keyword
https://read.qxmd.com/read/38228105/shared-neuroanatomical-substrates-for-co-occurring-swallowing-and-communication-impairments-after-acute-stroke
#1
Heather Flowers, David Mikulis, Frank Silver, Kannika Hour, Jason Steffener, Julien Poublanc, Elizabeth Rochon, Rosemary Martino
INTRODUCTION: Post-stroke dysphagia and communication impairments occur in two-thirds of acute stroke survivors. Identifying the shared neuroanatomical substrate for related impairments could facilitate the development of cross-system therapies. Our purpose was to elucidate discrete brain regions predictive of the combined presence of dysphagia alongside dysarthria and/or aphasia post-stroke. METHODS: We included 40 right (RHS) and 67 left hemisphere (LHS) patients from an acute ischemic stroke cohort with lesions demarcated on diffusion weighted imaging...
January 16, 2024: Cerebrovascular Diseases
https://read.qxmd.com/read/38193360/role-of-the-repeat-expansion-size-in-predicting-age-of-onset-and-severity-in-rfc1-disease
#2
JOURNAL ARTICLE
Riccardo Currò, Natalia Dominik, Stefano Facchini, Elisa Vegezzi, Roisin Sullivan, Valentina Galassi Deforie, Gorka Fernández-Eulate, Andreas Traschütz, Salvatore Rossi, Matteo Garibaldi, Mariusz Kwarciany, Franco Taroni, Alfredo Brusco, Jean-Marc Good, Francesca Cavalcanti, Simon Hammans, Gianina Ravenscroft, Richard H Roxburgh, Ricardo Parolin Schnekenberg, Bianca Rugginini, Elena Abati, Arianna Manini, Ilaria Quartesan, Arianna Ghia, Adolfo Lòpez de Munaìn, Fiore Manganelli, Marina Kennerson, Filippo Maria Santorelli, Jon Infante, Wilson Marques, Manu Jokela, Sinéad M Murphy, Paola Mandich, Gian Maria Fabrizi, Chiara Briani, David Gosal, Davide Pareyson, Alberto Ferrari, Ferran Prados, Tarek Yousry, Vikram Khurana, Sheng-Han Kuo, James Miller, Claire Troakes, Zane Jaunmuktane, Paola Giunti, Annette Hartmann, Nazli Basak, Matthis Synofzik, Tanya Stojkovic, Marios Hadjivassiliou, Mary M Reilly, Henry Houlden, Andrea Cortese
RFC1 disease, caused by biallelic repeat expansion in RFC1, is clinically heterogeneous in terms of age of onset, disease progression and phenotype. We investigated the role of the repeat size in influencing clinical variables in RFC1 disease. We also assessed the presence and role of meiotic and somatic instability of the repeat. In this study, we identified 553 patients carrying biallelic RFC1 expansions and measured the repeat expansion size in 392 cases. Pearson's coefficient was calculated to assess the correlation between the repeat size and age at disease onset...
January 9, 2024: Brain
https://read.qxmd.com/read/38164540/disconnection-based-prediction-of-poststroke-dysphagia
#3
JOURNAL ARTICLE
Kyung Jae Yoon, Chul-Hyun Park, Myung-Ho Rho, Minchul Kim
BACKGROUND AND PURPOSE: Dysphagia is a common deficit after a stroke and is associated with serious complications. It is not yet fully clear which brain regions are directly related to swallowing. Previous lesion symptom mapping studies may have overlooked structural disconnections that could be responsible for poststroke dysphagia. Here, we aimed to predict and explain the relationship between poststroke dysphagia and the topologic distribution of structural disconnection via a multivariate predictive framework...
December 21, 2023: AJNR. American Journal of Neuroradiology
https://read.qxmd.com/read/38156085/research-trends-and-hotspots-of-post-stroke-dysphagia-rehabilitation-a-bibliometric-study-and-visualization-analysis
#4
REVIEW
Yuanyuan He, Xuezeng Tan, Huiqi Kang, Huan Wang, Yuyao Xie, Dongxiang Zheng, Chen Li
BACKGROUND: Post-stroke dysphagia (PSD) is one of the most prevalent stroke sequelae, affecting stroke patients' prognosis, rehabilitation results, and quality of life while posing a significant cost burden. Although studies have been undertaken to characterize the pathophysiology, epidemiology, and risk factors of post-stroke dysphagia, there is still a paucity of research trends and hotspots on this subject. The purpose of this study was to create a visual knowledge map based on bibliometric analysis that identifies research hotspots and predicts future research trends...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37638456/diffusion-tensor-imaging-magnetic-resonance-imaging-dti-mri-helps-to-tailor-speech-therapy-a-case-report-with-a-short-narrative-review
#5
REVIEW
Di Lorenzo Luigi, Franco Carmine Muccio
BACKGROUND: Stroke has functional sequelae, including motor weakness, spasticity, dysphagia, and neurogenic bladder deteriorating activities of daily living. Speech therapy is more often an essential part of the rehabilitation program. Studies in aphasia have primarily focused on two major pathways: the arcuate fasciculus and the superior longitudinal fasciculus. The arcuate fasciculus is a major fiber bundle connecting Broca's area (associated with language production) and Wernicke's area (associated with language comprehension)...
2023: NeuroRehabilitation
https://read.qxmd.com/read/37535137/clinical-features-and-voxel-based-symptom-lesion-mapping-of-silent-aspiration-in-acute-infratentorial-stroke
#6
JOURNAL ARTICLE
H Lesch, M Wittayer, M Dias, A Nick, A Ebert, P Eisele, A Alonso
Post-stroke dysphagia (PSD) is a severe and common complication after ischemic stroke. The role of silent aspiration as an important contributing factor in the development of a dysphagia-associated complications, in particular aspiration-associated pneumonia has been insufficiently understood. The aim of this study was to investigate the characteristics and risk factors of silent aspiration in patients with acute infratentorial stroke by FEES and to identify culprit lesions in stroke patient with a high risk of silent aspiration via voxel-based-symptom-lesion mapping (VBS/ML)...
August 3, 2023: Dysphagia
https://read.qxmd.com/read/37041694/association-of-dysphagia-with-altered-brain-glucose-metabolism-in-parkinson-s-disease
#7
JOURNAL ARTICLE
Ji Yeon Oh, Eui Jin An, Young Lee, Seung Min Kim, Miju Cheon, Jun Yup Kim
AIMS: Dysphagia is a major clinical concern in Parkinson's disease (PD). However, the relationship between the development of phase-specific dysphagia and the regional brain glucose metabolism remains unclear. Our objective was to investigate the distributions of brain glucose metabolism specific to oral and pharyngeal phases of dysphagia in PD. METHODS: In this retrospective cross-sectional study, patients with PD who underwent videofluoroscopic swallowing study (VFSS) and 18 F-fluorodeoxy-glucose positron emission tomography at intervals of <1 month were included...
April 11, 2023: CNS Neuroscience & Therapeutics
https://read.qxmd.com/read/36607363/striatal-dopaminergic-loss-and-dysphagia-in-parkinson-disease
#8
JOURNAL ARTICLE
Ji Hwan Kim, Jonghu Jeon, Young Lee, Seung Min Kim, Miju Cheon, Jun Yup Kim
PURPOSE: To better understand the development of dysphagia in patients with Parkinson disease (PD) and to identify possible neuromodulatory target regions of dysphagia, we studied the striatal dopamine transporter (DAT) availability distribution by subtype of dysphagia. METHODS: In this retrospective cross-sectional study, patients with PD who underwent videofluoroscopic swallowing study and N-(3-[18F]fluoropropyl)-2β-carbon ethoxy-3β-(4-iodophenyl) nortropane (18F-FP-CIT) PET at intervals of less than 1 month were analyzed...
February 1, 2023: Clinical Nuclear Medicine
https://read.qxmd.com/read/36301361/clinical-and-imaging-predictors-of-dysphagia-and-swallowing-ability-recovery-in-acute-ischemic-stroke
#9
JOURNAL ARTICLE
Xiao Hu, Mingjun Pu, Zijie Wang, Jialun Yu, Xiaofang Wu, Jing Cheng, Chu Chen, Hao Yin, Tiannan Yang, Zhehao Zhang, Libo Zhao, Peng Xie, Qi Li
OBJECTIVE: Dysphagia is one of the most common complications of acute ischemic stroke, and prediction of dysphagia is crucial for post-stroke treatment. We aimed to identify predictors of dysphagia and swallowing function recovery following ischemic stroke and to investigate dysphagia-associated lesion location. METHODS: We prospectively enrolled patients with acute ischemic stroke confirmed on diffusion-weighted imaging. All patients received swallowing evaluation within 48 h after admission...
October 27, 2022: Neurological Sciences
https://read.qxmd.com/read/35772193/swallowing-function-in-the-chronic-stage-following-stroke-is-associated-with-white-matter-integrity-of-the-callosal-tract-between-the-interhemispheric-s1-swallowing-representation-areas
#10
JOURNAL ARTICLE
M Domin, G P Mihai, T Platz, M Lotze
Sensorimotor representations of swallowing in pre- and postcentral gyri of both cerebral hemispheres are interconnected by callosal tracts. We were interested in (1) the callosal location of fibers interconnecting the precentral gyri (with the primary motor cortex; M1) and the postcentral gyri (with the primary somatosensory cortex; S1) relevant for swallowing, and (2) the importance of their integrity given the challenges of swallowing compliance after recovery of dysphagia following stroke. We investigated 17 patients who had almost recovered from dysphagia in the chronic stage following stroke and age-matched and gender-matched healthy controls...
2022: NeuroImage: Clinical
https://read.qxmd.com/read/35388042/excitatory-neurons-in-paraventricular-hypothalamus-contributed-to-the-mechanism-underlying-acupuncture-regulating-the-swallowing-function
#11
JOURNAL ARTICLE
Si Yuan, Bing Deng, Qiuping Ye, Zhennan Wu, Junshang Wu, Lin Wang, Qin Xu, Lulu Yao, Nenggui Xu
Paraventricular hypothalamus (PVH) is demonstrated to regulate stress, feeding behaviors, and other related homeostatic processes. However, no direct evidence has been investigated for the role of PVH in swallowing function. Acupuncture therapy at Lianquan (CV23) acupoint has been reported to improve the swallowing function in clinical trials, but its underlying mechanism still needs to be uncovered. Thus, we aimed to explore whether PVH involved the acupuncture mediated regulating swallowing function. Chemogenetics, electromyography (EMG) recording, and immunofluorescence staining methods were combined to demonstrate that neurons in PVH could be activated by electroacupuncture (EA) stimulation at CV23, and this neuronal cluster was represented as excitatory neurons...
April 6, 2022: Scientific Reports
https://read.qxmd.com/read/34903269/dysphagia-rehabilitation-following-acquired-brain-injury-including-cerebral-palsy-across-the-lifespan-a-scoping-review-protocol
#12
JOURNAL ARTICLE
Rhiannon Halfpenny, Alexandra Stewart, Paula Kelly, Eleanor Conway, Christina Smith
BACKGROUND: Swallowing impairment (dysphagia) following brain injury can lead to life-threatening complications such as dehydration, aspiration pneumonia and acute choking episodes. In adult therapeutic practice, there is research and clinical evidence to support the use of swallowing exercises to improve swallowing physiology in dysphagia; however, the use of these exercises in treating children with dysphagia is largely unexplored. Fundamental questions remain regarding the feasibility and effectiveness of using swallowing exercises with children...
December 13, 2021: Systematic Reviews
https://read.qxmd.com/read/34857571/scoping-review-to-identify-and-map-non-pharmacological-non-surgical-treatments-for-dysphagia-following-moderate-to-severe-acquired-brain-injury
#13
REVIEW
Signe Janum Eskildsen, Ingrid Poulsen, Daniela Jakobsen, Christian Gunge Riberholt, Derek John Curtis
INTRODUCTION: Dysphagia is a common and critical consequence of acquired brain injury (ABI) and can cause severe complications. Dysphagia rehabilitation is transforming from mainly compensatory strategies to the retraining of swallowing function using principles from neuroscience. However, there are no studies that map interventions available to retrain swallowing function in patients with moderate-to-severe ABI. OBJECTIVE: To systematically map the accessible research literature to answer the research question: Which non-surgical, non-pharmacological interventions are used in the treatment of dysphagia in patients with moderate and severe ABI in the acute and subacute phase? DESIGN: Scoping review based on the methodology of Arksey and O'Malley and methodological advancement by Levac et al...
December 2, 2021: BMJ Open
https://read.qxmd.com/read/34773172/voxel-based-lesion-symptom-mapping-analysis-for-dysphagia-in-stroke-patients-with-isolated-cerebellar-lesions
#14
JOURNAL ARTICLE
Hyun Im Moon, Yoon Jeong Jeong, Ji Hyun Suh
Because the cerebellum plays a role in motor coordination, timing, sequencing, and feedback, it is hypothesized to be involved in swallowing-related functions. The role of the cerebellum in deglutition has become increasing evident, but the exact nature of this role remains inconclusive because of limited data from pure cerebellar lesions. Therefore, we conducted location analysis in isolated cerebellar lesions to complement previous findings and provide additional information. We reviewed 40 stroke patients with isolated cerebellar lesion...
November 12, 2021: Journal of Neural Transmission
https://read.qxmd.com/read/34762204/structural-connectivity-affecting-aspiration-after-stroke
#15
JOURNAL ARTICLE
Hea Eun Yang, Hyunkoo Kang, Sohyon Kyeong, Dae Hyun Kim
Aspiration after stroke is associated with pneumonia and mortality. In this study, we investigated brain structural connectivity associated with aspiration after unilateral supratentorial stroke. Patients on oral feeding after stroke were divided into liquid aspiration (22 patients) and normal (18 patients) groups based on videofluoroscopic swallowing studies. Voxel-based lesion-symptom mapping and voxel-wise group comparison of fractional anisotropy, mode of anisotropy, and mean diffusivity maps were conducted...
October 2022: Dysphagia
https://read.qxmd.com/read/34744695/predictive-model-of-dysphagia-and-brain-lesion-symptom-mapping-in-acute-ischemic-stroke
#16
JOURNAL ARTICLE
Lulu Zhang, Xiang Tang, Can Wang, Dongxue Ding, Juehua Zhu, Yun Zhou, Shanshan Diao, Yan Kong, Xiuying Cai, Cuiping Li, Ye Yao, Qi Fang
Background and purpose: Early recognition and management of post-stroke dysphagia (PSD) based on MRI may reduce the incidence of complications. Combining clinical symptoms with applications of MRI, we aimed to identify the risk factors of PSD, develop a prediction scale with high accuracy and map key dysphagia brain areas. Methods: A total of 275 acute ischemic stroke patients were enrolled in this study, and 113 (41.1%) patients were diagnosed with PSD. All patients underwent the water-swallowing test (WST) and volume-viscosity swallow test (V-VST) within first 24 h following admission to assess swallowing...
2021: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/34000833/association-of-lesion-pattern-and-dysphagia-in-acute-intracerebral-hemorrhage
#17
JOURNAL ARTICLE
Felix Hess, Christian Foerch, Fee Keil, Alexander Seiler, Sriramya Lapa
Background and Purpose: Dysphagia is a common and severe symptom of acute stroke. Although intracerebral hemorrhages (ICHs) account for 10% to 15% of all strokes, the occurrence of dysphagia in this subtype of stroke has not been widely investigated. The aim of this study was to evaluate the overall frequency and associated lesion locations and clinical predictors of dysphagia in patients with acute ICH. Methods: Our analysis included 132 patients with acute ICH...
August 2021: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/31320355/protocol-for-a-scoping-review-study-to-identify-and-map-treatments-for-dysphagia-following-moderate-to-severe-acquired-brain-injury
#18
JOURNAL ARTICLE
Signe Janum Eskildsen, Daniela Jakobsen, Christian Gunge Riberholt, Ingrid Poulsen, Derek John Curtis
INTRODUCTION: Dysphagia is highly prevalent in patients with acquired brain injury (ABI) and is associated with high morbidity and mortality. However, dysphagia management varies greatly between units and internationally, and there is currently no consensus, standard intervention or treatment. A review mapping the existing literature on dysphagia treatment is needed. In this paper, the protocol for a scoping review to identify and map dysphagia treatment following ABI is outlined. OBJECTIVE: The objective of the scoping review is to systematically map the existing research literature to answer the research question: Which non-surgical, non-pharmacological interventions are used in the treatment of dysphagia in patients with moderate and severe acquired brain injury in the acute and subacute phase? METHODS AND ANALYSIS: The methodological framework for the study is based on methodology by Arksey and O'Malley and methodological advancement by Levac et al ...
July 17, 2019: BMJ Open
https://read.qxmd.com/read/30711683/mapping-acute-lesion-locations-to-physiological-swallow-impairments-after-stroke
#19
JOURNAL ARTICLE
Janina Wilmskoetter, Leonardo Bonilha, Bonnie Martin-Harris, Jordan J Elm, Janet Horn, Heather S Bonilha
Dysphagia is a common deficit after a stroke, and it is frequently associated with pneumonia, malnutrition, dehydration, and poor quality of life. It is not yet fully clear which brain regions are directly related to swallowing, and how lesions affect swallow physiology. This study aimed to assess the statistical relationship between acute stroke lesion locations and impairment of specific aspects of swallow physiology. We performed lesion symptom mapping with 68 retrospectively recruited, acute, first-ever ischemic stroke patients...
2019: NeuroImage: Clinical
https://read.qxmd.com/read/30688391/a-pilot-study-of-the-effects-of-high-frequency-repetitive-transcranial-magnetic-stimulation-on-dysphagia-in-the-elderly
#20
JOURNAL ARTICLE
Jin-Woo Park, Hyojun Kim, Taejune Park, Jeong-Seok Yeo, Ho-Jin Hong, Jin-Young Oh
BACKGROUND: Swallowing difficulty is common in the geriatric population and is associated with brain activity alteration with advancing age. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive approach to stimulate cortical neurons and can produce changes in cortical excitability. The objective of this study is to determine whether rTMS induces positive changes in the cortical areas and facilitates swallowing function in the elderly diagnosed with dysphagia. METHODS: Eight right-handed elderly dysphagia patients without any neurologic deficits received 5 Hz rTMS to a pharyngeal motor hot spot in the right hemisphere for 10 minutes every weekday for 2 weeks...
May 2019: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
keyword
keyword
72638
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.