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https://www.readbyqxmd.com/read/28340446/mental-health-and-behavioral-weight-loss-24-month-outcomes-in-veterans
#1
Carol A Janney, Robin M Masheb, Lesley D Lutes, Robert G Holleman, Hyungjin Myra Kim, Leah R Gillon, Laura J Damschroder, Caroline R Richardson
BACKGROUND: Individuals with mental health (MH) disorders have an increased risk of being overweight/obese; however research on behavioral weight loss interventions has been limited. A priori hypothesis was that Veterans with serious mental illness (SMI) and/or affective disorders (AD) would lose significantly less weight and have a different pattern of weight loss than Veterans without these diagnoses. METHODS: Secondary data analysis of ASPIRE-VA study, three-arm randomized, effectiveness weight loss trial among Veterans (n=409) categorized by MH diagnoses: 1) SMI, 2) AD without SMI, or 3) No SMI/No AD...
March 11, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28330732/racial-ethnic-differences-in-weight-loss-strategies-among-us-adults-national-health-and-nutrition-examination-survey-2007-2012
#2
Becky Marquez, Rosenda Murillo
BACKGROUND: Dieting, exercising, and seeking professional help have been associated with intentional weight loss among adults. OBJECTIVE: This study examined the use of diet (eg, ate less, ate less fat, or switched to low-calorie foods), exercise, diet and exercise, and professional help (eg, weight-loss program or prescribed diet pills) for weight loss among non-Hispanic whites, Mexican Americans, and non-Hispanic blacks. DESIGN: Cross-sectional data from the 2007-2012 National Health and Nutrition Examination Survey were used...
March 15, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28325318/preparation-and-characterization-of-amine-functional-nano-hydroxyapatite-chitosan-bionanocomposite-for-bone-tissue-engineering-applications
#3
Besir Hakan Atak, Berna Buyuk, Merve Huysal, Sevim Isik, Mehmet Senel, Wolfgang Metzger, Guven Cetin
In this study, three different types of scaffolds including a uniquely modified composite scaffold - namely chitosan (CTS), nano-hydroxyapatite/chitosan composite (CTS+nHAP), and amine group (NH2) modified nano-hydroxyapatite/chitosan composite (CTS+nHAP-NH2) scaffolds - were synthesized for bone tissue engineering (BTE) purposes. As results of the study, it was found that all scaffold types were biodegradable with CTS and CTS+nHAP scaffolds losing up to 15% of their initial weight, while the CTS+nHAP-NH2 scaffold showing 10% of weight loss after six weeks of lysozyme treatment...
May 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28323533/success-in-weight-management-among-patients-with-type-2-diabetes-do-perceived-autonomy-support-autonomous-motivation-and-self-care-competence-play-a-role
#4
Anne M Koponen, Nina Simonsen, Sakari B Suominen
Based on self-determination theory (SDT), this study investigated whether the three central SDT variables-perceived autonomy support (from a physician), autonomous motivation and self-care competence-were associated with success in weight management (SWM) among primary care patients with type 2 diabetes when the effect of other important life-context factors was controlled for. Patients participated in a mail survey in 2011. Those who had tried to change their health behavior during the past two years in order to lose weight, either with or without success (n = 1433, mean age 63 years, 50% men), were included in this study...
March 21, 2017: Behavioral Medicine
https://www.readbyqxmd.com/read/28322640/experiences-of-daily-weighing-among-successful-weight-loss-individuals-during-a-12-month-weight-loss-study
#5
Y Zheng, M A Terry, C A Danford, L J Ewing, S M Sereika, R W Goode, A Mori, L E Burke
The purpose of the study was to describe participants' experience of daily weighing and to explore factors influencing adherence to daily weighing among individuals who were successful in losing weight during a behavioral weight loss intervention. Participants completed a 12-month weight loss intervention study that included daily self-weighing using a Wi-Fi scale. Individuals were eligible to participate regardless of their frequency of self-weighing. The sample ( N = 30) was predominantly female (83.3%) and White (83...
December 1, 2016: Western Journal of Nursing Research
https://www.readbyqxmd.com/read/28320766/an-adverse-lipid-profile-and-increased-levels-of-adiposity-significantly-predict-clinical-course-after-a-first-demyelinating-event
#6
Prudence Tettey, Steve Simpson, Bruce Taylor, Anne-Louise Ponsonby, Robyn M Lucas, Terence Dwyer, Karam Kostner, Ingrid Af van der Mei
OBJECTIVE: To investigate the prospective associations between adiposity and lipid-related variables and conversion to multiple sclerosis (MS), time to subsequent relapse and progression in disability. METHODS: A cohort of 279 participants with a first clinical diagnosis of central nervous system demyelination was prospectively followed to 5-year review. Height, weight, waist and hip circumference were measured, and serum samples taken for measurement of lipids and apolipoproteins...
March 20, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28318619/effect-on-the-lipid-parameters-of-an-intervention-to-reduce-weight-in-overweight-and-obese-patients
#7
M Loreto Tárraga Marcos, Josefa María Panisello Royo, Julio A Carbayo Herencia, Nuria Rosich Domenech, Josep Alins Presas, Pedro J Tárraga López
OBJECTIVE: To assess the effect on lipid parameters most associated with excess weight (triglycerides [TG], cholesterol, and high density lipoprotein [HDL-C]) of an intervention to reduce weight in overweight and obese patients. METHODS: A randomised, controlled, double blind clinical trial, with three groups, and a follow-up of 12 months. Patients included in the study were randomised into three intervention groups: Obesity motivational intervention group with previously trained nurse (G1), lower intensity consultation, non-motivational group, with digital platform support (G2), and a third group that received a recommendation to lose weight and usual follow-up (G3)...
March 16, 2017: Clínica e Investigación en Arteriosclerosis
https://www.readbyqxmd.com/read/28316325/silencing-of-the-small-gtpase-diras3-induces-cellular-senescence-in-human-white-adipose-stromal-progenitor-cells
#8
Asim Ejaz, Monika Mattesich, Werner Zwerschke
Inhibition of Akt-mTOR signaling protects from obesity and extends life span in animals. In the present study, we analyse the impact of the small GTPase, GTP-binding RAS-like 3 (DIRAS3), a recently identified weight-loss target gene, on cellular senescence in adipose stromal/progenitor cells (ASCs) derived from human subcutaneous white adipose tissue (sWAT). We demonstrate that DIRAS3 knock-down (KD) in ASCs induces activation of Akt-mTOR signaling and proliferation arrest. DIRAS3 KD ASCs lose the potential to form colonies and are negative for Ki-67...
March 17, 2017: Aging
https://www.readbyqxmd.com/read/28314557/neighborhood-socioeconomic-deprivation-and-weight-change-in-a-large-u-s-cohort
#9
Qian Xiao, David Berrigan, Sarah K Keadle, Charles E Matthews
INTRODUCTION: Both excessive weight gain and weight loss are important risk factors in the older population. Neighborhood environment may play an important role in weight change, but neighborhood effects on weight gain and weight loss have not been studied separately. This study examined the associations between neighborhood socioeconomic deprivation and excessive weight gain and weight loss. METHODS: This analysis included 153,690 men and 105,179 women (aged 51-70 years)...
March 15, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28299034/the-effect-of-a-lifestyle-modification-education-on-adiposity-measures-in-overweight-and-obese-nonalcoholic-fatty-liver-disease-patients
#10
Arman Arab, Gholamreza Askari, Parastoo Golshiri, Awat Feizi, Ali Hekmatnia, Bijan Iraj, Mojgan Nourian
BACKGROUND: Obesity is increasingly associated with nonalcoholic fatty liver disease (NAFLD) and weight loss through a combination of dietary modifications and increased physical activity is a primary goal of therapy in this disease. Therefore, this study was conducted to evaluate the effects of a lifestyle modification education on adiposity measures, physical activity, and total calorie intake in overweight and obese NAFLD patients. METHODS: During 8 weeks, 82 obese patients were randomly assigned into either an intervention group (n = 41) receiving a lifestyle modification education or to a control group (n = 41) receiving usual care...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28294635/maintenance-of-weight-loss-or-stability-in-subjects-with-obesity-a-retrospective-longitudinal-analysis-of-a-real-world-population
#11
Maral DerSarkissian, Rachel H Bhak, Joanna Huang, Sarah Buchs, Francis Vekeman, B Gabriel Smolarz, Jason Brett, Rahul Ganguly, Mei Sheng Duh
OBJECTIVES: Characterize patterns of weight change among subjects with obesity. METHODS: A retrospective observational longitudinal study of subjects with obesity was conducted using the General Electric Centricity electronic medical record database. Subjects who were ≥18 years old with BMI ≥30 kg/m(2) (first defining index BMI), had no medical conditions associated with unintentional weight loss, and had ≥4 BMI measurements/year for ≥2.5 years were included and categorized into groups (stable weight: within <5% of index BMI; modest weight loss: ≥5 to <10% of index BMI lost; moderate weight loss: ≥10 to <15% of index BMI lost; and high weight loss: ≥15% of index BMI lost) based on weight change during six months following index...
March 15, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28292205/not-taking-the-easy-way-out-reframing-bariatric-surgery-from-low-effort-weight-loss-to-hard-work
#12
Sarah Trainer, Alexandra Brewis, Amber Wutich
Cultural notions equating greater morality and virtue with hard work and productive output are deeply embedded in American value systems. This is exemplified in how people understand and execute personal body projects, including efforts to become slim. Bariatric surgery is commonly viewed as a 'low-effort' means of losing weight, and individuals who opt for this surgery are often perceived to be 'cheating.' This extended ethnographic study within one bariatric program in the Southwestern United States shows how patients conscientiously perform this productivity...
April 2017: Anthropology & Medicine
https://www.readbyqxmd.com/read/28288584/adipose-tissue-fibrosis-in-human-cancer-cachexia-the-role-of-tgf%C3%AE-pathway
#13
Michele Joana Alves, Raquel Galvão Figuerêdo, Flavia Figueiredo Azevedo, Diego Alexandre Cavallaro, Nelson Inácio Pinto Neto, Joanna Darck Carola Lima, Emidio Matos-Neto, Katrin Radloff, Daniela Mendes Riccardi, Rodolfo Gonzalez Camargo, Paulo Sérgio Martins De Alcântara, José Pinhata Otoch, Miguel Luiz Batista Junior, Marília Seelaender
BACKGROUND: Cancer cachexia is a multifactorial syndrome that dramatically decreases survival. Loss of white adipose tissue (WAT) is one of the key characteristics of cachexia. WAT wasting is paralleled by microarchitectural remodeling in cachectic cancer patients. Fibrosis results from uncontrolled ECM synthesis, a process in which, transforming growth factor-beta (TGFβ) plays a pivotal role. So far, the mechanisms involved in adipose tissue (AT) re-arrangement, and the role of TGFβ in inducing AT remodeling in weight-losing cancer patients are poorly understood...
March 14, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28286739/people-trying-to-lose-weight-dislike-calorie-counting-apps-and-want-motivational-support-to-help-them-achieve-their-goals
#14
Linda Solbrig, Ray Jones, David Kavanagh, Jon May, Tracey Parkin, Jackie Andrade
BACKGROUND: Two thirds of UK adults are overweight or obese and at increased risk of chronic conditions such as heart disease, diabetes and certain cancers. Basic public health support for weight loss comprises information about healthy eating and lifestyle, but internet and mobile applications (apps) create possibilities for providing long-term motivational support. AIMS: To explore among people currently trying to lose weight, or maintaining weight loss, (i) problems, experiences and wishes in regards to weight management and weight loss support including e-health support; (ii) reactions to Functional Imagery Training (FIT) as a possible intervention...
March 2017: Internet Interventions: the Application of Information Technology in Mental and Behavioural Health
https://www.readbyqxmd.com/read/28281891/understanding-the-challenge-of-weight-loss-maintenance-a-systematic-review-and-synthesis-of-qualitative-research-on-weight-loss-maintenance
#15
Colin Greaves, Leon Poltawski, Ruth Garside, Simon Briscoe
Behaviour change interventions can be effective in helping people to lose weight, but weight is often regained. Effective interventions are required to prevent this. We conducted a systematic review and synthesis of qualitative research on people's experiences of weight loss maintenance. We searched bibliographic databases for qualitative studies about the experience of currently or previously overweight adults trying to maintain weight loss. We thematically synthesised study findings to develop a model of weight loss maintenance...
March 10, 2017: Health Psychology Review
https://www.readbyqxmd.com/read/28275298/jianpi-qingchang-decoction-alleviates-ulcerative-colitis-by-inhibiting-nuclear-factor-%C3%AE%C2%BAb-activation
#16
Lie Zheng, Ya-Li Zhang, Yan-Cheng Dai, Xuan Chen, De-Liang Chen, Yue-Ting Dai, Zhi-Peng Tang
AIM: To investigate the therapeutic effect of Jianpi Qingchang decoction (JPQCD) on dextran sulfate sodium (DSS)-induced ulcerative colitis (UC) in mice. METHODS: C57BL/c mice were injected intragastrically with 5% DSS instead of drinking water for 7 d, and their body weight, diarrhea severity and fecal bleeding were monitored, while the mice in the control group were treated with standard drinking water, without DSS. After 7 d, the DSS drinking water was changed to normal water and the DSS group continued with DSS water...
February 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28271430/behavioral-treatment-for-veterans-with-obesity-24-month-weight-outcomes-from-the-aspire-va-small-changes-randomized-trial
#17
Lesley D Lutes, Laura J Damschroder, Robin Masheb, Hyungjin Myra Kim, Leah Gillon, Robert G Holleman, David E Goodrich, Julie C Lowery, Carol Janney, Susan Kirsh, Caroline R Richardson
BACKGROUND: Small Changes (SC) is a weight management approach that demonstrated superior 12-month outcomes compared to the existing MOVE!(®) Weight Management Program at two Veterans Affairs (VA) sites. However, approaches are needed to help graduates of treatment continue to lose or maintain their weight over the longer term. OBJECTIVE: The purpose of the present study was to examine the effectiveness of a second year of low-intensity SC support compared to support offered by the usual care MOVE! programs...
March 7, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28267846/change-in-percentages-of-adults-with-overweight-or-obesity-trying-to-lose-weight-1988-2014
#18
LETTER
Kassandra R Snook, Andrew R Hansen, Carmen H Duke, Kathryn C Finch, Amy A Hackney, Jian Zhang
No abstract text is available yet for this article.
March 7, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28267328/how-molecular-size-impacts-rmsd-applications-in-molecular-dynamics-simulations
#19
Karen Sargsyan, Cédric Grauffel, Carmay Lim
The root-mean-square deviation (RMSD) is a similarity measure widely used in analysis of macromolecular structures and dynamics. As increasingly larger macromolecular systems are being studied, dimensionality effects such as the "curse of dimensionality" (a diminishing ability to discriminate pairwise differences between conformations with increasing system size) may exist and significantly impact RMSD-based analyses. For such large bimolecular systems, whether the RMSD or other alternative similarity measures might suffer from this "curse" and lose the ability to discriminate different macromolecular structures had not been explicitly addressed...
March 16, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28265973/weight-change-and-risk-of-hyperglycaemia-in-elderly-women
#20
Katrine Dragsbæk, Jesper S Neergaard, Claus Christiansen, Morten A Karsdal, Henning Beck-Nielsen, Susanne Brix, Kim Henriksen
BACKGROUND: Hyperglycaemia increases the risk of type 2 diabetes, heart disease and stroke, and is influenced by weight. However, the impact of preceding weight change on blood glycemia levels in late-life is less well understood. AIM: We studied the interplay between weight change and risk of hyperglycaemia in a prospective cohort of elderly women. METHODS: Elderly Caucasian women (age: 67.1 years at baseline, n = 1173) enrolled in the Prospective Epidemiological Risk Factor study with baseline and 13-year follow-up measurements of BMI and fasting glucose levels (FPG) and no previous history of diabetes or impaired fasting glucose...
March 6, 2017: Aging Clinical and Experimental Research
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