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https://www.readbyqxmd.com/read/28719315/analysis-of-clinical-and-laboratory-alterations-related-to-dengue-case-severity-comparison-between-serotypes-2-and-4-in-brazil
#1
Nieli Rodrigues da Costa Faria, Victor Edgar Fiestas Solorzano, Luiz José de Souza, Rita Maria Ribeiro Nogueira, Fernanda de Bruycker-Nogueira, Thaís Chouin-Carneiro, Jaqueline Bastos Santos Simões, Monique da Rocha Queiroz Lima, Luzia Maria de Oliveira Pinto, Claire Fernandes Kubelka, Manoela Heringer, Elzinandes Leal de Azeredo, Flavia Barreto Dos Santos
The increase in severe dengue (SD) cases has caused great impact on public health and has concerned authorities of countries where the disease is endemic and epidemics reach high proportions. The recognition of progression signs of this severe disease during the initial febrile phase can be difficult, since the symptoms are often indistinguishable from other febrile diseases. The aim of this study was to evaluate the clinical manifestations and laboratory findings in patients from two dengue outbreaks and their association with the disease...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28706745/acute-esophageal-necrosis-in-an-alcoholic-after-successful-resuscitation-from-cardiac-arrest
#2
Amish Shah, Viveksandeep Thoguluva Chandreskar, Ravi Doobay, Arundeep Kahlon, Ioana Amzuta
INTRODUCTION: We present a patient who presented to the ICU after successful resuscitation from cardiac arrest who was subsequently diagnosed with AEN. CASE PRESENTATION: A 66-year-old female presented after cardiac arrest in which return of spontaneous circulation was achieved within 7 minutes after the initiation of CPR. She was intubated on the scene and found to have coffee ground emesis in her bathroom when found unresponsive. Due to the hemodynamically significant GI bleed, patient was started on IV proton pump inhibitor, octreotide, and levophed...
2017: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/28705921/apixaban-may-have-lower-risk-of-gi-bleeding-compared-with-dabigatran-and-rivaroxaban-in-patients-with-atrial-fibrillation
#3
José Miguel Rivera-Caravaca, Gregory Y H Lip
No abstract text is available yet for this article.
July 13, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28705401/-are-general-practitioners-in-paris-and-surrounding-areas-reticent-about-direct-oral-anticoagulants
#4
C Caucanas, D Sfeir, C Blas-Châtelain, P Priollet
OBJECTIVE: Determine how familiar general practitioners (GPs) working in Paris and surrounding areas are with prescriptions for direct oral anticoagulants (DOACs). MATERIAL AND METHOD: A questionnaire sent to 189 GP working in Paris and surrounding areas yielded 100 responses. Data collected included a brief summary of sociodemographic items, comparative knowledge about DOACs and vitamin K antagonists (VKAs), and responses to two clinical situations for DOAC prescriptions (renewal of a first prescription)...
May 2017: J Med Vasc
https://www.readbyqxmd.com/read/28704212/endoscopic-mucosal-resection-and-endoscopic-submucosal-dissection-technique-and-new-directions
#5
Toshihiro Nishizawa, Naohisa Yahagi
PURPOSE OF REVIEW: Most of small tumours in gastrointestinal tract are easily removed by endoscopic mucosal resection (EMR). However, EMR are sometimes not reliable to ensure the complete resection for large tumours. Although endoscopic submucosal dissection (ESD) was developed, it had a higher risk for complications such as perforation and bleeding. The techniques and clinical outcomes of EMR and ESD are reviewed. RECENT FINDINGS: ESD is more effective for early gastric and oesophageal cancer with higher en-bloc resection rate and lower local recurrence in comparison to EMR...
July 12, 2017: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/28703181/association-between-helicobacter-pylori-infection-and-long-term-outcome-in-patients-with-drug-eluting-stent-implantation
#6
Rui Wang, Lei-Lei Chen, De-Zhao Wang, Bu-Xing Chen
To investigate the relationship between Helicobacter pylori (Hp) infection and the long-term outcome in acute coronary syndrome (ACS) patients with drug-eluting stent (DES) implantation and so as to explore the significance of Hp eradication therapy in preventing major adverse cardiac events (MACE) and upper gastrointestinal bleeding (UGIB). 539 ACS patients with DES implantation from January 1, 2010 to December 31, 2012 were analyzed. All the patients were divided into two groups according to the result of (13)C urea breath test...
July 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28700711/non-vitamin-k-oral-anticoagulants-are-non-inferior-for-stroke-prevention-but-cause-fewer-major-bleedings-than-well-managed-warfarin-a-retrospective-register-study
#7
Vilhelm Sjögren, Björn Byström, Henrik Renlund, Peter J Svensson, Jonas Oldgren, Bo Norrving, Anders Själander
BACKGROUND: For patients with atrial fibrillation, non-vitamin K oral anticoagulants, or NOACs (dabigatran, rivaroxaban, edoxaban, and apixaban) have been proven non-inferior or superior to warfarin in preventing stroke and systemic embolism, and in risk of haemorrhage. In the pivotal NOAC studies, quality of warfarin treatment was poor with mean time in therapeutic range (TTR) 55-65%, compared with ≥70% in Swedish clinical practice. METHODS: We compared NOACs (as a group) to warfarin in non-valvular atrial fibrillation, studying all 12,694 patients starting NOAC treatment within the Swedish clinical register and dosing system Auricula, from July 1, 2011 to December 31, 2014, and matching them to 36,317 patients starting warfarin using propensity scoring...
2017: PloS One
https://www.readbyqxmd.com/read/28688221/minimal-factor-xiii-activity-level-to-prevent-major-spontaneous-bleeds
#8
M Menegatti, R Palla, M Boscarino, P Bucciarelli, L Muszbek, E Katona, M Makris, F Peyvandi
BACKGROUND: Congenital factor XIII (FXIII) deficiency is a rare bleeding disorder associated with significant bleeding manifestations. The European Network of Rare Bleeding Disorders (EN-RBD) study, performed from 2007 to 2010, showed a strong association between bleeding severity and FXIII activity in plasma of patients with FXIII deficiency. Among these patients variable levels of FXIII activity, from undetectable to 30%, were associated with a wide range of bleeding severity. Objectives and patients: The present cross-sectional study, in the frame of the PRO-RBDD project, a prospective cohort study, analyzed data of 64 patients with FXIII deficiency and different types of clinical and laboratory severity...
July 8, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28682563/-non-vitamin-k-dependent-oral-anticoagulants-noacs-in-chronic-kidney-disease-patients-with-non-valvular-atrial-fibrillation
#9
Luca Di Lullo, Vincenzo Barbera, Antonio Bellasi, Mario Cozzolino, Domenico Russo, Giovanni Otranto, Francesca Santoboni, Claudio Ronco
Atrial fibrillation (AF) represents the most common arrhythmia in patients with chronic kidney disease (CKD). As in the general population, AF is associated with an increased risk of thromboembolism and stroke, according to progressive decline of glomerular filtration rate (GFR). However, CKD patients, especially those on renal replacement therapy (RRT), also exhibit an increased risk of bleeding, especially from the gastrointestinal tract. Oral anticoagulation is the most effective form of thromboprophylaxis in patients with AF presenting increased risk of stroke...
April 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28682039/-noacs-and-chronic-kidney-disease
#10
Luca Di Lullo, Vincenzo Barbera, Antonio Bellasi, Mario Cozzolino, Domenico Russo, Giovanni Otranto, Francesca Santoboni, Claudio Ronco
Atrial fibrillation (AF) represents the most common arrhythmia in patients with chronic kidney disease (CKD). As in the general population, AF is associated with an increased risk of thromboembolism and stroke, according to progressive decline of glomerular filtration rate (GFR). However, CKD patients, especially those on renal replacement therapy (RRT), also exhibit an increased risk of bleeding, especially from the gastrointestinal tract. Oral anticoagulation is the most effective form of thromboprophylaxis in patients with AF presenting increased risk of stroke...
March 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28680709/the-antiplaque-and-bleeding-control-effects-of-a-cetylpyridinium-chloride-and-tranexamic-acid-mouth-rinse-in-patients-with-gingivitis
#11
Ji-Eun Lee, Jae-Mok Lee, Youngkyun Lee, Jin-Woo Park, Jo-Young Suh, Heung-Sik Um, Yong-Gun Kim
PURPOSE: This study aimed to evaluate the effects of a cetylpyridinium chloride (CPC) and tranexamic acid (TXA) mouth rinse on patients with gingivitis. METHODS: This randomized, placebo-controlled, double-blind, parallel-group, clinical trial included 45 healthy adults with gingivitis, who were randomized into 2 groups. The experimental group used a 0.05% CPC and 0.05% TXA mouth rinse, and the control group used a placebo mouth rinse. The following clinical indices were assessed at baseline, at 3 weeks, and at 6 weeks: the Turesky-Quigley-Hein plaque index (QHI), the Löe-Silness gingival index (GI), and bleeding on marginal probing (BOMP)...
June 2017: Journal of Periodontal & Implant Science
https://www.readbyqxmd.com/read/28670597/solitary-polypoid-angiodysplastic-lesion-mimicking-a-tumor-in-the-jejunum
#12
Abhishek D Polavarapu, Mayurathan Kesavan, Vivek V Gumaste, Monika Wrzolek, Elias Purow
Small bowel bleeding should be considered in patients with overt or occult gastrointestinal hemorrhage after normal upper and lower endoscopic examination. Angiodysplasia appearing as multiple flat vascular tufts is the most common cause of small bowel bleeding in patients over 40 years old. Polypoid angiodysplasia, however, is extremely rare. This report illustrates a unique case of solitary polypoid angiodysplasia in the jejunum of an adult with chronic kidney disease, who presented with an occult gastrointestinal bleed...
2017: ACG Case Reports Journal
https://www.readbyqxmd.com/read/28669702/incidence-and-prognostic-implications-of-late-bleeding-after-myocardial-infarction-or-unstable-angina-according-to-treatment-strategy
#13
Miriam Brinkert, Danielle A Southern, Matthew T James, Merrill L Knudtson, Todd J Anderson, François Charbonneau
BACKGROUND: Bleeding complications accompanying coronary revascularization are associated with increased mortality; however, few data are available on subsequent bleeding risk. We used administrative data to assess the incidence of late bleeding events in patients with acute coronary syndrome (ACS) according to treatment allocation. METHODS: The cohort and bleeding events were identified through the Canadian Institute for Health Information discharge abstract database...
May 5, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28668429/diagnosis-of-lower-gastrointestinal-bleeding-by-multi-slice-ct-angiography-a-meta-analysis
#14
Bosheng He, Jushun Yang, Jing Xiao, Jinhua Gu, Feixiang Chen, Lin Wang, Chengjin Zhao, Junbo Qian, Shenchu Gong
PURPOSE: To estimate the diagnostic value of multi-slice spiral CT angiography (CTA) in lower gastrointestinal bleeding by a meta-analysis. METHODS: The relevant clinical studies on the diagnostic value of CTA were searched on PubMed, Embase and other electronic documents databases with the deadline of 2016 September. Language was limited to English. A diagnostic meta-analysis was performed by using Meta-DiSc software. The effect sizes included sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), and diagnostic odds ratio (DOR) and 95% confidence interval (CI)...
August 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28666006/prevalence-of-and-risk-for-gastrointestinal-bleeding-and-peptic-ulcerative-disorders-in-a-cohort-of-hiv-patients-from-a-u-s-healthcare-claims-database
#15
Emily Bratton, Vani Vannappagari, Monica G Kobayashi
The primary study objectives were to estimate the frequencies and rates of gastrointestinal bleeding and peptic ulcerative disorder in HIV-positive patients compared with age- and sex-matched HIV-negative subjects. Data from a US insurance claims database was used for this analysis. Among 89,207 patients with HIV, 9.0% had a GI bleed, 1.0% had an upper gastrointestinal bleed, 5.6% had a lower gastrointestinal bleed, 1.9% had a peptic ulcerative disorder diagnosis, and 0.6% had both gastrointestinal/peptic ulcerative disorder...
2017: PloS One
https://www.readbyqxmd.com/read/28665206/primary-aorto-enteric-fistula-as-a-rare-cause-of-massive-gastrointestinal-haemorrhage
#16
Christian-Alexander Behrendt, Sabine Wipper, Sebastian E Debus, Yskert von Kodolitsch, Klaus Püschel, Michael Kammal, Anna Kammal
The incidence of primary aorto-enteric fistula (PAEF) is low with only few case reports and case series published. Depending on the location of the PAEF, the perforation leads to upper or lower gastrointestinal haemorrhages. We conducted a MEDLINE search according to the PRISMA statement. Articles with publication dates from 2000 to 2016 were included and present an own case report. We considered all case reports and series reporting on PAEF and identified 85 individual patients from 32 case reports and five case series...
June 30, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28656336/multicenter-evaluation-of-first-line-endoscopic%C3%A2-treatment%C3%A2-with-the%C3%A2-otsc-in-acute-non-variceal-upper-gastrointestinal%C3%A2-bleeding-and-comparison-with-the-rockall-cohort-the-fletrock-study
#17
E Wedi, A Fischer, J Hochberger, C Jung, S Orkut, H J Richter-Schrag
INTRODUCTION: The over-the-scope clip (OTSC) overcomes limitations of standard clips and achieves a more efficient and reliable hemostasis in non-variceal upper gastrointestinal bleeding (NVUGIB). The study aims to evaluate mortality, rebleeding, and mortality after rebleeding of patients in whom the OTSC was used as the first-line endoscopic treatment (FLET) of NVUGIB. PATIENTS AND METHODS: In total, 118 patients (FLET cohort) with a median age of 73.5 years (range 29-93 years; mean (±SD) 71...
June 27, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28651935/derivation-and-validation-of-a-novel-risk-score-for-safe-discharge-after-acute-lower-gastrointestinal-bleeding-a-modelling-study
#18
Kathryn Oakland, Vipul Jairath, Raman Uberoi, Richard Guy, Lakshmana Ayaru, Neil Mortensen, Mike F Murphy, Gary S Collins
BACKGROUND: Acute lower gastrointestinal bleeding is a common reason for emergency hospital admission, and identification of patients at low risk of harm, who are therefore suitable for outpatient investigation, is a clinical and research priority. We aimed to develop and externally validate a simple risk score to identify patients with lower gastrointestinal bleeding who could safely avoid hospital admission. METHODS: We undertook model development with data from the National Comparative Audit of Lower Gastrointestinal Bleeding from 143 hospitals in the UK in 2015...
June 23, 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28651934/embracing-early-discharge-in-patients-with-lower-gastrointestinal-bleeding
#19
Neil Sengupta, Elliot B Tapper
No abstract text is available yet for this article.
June 23, 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28645954/assessing-the-impact-of-colonoscopy-complications-on-use-of-colonoscopy-among-primary-care-physicians-and-other-connected-physicians-an-observational-study-of-older-americans
#20
Nancy L Keating, A James O'Malley, Jukka-Pekka Onnela, Bruce E Landon
OBJECTIVES: Psychological biases can distort treatment decision-making. The availability heuristic is one such bias, wherein events that are recent, vivid or easily imagined are readily 'available' to memory and are therefore judged more likely to occur than expected based on epidemiological data. We assessed if the occurrence of a serious colonoscopy complication for a primary care physician's patient influenced colonoscopy rates for the physician's other patients. DESIGN: Longitudinal study with time-varying exposure variables...
June 23, 2017: BMJ Open
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