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https://www.readbyqxmd.com/read/28527279/-cases-of-acute-pesticide-poisoning-in-colonia-puerto-pirap%C3%A3-itap%C3%A3%C2%BAa-paraguay-february-2014
#1
María Esther Pedrozo, Sandra Ocampos, Rosa Galeano, Andrea Ojeda, Agueda Cabello, Dalva De Assis
In Paraguay, pesticides are the causative agent in 13.7% of poisonings, especially organophosphorus compounds. Such poisoning produces the inhibition of acetylcholinesterase generating three possible clinical conditions: acute poisoning, intermediate syndrome or late neurotoxicity. We present 15 cases of acute poisoning, ten women and five men from a rural community between 5 and 67 years of age, whose symptoms began after using water contaminated by pesticides from the community network. The most common symptoms were nausea and vomiting, followed by abdominal pain, headache, fever, itching, red eyes and sweating...
June 1, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/28521706/fibrinous-anterior-uveitis-and-recurrent-epithelial-erosion-following-topical-tetracaine-abuse
#2
Olga E Makri, Panagiotis Plotas, Foteini Tsapardoni, Ilias Georgalas, Constantinos D Georgakopoulos
A 54-year-old man presented complaining of severe pain and blurred vision in his left eye. Slit-lamp biomicroscopy revealed a large epithelial defect with an underlying prominent ring infiltrate and severe anterior uveitis with fibrinous exudates and hypopyon. Patient admitted abuse of topical tetracaine, which was discontinued and topical treatment with a non-steroidal anti-inflammatory agent, an antibiotic, a cycloplegic agent were instituted while a therapeutic contact lens was applied. Response to treatment was favorable with a rapid resolution of anterior uveitis within days while the epithelial defect fully healed within a month...
May 18, 2017: Current Drug Safety
https://www.readbyqxmd.com/read/28516471/topical-non-steroidal-anti-inflammatory-drugs-for-analgesia-in-traumatic-corneal-abrasions
#3
REVIEW
Abel Wakai, John G Lawrenson, Annali L Lawrenson, Yongjun Wang, Michael D Brown, Michael Quirke, Omar Ghandour, Ryan McCormick, Cathal D Walsh, Ahmed Amayem, Eddy Lang, Nick Harrison
BACKGROUND: Traumatic corneal abrasions are relatively common and there is a lack of consensus about analgesia in their management. It is therefore important to document the clinical efficacy and safety profile of topical ophthalmic non-steroidal anti-inflammatory drugs (NSAIDs) in the management of traumatic corneal abrasions. OBJECTIVES: To identify and evaluate all randomised controlled trials (RCTs) comparing the use of topical NSAIDs with placebo or any alternative analgesic interventions in adults with traumatic corneal abrasions (including corneal abrasions arising from foreign body removal), to reduce pain, and its effects on healing time...
May 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28516225/a-case-of-bilateral-keratitis-caused-by-providencia-alcalifaciens-a-rarely-encountered-ocular-pathogen
#4
Won Choi, Yong Sok Ji, Kyung Chul Yoon
PURPOSE: To report a case of keratitis caused by Providencia alcalifaciens. METHODS: A 70-year-old man presented with pain, redness, and decreased vision in both of his eyes. On initial presentation, the visual acuity in both of his eyes was hand motion, and slit lamp examination showed diffuse infiltrates and total epithelial defects of the cornea, conjunctival hyperemia, and severe anterior chamber reactions with 2-mm-height hypopyon. The results of laboratory studies revealed elevated liver function tests, which indicated the presence of alcoholic liver disease...
May 17, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28515032/bilateral-painless-testicular-mass-acute-uveitis-and-annular-cutaneous-lesions-an-unusual-presentation-of-sarcoidosis-and-literature-review
#5
Enver Şimşek, Tülay Şimşek, Meliha Demiral, Funda Canaz, M Fuat Açıkalın
BACKGROUND: Sarcoidosis is a systemic inflammatory disease characterized by non-caseating epitheloid granulomas; whereas it usually involves the lungs and lymph nodes, genitourinary involvement is extremely rare. For this reason, no consensus regarding the diagnostic and management options for testicular sarcoidosis has been reached. OBJECTIVE: The aim of this case report was to describe an unusual clinical presentation of sarcoidosis. An 8-year-old boy presented with a 6-month history of painless scrotal enlargement and a 2-month history of photophobia, blurred vision, and pain in both eyes...
May 17, 2017: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/28514833/antinociceptive-effect-of-%C3%AE-bisabolol-in-nanocapsules
#6
Gisele Façanha Diógenes Teixeira, Antonio Eufrásio Vieira-Neto, Flávio Nogueira da Costa, Angelo Roncalli Alves E Silva, Adriana Rolim Campos
This study aimed to develop and to evaluate the antinociceptive effect of a drug delivery system containing (-)-α-bisabolol (BISA). Nanocapsules containing BISA (BISA-NC) were prepared using acetylated galatomannan. Particle size distribution was determined by atomic force microscopy, zeta potential measurement and photon correlation spectroscopy. Corneal nociception was induced by topical application of 5M NaCl and the nociceptive behavior was characterized by eye wiping in mice. Molecular docking was conducted on the TRPV1 channel...
May 13, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28514361/-the-complications-of-transethmoidal-decompressive-orbitotomy-associated-with-endocrine-ophthalmopathy
#7
P A Kochetkov, Ya O Grusha, V M Svistushkin, S S Danilov
The objective of the present study was the analysis of the results of transethmoidal decompressive orbitotomy (TEDO) with the resection of the bone matrix of the medial and inferior orbital walls in the patients presenting with endocrine ophthalmopathy (EOP) with the purpose of reduction of the risk of development of this pathological conditions. A total of 51 patient with EOP at the stage of complete remission or pharmacotherapeutic compensation underwent transethmoidal decompressive medial orbitotomy in the ENT Clinic of 1 I...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28513499/role-of-mini-scleral-lens-in-mucous-membrane-pemphigoid
#8
Mukesh Kumar, Rohit Shetty, Chaitra Jayadev
This study aims to report the use of mini-scleral contact lens in the management of mucous membrane pemphigoid (MMP) with persistent epithelial defects. A 68-year-old male with a history of ocular pain and declining visual acuity was referred to our clinic with a diagnosis of MMP. His corrected distance visual acuity (CDVA) was 20/200 in the right eye and 20/100 in the left eye. Despite being on lubricants, topical steroids and intravenous cyclophosphamide, the patient developed persistent corneal epithelial defects in both eyes...
April 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28508918/-local-anaesthesia-in-ruminants
#9
Karl Nuss, Andrea Schwarz, Simone Ringer
The use of local anaesthesia in ruminants allows many surgical procedures to be conducted free of pain, efficiently and inexpensively in the field. Local anaesthesia combined with sedation and immobilisation of the animal can replace general anaesthesia for many procedures (e. g. castration, claw amputation). The level of difficulty differs among various local anaesthetic techniques: local infiltration of tissue or anaesthesia of the cornual nerve are easily performed, whereas local anaesthesia of the eye, regional anaesthesia in limbs or anaesthesia for umbilical surgery are more difficult to carry out...
May 16, 2017: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
https://www.readbyqxmd.com/read/28505350/evidence-of-altered-trigeminal-nociception-in-an-animal-model-of-fibromyalgia
#10
Masoud Nazeri, Mohammad-Reza Zarei, Amin-Reza Pourzare, Hamid-Reza Ghahreh-Chahi, Fatemeh Abareghi, Mohammad Shabani
Objective. : Fibromyalgia (FM) is a debilitating chronic condition that significantly affects quality of life. A strong association has been demonstrated between FM and chronic pain in the trigeminal region in clinical studies. This study was performed to evaluate the response to acute and chronic noxious stimuli applied to the facial region. Methods. : Adult male Wistar rats (250-270 g, N = 10 for each group) were used in the current study. A subchronic swim stress model was used as the animal model of FM...
May 13, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28503286/fulminant-hepatic-failure-due-to-metastatic-choroidal-melanoma
#11
Emmanuel Escobar-Valdivia, Roberto Monreal-Robles, Guillermo Delgado-García, Badir Hernández-Velazquez
BACKGROUND: Acute liver failure (ALF) as a consequence of metastatic disease is extremely uncommon. The liver is the most commonly affected organ by metastatic disease, but only a few cases of ALF in the setting of metastatic choroidal melanoma have been reported. CASE PRESENTATION: We describe the case of a 47-year-old man with right upper quadrant pain, progressive jaundice, and unintentional weight loss. He also reported that he had experienced reduced left visual acuity which progressed to blindness over 2 months...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28503064/combined-intrastromal-injection-of-amphotericin-b-and-topical-fluconazole-in-the-treatment-of-resistant-cases-of-keratomycosis-a-retrospective-study
#12
Waled Mahdy Nada, Mahmoud A Al Aswad, Wael M El-Haig
PURPOSE: To evaluate the efficacy of combination therapy of a single intrastromal injection of amphotericin B and topical fluconazole in resistant cases of fungal keratitis, and also topical amphotericin B as monotherapy in terms of the duration of the recovery period and toxic drug effects. METHODS: This retrospective 2-year study reviewed 68 cases of unilateral fungal keratitis diagnosed by clinical features and positive laboratory culture results. Forty-one cases were resistant and did not respond to monotherapy with an antifungal agent...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28502685/transorbital-glue-embolization-of-a-recurrent-venous-varix-using-real-time-image-guidance-in-the-neuroangiography-suite
#13
Sophia F Shakur, Denise Brunozzi, Pete Setabutr, Ahmed E Hussein, Fady T Charbel, Ali Alaraj
Orbital lesions are challenging to access due to their location amidst critical anatomical structures. Here, we demonstrate direct transorbital cannulation of an orbital venous varix using image guidance. A 36-year-old male was diagnosed to have a left orbital venous varix approximately 5 years ago at an outside institution. He subsequently underwent surgery for direct intraoperative embolization of the venous varix followed by surgical resection. The patient recently presented to us with left eye pain, proptosis, double vision, and conjunctival hemorrhage precipitated by straining or lying flat...
May 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28501097/orofacial-pain-and-headaches-associated-with-exfoliation-glaucoma
#14
Noboru Noma, Mayumi Iwasa, Andrew Young, Mariko Ikeda, Yung-Chu Hsu, Maasa Yamamoto, Kenji Inoue, Yoshiki Imamura
BACKGROUND AND OVERVIEW: Exfoliation syndrome is the most common identifiable cause of open-angle glaucoma. The authors report a case of exfoliation glaucoma in a patient who had orofacial pain. CASE DESCRIPTION: A 77-year-old woman was treated at the orofacial pain clinic for left-sided facial pain and headaches of 7 months' duration. Her cataracts and open-angle glaucoma had been diagnosed approximately 3 years earlier. Her main symptoms were orofacial pain, eye redness, inflammation of the eyelids, and eyelid edema...
May 11, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28499370/is-hydroxychloroquine-effective-in-treating-primary-sjogren-s-syndrome-a-systematic-review-and-meta-analysis
#15
Shi-Qin Wang, Li-Wei Zhang, Pan Wei, Hong Hua
BACKGROUND: To systematically review and assess the efficacy and safety of hydroxychloroquine (HCQ) for treating primary Sjogren's syndrome (pSS). METHODS: Five electronic databases (Pubmed, EMBASE, Web of science, Ovid, Cochrane Library) were searched for randomized controlled trials and retrospective or prospective studies published in English that reported the effect of HCQ on pSS. The subjective symptoms (sicca symptoms, fatigue and pain) and the objective indexes (erythrocyte sedimentation rate and Schirmer test) were assessed as main outcome measures...
May 12, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28498142/inflammatory-myopathy-and-axonal-neuropathy-in-a-patient-with-melanoma-following-pembrolizumab-treatment
#16
Panagiotis T Diamantopoulos, Katerina Tsatsou, Olga Benopoulou, Amalia Anastasopoulou, Helen Gogas
Immune-mediated adverse effects of immune checkpoint inhibitors are rather common, but neuromyopathic immune-related adverse events are very rare. In this report, we present a unique case of a patient with a complex neuromyopathic syndrome with axonal neuropathy and inflammatory myopathy after a single dose of pembrolizumab. An 82-year-old patient with a previously untreated stage IIIc melanoma developed ptosis in the left eye, generalized weakness, and neck and shoulder pain 15 days after pembrolizumab administration...
May 11, 2017: Journal of Immunotherapy
https://www.readbyqxmd.com/read/28492428/a-prospective-randomized-trial-comparing-plain-gut-to-polyglactin-910-vicryl-sutures-for-sclerotomy-closure-after-23-gauge-pars-plana-vitrectomy
#17
Jayanth Sridhar, Sundeep Kasi, Joshua Paul, Abtin Shahlaee, Ehsan Rahimy, Allen Chiang, Marc J Spirn, Jason Hsu, Sunir J Garg
PURPOSE: To report a prospective, randomized comparative study assessing clinical outcomes of plain gut versus polyglactin 910 (PG910) sutures for sclerotomy closure after 23-gauge pars plana vitrectomy. METHODS: A single-masked, randomized, prospective study was undertaken with 49 eyes of 49 patients undergoing 23-gauge pars plana vitrectomy randomized to sclerotomy closure with either plain gut suture, PG910 (Vicryl) suture or a combination of the two. Assessment was based on both a postoperative pain scale and a standardized assessment of scleral inflammation at each suture site...
May 10, 2017: Retina
https://www.readbyqxmd.com/read/28490477/bilateral-corneal-injury-after-face-paint-application-to-upper-eyelids
#18
Derek Kwun-Hong Ho, Ravi Ramessur, Sue Webber
A 40-year-old woman with no known medical conditions or allergies presented with severely painful, watery eyes and blurred vision. She reported topical application of face-paint onto both upper eyelids prior to attending a Halloween party. She subsequently noticed a burning sensation, epiphora and misty vision within a few hours. On examination, bilateral large corneal epithelial defects were highlighted with fluorescein dye under cobalt-blue light. Antibiotic ointment, mydriatic and sodium ascorbate 10% eye-drops were given, and patient was advised to keep the eyelids shut to promote healing...
May 10, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28489722/bilateral-herpetic-keratitis-after-bilateral-intravitreal-bevacizumab-for-exudative-macular-degeneration
#19
Angeline M Derham, Eric Chen, Vatinee Y Bunya, Ronan E OʼMalley
PURPOSE: To report a case of bilateral herpetic epithelial keratitis after bilateral intravitreal bevacizumab injections for the treatment of exudative age-related macular degeneration. METHODS: A 66-year-old man with diabetes and an extensive history of bilateral anti-vascular endothelial growth factor treatments for exudative age-related macular degeneration received an intravitreal bevacizumab injection in the right eye and triple therapy (bevacizumab, photodynamic therapy, and triamcinolone acetonide) in the left eye...
May 9, 2017: Cornea
https://www.readbyqxmd.com/read/28489642/pupillary-reflex-for-evaluation-of-thoracic-paravertebral-block-a-prospective-observational-feasibility-study
#20
Baptiste Duceau, Mélanie Baubillier, Gaëlle Bouroche, Aline Albi-Feldzer, Christian Jayr
BACKGROUND: Although thoracic paravertebral block (TPVB) is recommended in major breast surgery, there is no gold standard to assess the success of TPVB. Pupillary dilation reflex (PDR) is the variation of the pupillary diameter after a noxious stimulus. The objective was to evaluate the feasibility of recording the PDR to assess analgesia in an anesthetized thoracic dermatome after TPVB. METHODS: This prospective, observational, single-center study included 32 patients requiring breast surgery under general anesthesia and TPVB...
May 4, 2017: Anesthesia and Analgesia
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