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Li Li, Li Guo, Xingjie Chen, Mingli Xiang, Fang Yang, Jing-Chao Ren, Guang-Hui Zhang
Secondhand smoke (SHS) has adverse effects on health, particularly for children. Our purpose was to analyze the correlation between SHS exposure and heavy metal concentrations in children. The investigation was conducted in Xinxiang County, Henan Province, China, from August 2015 to December 2015. In total, 821 students (433 boys and 388 girls) were recruited, and the contents of heavy metals in their hair-including chromium, manganese, nickel, arsenic, lead, and cadmium-were detected by ICP-MS. The children's parents were informed, and a questionnaire was conducted, which included questions about smoking habits and demographic characteristics...
December 9, 2017: European Journal of Pediatrics
Javed Nawab, Saad Farooqi, Wang Xiaoping, Sardar Khan, Asad Khan
Food safety is a major concern worldwide and human beings are frequently exposed to potentially toxic metals (PTMs) through consumption of vegetables, fruits, and cereal crops grown in contaminated areas. The present study investigates the concentrations of PTMs such as chromium (Cr), nickel (Ni), zinc (Zn), arsenic (As), cadmium (Cd), and lead (Pb) in the foodstuffs (fruits, vegetables, and cereals) collected from different markets of Khyber Pakhtunkhwa, Pakistan. Samples of fruits (banana, tangerine, apple, and guava), vegetables (tomato, onion, potato, pea, and lady finger), and cereals (rice, kidney beans, and chick peas) were acid-extracted and analyzed using ICP-MS...
December 8, 2017: Environmental Science and Pollution Research International
Ilia Rodushkin, Cora Paulukat, Simon Pontér, Emma Engström, Douglas C Baxter, Dieke Sörlin, Nicola Pallavicini, Katerina Rodushkina
The performance of double focusing, sector field mass spectrometry (ICP-SFMS) for determination of analytes, including technology critical elements (TCE), at ultra-trace levels in environmental and clinical matrices was critically evaluated. Different configurations of the ICP-SFMS introduction system as well as various sample preparations, pre-concentration and matrix separation methods were employed and compared. Factors affecting detection capabilities and accuracy of data produced (instrumental sensitivity, contamination risks, purity of reagents, spectral interferences, matrix effects, analyte recovery and losses) were discussed...
December 4, 2017: Science of the Total Environment
Yongju He, Bowen Zeng, Shuquan Liang, Mengqiu Long, Hui Xu
Biodegradability is one of the most critical issues for silica-based nanodrug delivery systems, since it is crucial prerequisites for the successful translation in clinics. In this work, a novel mesoporous silica-calcium phosphate (MS-CAP) hybrid nanocarrier with a fast pH-responsive biodegradation rate was developed by a one-step method, where CAP precursors (Ca2+ and PO43-) were incorporated into silica matrix during the growth process. The morphology and structure of MS-CAP were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), N2 adsorption-desorption isotherms, fourier transformed infrared spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS)...
December 7, 2017: ACS Applied Materials & Interfaces
Sylwia Głazowska, Emiko Murozuka, Daniel Pergament Persson, Pedro Humberto Castro, Jan K Schjoerring
Silicon (Si) has many beneficial effects in plants, especially for the survival of biotic and abiotic stresses. However, Si may negatively affect the quality of lignocellulosic biomass for bioenergy purposes. Despite many studies, the regulation of Si distribution and deposition in plants remains to be fully understood. Here, we have identified the Brachypodium distachyon mutant low-silicon 1 (Bdlsi1-1), with impaired channelling function of the Si influx transporter BdLSI1, resulting in a substantial reduction of Si in shoots...
December 7, 2017: Physiologia Plantarum
Cornelis G Vos, Ruben van Veen, Richte Cl Schuurmann, Johannes T Boersen, Daniel Af van den Heuvel, Jean-Paul Pm de Vries
Background Early detection of small type I endoleaks after endovascular aneurysm sealing is mandatory because they can rapidly progress and lead to severe complications. Recognition of endoleaks can be challenging due to the appearances on computed tomography unique to endovascular aneurysm sealing. We aimed to validate the accuracy and added value of subtraction computed tomography imaging using a post-processing software algorithm to improve detection of endovascular aneurysm sealing-associated endoleaks on postoperative surveillance imaging...
January 1, 2017: Vascular
Frederick Adam Zeiler, Joseph Donnelly, David Menon, Peter Smieleweski, Peter John Hutchinson, Marek Czosnyka
To describe a new continuous index of physiologic measurement in a TBI population, the moving correlation coefficient between intracranial pressure (ICP) pulse amplitude (AMP) and cerebral perfusion pressure (CPP), which we refer to as RAC. We use patient examples of sustained intracranial hypertension, systemic arterial hypotension and plateau waves, as well as the retrospective analysis of 358 non-decompressive craniectomy (DC) traumatic brain injury (TBI) patients with high frequency ICP and ABP data, to explore the relationships of this new index, RAC, with AMP, ICP, CPP, RAP, pressure reactivity index (PRx) and pulse amplitude index (PAx)...
December 6, 2017: Journal of Neurotrauma
Hongwei Cheng, Xiang Mao, Zonggang Hou, Jian Xu, Shuyu Hao, Huan Li, Baiyun Liu
To discuss the relationship between the regional cerebral blood flow (rCBF) and cerebral perfusion pressure (CPP) and the effect of CPP on rCBF in different spaces in an experimental animal model. As the ICP increased, the CPP and rCBF (A × β value measured by CEU) decreased to varying degrees. The rCBF1 and rCBF2 were well correlated with the CPP. At the same CPP, rCBF1 decreased significantly than the level of rCBF2 (p < 0.01). Six healthy cross-breed dogs, both males and females, weighing 18.3 ± 1...
November 7, 2017: Oncotarget
Barbara Brodziak-Dopierała, Wojciech Roczniak, Agata Jakóbik-Kolon, Joanna Kluczka, Bogdan Koczy, Jerzy Kwapuliński, Magdalena Babuśka-Roczniak
BACKGROUND: Iron as a cofactor of enzymes takes part in the synthesis of the bone matrix. Severe deficiency of iron reduces the strength and mineral density of bones, whereas its excess may increase oxidative stress. In this context, it is essential to determine the iron content in knee joint tissues. OBJECTIVES: The study objective was to determine the level of iron in the tissues of the knee joint, i.e., in the femoral bone, tibia and meniscus. MATERIAL AND METHODS: Material for analysis was obtained during endoprosthetic surgery of the knee joint...
October 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Jeong In Choi, Song Ji Chae, Jung Min Kim, Jae Chun Choi, Se Jong Park, Hee Ju Choi, Hojae Bae, Hyun Jin Park
In recent years, silver nanoparticles (AgNPs) have been extensively employed in food packaging systems as a potential antibacterial agent. Although proven to be highly effective, increased number of AgNP-containing products raises concerns among consumers regarding the migration of AgNPs from the packaging material into foods which may exert toxic effects. To address this, five baby products were chosen (baby bottle A, baby bottle B, pacifier A, pacifier B, and breastmilk storage bag) to investigate AgNPs migration into three food simulants (deionized water, 4% acetic acid (w/v), and 50% ethanol (v/v)) using inductively coupled plasma mass spectrometry (ICP-MS)...
December 6, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
Giuseppa Di Bella, Gianluca Pizzullo, Giuseppe Daniel Bua, Angela Giorgia Potortì, Antonello Santini, Salvatore Giacobbe
The nickel, chromium, arsenic, cadmium, and lead content have been evaluated, by ICP-MS, in digestive gland of the amphiatlantic gastropod Stramonita haemastoma, sampled along the highly anthropized Gulf of Milazzo (Central Mediterranean). Concentrations notably higher than those reported in literature for other Mediterranean Muricidae have been recorded. The results also indicated a different impact in different sites, according to distribution and typology of human activities, whilst recorded seasonal variations might relate with rapid metabolic response...
December 6, 2017: Environmental Monitoring and Assessment
Aruã C da Silva, Tatiana Augusto, Leandro H Andrade, Susana I Córdoba de Torresi
A novel electroactive macromonomer based on poly(l-lactic acid) (PLLA) with (3,4-ethylenedioxythiophene) (EDOT) functional end groups, was prepared by a traditional approach of organometallic polymerization with stannous octanoate [Sn(oct2)] and enzymatic polymerization using immobilized Candida antarctica Lipase B (CAL-B) and Amano lipase Pseudomonas cepacia(PS-IM), as catalysts. In the synthetic strategy, (2,3-dihydrothieno[3,4-b] dioxin-2-yl)methanol (EDOT-OH) was used to initiate the ring opening polymerization of lactide to yield PLLA with EDOT end group...
February 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
Gunjan Desai, Prasad Pande, Chandralekha Tampi, Prasad Wagle
Autoimmune Pancreatitis (AIP) presents in two forms - Type I or lymphoplasmacytic sclerosing pancreatitis and Type II or idiopathic ducto-centric pancreatitis (IDCP). AIP II is rare in south Asia and, especially so, in India. Most patients have either Idiopathic Chronic Pancreatitis (ICP) or alcohol related chronic pancreatitis. AIP Type I has been described in India. We herein report a patient who had features of ICP on imaging, for whom surgery was performed to relieve chronic pancreatic pain. However, the pathologic features revealed AIP Type II or IDCP...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
Christina Herland Fløtre, Kristin Varsi, Thea Helm, Bjørn Bolann, Anne-Lise Bjørke-Monsen
BACKGROUND: The toxic trace elements mercury (Hg), lead (Pb), cadmium (Cd) and antimony (Sb) are transferred over the placenta to the fetus and secreted into the breastmilk. All four elements bioaccumulate in the body and as maternal age at delivery is increasing in industrialized countries, the burden of toxic trace elements in never-pregnant women of fertile age is of concern. METHODS: Healthy, never-pregnant women aged 18 to 40 years (n = 158) were recruited between June 2012 and March 2015 in Bergen, Norway...
2017: PloS One
Roziana Ramli, Mohd Yamani Idna Idris, Khairunnisa Hasikin, Noor Khairiah A Karim, Ainuddin Wahid Abdul Wahab, Ismail Ahmedy, Fatimah Ahmedy, Nahrizul Adib Kadri, Hamzah Arof
Retinal image registration is important to assist diagnosis and monitor retinal diseases, such as diabetic retinopathy and glaucoma. However, registering retinal images for various registration applications requires the detection and distribution of feature points on the low-quality region that consists of vessels of varying contrast and sizes. A recent feature detector known as Saddle detects feature points on vessels that are poorly distributed and densely positioned on strong contrast vessels. Therefore, we propose a multiresolution difference of Gaussian pyramid with Saddle detector (D-Saddle) to detect feature points on the low-quality region that consists of vessels with varying contrast and sizes...
2017: Journal of Healthcare Engineering
Lei Feng, Lei Cai, Guo-Lin He, Jun Weng, Yang Li, Ming-Xin Pan, Ze-Sheng Jiang, Qing Peng, Yi Gao
AIM: To establish a simplified, reproducible D-galactosamine-induced cynomolgus monkey model of acute liver failure having an appropriate treatment window. METHODS: Sixteen cynomolgus monkeys were randomly divided into four groups (A, B, C and D) after intracranial pressure (ICP) sensor implantation. D-galactosamine at 0.3, 0.25, 0.20 + 0.05 (24 h interval), and 0.20 g/kg body weight, respectively, was injected via the small saphenous vein. Vital signs, ICP, biochemical indices, and inflammatory factors were recorded at 0, 12, 24, 36, 48, 72, 96, and 120 h after D-galactosamine administration...
November 14, 2017: World Journal of Gastroenterology: WJG
Jin Eun, Joon Huh, Seo-Yeon Yang, Han-Yong Huh, Jae-Kun Ahn, Kwang-Wook Cho, Young-Woo Kim, Sung-Lim Kim, Jong-Tae Kim, Do-Sung Yoo, Hae-Kwan Park, Cheol Ji
OBJECTIVE: In the severe traumatic brain injured (TBI) patient, maintaining the systolic blood pressure (BP) over 90 mmHg, the intracranial pressure (ICP) under 20 mmHg and the cerebral perfusion pressure (CPP) greater than 60∼70 mmHg is recommended to improve clinical outcomes. But a recommended CPP value for patients treated with decompression craniectomy (DC) is not clearly studied. The authors tried to determine whether the targeted CPP can be lowered in patients with DC. METHODS: 191 patients underwent DC for TBI included in this retrospective analysis...
December 1, 2017: World Neurosurgery
Peter Hendrickson, Jim Pridgeon, Nancy Temkin, Sureyya Dikmen, Walter Videtta, Gustavo Petroni, Silvia Lujan, Nahuel Guadagnoli, Zulma Urbina, Perla Blanca Pahnke, Daniel Godoy, Gustavo Pinero, Freddy Sandi Lora, Sergio Aguilera, Andres Rubiano, Caridad Soler Morejon, Manuel Jibaja, Hubiel Lopez, Ricardo Romero, Kelley Chaddock, Randall M Chesnut
BACKGROUND: Severe TBI (sTBI) is a significant global health problem disproportionately affecting Low and Middle Income Countries (LMICs). Management of intracranial hypertension in sTBI is crucial to survival and optimal recovery. High Income Country practitioners routinely use Intracranial Pressure (ICP) monitors although their utility has been questioned. ICP monitors are usually unavailable in LMICs. No consensus based/tested protocols or literature exists for sTBI treatment without ICP monitoring...
December 1, 2017: World Neurosurgery
Juhyun Park, Ji Sun Chai, Soo Woong Kim, Jae-Seung Paick, Min Chul Cho
OBJECTIVE: To determine whether JNK inhibition could alleviate erectile dysfunction (ED) through suppressing cavernosal apoptosis in a rat model of carvernosal nerve crush injury (CNCI), thereby providing potential therapeutic strategy for alleviating post-radical prostatectomy (RP) ED. MATERIALS AND METHODS: Fifty-six 11-week-old male Sprague-Dawley rats were categorized equally into the following four groups: 1) sham surgery (S), 2) CNCI (I), 3) CNCI treated with low-dose JNK inhibitor (L), and 4) CNCI treated with high-dose JNK inhibitor (H)...
December 1, 2017: Urology
Yin-Yin Xu, Wen-Juan Lv, Cui-Ling Ren, Xiao-Ying Niu, Hong-Li Chen, Xing-Guo Chen
The popularity of novel nanoparticles coated capillary column has aroused widespread attention of researchers. Metal organic frameworks (MOFs) with special structure and chemical properties have received great interest in separation sciences. This work presents the investigation of HKUST-1 (Hong Kong University of Science and Technology-1, called Cu3(BTC)2 or MOF-199) nanoparticles as a new type of coating material for capillary electrochromatography. For the first time, three layers coating (3-LC), five layers coating (5-LC), ten layers coating (10-LC), fifteen layers coating (15-LC), twenty layers coating(20-LC) and twenty-five layers coating (25-LC) capillary columns coated with HKUST-1 nanoparticles were synthesized by covalent bond with in situ, layer-by-layer self-assembly approach...
November 29, 2017: Journal of Chromatography. A
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