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https://www.readbyqxmd.com/read/28420255/chemical-and-common-burns-in-children
#1
Shan Yin
Burns are a common cause of preventable morbidity and mortality in children. Thermal and chemical burns are the most common types of burns. Their clinical appearance can be similar and the treatment is largely similar. Thermal burns in children occur primarily after exposure to a hot surface or liquid, or contact with fire. Burns are typically classified based on the depth and total body surface area, and the severity and onset of the burn can also depend on the temperature and duration of contact. Chemical burns are caused by chemicals-most commonly acids and alkalis-that can damage the skin on contact...
May 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28420055/perceived-stress-and-reported-cognitive-symptoms-among-georgia-patients-with-systemic-lupus-erythematosus
#2
L Plantinga, S S Lim, C B Bowling, C Drenkard
Objective To examine associations of perceived stress with cognitive symptoms among adults with systemic lupus erythematosus (SLE). Methods Among 777 adult (≥18 years) SLE patients, the association of Perceived Stress Scale (PSS) scores with two self-reported cognitive symptoms was examined: forgetfulness (severe/moderate vs. mild/none; from the Systemic Lupus Activity Questionnaire) and difficulty concentrating (all/most vs. some/little/none of the time; from the Lupus Impact Tracker). The study used multivariable logistic regression to estimate the odds ratios (ORs) per minimal important difference (MID = 0...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28419028/physical-activity-assessment-with-the-actigraph-gt3x-and-doubly-labeled-water
#3
Andrea K Chomistek, Changzheng Yuan, Charles E Matthews, Richard P Troiano, Heather R Bowles, Jennifer Rood, Junaidah B Barnett, Walter C Willett, Eric B Rimm, David R Bassett
PURPOSE: To compare the degree to which four accelerometer metrics-total activity counts per day (TAC/d), steps per day (steps/d), physical activity energy expenditure (PAEE, kcal/kg/day), and moderate- to vigorous-intensity physical activity (MVPA, min/d)- were correlated with PAEE measured by doubly-labeled water (DLW). Additionally, accelerometer metrics based on vertical axis counts and triaxial counts were compared. METHODS: This analysis included 684 women and 611 men aged 43 - 83 years...
April 18, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28409631/entropy-driven-ball-in-bowl-assembly-of-fullerene-and-geodesic-phenylene-bowl
#4
Koki Ikemoto, Ryo Kobayashi, Sota Sato, Hiroyuki Isobe
Complexation of C60 at a conical region of a nanometer-sized geodesic phenylene bowl has been demonstrated. Proton NMR spectroscopy showed formation of a 1:1 complex that was driven by entropy gains for the assembly. Crystallographic analyses revealed its unique ball-in-bowl structure, and the presence of smoothly curved surfaces was unveiled at their interfaces.
April 14, 2017: Organic Letters
https://www.readbyqxmd.com/read/28402015/synthesis-and-bowl-in-bowl-assembly-of-a-geodesic-phenylene-bowl
#5
Koki Ikemoto, Ryo Kobayashi, Sota Sato, Hiroyuki Isobe
A phenylene multiring with a corannulenoidal skeleton was synthesized. Geodesic constraints over 20 phenylene panels resulted in its nanometer-sized, bowl-shaped molecular structure, which was unequivocally revealed by crystallographic analysis. The crystal structure also showed the presence of a bowl-in-bowl dimeric assembly, which was driven by entropic factors in solution.
April 12, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28399830/electromagnetic-navigation-bronchoscopy-to-access-lung-lesions-in-1-000-subjects-first-results-of-the-prospective-multicenter-navigate-study
#6
Sandeep J Khandhar, Mark R Bowling, Javier Flandes, Thomas R Gildea, Kristin L Hood, William S Krimsky, Douglas J Minnich, Septimiu D Murgu, Michael Pritchett, Eric M Toloza, Momen M Wahidi, Jennifer J Wolvers, Erik E Folch
BACKGROUND: Electromagnetic navigation bronchoscopy (ENB) is an image-guided, minimally invasive approach that uses a flexible catheter to access pulmonary lesions. METHODS: NAVIGATE is a prospective, multicenter study of the superDimension™ navigation system. A prespecified 1-month interim analysis of the first 1,000 primary cohort subjects enrolled at 29 sites in the United States and Europe is described. Enrollment and 24-month follow-up are ongoing. RESULTS: ENB index procedures were conducted for lung lesion biopsy (n = 964), fiducial marker placement (n = 210), pleural dye marking (n = 17), and/or lymph node biopsy (n = 334; primarily endobronchial ultrasound-guided)...
April 11, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28399767/when-work-triggers-painful-emotions
#7
Mandy Day-Calder
I have vivid memories of nursing an elderly man whose wife visited every day and kept him well supplied with pristine pyjamas. I was bowled over by the aroma of his freshly laundered nightclothes. The smell instantly took me back to my childhood and evoked such strong, loving memories of my mum.
April 12, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28394894/tissue-specific-enhancer-repression-through-molecular-integration-of-cell-signaling-inputs
#8
Luis Humberto Mojica-Vázquez, Mikhail H Benetah, Aissette Baanannou, Sandra Bernat-Fabre, Bart Deplancke, David L Cribbs, Henri-Marc Bourbon, Muriel Boube
Drosophila leg morphogenesis occurs under the control of a relatively well-known genetic cascade, which mobilizes both cell signaling pathways and tissue-specific transcription factors. However, their cross-regulatory interactions, deployed to refine leg patterning, remain poorly characterized at the gene expression level. Within the genetically interacting landscape that governs limb development, the bric-à-brac2 (bab2) gene is required for distal leg segmentation. We have previously shown that the Distal-less (Dll) homeodomain and Rotund (Rn) zinc-finger activating transcription factors control limb-specific bab2 expression by binding directly a single critical leg/antennal enhancer (LAE) within the bric-à-brac locus...
April 10, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28394876/scleral-lens-prescription-and-management-practices-the-scope-study
#9
Jennifer Harthan, Cherie B Nau, Joseph Barr, Amy Nau, Ellen Shorter, Nicolette T Chimato, David O Hodge, Muriel M Schornack
OBJECTIVES: To assess current scleral lens prescription and management practices by conducting an international online survey of eye care providers. METHODS: The SCOPE (Scleral Lenses in Current Ophthalmic Practice: an Evaluation) study group designed and administered an online survey regarding current scleral lens prescription and management practices. The survey was open from January 15 to March 31, 2015, and generated 723 responses from individuals who had fit at least 5 patients with scleral lenses...
April 6, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28393012/the-effect-of-repetitive-subconcussive-collisions-on-brain-integrity-in-collegiate-football-players-over-a-single-football-season-a-multi-modal-neuroimaging-study
#10
Semyon M Slobounov, Alexa Walter, Hans C Breiter, David C Zhu, Xiaoxiao Bai, Tim Bream, Peter Seidenberg, Xianglun Mao, Brian Johnson, Thomas M Talavage
The cumulative effect of repetitive subconcussive collisions on the structural and functional integrity of the brain remains largely unknown. Athletes in collision sports, like football, experience a large number of impacts across a single season of play. The majority of these impacts, however, are generally overlooked, and their long-term consequences remain poorly understood. This study sought to examine the effects of repetitive collisions across a single competitive season in NCAA Football Bowl Subdivision athletes using advanced neuroimaging approaches...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28390609/peri-operative-management-of-high-risk-paediatric-adenotonsillectomy-patients-a-survey-of-35-uk-tertiary-referral-centres
#11
Ryan Chin Taw Cheong, Philippe Bowles, Andrew Moore, Simon Watts
INTRODUCTION: Peri-operative management of high-risk paediatric patients undergoing adenotonsillectomy for treatment of obstructive sleep apnoea varies between tertiary referral hospitals. 'Day of surgery cancellation' (DoSC) rates of up to 11% have been reported due to pre-booked critical care being unavailable on the day of surgery as a result of competing needs from other hospital departments. We report the results of a survey of peri-operative management in UK tertiary care centres of high-risk paediatric patients undergoing adenotonsillectomy for obstructive sleep apnoea (OSA)...
May 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28389529/older-patients-perspectives-on-managing-complexity-in-ckd-self-management
#12
C Barrett Bowling, Ann E Vandenberg, Lawrence S Phillips, William M McClellan, Theodore M Johnson, Katharina V Echt
BACKGROUND AND OBJECTIVES: Patients with CKD are asked to perform self-management tasks including dietary changes, adhering to medications, avoiding nephrotoxic drugs, and self-monitoring hypertension and diabetes. Given the effect of aging on functional capacity, self-management may be especially challenging for older patients. However, little is known about the specific challenges older adults face maintaining CKD self-management regimens. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted an exploratory qualitative study designed to understand the relationship among factors facilitating or impeding CKD self-management in older adults...
April 3, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28389138/preschool-children-s-sensitivity-to-teacher-served-portion-size-is-linked-to-age-related-differences-in-leftovers
#13
Keri McCrickerd, Claudia Leong, Ciaran G Forde
A strong predictor of children's food intake at a meal is the amount they are served, and with a high percentage children attending preschool, there is a need to consider the relationship between portion size and intake in this context. In a two-part repeated measures study we investigated whether the portions teachers serve to children i) differ from those children would serve themselves and ii) impact food intake at a local preschool in Singapore. Part 1 (n = 37, 20 boys, 3.0-6.8 years) compared the quantity of food served, consumed and leftover across three serving methods: 'regular' teacher-serving; child self-served portions; and a deliberately large portion served by the teacher (150% of each child's average previous gram intake)...
April 5, 2017: Appetite
https://www.readbyqxmd.com/read/28387601/the-application-of-the-index-of-orthognathic-functional-treatment-need-ioftn-service-evaluation-and-impact
#14
Eamon Howard-Bowles, John Ho-A-Yun, Aman Ulhaq, Niall J P McGuinness
OBJECTIVES: (1) To undertake a service evaluation of the Index of Orthognathic Functional Treatment Need (IOFTN). (2) To determine its suitability to replace the Index of Orthodontic Treatment Need (IOTN) in the assessment of patients with dentofacial deformity. DESIGN: Laboratory- and questionnaire-based study. SETTING: UK hospital-based orthodontic department. METHODS: Cohen's Kappa was used to assess inter- and intra-operator reliability for the IOTN and the IOFTN against 30 orthognathic patients' models scored to a 'gold standard'...
April 7, 2017: Journal of Orthodontics
https://www.readbyqxmd.com/read/28380701/falls-risks-and-prevention-behaviors-among-community-dwelling-homebound-and-non-homebound-older-adults
#15
Carri Casteel, Jennifer Jones, Paula Gildner, James M Bowling, Susan J Blalock
The objectives were to examine falls risk factors to determine how the magnitude of risk may differ between homebound and non-homebound older adults, and to describe falls prevention behaviors and participation in falls prevention education. A cross-sectional survey was conducted with convenience samples of community-dwelling older adults recruited through Meals on Wheels programs (homebound, n = 80) and senior centers (non-homebound, n = 84) in North Carolina. Data were collected during home visits and included an interview and medication inventory...
October 1, 2016: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
https://www.readbyqxmd.com/read/28379616/from-fish-bowl-to-bedside-the-power-of-zebrafish-to-unravel-melanoma-pathogenesis-and-discover-new-therapeutics
#16
REVIEW
Ellen van Rooijen, Maurizio Fazio, Leonard I Zon
Melanoma is the most aggressive and deadliest form of skin cancer. A detailed knowledge of the cellular, molecular and genetic events underlying melanoma progression is highly relevant to diagnosis, prognosis and risk stratification, and the development of new therapies. In the last decade, zebrafish have emerged as a valuable model system for the study of melanoma. Pathway conservation, coupled with the availability of robust genetic, transgenic and chemical tools, has made the zebrafish a powerful model for identifying novel disease genes, visualizing cancer initiation, interrogating tumor-microenvironment interactions and discovering new therapeutics that regulate melanocyte and melanoma development...
April 5, 2017: Pigment Cell & Melanoma Research
https://www.readbyqxmd.com/read/28376943/is-there-a-correlation-between-infection-control-performance-and-other-hospital-quality-measures
#17
Lyndsay M O'Hara, Daniel J Morgan, Lisa Pineles, Shanshan Li, Carol Sulis, Jason Bowling, Marci Drees, Jesse T Jacob, Deverick J Anderson, David K Warren, Anthony D Harris
Quality measures are increasingly reported by hospitals to the Centers for Medicare and Medicaid Services (CMS), yet there may be tradeoffs in performance between infection control (IC) and other quality measures. Hospitals that performed best on IC measures did not perform well on most CMS non-IC quality measures. Infect Control Hosp Epidemiol 2017;1-4.
April 5, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28370999/divergent-synthesis-of-heteroatom-centered-4-8-12-triazatriangulenes
#18
Soichiro Nakatsuka, Hajime Gotoh, Keisuke Kinoshita, Nobuhiro Yasuda, Takuji Hatakeyama
The increasing attention devoted to triangulenes and their heteroatom derivatives inspired us to explore a divergent synthesis of heteroatom-centered 4,8,12-triazatriangulenes, which involved the preparation of a nitrogen-containing macrocyclic precursor and subsequent central heteroatom introduction by electrophilic C-Li and C-H substitution. The boron-centered triangulene has a planar structure unlike the bowl-shaped phosphorus- and silicon-centered triangulenes. The described synthetic procedure can be used to fabricate a broad range of attractive functional materials, for example, for organic light-emitting diodes, based on heteroatom-centered triangulenes...
March 29, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28364328/use-of-three-monitoring-approaches-to-manage-a-major-chrysosporum-ovalisporum-bloom-in-the-murray-river-australia-2016
#19
Adam Crawford, Jon Holliday, Chester Merrick, John Brayan, Mark van Asten, Lee Bowling
An unusual bloom of Chrysosporum ovalisporum (basionym Aphanizomenon ovalisporum) occurred for the first time in the Murray River and distributary rivers in New South Wales, Australia, from mid-February to early June 2016. At its greatest extent, it contaminated a combined river length of ca. 2360 km. Chrysosporum ovalisporum usually comprised >99% of the total bloom biovolume at most locations sampled, which at times exceeded 40 mm(3) l(-1). The origins of the bloom were most likely reservoirs on the upper Murray River, with cyanobacterial-infested water released from them contaminating the river systems downstream...
April 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28360239/instruments-measuring-the-disease-specific-quality-of-life-of-family-carers-of-people-with-neurodegenerative-diseases-a-systematic-review
#20
Thomas E Page, Nicolas Farina, Anna Brown, Stephanie Daley, Ann Bowling, Thurstine Basset, Gill Livingston, Martin Knapp, Joanna Murray, Sube Banerjee
OBJECTIVE: Neurodegenerative diseases, such as dementia, have a profound impact on those with the conditions and their family carers. Consequently, the accurate measurement of family carers' quality of life (QOL) is important. Generic measures may miss key elements of the impact of these conditions, so using disease-specific instruments has been advocated. This systematic review aimed to identify and examine the psychometric properties of disease-specific outcome measures of QOL of family carers of people with neurodegenerative diseases (Alzheimer's disease and other dementias; Huntington's disease; Parkinson's disease; multiple sclerosis; and motor neuron disease)...
March 29, 2017: BMJ Open
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