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https://www.readbyqxmd.com/read/29332093/structure-function-correlation-in-hemianopic-vision-loss-in-children-aged-3-6-years-using-oct-and-svop-and-comparison-with-adult-eyes
#1
Wadim Bowl, Robert Knobloch, Silke Schweinfurth, Kerstin Holve, Knut Stieger, Birgit Lorenz
PURPOSE: To correlate visual field assessment with saccadic vector optokinetic perimetry (SVOP) in children with ganglion cell loss due to anterior pathway pathologies resulting in hemianopic visual field defects measured with optical coherence tomography (OCT). METHODS: 5 young (aged 3-6 years) and 5 adult patients with hemianopia, 10 healthy preschoolers (mean age 4.4 years), and 10 healthy adults (mean age 25.3 years) were tested with SVOP and OCT (focusing on the ganglion cell layer, GCL+)...
January 13, 2018: Ophthalmic Research
https://www.readbyqxmd.com/read/29328530/fusing-planar-group-to-a-pi-bowl-electronic-and-molecular-structure-aromaticity-and-solid-state-packing-of-naphthocorannulene-and-its-anions
#2
Zheng Zhou, Sarah Spisak, Qi Xu, Andrey Rogachev, Zheng Wei, Massimo Marcaccio, Marina A Petrukhina
Molecular and electronic structure, reduction and coordination abilities of a PAH having a planar naphtho-group fused to the corannulene bowl have been investigated for the first time using a combination of theoretical and experimental tools. A direct comparison of naphtho[2,3-a]corannulene (C28H14, 1) with parent corannulene (C20H10, 2) revealed the effect of framework topology change on electronic properties and aromaticity of 1. Two reversible one-electron reduction processes with the formal reduction potentials at -2...
January 12, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29323236/molecular-determinants-of-ca2-sensitivity-at-the-intersubunit-interface-of-the-bk-channel-gating-ring
#3
Qin Li, Yingxin Li, Hua Wei, Hao-Min Pan, Alexandre G Vouga, Brad S Rothberg, Yunkun Wu, Jiusheng Yan
The large-conductance calcium-activated K+ (BK) channel contains two intracellular tandem Ca2+-sensing RCK domains (RCK1 and RCK2), which tetramerize into a Ca2+ gating ring that regulates channel opening by conformational expansion in response to Ca2+ binding. Interestingly, the gating ring's intersubunit assembly interface harbors the RCK2 Ca2+-binding site, known as the Ca2+ bowl. The gating ring's assembly interface is made in part by intersubunit coordination of a Ca2+ ion between the Ca2+ bowl and an RCK1 Asn residue, N449, and by apparent intersubunit electrostatic interactions between E955 in RCK2 and R786 and R790 in the RCK2 of the adjacent subunit...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29317934/the-impact-of-pharmacists-as-immunizers-in-collaborative-community-offsite-pharmacy-practice-co-opp-phase-1
#4
Susan E Beresford, Jennine P Crawshaw, Susan K Bowles, Jennifer E Isenor
No abstract text is available yet for this article.
January 2018: Canadian Pharmacists Journal: CPJ, Revue des Pharmaciens du Canada: RPC
https://www.readbyqxmd.com/read/29316334/geriatric-assessment-of-physical-and-cognitive-functioning-in-a-diverse-cohort-of-systemic-lupus-erythematosus-patients-a-pilot-study
#5
Laura Plantinga, Benjamin D Tift, Charmayne Dunlop-Thomas, S Sam Lim, C Barrett Bowling, Cristina Drenkard
OBJECTIVE: To use multi-domain functional assessment, commonly performed in geriatric patients but novel among SLE patients, to better understand functional impairment in SLE. METHODS: We recruited 60 adult participants [aged 20-39 (26.7%), 40-59 (50.0%), and ≥60 (23.3%); 80.0% black; 90.0% female] from an existing cohort of SLE patients. During in-person visits (10/16-4/17), we evaluated physical performance (range 0-4; higher scores = better performance); cognitive performance (five fluid cognition domains; adjusted t-scores); and self-reported measures including physical functioning (t-scores), activities of daily living (ADLs), falls, and life-space mobility...
January 5, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29316024/fully-automated-segmentation-of-the-left-ventricle-in-cine-cardiac-mri-using-neural-network-regression
#6
Li Kuo Tan, Robert A McLaughlin, Einly Lim, Yang Faridah Abdul Aziz, Yih Miin Liew
BACKGROUND: Left ventricle (LV) structure and functions are the primary assessment performed in most clinical cardiac MRI protocols. Fully automated LV segmentation might improve the efficiency and reproducibility of clinical assessment. PURPOSE: To develop and validate a fully automated neural network regression-based algorithm for segmentation of the LV in cardiac MRI, with full coverage from apex to base across all cardiac phases, utilizing both short axis (SA) and long axis (LA) scans...
January 9, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29313191/paths-to-parenthood-among-self-identified-bisexual-individuals-in-the-united-states
#7
Jessamyn Bowling, Brian Dodge, Elizabeth Bartelt, Megan Simmons, J Dennis Fortenberry
Bisexual parents have been notably absent from prior research on parenting, despite comprising the largest proportion of parents among "lesbian, gay, and bisexual" (LGB) individuals. Indeed, recent national probability data indicate that young bisexual women are more likely than their heterosexual counterparts to report having at least one child. Intentions to have children, patterns of family planning and contraception use, and related issues have important implications for health and healthcare-related decisions and priorities among bisexual parents...
January 8, 2018: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/29305284/evaluation-of-hospital-grade-disinfectants-on-viral-deposition-on-surfaces-after-toilet-flushing
#8
Hannah P Sassi, Kelly A Reynolds, Ian L Pepper, Charles P Gerba
BACKGROUND: Past studies have shown that infectious aerosols created during toilet flushing result in surface contamination of the restroom. The goals of this study were to quantify viral contamination of surfaces in restrooms after flushing and the impact of disinfectants added to the toilet bowl prior to flushing on reducing surface contamination. METHODS: The degree of contamination of surfaces in the restroom was assessed with and without the addition of coliphage MS2 to the toilet bowl before flushing...
January 2, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29303681/patient-experiences-with-influenza-immunizations-administered-by-pharmacists
#9
Jennifer E Isenor, Amy C Wagg, Susan K Bowles
Influenza vaccination is the most effective way to reduce influenza infection and related complications. Unfortunately, vaccination coverage remains suboptimal. The addition of pharmacists as immunizers may assist in improving vaccine coverage. The experiences of patients who have received influenza vaccines from pharmacists is an important consideration for jurisdictions considering the addition of pharmacists as immunizers. We describe the reported experiences of recipients of influenza vaccinations by pharmacists in the community pharmacy setting in Nova Scotia, Canada...
January 5, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29303500/temperature-induced-pseudopolymorphism-of-molecular-salts-from-a-pyridyl-bis-urea-macrocycle-and-naphthalene-1-5-disulfonic-acid
#10
Bozumeh Som, Jessica R Shue, Mark D Smith, Linda S Shimizu
Molecular salts, often observed as cocrystals, play an important role in the fields of pharmaceutics and materials science, where salt formation is used to tune the properties of active pharmaceutical ingredients (APIs) and improve the stability of solid-state materials. Salt formation via a proton-transfer reaction typically alters hydrogen-bonding motifs and influences supramolecular assembly patterns. We report here the molecular salts formed by the pyridyl bis-urea macrocycle 3,5,13,15,21,22-hexaazatricyclo[15...
January 1, 2018: Acta Crystallographica. Section C, Structural Chemistry
https://www.readbyqxmd.com/read/29300105/misspecification-in-latent-change-score-models-consequences-for-parameter-estimation-model-evaluation-and-predicting-change
#11
D Angus Clark, Amy K Nuttall, Ryan P Bowles
Latent change score models (LCS) are conceptually powerful tools for analyzing longitudinal data (McArdle & Hamagami, 2001). However, applications of these models typically include constraints on key parameters over time. Although practically useful, strict invariance over time in these parameters is unlikely in real data. This study investigates the robustness of LCS when invariance over time is incorrectly imposed on key change-related parameters. Monte Carlo simulation methods were used to explore the impact of misspecification on parameter estimation, predicted trajectories of change, and model fit in the dual change score model, the foundational LCS...
January 4, 2018: Multivariate Behavioral Research
https://www.readbyqxmd.com/read/29299472/does-a-simple-syringe-applicator-enhance-bone-cement-set-up-time-in-knee-arthroplasty
#12
Nipun Sodhi, Sarah E Dalton, Anton Khlopas, Assem A Sultan, Gannon L Curtis, Matthew A Harb, Qais Naziri, Jared M Newman, John W Barrington, Michael A Mont
Background: The time required for polymethylmethacrylate (PMMA) cement curing or hardening can be modified by a number of variables including the mixing technique, and the temperature and pressure at which the process is taking place. Therefore, the purpose of this study was to evaluate two different methods of PMMA application in terms of set up time. Specifically, we (I) compared the PMMA set up time of cement that remained in the mixing bowl to cement that was placed in a syringe and (II) extrapolated the associated annual cost difference on the national and individual surgeon levels...
December 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29297713/character-apps-for-children-s-snacks-effects-of-character-awareness-on-snack-selection-and-consumption-patterns
#13
Marisa M Putnam, Caroline E Cotto, Sandra L Calvert
OBJECTIVE: Media characters are used to market snacks that are typically of poor nutritional value, which has been linked to childhood obesity. This study examines whether children's snack selections and consumption patterns are influenced by an app depicting a popular children's media character, as well as the role that children's awareness of the character plays. The results can increase our understanding of how to encourage healthier snack selection and consumption in newer game-based marketing venues, such as apps...
January 3, 2018: Games for Health
https://www.readbyqxmd.com/read/29289165/the-oxford-space-environment-goniometer-a-new-experimental-setup-for-making-directional-emissivity-measurements-under-a-simulated-space-environment
#14
T J Warren, N E Bowles, K Donaldson Hanna, I R Thomas
Measurements of the light scattering behaviour of the regoliths of airless bodies via remote sensing techniques in the Solar System, across wavelengths from the visible to the far infrared, are essential in understanding their surface properties. A key parameter is knowledge of the angular behaviour of scattered light, usually represented mathematically by a phase function. The phase function is believed to be dependent on many factors including the following: surface composition, surface roughness across all length scales, and the wavelength of radiation...
December 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/29289080/characteristics-of-seismic-survey-pulses-and-the-ambient-soundscape-in-baffin-bay-and-melville-bay-west-greenland
#15
S Bruce Martin, Marie-Noël R Matthews, Jeff T MacDonnell, Koen Bröker
In 2012 a seismic survey campaign involving four vessels was conducted in Baffin Bay, West Greenland. Long-distance (150 km) pre-survey acoustic modeling was performed in accordance with regulatory requirements. Four acoustic recorders, three with hydrophones at 100, 200, and 400 m depths, measured ambient and anthropogenic sound during the survey. Additional recordings without the surveys were made from September 2013 to September 2014. The results show that (1) the soundscape of Baffin Bay is typical for open ocean environments and Melville Bay's soundscape is dominated by glacial ice noise; (2) there are distinct multipath arrivals of seismic pulses 40 km from the array; (3) seismic sound levels vary little as a function of depth; (4) high fidelity pre-survey acoustic propagation modeling produced reliable results; (5) the daily SEL did not exceed regulatory thresholds and were different using Southall, Bowles, Ellison, Finneran, Gentry, Greene, Kastak, Ketten, Miller, Nachtigall, Richardson, Thomas, and Tyack [(2007) Aquat...
December 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/29288423/proposal-of-a-classification-system-for-the-assessment-and-treatment-of-prominent-ear-deformity
#16
Youngdae Lee, Young Seok Kim, Won Jai Lee, Dong Kyun Rha, Jiye Kim
BACKGROUND: Prominent ear is the most common external ear deformity. To comprehensively treat prominent ear deformity, adequate comprehension of its pathophysiology is crucial. In this article, we analyze cases of prominent ear and suggest a simple classification system and treatment algorithm according to pathophysiology. METHODS: We retrospectively reviewed a total of 205 Northeast Asian patients' clinical data who underwent an operation for prominent ear deformity...
December 29, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29281905/identifying-factors-associated-with-mobility-decline-among-hospitalized-older-adults
#17
Jo-Ana D Chase, Alicia Lozano, Alexandra Hanlon, Kathryn H Bowles
Hospitalization can negatively affect mobility among older adults. Early detection of older patients most at risk for mobility decline can lead to early intervention and prevention of mobility loss. This study's purpose was to identify factors from the International Classification of Functioning, Disability, and Health associated with mobility decline among hospitalized elders. We conducted a secondary analysis of data from 959 hospitalized adults age 65 and older. We estimated the effects of health conditions and environmental and personal factors on mobility decline using logistic regression...
February 2018: Clinical Nursing Research
https://www.readbyqxmd.com/read/29280478/convergent-evolution-of-floral-shape-tied-to-pollinator-shifts-in-iochrominae-solanaceae
#18
Stacey D Smith, Ricardo Kriebel
Flower form is one of many floral features thought to be shaped by pollinator-mediated selection. Although the drivers of variation in flower shape have often been examined in microevolutionary studies, relatively few have tested the relationship between shape evolution and shifts in pollination system across clades. In the present study, we use morphometric approaches to quantify shape variation across the Andean clade Iochrominae and estimate the relationship between changes in shape and shifts in pollination system using phylogenetic comparative methods...
December 27, 2017: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/29280250/a-quintuple-6-helicene-with-a-corannulene-core-as-a-c5-symmetric-propeller-shaped-%C3%AF-system
#19
Kenta Kato, Yasutomo Segawa, Lawrence T Scott, Kenichiro Itami
The synthesis and structural analysis of a quintuple [6]helicene with a corannulene core (1) is reported. Compound 1 was synthesized from corannulene in three steps including a five-fold C-H/C-Cl intramolecular coupling reaction. X-ray crystallographic analysis of 1 revealed a C5-symmetric propeller-shaped structure and one-dimensional alignment in the solid state. The enantiomers of 1 were successfully separated by HPLC, and the chirality of the two fractions was identified by CD spectroscopy. A kinetic study yielded a racemization barrier of 33...
December 26, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/29275381/maxillary-chondrosarcoma-mimicking-torus-palatinus
#20
Marina Brimioulle, Philippe Frederick Bowles, Andrew Pelser
No abstract text is available yet for this article.
December 22, 2017: BMJ Case Reports
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