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https://www.readbyqxmd.com/read/28468207/management-of-rhinophyma-outcomes-study-of-the-subunit-method
#1
Aladdin H Hassanein, Raj M Vyas, Jessica Erdmann-Sager, Edward J Caterson, Julian J Pribaz
BACKGROUND: Rhinophyma causes a nasal deformity and functional airway obstruction. Partial excision (eg, tangential) with secondary healing commonly removes hypertrophic soft tissues but does not improve nasal support. The subunit method for rhinophyma uses 6 nasal flaps to provide exposure for removal of rhinophymatous tissue and enhance structure. The purpose of this study was to evaluate outcomes of subunit method. METHODS: Medical records of patients with rhinophyma treated with the subunit method between 2013 and 2016 were analyzed...
May 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28405749/the-anterior-commissure-of-the-human-larynx-revisited
#2
Jean Michel Prades, M Peoc'h, C Petcu, A Karkas, J M Dumollard, M Gavid
BACKGROUND: The anterior commissure (AC) of the human larynx is usually understood as an area of the glottis anteriorly situated between the two vocal folds inserting to the thyroid cartilage (TC). The pattern of spread of AC carcinoma could hypothesize that AC could include other structures of the ventral larynx as developmental anatomy could demonstrate. METHODS: Ten adult larynx specimens from donation program cadavers and 15 selected fetal specimens (from 11 to 34 weeks of amenorrhoea) were studied using microdissection and histological serial sections stained with hematoxylin-eosin and reticuline...
April 12, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28388799/dorsal-augmentation-using-autologous-costal-cartilage-or-microfat-infused-soft-tissue-augmentation
#3
Dean M Toriumi
Costal cartilage grafting is increasing in popularity with increased demand for augmentation rhinoplasty and increased need for grafting material for structure rhinoplasty techniques. Use of costal cartilage for dorsal grafting is both art and science. The art is demonstrated in the act of carving a dorsal graft that will reflect the actual contour of the nasal dorsum. The science is linked to the methodology of how the grafts are contoured to match the patient's desires and how the graft is fixed to the bony dorsum to minimize the risk of warping and displacement...
April 2017: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/28346290/endoscopic-ear-surgery-for-external-auditory-canal-cholesteatoma
#4
Jörg Dähn, Lukas Anschuetz, Masaya Konishi, Mark Sayles, Marco Caversaccio, Patrick Dubach
BACKGROUND: Treatment of external auditory canal cholesteatoma (EACC) has been a question of debate. To our knowledge and according to a systematic review of endoscopic ear surgery (EES) in 2015, this study describes for the first time the technique and outcome by solely transcanal EES for EACC. STUDY METHOD: Retrospective case series, level of evidence IV. METHODS: Between October 2014 and December 2016, nine patients with unilateral EACC have been treated by EES...
June 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28304079/endoscope-or-microscope-guided-pediatric-tympanoplasty-comparison-of-grafting-technique-and-outcome
#5
Adrian L James
OBJECTIVES/HYPOTHESIS: To review experience from the introduction of totally endoscopic ear surgery (TEES) to a pediatric tympanoplasty practice to identify factors influencing technique selection and successful outcome. STUDY DESIGN: Prospective cohort study. METHODS: Analysis of prospectively acquired data from a consecutive series of 295 surgeries for tympanic membrane perforation over a 12-year period. Success of perforation closure was compared between microscope and TEES grafting techniques...
March 17, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28134644/management-of-rhinophyma-outcomes-study-of-the-subunit-method
#6
Aladdin H Hassanein, Raj M Vyas, Jessica Erdmann-Sager, Edward J Caterson, Julian J Pribaz
BACKGROUND: Rhinophyma causes a nasal deformity and functional airway obstruction. Partial excision (eg, tangential) with secondary healing commonly removes hypertrophic soft tissues but does not improve nasal support. The subunit method for rhinophyma uses 6 nasal flaps to provide exposure for removal of rhinophymatous tissue and enhance structure. The purpose of this study was to evaluate outcomes of subunit method. METHODS: Medical records of patients with rhinophyma treated with the subunit method between 2013 and 2016 were analyzed...
January 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28094473/transmeatal-tympanoplasty-of-subtotal-and-anterior-perforations-a-single-institution-experience-including-94-patients
#7
E A J de Savornin Lohman, J Borgstein
No abstract text is available yet for this article.
January 17, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28032157/a-rare-case-of-endochondral-pseudocyst-of-the-auricle
#8
Yahya Baltu, Utku Can Dölen, Orhan Aydin
Endochondral pseudocyst of the auricle is a very rare, benign, non-inflammatory cystic lesion. It most commonly develops in the scaphoid or triangular fossa of the ear. In this case report, we present a 46-year-old man with a painless lesion on the scaphoid fossa of the right ear. We removed the hypertrophic perichondrium forming the anterior wall of the pseudocyst, curetted the ear cartilage, and dressed it with compression. No complications, such as infection, seroma, or hematoma, occurred during the postoperative period...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28027321/elevated-fibroblast-growth-factor-signaling-is-critical-for-the-pathogenesis-of-the-dwarfism-in-evc2-limbin-mutant-mice
#9
Honghao Zhang, Nobuhiro Kamiya, Takehito Tsuji, Haruko Takeda, Greg Scott, Sudha Rajderkar, Manas K Ray, Yoshiyuki Mochida, Benjamin Allen, Veronique Lefebvre, Irene H Hung, David M Ornitz, Tetsuo Kunieda, Yuji Mishina
Ellis-van Creveld (EvC) syndrome is a skeletal dysplasia, characterized by short limbs, postaxial polydactyly, and dental abnormalities. EvC syndrome is also categorized as a ciliopathy because of ciliary localization of proteins encoded by the two causative genes, EVC and EVC2 (aka LIMBIN). While recent studies demonstrated important roles for EVC/EVC2 in Hedgehog signaling, there is still little known about the pathophysiological mechanisms underlying the skeletal dysplasia features of EvC patients, and in particular why limb development is affected, but not other aspects of organogenesis that also require Hedgehog signaling...
December 2016: PLoS Genetics
https://www.readbyqxmd.com/read/28027179/sliced-costochondral-chip-grafts-in-posttraumatic-enophthalmos-correction
#10
Tae-Hoon Kim, Ie-Hyon Park, Sa-Hyeok Hong, Seok-Chan Eun
BACKGROUND: Posttraumatic enophthalmos is a relatively common problem following orbitozygomatic fractures. However, inadequate long-term results are frequently observed due to the difficulty of performing intraoperative fine adjustments to soft-tissue volume and orbital size and gradual absorption of some grafted materials. Here, the authors describe an efficient method of enophthalmos correction using sliced costochondral bone and cartilage combination grafts. METHODS: From 2005 to 2011, the authors corrected enophthalmos in 12 patients using sliced costochondral grafts...
March 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28005788/bone-marrow-stem-cells-and-ear-framework-reconstruction
#11
Hamid Karimi, Seyed-Abolhassan Emami, Mohammad-Kazem Olad-Gubad
BACKGROUND: Repair of total human ear loss or congenital lack of ears is one of the challenging issues in plastic and reconstructive surgery. OBJECTIVE: The aim of the present study was 3D reconstruction of the human ear with cadaveric ear cartilages seeded with human mesenchymal stem cells. METHOD: We used cadaveric ear cartilages with preserved perichondrium. The samples were divided into 2 groups: group A (cartilage alone) and group B (cartilage seeded with a mixture of fibrin powder and mesenchymal stem cell [1,000,000 cells/cm] used and implanted in back of 10 athymic rats)...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27999805/efficiency-of-human-epiphyseal-chondrocytes-with-differential-replication-numbers-for-cellular-therapy-products
#12
Michiyo Nasu, Shinichiro Takayama, Akihiro Umezawa
The cell-based therapy for cartilage or bone requires a large number of cells; serial passages of chondrocytes are, therefore, needed. However, fates of expanded chondrocytes from extra fingers remain unclarified. The chondrocytes from human epiphyses morphologically changed from small polygonal cells to bipolar elongated spindle cells and to large polygonal cells with degeneration at early passages. Gene of type II collagen was expressed in the cells only at a primary culture (Passage 0) and Passage 1 (P1) cells...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27904024/cartilage-attachment-morphology-of-the-fetal-cruciate-ligaments-of-the-knee-an-immunohistochemical-study-using-human-fetal-specimens
#13
Masahito Yamamoto, Hiromasa Takada, Takeshi Takayama, Sakura Katsumura, Mayumi Sato, Hiroshi Abe, Gen Murakami, Shin-Ichi Abe
Fetal cruciate ligaments of the knee provide two types of cartilage attachments: to a cartilage fovea or a simple continuation to the perichondrium. To examine a difference in matrix substance between a ligament attachment to the fovea and another attachment to the perichondrium. We histologically observed 12 human fetal femurs in which the posterior (or anterior) cruciate ligament provided a fovea-type (or a perichondrium-type) attachment. Immunohistochemistry of matric substances (aggrecan, versican, tenascin-c) was performed...
2016: Okajimas Folia Anatomica Japonica
https://www.readbyqxmd.com/read/27892493/autologous-temporomandibular-joint-reconstruction-independent-of-exogenous-additives-a-proof-of-concept-study-for-guided-self-generation
#14
Jiao Wei, Tanja Herrler, Dong Han, Kai Liu, Rulin Huang, Markus Guba, Chuanchang Dai, Qingfeng Li
Joint defects are complex and difficult to reconstruct. By exploiting the body's own regenerative capacity, we aimed to individually generate anatomically precise neo-tissue constructs for autologous joint reconstruction without using any exogenous additives. In a goat model, CT scans of the mandibular condyle including articular surface and a large portion of the ascending ramus were processed using computer-aided design and manufacturing. A corresponding hydroxylapatite negative mold was printed in 3D and temporarily embedded into the transition zone of costal periosteum and perichondrium...
November 28, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27890611/histone-methyltransferase-setdb1-is-indispensable-for-meckel-s-cartilage-development
#15
Kohei Yahiro, Norihisa Higashihori, Keiji Moriyama
The histone methyltransferase Setdb1 represses gene expression by catalyzing lysine 9 of histone H3 trimethylation. Given that the conventional knockout of Setdb1 is embryo-lethal at the implantation stage, its role in craniofacial development is poorly understood. Here, we investigated the role of Setdb1, using conditional knockout mice-in which Setdb1 was deleted in the Meckel's cartilage (Setdb1 CKO)-and the mouse chondrogenic cell line ATDC5-in which Setdb1 was inhibited by siRNA. Deletion of Setdb1 in Meckel's cartilage, the supportive tissue in the embryonic mandible, led to its enlargement, instead of the degeneration that normally occurs...
January 22, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/27868204/bioengineering-pediatric-scaffold-free-auricular-cartilaginous-constructs
#16
Pedram Akbari, Stephen D Waldman, Sharon L Cushing, Blake C Papsin, Evan J Propst, Joanna F Weber, Herman Yeger, Walid A Farhat
OBJECTIVE: The use of exogenous materials as scaffolds in cartilage tissue engineering has limited the clinical application of resultant constructs due to the risk of postoperative complications. In an effort to minimize such complications, we aim to generate human, scaffold-free auricular cartilaginous constructs. STUDY DESIGN: Laboratory study using pediatric auricular cartilage. METHODS: Remnant, normal pediatric auricular cartilage samples that would have otherwise been discarded were collected and digested to free cells...
May 2017: Laryngoscope
https://www.readbyqxmd.com/read/27853694/autologous-diced-cartilage-in-nasal-septoplasty
#17
Sameh Ibrahim Sersar, Ibrahim Yassin, Mohammed Saad Eldin Aly
Diced rib cartilage is an acceptable option in severe nasal deformities. We present our preliminary experience in KAMC in nasal septoplasties using the autologous diced costal cartilage. This is a retrospective study of the 22 cases who needed the autologous diced costal cartilage in our centre in 4 years. All our patients needed autologous diced rib cartilages. Twelve were wrapped with temporalis fascia, eight needed rectus fascia and perichondrium was used in only 2 cases. The naso-frontal angle for the whole series decreased by a mean of 4...
September 2016: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/27832272/use-of-costal-perichondrium-as-an-interpositional-graft-for-septal-perforation-closure
#18
Dean M Toriumi, Quintin M Cappelle, Victor Chung
Importance: Closure of septal perforations remains a technically difficult procedure to perform. Objective: To assess the use of costal perichondrium as an interpositional graft to enhance closure of septal perforations using bilateral mucosal flaps and the effectiveness of the procedure. Design, Setting, and Participants: This case series included all 51 consecutive patients presenting with septal perforations from January 1, 2006, to August 31, 2014, at a single institution...
March 1, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/27830876/positional-changes-in-tendon-insertions-from-bone-to-fascia-development-of-the-pes-anserinus-and-semimembranosus-muscle-insertion-in-human-foetuses
#19
Z W Jin, H Abe, Y Jin, S Shibata, G Murakami, Jo F Rodríguez-Vázquez
Development of a long muscle belly in foetal extremities generally requires a definite bony insertion of the long tendon. However, in adults, the pes anserinus and the semimembranosus tendon (SMT) are inserted into fasciae. Development of fascial insertions in foetuses was investigated by examining serial histological sections obtained from 7 foetuses at 8-9 weeks and 8 foetuses at 14-16 weeks. The presence of matrix substances and macrophages was also examined by immunohistochemistry. At 8 weeks, the tendons of the semitendinosus, gracilis, sartorius and semimembranosus muscles were straight and inserted into the initial shaft-like proximal end of the tibia on the proximal side of the popliteus muscle...
2016: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/27806676/the-role-of-cell-seeding-bioscaffolds-and-the-in-vivo-microenvironment-in-the-guided-generation-of-osteochondral-composite-tissue
#20
Jiao Wei, Tanja Herrler, Kai Liu, Dong Han, Mei Yang, Chuanchang Dai, Qingfeng Li
Tissue engineering based on cell seeding, bioscaffolds, and growth factors has been widely applied for the reconstruction of tissue defects. Recent progress has fueled in vivo tissue engineering techniques in becoming hot topics in regenerative medicine and reconstructive surgery. To improve the efficacy of tissue engineering, we here investigated the roles of cell seeding, bioscaffolds, growth factors, and in vivo microenvironment (IM) in tissue regeneration. Bone marrow-derived stem cells, allogeneic demineralized bone matrix as bioscaffold, and growth factor bone morphogenetic protein 2/transforming growth factor, and the IM of rib periosteum and perichondrium were used in different combinations for the generation of osteochondral composite tissue...
December 2016: Tissue Engineering. Part A
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