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https://www.readbyqxmd.com/read/27916714/comparison-of-retinal-vessel-diameter-between-open-angle-glaucoma-patients-with-initial-parafoveal-scotoma-and-peripheral-nasal-step
#1
Eunjoo Yoo, Chungkwon Yoo, Tae-Eun Lee, Yong Yeon Kim
PURPOSE: To compare retinal vessel diameters (RVDs) between open-angle glaucoma (OAG) patients with initial parafoveal scotoma (PFS) and those with initial peripheral nasal step (PNS). DESIGN: Retrospective, cross-sectional study METHODS: We enrolled 151 eyes of 151 patients with OAG (83 with normal-tension glaucoma [NTG] and 68 with primary open-angle glaucoma [POAG]). The patients were categorized into the PFS and PNS groups according to the location of the initial visual field (VF) defect...
December 1, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27906070/subretinal-adipose-tissue-derived-mesenchymal-stem-cell-implantation-in-advanced-stage-retinitis-pigmentosa-a-phase-i-clinical-safety-study
#2
Ayse Oner, Z Burcin Gonen, Neslihan Sinim, Mustafa Cetin, Yusuf Ozkul
BACKGROUND: This prospective clinical case series aimed to investigate the safety of subretinal adipose tissue-derived mesenchymal stem cell (ADMSC) implantation in advanced stage retinitis pigmentosa (RP). METHODS: This study included 11 patients with end-stage RP who received subretinal implantation of ADMSCs. All patients had a total visual field defect and five of them only had light perception. The best corrected visual acuity (BCVA) in the study was 20/2000...
December 1, 2016: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/27898470/lamina-cribrosa-in-glaucoma
#3
J Crawford Downs, Christopher A Girkin
PURPOSE OF REVIEW: This article presents, summarizes, and interprets the most recent advances in the study and understanding of the lamina cribrosa in glaucoma, in the context of previous work. RECENT FINDINGS: The lamina is an active living structure that responds to strain by changing morphology at the micro-scale and macro-scale in glaucoma. Changes in lamina cribrosa morphology in glaucoma include posteriorization of the laminar insertion into the sclera, increased cupping or depth of the lamina cribrosa, and the development of focal lamina cribrosa defects...
November 25, 2016: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/27895794/trousseau-s-syndrome-caused-by-bladder-cancer-producing-granulocyte-colony-stimulating-factor-and-parathyroid-hormone-related-protein-a-case-report
#4
Tomonori Kato, Kenji Yasuda, Hiroaki Iida, Akihiko Watanabe, Yasuyoshi Fujiuchi, Shigeharu Miwa, Johji Imura, Akira Komiya
The present study reports a rare case of bladder cancer that caused Trousseau's syndrome, a malignancy-associated hypercoagulative state leading to venous or arterial thrombosis. A 38-year-old Japanese female patient experienced a sudden onset of visual field defects and lower limb weakness. Cerebral magnetic resonance imaging revealed multi-regional hypointense areas compatible with acute cerebral infarction. Despite the repeated administration of anticoagulant treatment with heparin, the condition could not be adequately controlled and thromboembolic events occasionally recurred...
November 2016: Oncology Letters
https://www.readbyqxmd.com/read/27888087/coiling-of-a-ruptured-large-internal-carotid-aneurysm-via-extracranial-intracranial-saphenous-vein-bypass-graft-just-after-proximal-ligation-of-the-internal-carotid-artery
#5
Hayato Tajima, Yoshio Araki, Takashi Izumi, Masahiro Nishihori, Sho Okamoto, Toshihiko Wakabayashi
BACKGROUND: Direct and endovascular combined surgery has been performed to treat large to giant internal carotid artery (ICA) aneurysms. This report describes successful treatment of the large ICA aneurysm by coiling of the aneurysm via extracranial-intracranial (EC-IC) saphenous vein graft (SVG) just after bypass and ICA proximal ligation. CASE DESCRIPTION: A 66-year-old woman presented with left ICA supraclinoid aneurysm with progressive visual field defect and impaired visual acuity in the left eye...
November 22, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27885957/visual-pathway-impairment-by-pituitary-adenomas-quantitative-diagnostics-by-diffusion-tensor-imaging
#6
Ylva Lilja, Oscar Gustafsson, Maria Ljungberg, Göran Starck, Bertil Lindblom, Thomas Skoglund, Henrik Bergquist, Karl-Erik Jakobsson, Daniel Nilsson
OBJECTIVE Despite ample experience in surgical treatment of pituitary adenomas, little is known about objective indices that may reveal risk of visual impairment caused by tumor growth that leads to compression of the anterior visual pathways. This study aimed to explore diffusion tensor imaging (DTI) as a means for objective assessment of injury to the anterior visual pathways caused by pituitary adenomas. METHODS Twenty-three patients with pituitary adenomas, scheduled for transsphenoidal tumor resection, and 20 healthy control subjects were included in the study...
November 25, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27872754/evaluation-of-contrast-sensitivity-chromatic-vision-and-reading-ability-in-patients-with-primary-open-angle-glaucoma
#7
Maria P Bambo, Blanca Ferrandez, Noemi Güerri, Isabel Fuertes, Beatriz Cameo, Vicente Polo, Jose M Larrosa, Elena Garcia-Martin
Purpose. To compare contrast sensitivity, acquired color vision deficiency, and reading ability in patients with glaucoma at different stages of the disease and to establish correlations between visual field parameters and visual function scores. Methods. This prospective cross-sectional study included 121 glaucoma patients. Subjects with a diagnosis of chronic open angle glaucoma were recruited and classified according to Hodapp-Parrish-Anderson criteria. Patients with severe visual field defects were excluded because they were older, which could bias the interpretation of visual function tests...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27862125/cases-of-advanced-visual-field-loss-at-referral-to-glaucoma-clinics-more-men-than-women
#8
David P Crabb, Luke J Saunders, Laura A Edwards
PURPOSE: In many medical conditions 'late presentation' of disease is more of a problem for men than women. Risk of sight loss from glaucoma is certainly greater in those detected with advanced disease. We performed a retrospective study to test the hypothesis that men are more likely than women to have advanced visual field loss at referral to glaucoma clinics. METHODS: We used 152 918 Humphrey visual fields from 32 147 patients from three regionally different hospitals in England; no other clinical data were made available apart from patient's age, sex and examination dates...
November 9, 2016: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/27861254/bilateral-diffuse-uveal-melanocytic-proliferation-associated-with-renal-cancer-the-importance-of-indocyanine-green-angiography-and-early-diagnosis
#9
Vinicius F Kniggendorf, Elmar T Neto, Elizabeth M Maia, Joao P S Grando, Anne M C Bardal, Patrícia M M Beato, Caroline C Torres, Mauricio Maia
PURPOSE: To report a case of bilateral diffuse uveal melanocytic proliferation associated with renal carcinoma and to illustrate the importance of ancillary examinations to early diagnosis and treatment. DESIGN: Clinical case report. METHODS: A 56-year-old man reported a 3-day history of visual impairment and scotoma in the right eye. An ophthalmoscopic examination, visual field test, fundus autofluorescence, fluorescein angiography, indocyanine green angiography, optical coherence tomography, and systemic evaluation were performed...
November 17, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27858936/retinal-ganglion-cell-and-axonal-loss-in-optic-neuritis-risk-factors-and-visual-functions
#10
T H Lee, Y S Ji, S W Park, H Heo
PurposeThe peripapillary retinal nerve fiber layer (pRNFL) and the macular ganglion cell-inner plexiform layer (GCIPL) are important predictive factors for the prognosis of optic neuritis (ON). We investigated the risk factors for pRNFL and GCIPL thinning in ON and its relationship with visual function.Patients and methodsWe analyzed 33 eyes of 33 patients with a first attack of unilateral ON. Patients were divided into two groups according to pRNFL and GCIPL thinning, using spectral-domain optical coherence tomography...
November 18, 2016: Eye
https://www.readbyqxmd.com/read/27857487/macular-thickness-assessment-in-patients-with-glaucoma-and-its-correlation-with-visual-fields
#11
Mafalda Mota, Fernando T Vaz, Mário Ramalho, Catarina Pedrosa, Maria Lisboa, Paulo Kaku, Florindo Esperancinha
AIM: To determine the relationship between macular thickness (MT) and visual field (VF) parameters, as well as with changes in the retinal nerve fiber layer (RNFL) thickness in patients with glaucoma and ocular hypertension (OH). MATERIALS AND METHODS: Cross-sectional statistical analysis of spectral domain optical coherence tomography (SD-OCT) compared with several VF parameters (mean defect - MD and loss variance - LV), in a nonrandom sample of 70 eyes from patients with glaucoma or OH...
September 2016: Journal of Current Glaucoma Practice
https://www.readbyqxmd.com/read/27851990/genetic-variants-associated-with-primary-open-angle-glaucoma-in-indian-population
#12
REVIEW
Sunil Kumar, Manzoor Ahmad Malik, Sooraj K, Ramanjit Sihota, Jasbir Kaur
Glaucoma is a very common disorder of the eye wherein the disturbance of the structural or functional integrity of the optic nerve causes characteristic atrophic changes in the optic nerve, which may lead to specific visual field defects over time. Primary open angle glaucoma (POAG) is most frequent among the three principle glaucoma subtypes. With well-established role of genes like Myocilin (MYOC), Optineurin (OPTN) and WD repeat Domain 36, (WDR36), at least 29 genetic loci have been found till date to be linked to POAG...
November 13, 2016: Genomics
https://www.readbyqxmd.com/read/27847689/a-comparison-of-perimetric-results-from-a-tablet-perimeter-and-humphrey-field-analyzer-in-glaucoma-patients
#13
Yu Xiang George Kong, Mingguang He, Jonathan G Crowston, Algis J Vingrys
PURPOSE: To determine the correlation between the perimetric outcomes from perimetry software Melbourne Rapid Fields (MRF) run on an Apple iPad tablet and those from the Humphrey Field Analyzer (HFA). METHODS: The MRF software was designed with features including variable fixation and fast thresholding using Bayes logic. Here, we report a cross-sectional study on 90 eyes from 90 participants: 12 had normal optic nerves and 78 had glaucoma with various degrees of visual field loss (41 mild and 37 moderate-severe)...
November 2016: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/27817914/enhanced-depth-imaging-optical-coherence-tomography-of-optic-nerve-head-drusen-a-comparison-of-cases-with-and-without-visual-field-loss
#14
Ghislaine L Traber, Konrad P Weber, Mazen Sabah, Pearse A Keane, Gordon T Plant
PURPOSE: Enhanced depth imaging (EDI) spectral-domain optical coherence tomography (SD OCT) has been recognized as the most sensitive tool to diagnose optic nerve head drusen (ONHD). The relationship between OCT characteristics and visual loss has not been well documented. This study compares EDI SD OCT-determined morphologic characteristics of drusen in eyes with or without visual field (VF) defects. DESIGN: Descriptive study of patients attending the neuro-ophthalmology service of Moorfields Eye Hospital between January 2013 and October 2014...
November 3, 2016: Ophthalmology
https://www.readbyqxmd.com/read/27813519/comparison-of-vision-related-quality-of-life-in-primary-open-angle-glaucoma-and-dry-type-age-related-macular-degeneration
#15
S Karadeniz Ugurlu, A E Kocakaya Altundal, M Altin Ekin
PurposeTo compare quality of life (QoL) in patients with primary open-angle glaucoma (POAG) and dry-type age-related macular degeneration (AMD) with similar best-corrected visual acuity.MethodsAge-, sex-, and visual acuity-matched POAG and dry AMD patients were included in the study. Each patient performed 24-2 and 10-2 SITA standard visual field tests. Contrast sensitivity was evaluated with CSV-1000 HGT instrument. The 25 item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) was used to analyze QoL...
November 4, 2016: Eye
https://www.readbyqxmd.com/read/27788273/correction-the-effects-of-compensatory-scanning-training-on-mobility-in-patients-with-homonymous-visual-field-defects-a-randomized-controlled-trial
#16
Gera A de Haan, Bart J M Melis-Dankers, Wiebo H Brouwer, Oliver Tucha, Joost Heutink
[This corrects the article DOI: 10.1371/journal.pone.0134459.].
2016: PloS One
https://www.readbyqxmd.com/read/27784274/preserved-retinal-sensitivity-in-spatial-correspondence-to-an-intrachoroidal-cavitation-area-with-full-thickness-retinal-defect-a-case-report
#17
Yoshiyuki Kita, Makoto Inoue, Gábor Hollό, Ritsuko Kita, Masahiko Sano, Akito Hirakata
BACKGROUND: Intrachoroidal cavitation (ICC) in the temporal peripapillary area is a relatively frequent finding in high myopia. However, ICC associated with a full thickness retinal defect rarely observed. We report an unusual case of ICC combined with a full thickness retinal defect in the papillo-macular bundle, in which the spatially corresponding visual field sensitivity was preserved. CASE PRESENTATION: A high myopic and pseudophakic left eye of a 79-year-old Japanese woman was evaluated with swept source optical coherence tomography (SS-OCT) and Humphrey 30-2 visual field testing for moderate glaucoma...
October 26, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27778456/parinaud-syndrome-a-25-year-1991-2016-review-of-40-consecutive-adult-cases
#18
Melissa Shields, Swati Sinkar, WengOnn Chan, John Crompton
PURPOSE: To characterize the clinical features, aetiology and management of ophthalmic symptoms in adult patients with Parinaud syndrome. METHODS: This is a retrospective, non-comparative observational case series. We reviewed 40 consecutive charts of adult patients with the clinical diagnosis of Parinaud syndrome at the Royal Adelaide Hospital Department of Ophthalmology in Adelaide, South Australia, between 1991 and 2016. Charts were reviewed for the following: (1) demographic information, (2) clinical presentation, (3) neuro-ophthalmology signs, (4) aetiology of Parinaud syndrome, and (5) management...
October 24, 2016: Acta Ophthalmologica
https://www.readbyqxmd.com/read/27778295/lymphocytic-hypophysitis-modern-day-management-with-limited-role-for-surgery
#19
Angelos Kyriacou, Kanna Gnanalingham, Tara Kearney
PURPOSE: We set out to describe the modern day management of Lymphocytic hypophysitis (LH) with respect to its diagnosis, treatment and long-term endocrine and visual outcomes. We deliberately included patients with a clinical diagnosis of LH and compared them with those with a histological diagnosis following surgery. METHODS: A multi-centre observational study was performed. Twenty-two patients were included and studied over a mean follow-up period of 8.6 years (range 4-26 years)...
October 24, 2016: Pituitary
https://www.readbyqxmd.com/read/27773906/lateral-geniculate-body-presenting-only-hemorrhage-homonymous-hemianopia-a-case-report
#20
Haruki Tokida, Yuhei Kanaya, Yutaka Shimoe, Shigeru Yamori, Koichi Tagawa, Masaru Kuriyama
We report a case of a 55-year-old man who developed acute-onset narrowing of his visual field. He showed right homonymous hemianopsia without any other neurological symptoms and signs. Brain CT and MRI showed localized hemorrhage (about 1.6 ml) in the left lateral geniculate body (LGB). A cerebral angiography showed no vascular anomalies of cerebral vessels, and the left anterior choroidal artery and left lateral posterior choroidal artery could be visualized well. He had hypertension, polycythemia and dyslipidemia and was a habitual smoker and an alcoholic...
November 29, 2016: Rinshō Shinkeigaku, Clinical Neurology
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