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Visual field defect

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https://www.readbyqxmd.com/read/28211185/a-comparison-of-goldmann-iii-v-and-spatially-equated-test-stimuli-in-visual-field-testing-the-importance-of-complete-and-partial-spatial-summation
#1
Jack Phu, Sieu K Khuu, Barbara Zangerl, Michael Kalloniatis
PURPOSE: Goldmann size V (GV) test stimuli are less variable with a greater dynamic range and have been proposed for measuring contrast sensitivity instead of size III (GIII). Since GIII and GV operate within partial summation, we hypothesise that actual GV (aGV) thresholds could predict GIII (pGIII) thresholds, facilitating comparisons between actual GIII (aGIII) thresholds with pGIII thresholds derived from smaller GV variances. We test the suitability of GV for detecting visual field (VF) loss in patients with early glaucoma, and examine eccentricity-dependent effects of number and depth of defects...
March 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28209521/impaired-visual-competition-in-patients-with-homonymous-visual-field-defects
#2
A C Geuzebroek, A V van den Berg
Intense visual training can lead to partial recovery of visual field defects caused by lesions of the primary visual cortex. However, the standard visual detection and discrimination tasks, used to assess this recovery process tend to ignore the complexity of the natural visual environment, where multiple stimuli continuously interact. Visual competition is an essential component for natural search tasks and detecting unexpected events. Our study focused on visual decision-making and to what extent the recovered visual field can compete for attention with the 'intact' visual field...
February 13, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28199381/impact-of-the-anti-aquaporin-4-autoantibody-on-inner-retinal-structure-function-and-structure-function-associations-in-japanese-patients-with-optic-neuritis
#3
Yoshiko Matsumoto, Sotaro Mori, Kaori Ueda, Takuji Kurimoto, Akiyasu Kanamori, Yuko Yamada, Ichiro Nakashima, Makoto Nakamura
PURPOSE: An autoantibody against aquaporin-4 (AQP4 Ab) is highly specific for neuromyelitis optica spectrum disorder and plays a pathogenic role in this disease. The purpose of this study was to investigate the impact of AQP4 Ab on inner retinal structure, function, and the structure-function relationships in eyes with optic neuritis. METHODS: Thirty five eyes from 25 cases who had received visual function tests and RTVue optical coherence tomography (OCT) measurement at least six months after the latest episode of optic neuritis were enrolled...
2017: PloS One
https://www.readbyqxmd.com/read/28196732/peripapillary-and-macular-vessel-density-in-patients-with-glaucoma-and-single-hemifield-visual-field-defect
#4
Adeleh Yarmohammadi, Linda M Zangwill, Alberto Diniz-Filho, Luke J Saunders, Min Hee Suh, Zhichao Wu, Patricia Isabel C Manalastas, Tadamichi Akagi, Felipe A Medeiros, Robert N Weinreb
PURPOSE: To compare hemifield differences in the vessel density of the peripapillary and macula in open-angle glaucoma eyes with visual field (VF) defect confined to one hemifield using optical coherence tomography angiography (OCT-A). DESIGN: Cross-sectional study. PARTICIPANTS: A total of 58 eyes of 58 patients with glaucoma with VF loss confined to a single hemifield and 28 healthy eyes. METHODS: Retinal vasculature information was summarized as circumpapillary vessel density (cpVD) and perifoveal vessel density (pfVD)...
February 10, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28195890/medial-orbital-wall-reconstruction-with-porous-polyethylene-by-using-a-transconjunctival-approach-with-a-caruncular-extension
#5
Chieh Chou, Yur-Ren Kuo, Chien-Chang Chen, Cheng-Sheng Lai, Sin-Daw Lin, Shu-Hung Huang, Su-Shin Lee
BACKGROUND: The reported rate of isolated medial orbital wall fractures varies widely but has been found to be as high as 55% of all orbital fractures. Identifying and repairing medial orbital wall defects by using appropriate materials improves patient outcome considerably; however, most related research has focused on orbital floor defect management rather than medial orbital wall treatment, and no consensus on repairing medial orbital wall fractures exists. Furthermore, medial orbital wall fracture is a main cause of posttraumatic enophthalmos...
February 14, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28192385/ganglion-cell-complex-loss-in-chiasmal-compression-by-brain-tumors
#6
Marisa G Tieger, Thomas R Hedges, Joseph Ho, Natalie K Erlich-Malona, Laurel N Vuong, Geetha K Athappilly, Carlos E Mendoza-Santiesteban
BACKGROUND: Patterns of ganglion cell complex (GCC) loss detected by optical coherence tomography provide an objective measure of optic nerve injury. These patterns aid in early diagnosis and localization of chiasmal lesions. METHODS: Twenty-three patients with chiasmal compression seen between 2010 and 2015 were imaged with the Cirrus high-definition optical coherence tomography macular cube 512 × 128, retinal nerve fiber layer (RNFL) scan protocols and automated (30-2 Humphrey) visual fields (VFs)...
March 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28180039/endoscopic-endonasal-optic-nerve-decompression-for-fibrous-dysplasia
#7
Timothy R DeKlotz, S Tonya Stefko, Juan C Fernandez-Miranda, Paul A Gardner, Carl H Snyderman, Eric W Wang
Objective To evaluate visual outcomes and potential complications for optic nerve decompression using an endoscopic endonasal approach (EEA) for fibrous dysplasia. Design Retrospective chart review of patients with fibrous dysplasia causing extrinsic compression of the canalicular segment of the optic nerve that underwent an endoscopic endonasal optic nerve decompression at the University of Pittsburgh Medical Center from 2010 to 2013. Main Outcome Measures The primary outcome measure assessed was best-corrected visual acuity (BCVA) with secondary outcomes, including visual field testing, color vision, and complications associated with the intervention...
February 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28179979/flexible-gastro-intestinal-endoscopy-clinical-challenges-and-technical-achievements
#8
REVIEW
Niehls Kurniawan, Martin Keuchel
Flexible gastro-intestinal (GI) endoscopy is an integral diagnostic and therapeutic tool in clinical gastroenterology. High quality standards for safety, patients' comfort, and efficiency have already been achieved. Clinical challenges and technical approaches are discussed in this short review. Image enhanced endoscopy for further characterization of mucosal and vascular patterns includes dye-spray or virtual chromoendoscopy. For confocal laser endoscopy, endocytoscopy, and autofluorescence clinical value has not yet been finally evaluated...
2017: Computational and Structural Biotechnology Journal
https://www.readbyqxmd.com/read/28170483/diagnosis-and-treatment-of-pituitary-adenomas-a-review
#9
Mark E Molitch
Importance: Pituitary adenomas may hypersecrete hormones or cause mass effects. Therefore, early diagnosis and treatment are important. Observations: Prevalence of pituitary adenomas ranges from 1 in 865 adults to 1 in 2688 adults. Approximately 50% are microadenomas (<10 mm); the remainder are macroadenomas (≥10 mm). Mass effects cause headache, hypopituitarism, and visual field defects. Treatments include transsphenoidal surgery, medical therapies, and radiotherapy...
February 7, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28169924/retrograde-maculopathy-in-patients-with-glaucoma
#10
Jacqueline Brazerol, Milko E Iliev, René Höhn, Stephan Fränkl, Hilary Grabe, Mathias Abegg
PURPOSE: Macular optical coherence tomography (OCT) analysis can be used for quantitative measures of optic nerve atrophy at a location far from the optic nerve head. This recently led to the finding of microcystic macular edema (MME), that is vacuolar inclusions in the macular inner nuclear layer, in some glaucoma patients. The involvement of individual retinal layers is yet unclear in glaucoma. In this study we systematically investigated glaucoma-induced changes in macular layers to evaluate whether glaucoma-associated damage extends beyond the macular ganglion cell layer...
February 6, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28169283/ultra-high-resolution-profiles-of-macular-intra-retinal-layer-thicknesses-and-associations-with-visual-field-defects-in-primary-open-angle-glaucoma
#11
Qi Chen, Shenghai Huang, Qingkai Ma, Huiling Lin, Mengmeng Pan, Xinting Liu, Fan Lu, Meixiao Shen
The structural characteristics of the outer retinal layers in primary open angle glaucoma (POAG) are still controversial, and these changes, along with those in the inner retinal layers, could have clinical and/or pathophysiological significance. A custom-built ultra-high resolution optical coherence tomography (UHR-OCT) combined with an automated segmentation algorithm can image and measure the eight intra-retinal layers. The purpose of this study is to determine the thickness characteristics of the macular intra-retinal layers, especially the outer layers, in POAG patients...
February 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28161915/assessing-precision-of-hodapp-parrish-anderson-criteria-for-staging-early-glaucomatous-damage-in-an-ocular-hypertension-cohort-a-retrospective-study
#12
Tutul Chakravarti
PURPOSE: The aims of the study were (1) to stage early glaucomatous field defects following Hodapp-Parrish-Anderson (HPA) criteria in an ocular hypertension (OH) cohort with 7-year follow-up and (2) to recognize the limitation(s) of this staging system. DESIGN: A retrospective review of subjects with OH. METHODS: A retrospective review of the visual fields of 183 OH subjects was conducted. A Humphrey Field Analyzer was used for standard automated perimetry in all these participants, tested once every half year for 7 years or until the onset of conversion (study end point)...
January 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28156180/diagnosis-of-optic-nerve-sheath-meningioma-during-optic-nerve-sheath-decompression
#13
Austin R Meeker, Melissa W Ko, Bryant P Carruth, Kenneth B Strumpf, Thomas A Bersani
Optic nerve sheath meningioma (ONSM) is typically diagnosed based on clinical suspicion and imaging characteristics and is most often treated with radiation. Historically, biopsy, optic nerve sheath decompression, and debulking surgeries have been avoided for fear of optic nerve vascular disruption and tumor spread into the orbit. This is a case of a 48-year-old man who presented with unilateral optic disc edema, declining visual acuity, and a visual field defect. Despite an initial improvement with acetazolamide, his vision subsequently worsened...
February 3, 2017: Orbit
https://www.readbyqxmd.com/read/28152106/relationship-between-optical-coherence-tomography-sector-peripapillary-angioflow-density-and-octopus-visual-field-cluster-mean-defect-values
#14
Gábor Holló
PURPOSE: To compare the relationship of Octopus perimeter cluster mean-defect (cluster MD) values with the spatially corresponding optical coherence tomography (OCT) sector peripapillary angioflow vessel-density (PAFD) and sector retinal nerve fiber layer thickness (RNFLT) values. METHODS: High quality PAFD and RNFLT images acquired on the same day with the Angiovue/RTVue-XR Avanti OCT (Optovue Inc., Fremont, USA) on 1 eye of 27 stable early-to-moderate glaucoma, 22 medically controlled ocular hypertensive and 13 healthy participants were analyzed...
2017: PloS One
https://www.readbyqxmd.com/read/28142061/establishment-of-a-schizophrenic-animal-model-through-chronic-administration-of-mk-801-in-infancy-and-social-isolation-in-childhood
#15
Weiqing Liu, Xiuyan Wang, Wenjuan Hong, Dong Wang, Xiaogang Chen
BACKGROUND: Although an increasing amount of evidence supports a "two-hit" hypothesis for the neurodevelopmental model of schizophrenia, there has been no development in animal models to test this hypothesis. METHODS: An animal model was established by chronic administration of 0.1, 0.3, and 0.5mg/kg MK-801 in P7-P21 rats followed by four weeks of social isolation in childhood and then five days of social housing. Animal behaviors were measured by the open field (OF) test, the novel object recognition (NOR) test, the prepulse inhibition (PPI) test, and the elevated plus maze (EPM) test...
January 28, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/28128794/patching-retinal-breaks-with-seprafilm-for-treating-retinal-detachments-in-humans-9-years-of-follow-up
#16
M Haruta, M Arai, J Sueda, T Hirose, R Yamakawa
PurposeTo describe the long-term surgical outcomes of four patients treated for retinal detachment using Seprafilm as a novel technique.MethodsRetinal breaks in four eyes were covered with Seprafilm using a transvitreal approach after cataract surgery, pars plana vitrectomy, fluid-air exchange, and laser photocoagulation. Neither long-standing gas nor silicone oil was used. The patients were not instructed to maintain a specific head positioning postoperatively.ResultsSuccessful retinal reattachment was achieved with a single surgery in all four eyes, and none developed proliferative vitreoretinopathy...
January 27, 2017: Eye
https://www.readbyqxmd.com/read/28127658/inner-retinal-layer-change-in-glaucoma-patients-receiving-anti-vegf-for-neovascular-age-related-macular-degeneration
#17
Rafidah Saleh, Aashraya Karpe, Martin S Zinkernagel, Marion R Munk
PURPOSE: The purpose was to evaluate the effects of long-term anti-VEGF treatment on the retinal nerve fiber layer (RNFL) and retinal ganglion cell layer (RGCL) thickness for patients with neovascular AMD and glaucoma. METHODS: Medical records of respective patients who had received more than 15 anti-VEGF injections were reviewed. Initial and latest SD-OCT macular scans were segmented and changes of the RNFL and RGCL thickness at the four outer ETDRS quadrants were evaluated...
January 27, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28125859/visual-field-assessment-in-high-myopia-with-and-without-tilted-optic-disc
#18
Nasser Shoeibi, Nasrin Moghadas Sharif, Ramin Daneshvar, Asieh Ehsaei
BACKGROUND: The aim was to evaluate the effect of the tilted optic disc on the visual field in highly myopic eyes. METHODS: A total of 58 eyes from 58 highly myopic individuals underwent detailed ophthalmic examination and were categorised into two groups according to the presence of a tilted optic disc. The visual field of 20 eyes (mean age of 28.95 ± 7.22 years) with tilted optic discs were compared with 38 eyes (mean age of 27.87 ± 6.08 years) of control subjects without tilted optic discs using the 30-2 SITA standard protocol with a Humphrey Field Analyzer - HFA II-i...
January 26, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28125740/retinal-nerve-fiber-layer-may-be-better-preserved-in-mog-igg-versus-aqp4-igg-optic-neuritis-a-cohort-study
#19
Hadas Stiebel-Kalish, Itay Lotan, Judith Brody, Gabriel Chodick, Omer Bialer, Romain Marignier, Michael Bach, Mark Andrew Hellmann
BACKGROUND: Optic neuritis (ON) in patients with anti-myelin oligodendrocyte glycoprotein (MOG)-IgG antibodies has been associated with a better clinical outcome than anti-aquaporin 4 (AQP4)- IgG ON. Average retinal nerve fiber layer thickness (RNFL) correlates with visual outcome after ON. OBJECTIVES: The aim of this study was to examine whether anti-MOG-IgG ON is associated with better average RNFL compared to anti-AQP4-IgG ON, and whether this corresponds with a better visual outcome...
2017: PloS One
https://www.readbyqxmd.com/read/28124703/near-field-spectral-mapping-of-individual-exciton-complexes-of-monolayer-ws2-correlated-with-local-defects-and-charge-population
#20
Yongjun Lee, Seok Joon Yun, Youngbum Kim, Min Su Kim, Gang Hee Han, A K Sood, Jeongyong Kim
Exciton transitions are mostly responsible for the optical properties of transition metal dichalcogenide monolayers (1L-TMDs). Extensive studies of optical and structural characterization indicated that the presence of local structural defects and charge population critically influence the exciton emissions of 1L-TMDs. However, due to large variations of sample and experimental conditions, the exact mechanism of the exciton emission influenced by local structural defects and charge population is not clearly understood...
January 26, 2017: Nanoscale
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