keyword
MENU ▼
Read by QxMD icon Read
search

framework medication safety

keyword
https://www.readbyqxmd.com/read/29760661/a-semantic-transformation-methodology-for-the-secondary-use-of-observational-healthcare-data-in-postmarketing-safety-studies
#1
Anil Pacaci, Suat Gonul, A Anil Sinaci, Mustafa Yuksel, Gokce B Laleci Erturkmen
Background: Utilization of the available observational healthcare datasets is key to complement and strengthen the postmarketing safety studies. Use of common data models (CDM) is the predominant approach in order to enable large scale systematic analyses on disparate data models and vocabularies. Current CDM transformation practices depend on proprietarily developed Extract-Transform-Load (ETL) procedures, which require knowledge both on the semantics and technical characteristics of the source datasets and target CDM...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29751347/effects-of-varenicline-on-subjective-craving-and-relative-reinforcing-value-of-cigarettes
#2
ReJoyce Green, Lara A Ray
BACKGROUND: Varenicline is an FDA approved medication for the treatment of nicotine dependence. While the efficacy and safety of this medication have been demonstrated, success rates remain low, and efforts to understand mechanisms of efficacy are in progress. A behavioral economics framework is one unique way to examine how demand for a drug changes under different circumstances. Therefore, the current randomized placebo-controlled, cross-over study aimed to examine effects of varenicline on subjective cigarette craving and objective demand for cigarettes measured by a hypothetical behavioral economic task as well as associations between subjective craving and objective demand...
April 30, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29735477/finding-meaning-in-medication-reconciliation-using-electronic-health-records-qualitative-analysis-in-safety-net-primary-and-specialty-care
#3
George Yaccoub Matta, Elaine C Khoong, Courtney R Lyles, Dean Schillinger, Neda Ratanawongsa
BACKGROUND: Safety net health systems face barriers to effective ambulatory medication reconciliation for vulnerable populations. Although some electronic health record (EHR) systems offer safety advantages, EHR use may affect the quality of patient-provider communication. OBJECTIVE: This mixed-methods observational study aimed to develop a conceptual framework of how clinicians balance the demands and risks of EHR and communication tasks during medication reconciliation discussions in a safety net system...
May 7, 2018: JMIR Medical Informatics
https://www.readbyqxmd.com/read/29731369/tailored-frequency-escalated-primary-prophylaxis-for-severe-haemophilia-a-results-of-the-16-year-canadian-hemophilia-prophylaxis-study-longitudinal-cohort
#4
Brian M Feldman, Georges E Rivard, Paul Babyn, John K M Wu, MacGregor Steele, Man-Chiu Poon, Robert T Card, Sara J Israels, Nicole Laferriere, Kulwant Gill, Anthony K Chan, Manuel Carcao, Robert J Klaassen, Stephanie Cloutier, Victoria E Price, Saunya Dover, Victor S Blanchette
BACKGROUND: Severe haemophilia A has high morbidity, and treatment, while effective, is very expensive. We report the 16-year follow-up of the Canadian Hemophilia Prophylaxis Study, which examined the effectiveness of tailored frequency-escalated primary prophylaxis with a focus on health outcomes within the domains of body structures and functions, and activities and participation (according to the WHO International Classification of Functioning, Disability and Health [WHO-ICF] framework) and a view to reducing consumption of costly clotting factor, which accounts for more than 90% of the cost of care of severe haemophilia...
May 3, 2018: Lancet Haematology
https://www.readbyqxmd.com/read/29730617/what-is-the-epidemiology-of-medication-errors-error-related-adverse-events-and-risk-factors-for-errors-in-adults-managed-in-community-care-contexts-a-systematic-review-of-the-international-literature
#5
Ghadah Asaad Assiri, Nada Atef Shebl, Mansour Adam Mahmoud, Nouf Aloudah, Elizabeth Grant, Hisham Aljadhey, Aziz Sheikh
OBJECTIVE: To investigate the epidemiology of medication errors and error-related adverse events in adults in primary care, ambulatory care and patients' homes. DESIGN: Systematic review. DATA SOURCE: Six international databases were searched for publications between 1 January 2006 and 31 December 2015. DATA EXTRACTION AND ANALYSIS: Two researchers independently extracted data from eligible studies and assessed the quality of these using established instruments...
May 5, 2018: BMJ Open
https://www.readbyqxmd.com/read/29714608/a-comparative-study-of-medical-device-regulations-us-europe-canada-and-taiwan
#6
Yi-Jung Chen, Chi-Ming Chiou, Yu-Wen Huang, Pei-Weng Tu, Yung-Chuan Lee, Chia-Hung Chien
The medical device industry is an industry dealing with multiple types of products covering a wide range of applications. As the safety and effectiveness of medical devices are vital to human health, the products must be managed by strict regulations according to the different risk levels. A total product life cycle regulatory system including product design, manufacture, premarket gate keeping, and postmarket monitoring is a common framework for medical device regulations. However, the variety and innovativeness of medical devices are challenging the current regulatory frameworks...
January 2018: Therapeutic Innovation & Regulatory Science
https://www.readbyqxmd.com/read/29714563/the-safety-explorer-suite-interactive-safety-monitoring-for-clinical-trials
#7
Jeremy Wildfire, Ryan Bailey, Rebecca Z Krouse, Spencer Childress, Britt Sikora, Nathan Bryant, Shane Rosanbalm, Emily Wilson, Jack G Modell
BACKGROUND: Frequent and thorough monitoring of patient safety is a requirement of clinical trials research. Safety data are traditionally reported in a tabular or listing format, which often translates into many pages of static displays. This poses the risk that clinically relevant signals will be obscured by the sheer volume of data reported. Interactive graphics enable the delivery of the vast scope of information found in traditional reports, but allow the user to interact with the charts in real time, focusing on signals of interest...
January 1, 2018: Therapeutic Innovation & Regulatory Science
https://www.readbyqxmd.com/read/29708437/adapting-maslow-s-hierarchy-of-needs-as-a-framework-for-resident-wellness
#8
Andrew J Hale, Daniel N Ricotta, Jason Freed, C Christopher Smith, Grace C Huang
ISSUE: Burnout in graduate medical education is pervasive and has a deleterious impact on career satisfaction, personal well-being, and patient outcomes. Interventions in residency programs have often addressed isolated contributors to burnout; however, a more comprehensive framework for conceptualizing wellness is needed. EVIDENCE: In this article the authors propose Maslow's hierarchy of human needs (physiologic, safety, love/belonging, esteem, and self-actualization) as a potential framework for addressing wellness initiatives...
April 30, 2018: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/29704184/venous-thromboembolism-prophylaxis-in-mental-health-in-patient-services-a-qualitative-study
#9
Audrey Purcell, Mary Clarke, Ian Maidment
Background Venous thromboembolism (VTE) is an important and potentially preventable cause of morbidity and mortality in hospitalised patients. It is a significant, international patient safety issue affecting medical, surgical and mental health in-patients. There is a paucity of published evidence on the incidence of VTE, and the role of VTE risk-assessment and prophylaxis, in mental healthcare settings. Epidemiological evidence indicates that antipsychotic medications are an independent risk factor for VTE...
April 27, 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29699556/the-struggle-against-perceived-negligence-a-qualitative-study-of-patients-experiences-of-adverse-events-in-norwegian-hospitals
#10
Gunn Hågensen, Gudrun Nilsen, Grete Mehus, Nils Henriksen
BACKGROUND: Every year, 14 % of patients in Norwegian hospitals experience adverse events, which often have health-damaging consequences. The government, hospital management and health personnel attempt to minimize such events. Limited research on the first-hand experience of the patients affected is available. The aim of this study is to present patients' perspectives of the occurrence of, disclosure of, and healthcare organizations' responses to adverse events. Findings are discussed within a social constructivist framework and with reference to principles of open disclosure policy...
April 25, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29669706/reasons-for-physicians-not-adopting-clinical-decision-support-systems-critical-analysis
#11
REVIEW
Saif Khairat, David Marc, William Crosby, Ali Al Sanousi
BACKGROUND: Clinical decision support systems (CDSSs) are an integral component of today's health information technologies. They assist with interpretation, diagnosis, and treatment. A CDSS can be embedded throughout the patient safety continuum providing reminders, recommendations, and alerts to health care providers. Although CDSSs have been shown to reduce medical errors and improve patient outcomes, they have fallen short of their full potential. User acceptance has been identified as one of the potential reasons for this shortfall...
April 18, 2018: JMIR Medical Informatics
https://www.readbyqxmd.com/read/29664187/exercise-interventions-and-patient-beliefs-for-people-with-hip-knee-or-hip-and-knee-osteoarthritis-a-mixed-methods-review
#12
REVIEW
Michael Hurley, Kelly Dickson, Rachel Hallett, Robert Grant, Hanan Hauari, Nicola Walsh, Claire Stansfield, Sandy Oliver
BACKGROUND: Chronic peripheral joint pain due to osteoarthritis (OA) is extremely prevalent and a major cause of physical dysfunction and psychosocial distress. Exercise is recommended to reduce joint pain and improve physical function, but the effect of exercise on psychosocial function (health beliefs, depression, anxiety and quality of life) in this population is unknown. OBJECTIVES: To improve our understanding of the complex inter-relationship between pain, psychosocial effects, physical function and exercise...
April 17, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29659675/facing-the-inevitable-being-prepared-for-regulatory-requirements-for-laboratory-developed-tests
#13
Rita D'Angelo, Ronald Weiss, David Wolfe, Ratna Chinnam, Alper Murat, Julia Gluesing, Toni Somers
Objectives: We introduce regulatory terms, definitions, and the Quality System Regulation as proposed by the US Food and Drug Administration in the 2014 draft guidance entitled Framework for Regulatory Oversight of Laboratory Developed Tests and explore medical device requirements applicable to a laboratory environment to design, develop, and validate laboratory developed tests (LDTs). Methods: We performed nine interviews with laboratory professionals to explore concerns and challenges regarding the draft, translated the results into operational factors, and surveyed professionals to test the factors that would comprise a regulatory quality management system framework...
April 25, 2018: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29659069/regulating-mobile-mental-health-apps
#14
Nicolas P Terry, Tracy D Gunter
Mobile medical apps (MMAs) are a fast-growing category of software typically installed on personal smartphones and wearable devices. A subset of MMAs are aimed at helping consumers identify mental states and/or mental illnesses. Although this is a fledgling domain, there are already enough extant mental health MMAs both to suggest a typology and to detail some of the regulatory issues they pose. As to the former, the current generation of apps includes those that facilitate self-assessment or self-help, connect patients with online support groups, connect patients with therapists, or predict mental health issues...
March 2018: Behavioral Sciences & the Law
https://www.readbyqxmd.com/read/29649231/application-of-quality-by-design-for-3d-printed-bone-prostheses-and-scaffolds
#15
Daniel Martinez-Marquez, Ali Mirnajafizadeh, Christopher P Carty, Rodney A Stewart
3D printing is an emergent manufacturing technology recently being applied in the medical field for the development of custom bone prostheses and scaffolds. However, successful industry transformation to this new design and manufacturing approach requires technology integration, concurrent multi-disciplinary collaboration, and a robust quality management framework. This latter change enabler is the focus of this study. While a number of comprehensive quality frameworks have been developed in recent decades to ensure that the manufacturing of medical devices produces reliable products, they are centred on the traditional context of standardised manufacturing techniques...
2018: PloS One
https://www.readbyqxmd.com/read/29602938/ensuring-right-to-organic-food-in-public-health-system
#16
Vitalii Pashkov, Olena Batyhina, Liudmyla Leiba
OBJECTIVE: Introduction: Human health directly depends on safety and quality of food. In turn, quality and safety of food directly depend on its production conditions and methods. There are two main food production methods: traditional and organic. Organic food production is considered safer and more beneficial for human health. Aim: to determine whether the organic food production method affects human health. PATIENTS AND METHODS: Materials and methods: international acts, data of international organizations and conclusions of scientists have been examined and used in the study...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29589781/physicians-perspectives-of-pharmacist-physician-collaboration-in-the-united-arab-emirates-findings-from-an-exploratory-study
#17
S Hasan, K Stewart, C B Chapman, D C M Kong
Interprofessional collaborative care has been shown to improve patient outcomes. Physicians' views on collaboration with pharmacists give an insight into what contributes to a well-functioning team. Little is known about these views from low and ​middle-income countries and nothing from the United Arab Emirates (UAE). The purpose of this study is to investigate physicians' opinions on collaborative relationships with community pharmacists in the UAE. Semi-structured individual interviews and group discussions are conducted with a purposive sample of physicians...
March 28, 2018: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/29587730/applying-interprofessional-team-based-learning-in-patient-safety-a-pilot-evaluation-study
#18
Lukas Lochner, Sandra Girardi, Alessandra Pavcovich, Horand Meier, Franco Mantovan, Dietmar Ausserhofer
BACKGROUND: Interprofessional education (IPE) interventions are not always successful in achieving learning outcomes. Team-Based Learning (TBL) would appear to be a suitable pedagogical method for IPE, as it focuses on team performance; however, little is known about interprofessional TBL as an instructional framework for patient safety. In this pilot-study, we aimed to (1) describe participants' reactions to TBL, (2) observe their achievement with respect to interprofessional education learning objectives, and (3) document their attitudinal shifts with regard to patient safety behaviours...
March 27, 2018: BMC Medical Education
https://www.readbyqxmd.com/read/29580114/athletes-and-supplements-prevalence-and-perspectives
#19
Ina Garthe, Ronald J Maughan
In elite sport, where opponents are evenly matched, small factors can determine the outcome of sporting contests. Not all athletes know the value of making wise nutrition choices, but anything that might give a competitive edge, including dietary supplements, can seem attractive. Between 40% and 100% of athletes typically use supplements, depending on the type of sport, level of competition, and the definition of supplements. However, unless the athlete has a nutrient deficiency, supplementation may not improve performance and may have a detrimental effect on both performance and health...
March 26, 2018: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29579446/the-hidden-cost-of-regulation-the-administrative-cost-of-reporting-serious-reportable-events
#20
Bonnie B Blanchfield, Bijay Acharya, Elizabeth Mort
BACKGROUND: More than half of the 50 states (27) and the District of Columbia require reporting of Serous Reportable Events (SREs). The goal is to hold providers accountable and improve patient safety, but there is little information about the administrative cost of this reporting requirement. This study was conducted to identify costs associated with investigating and reporting SREs. METHODS: This qualitative study used case study methods that included interviewing staff and review of data and documents to investigate each SRE occurring at one academic medical center during fiscal year 2013...
April 2018: Joint Commission Journal on Quality and Patient Safety
keyword
keyword
72685
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"