VANISH-2]) in patients with VVs (superficial venous reflux only)...
March 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28191324/effect-of-logarithmic-and-linear-frequency-scales-on-parametric-modelling-of-tissue-dielectric-data
#16
Saqib Salahuddin, Emily Porter, Paul M Meaney, Martin O'Halloran
The dielectric properties of biological tissues have been studied widely over the past half-century. These properties are used in a vast array of applications, from determining the safety of wireless telecommunication devices to the design and optimisation of medical devices. The frequency-dependent dielectric properties are represented in closed-form parametric models, such as the Cole-Cole model, for use in numerical simulations which examine the interaction of electromagnetic (EM) fields with the human body...
February 2017: Biomedical Physics & Engineering Express
https://www.readbyqxmd.com/read/28186072/the-evolving-role-of-medical-scribe-variation-and-implications-for-organizational-effectiveness-and-safety
#17
Deborah V Woodcock, Robert Pranaat, Karess McGrath, Joan S Ash
Increasing use of medical scribes is an unintended consequence of electronic health record adoption in the U.S. The role of scribe is not universally defined, leading to variations in scribe training and operations, as well as questions about scribe efficiency, effectiveness, and safety. Studies published since 2009 have primarily focused on the financial aspects of scribe use, but no published studies have taken an organizational view of this phenomenon. This paper describes stakeholder perspectives on scribes working in outpatient settings within an urban tertiary academic medical center...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28181853/identifying-facilitators-and-barriers-for-implementation-of-interprofessional-education-perspectives-from-medical-educators-in-the-netherlands
#18
Joy de Vries-Erich, Kirsten Reuchlin, Paul de Maaijer, J M Monica van de Ridder
Patient care and patient safety can be compromised by the lack of interprofessional collaboration and communication between healthcare providers. Interprofessional education (IPE) should therefore start during medical training and not be postponed until after graduation. This case study explored the current situation in the Dutch context and interviewed experts within medical education and with pioneers of successful best practices to learn more about their experiences with IPE. Data analysis started while new data were still collected, resulting in an iterative, constant comparative process...
March 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/28166784/randomized-controlled-trial-of-a-coordinated-care-intervention-to-improve-risk-factor-control-after-stroke-or-transient-ischemic-attack-in-the-safety-net-secondary-stroke-prevention-by-uniting-community-and-chronic-care-model-teams-early-to-end-disparities
#19
RANDOMIZED CONTROLLED TRIAL
Amytis Towfighi, Eric M Cheng, Monica Ayala-Rivera, Heather McCreath, Nerses Sanossian, Tara Dutta, Bijal Mehta, Robert Bryg, Neal Rao, Shlee Song, Ali Razmara, Magaly Ramirez, Theresa Sivers-Teixeira, Jamie Tran, Elizabeth Mojarro-Huang, Ana Montoya, Marilyn Corrales, Beatrice Martinez, Phyllis Willis, Mireya Macias, Nancy Ibrahim, Shinyi Wu, Jeremy Wacksman, Hilary Haber, Adam Richards, Frances Barry, Valerie Hill, Brian Mittman, William Cunningham, Honghu Liu, David A Ganz, Diane Factor, Barbara G Vickrey
BACKGROUND: Recurrent strokes are preventable through awareness and control of risk factors such as hypertension, and through lifestyle changes such as healthier diets, greater physical activity, and smoking cessation. However, vascular risk factor control is frequently poor among stroke survivors, particularly among socio-economically disadvantaged blacks, Latinos and other people of color. The Chronic Care Model (CCM) is an effective framework for multi-component interventions aimed at improving care processes and outcomes for individuals with chronic disease...
February 6, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28159447/medical-device-guidebook-a-browser-information-resource-for-medical-device-users
#20
Douglas M Clarkson
A web based information resource - the 'Medical Device Guidebook' - for the enabling of safe use of medical devices is described. Medical devices are described within a 'catalogue' of specific models and information on a specific model is provided within a consistent set of information 'keys'. These include 'user manuals', 'points of caution', 'clinical use framework', 'training/assessment material', 'frequently asked questions', 'authorised user comments' and 'consumables'. The system allows identification of known risk/hazards associated with specific devices, triggered, for example, by national alerts or locally raised safety observations...
January 31, 2017: Medical Engineering & Physics
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