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J E Isenor, N T Edwards, T A Alia, K L Slayter, D M MacDougall, S A McNeil, S K Bowles
BACKGROUND: Underutilization of vaccination programs remains a significant public health concern. Pharmacists serve as educators, facilitators, and in some jurisdictions, as administrators of vaccines. Though pharmacists have been involved with immunizations in various ways for many years, there has yet to be a systematic review assessing the impact of pharmacists as immunizers in these three roles. OBJECTIVE: To complete a systematic review of the literature on the impact of pharmacists as educators, facilitators, and administrators of vaccines on immunization rates...
October 17, 2016: Vaccine
Marisa Hoeschele, Daniel L Bowling
A variety of parrot species have recently gained attention as members of a small group of non-human animals that are capable of coordinating their movements in time with a rhythmic pulse. This capacity is highly developed in humans, who display unparalleled sensitivity to musical beats and appear to prefer rhythmically organized sounds in their music. Do parrots also exhibit a preference for rhythmic over arrhythmic sounds? Here, we presented humans and budgerigars (Melopsittacus undulatus) - a small parrot species that have been shown to be able to align movements with a beat - with rhythmic and arrhythmic sound patterns in an acoustic place preference paradigm...
2016: Frontiers in Psychology
Nivan Weerakkody, Trevor Allen
The impact that muscle fatigue and taping have on proprioception in an applied sporting context remains unclear. The purpose of this study was to investigate disturbances in position sense at the shoulder joint, and asses the effectiveness of adhesive tape in preventing injury and improving performance, after a bout of cricket fast bowling. Among amateur cricket players (N = 14), shoulder position sense, maximum voluntary contraction (MVC) force and bowling accuracy was assessed before and immediately after a fatiguing exercise bout of fast bowling...
October 18, 2016: Journal of Sports Sciences
Seong-Tshool Hong
The human intestine contains a massive and complex microbial community called gut microbiota. A typical human carries 100 trillion microbes in his/her body which is 10 times greater than the number of their host cells, i.e. whole number of human cells. A combined microbial genome constituting gut microbiota is well excess our own human genome. The microbial composition of gut microbiotata and its role on diseases became a booming area of research, presenting a new paradigm of opportunities for modern medicines...
September 2016: Journal of Hypertension
Kristi Reynolds, Daichi Shimbo, C Barrett Bowling, Luqin Deng, Adam Bress, John Sim, Paul Muntner
OBJECTIVE: To identify risk factors for serious fall injuries following initiation of antihypertensive medication among older adults. DESIGN AND METHOD: We conducted a retrospective cohort study using a 5% random sample of people with Medicare health insurance, a government program for older US adults. The analysis was restricted to patients with a diagnosis of hypertension who initiated antihypertensive medication between 2007 and 2011. Initiation was defined by the first antihypertensive medication fill in this time period preceded by 365 days with no antihypertensive medication fills...
September 2016: Journal of Hypertension
Steven Landers, Elizabeth Madigan, Bruce Leff, Robert J Rosati, Barbara A McCann, Rodney Hornbake, Richard MacMillan, Kate Jones, Kathryn Bowles, Dawn Dowding, Teresa Lee, Tracey Moorhead, Sally Rodriguez, Erica Breese
The Future of Home Health project sought to support transformation of home health and home-based care to meet the needs of patients in the evolving U.S. health care system. Interviews with key thought leaders and stakeholders resulted in key themes about the future of home health care. By synthesizing this qualitative research, a literature review, case studies, and the themes from a 2014 Institute of Medicine and National Research Council workshop on "The Future of Home Health Care," the authors articulate a vision for home-based care and recommend a bold framework for the Medicare-certified home health agency of the future...
November 2016: Home Health Care Management & Practice
Anne C Grunseit, Samantha Rowbotham, Melanie Pescud, Devon Indig, Sonia Wutzke
Issue addressed: The Australian National Partnership Agreement on Preventive Health (NPAPH) charged states and territories with the development and implementation of the Healthy Workers Initiative (HWI) to improve workplace health promotion. Most evaluation efforts focus on the setting (micro) level. In the present study the HWI at the meso-level (state program development) was examined to understand how jurisdictions navigated theoretical, practical, and political priorities to develop their programs, and the programmatic choices that support or hinder perceived success...
October 13, 2016: Health Promotion Journal of Australia
Allison R Heid, Seran Schug, Francine P Cartwright, Rachel Pruchno
OBJECTIVE: Individuals exposed to natural disasters are at risk for negative physical and psychological outcomes. Older adults may be particularly vulnerable; however, social support can act as a resource to help individuals respond to severe stressors. This study explored the challenges older people faced before, during, and after Hurricane Sandy in October 2012 and the people they turned to for support. METHODS: Semi-structured interviews were conducted with 20 older adults in New Jersey drawn from the ORANJ BOWL (Ongoing Research on Aging in New Jersey - Bettering Opportunities for Wellness in Life) research panel, who experienced high levels of primary home damage during Hurricane Sandy...
October 14, 2016: Disaster Medicine and Public Health Preparedness
Kathryn R Bowles, Simon P Brooks, Alis C Hughes, Stephen B Dunnett, Lesley Jones
[This corrects the article DOI: 10.1371/journal.pone.0144864.].
2016: PloS One
Cassy M Spiller, Guillaume Burnet, Josephine Bowles
The fetal gonad contains a great variety of differentiating cell populations, of which germ cells make up a small percentage. In order to study germ cell-specific gene and protein expression, as well as determine direct effects of signaling molecules, it is necessary to prepare enriched populations of germ cells and maintain them in culture for several hours to multiple days. The protocols in this chapter are designed to provide a guide for the isolation or enrichment of mouse primordial germ cells (from 9...
2017: Methods in Molecular Biology
C Barrett Bowling, Laura Plantinga, Rasheeda K Hall, Anna Mirk, Rebecca Zhang, Nancy Kutner
BACKGROUND AND OBJECTIVES: The majority of older adults who initiate dialysis do so during a hospitalization, and these patients may require post-acute skilled nursing facility (SNF) care. For these patients, a focus on nondisease-specific problems, including cognitive impairment, depressive symptoms, exhaustion, falls, impaired mobility, and polypharmacy, may be more relevant to outcomes than the traditional disease-oriented approach. However, the association of the burden of nondisease-specific problems with mortality, transition to long-term care (LTC), and functional impairment among older adults receiving SNF care after dialysis initiation has not been studied...
October 12, 2016: Clinical Journal of the American Society of Nephrology: CJASN
Stephanie Höhn, Armin Hallmann
BACKGROUND: The multicellular volvocine alga Pleodorina is intermediate in organismal complexity between its unicellular relative, Chlamydomonas, and its multicellular relative, Volvox, which shows complete division of labor between different cell types. The volvocine green microalgae form a group of genera closely related to the genus Volvox within the order Volvocales (Chlorophyta). Embryos of multicellular volvocine algae consist of a cellular monolayer that, depending on the species, is either bowl-shaped or comprises a sphere...
October 13, 2016: BMC Developmental Biology
Annie C Bowles, Amy L Strong, Rachel M Wise, Robert C Thomas, Brittany Y Gerstein, Maria F Dutreil, Ryan S Hunter, Jeffrey M Gimble, Bruce A Bunnell
Multiple sclerosis (MS) is a common neurodegenerative disease and remains an unmet clinical challenge. In MS, an autoimmune response leads to immune cell infiltration, inflammation, demyelination, and lesions in central nervous system (CNS) tissues resulting in tremors, fatigue, and progressive loss of motor function. These pathologic hallmarks are effectively reproduced in the murine experimental autoimmune encephalomyelitis (EAE) model. The stromal vascular fraction (SVF) of adipose tissue is composed of adipose-derived stromal/stem cells (ASC), adipocytes, and various leukocytes...
October 12, 2016: Stem Cells
William A Stokes, Bernard L Jones, Shilpa Bhatia, Ayman J Oweida, Daniel W Bowles, David Raben, Julie A Goddard, Jessica D McDermott, Sana D Karam
BACKGROUND: Although laryngectomy is the treatment of choice for patients with T4 larynx cancer, many patients are unable or unwilling to undergo laryngectomy and instead pursue larynx-preservation strategies combining radiotherapy (RT) and chemotherapy. Herein, the authors analyzed the National Cancer Data Base to evaluate overall survival (OS) between patients treated with surgical and organ-preserving modalities. METHODS: The National Cancer Data Base was queried for patients diagnosed from 2004 through 2012 with T4M0 laryngeal cancer who underwent either laryngectomy (surgery) with adjuvant RT (SRT), chemotherapy starting concurrently within 7 days of RT (CCRT), or multiagent induction chemotherapy starting 43 to 98 days before RT (ICRT)...
October 11, 2016: Cancer
Andrea Necchi, Guru Sonpavde, Salvatore Lo Vullo, Daniele Giardiello, Aristotelis Bamias, Simon J Crabb, Lauren C Harshman, Joaquim Bellmunt, Ugo De Giorgi, Cora N Sternberg, Linda Cerbone, Sylvain Ladoire, Yu-Ning Wong, Evan Y Yu, Simon Chowdhury, Gunter Niegisch, Sandy Srinivas, Ulka N Vaishampayan, Sumanta K Pal, Neeraj Agarwal, Ajjai Alva, Jack Baniel, Ali-Reza Golshayan, Rafael Morales-Barrera, Daniel W Bowles, Matthew I Milowsky, Christine Theodore, Dominik R Berthold, Gedske Daugaard, Srikala S Sridhar, Thomas Powles, Jonathan E Rosenberg, Matthew D Galsky, Luigi Mariani
BACKGROUND: The available prognostic models for overall survival (OS) in patients with metastatic urothelial carcinoma (UC) have been derived from clinical trial populations of cisplatin-treated patients. OBJECTIVE: To develop a new model based on real-world patients. DESIGN, SETTING, AND PARTICIPANTS: Individual patient-level data from 29 centers were collected, including metastatic UC and first-line cisplatin- or carboplatin-based chemotherapy administered between January 2006 and January 2011...
October 8, 2016: European Urology
Chang-Hyun Lee, In Seok Han, Ji Yeoun Lee, Ji Hoon Phi, Seung-Ki Kim, Young-Eun Kim, Kyu-Chang Wang
OBJECTIVE: Although arachnoid cysts (ACs) are observed in various locations, only sylvian ACs are mainly regarded to be associated with bleeding. The reason for this selective association of sylvian ACs with bleeding is not understood well. This study is to investigate the effect of the location and shape of ACs on the risk of bleeding. METHODS: A developed finite element model of the head/brain was modified for models of sylvian, suprasellar, and posterior fossa ACs...
October 7, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Lin Xiong, Shi-Zhang Qiao
Mesoporous organosilica nanoparticles with a novel bowl-like morphology were synthesized. These nano-bowls possess uniform particle sizes around 180 nm and open cavities around 140 nm, which lead to higher loading capability for plasmid DNA than traditional silica-based nanoparticles. In vitro DNA transfection using these nano-bowls is demonstrated.
October 14, 2016: Nanoscale
Shitao Wang, Tomohisa Sawada, Makoto Fujita
A new M20L8 coordination capsule was synthesized. Owing to the structural flexibility and dynamic properties, the capsule showed wide scope for guest encapsulation. Furthermore, unique capsule-bowl conversion occurred upon a large guest encapsulation or a guest reaction.
September 22, 2016: Chemical Communications: Chem Comm
Janelle J Montroy, Ryan P Bowles, Lori E Skibbe, Megan M McClelland, Frederick J Morrison
The development of early childhood self-regulation is often considered an early life marker for later life successes. Yet little longitudinal research has evaluated whether there are different trajectories of self-regulation development across children. This study investigates the development of behavioral self-regulation between the ages of 3 and 7 years, with a direct focus on possible heterogeneity in the developmental trajectories, and a set of potential indicators that distinguish unique behavioral self-regulation trajectories...
October 6, 2016: Developmental Psychology
Samuel Lampart, Loïc M Roch, Amit K Dutta, Yujia Wang, Rangana Warshamanage, Aaron D Finke, Anthony Linden, Kim K Baldridge, Jay S Siegel
Pentaindenocorannulene (C50 H20  , 1), a deep bowl polynuclear aromatic hydrocarbon, accepts 4 electrons, crystallizes in columnar bowl-in-bowl assemblies and forms a nested C60 @12 complex. Spectra, structures and computations are presented.
October 6, 2016: Angewandte Chemie
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