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https://www.readbyqxmd.com/read/28432540/preliminary-clinical-study-on-non-transecting-anastomotic-bulbomembranous-urethroplasty
#1
Wei Le, Chao Li, Jinfu Zhang, Denglong Wu, Bo Liu
This study aims to investigate the effect of non-transecting anastomotic urethroplasty for treatment of posterior urethral stricture. A total of 23 patients with traumatic posterior urethral stricture were enrolled and then divided into two groups. In one group, 12 patients underwent non-transecting anastomotic urethroplasty. In the other group, 11 patients underwent conventional posterior urethra end-to-end anastomosis. The effect of operation was evaluated using the following parameters: the bleeding amount during operation, operation time, IIEF-5 scores after operation, maximum flow rate (Qmax), and rating scale of quality of life (QoL)...
April 22, 2017: Frontiers of Medicine
https://www.readbyqxmd.com/read/28429926/the-efficacy-of-intraurethral-lidocaine-in-optical-internal-urethrotomy-for-anterior-urethral-stricture-a-multicenter-study
#2
Nedim Y Cem, Yıldız Yildiray, Cem Ö Berat, Melih S Mehmet, Gökhan D Ömer, Metin H Ahmet, Özyuvalı Ekrem, Ayyıldız Ali
BACKGROUND: Male anterior urethral strictures can be treated successfully with the help of optical internal urethrotomy (OIU) and is usually performed under general or regional anaesthesia. In this study, we determined the efficacy of intraurethral lidocaine in OIU for anterior urethral stricture in an outpatient setting. METHODS: 157 patients with anterior urethral strictures underwent OIU under local urethral anaesthesia with lidocaine. Optical urethrotomy was performed with a cold-cutting knife...
April 20, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/28424371/comprehensive-assessmentof-cavernosography-with-320-row-dynamic-volume-ct-versus-conventional-cavernosography-in-erectile-dysfunction-patients-caused-by-venous-leakage
#3
Cheng-Cheng Xu, Yu-Ning Pan, Yi-Fan Tang, Jie Zhang, Guo-Yao Wang, Qiu-Li Huang
This study aims to investigate and compare the diagnostic and prognostic value of cavernosography with 320-row dynamic volume computed tomography (DVCT) versus conventional cavernosography in men with erectile dysfunction (ED) caused by venous leakage. A total of 174 patients diagnosed with ED were enrolled and received cavernosography with 320-row DVCT (DVCT group) and conventional cavernosography scans (control group), respectively. The diagnosis, complications and prognosis of patients were evaluated. The DVCT group provided higher-resolution images with less processing and testing time, as well as lowered does radiological agent and contrast agent compared to the control group...
April 19, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28417077/direct-extension-of-prostatic-adenocarcinoma-protruding-through-the-urethral-meatus
#4
Hasan Jhaveri, Kristen Combs, Faiyaaz Jhaveri
Prostate cancer involving the anterior urethra is rare with few cases describing isolated recurrence to the anterior urethra. This case describes a patient with a history of metastatic prostate cancer who subsequently developed advanced prostate cancer involving the entire urethra with extension from the prostatic urethra to the urethral meatus. This will help future healthcare providers recognize this metastatic pattern as a possibility and explore this option when presented with a bleeding mass at the urethral meatus of unknown origin...
July 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28413305/solitary-functioning-kidney-in-high-anorectal-malformation
#5
Kanishka Das, Srinivas Raju Rajkiran
AIM: A solitary functioning renal unit in high anorectal malformation may harbor anomalies in the upper/lower urinary tract that further compromise renal function and accelerate hyperfiltration injury. We aimed to analyze the clinical course, management, and outcome of children with a solitary renal unit and high anorectal malformation. MATERIALS AND METHODS: A cohort of solitary renal units in anorectal malformation managed between 2000 and 2015 with a defined protocol at a pediatric nephro-urology clinic are included in the study...
April 2017: Journal of Indian Association of Pediatric Surgeons
https://www.readbyqxmd.com/read/28413299/congenital-pouch-colon
#6
REVIEW
Rajiv Chadha, Niyaz Ahmed Khan
Congenital pouch colon (CPC) is an unusual abnormality in which a pouch-like dilatation of a shortened colon is associated with an anorectal malformation. It is categorized into four subtypes (Types I-IV) based on the length of normal colon proximal to the colonic pouch. In males, the pouch usually terminates in a colovesical fistula just proximal to the bladder neck. In girls, the terminal fistula opens either into the urethra or in the vestibule, close to the urethral opening. Girls usually have a double vagina with a wide inter-vaginal bridge, a monocornuate uterus on each side, and urinary incontinence due to a widely open bladder neck...
April 2017: Journal of Indian Association of Pediatric Surgeons
https://www.readbyqxmd.com/read/28412134/clinical-courses-of-herpes-simplex-virus-induced-urethritis-in-men
#7
Shin Ito, Mitsuru Yasuda, Hiromi Kondo, Yoshiteru Yamada, Keita Nakane, Kosuke Mizutani, Tomohiro Tsuchiya, Shigeaki Yokoi, Masahiro Nakano, Takashi Deguchi
We retrieved clinical data of 13 men having herpes simplex virus (HSV)-induced non-gonococcal urethritis (NGU) without visible herpetic lesions. They visited a clinic in Sendai, Japan, between April 2013 and December 2015. All the men complained of dysuria. Meatitis was observed in 9 of the 13 men. Mononuclear cells were observed in the urethral smears from 9 men. The 13 men were treated with azithromycin or sitafloxacin regimen. First-voided urine (FVU) specimens became negative for HSV in 8 of the 10 men who returned to the clinic after antibacterial treatment, and urethritis symptoms were alleviated...
April 12, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28407305/female-striated-urogenital-sphincter-contraction-measured-by-shear-wave-elastography-during-pelvic-floor-muscle-activation-proof-of-concept-and-validation
#8
Rafeef Aljuraifani, Ryan E Stafford, François Hug, Paul W Hodges
AIMS: Investigation of the function of the striated urogenital sphincter (SUS) is challenging because it is difficult to access and requires invasive measures. Ultrasound shear wave elastography (SWE) is a non-invasive real-time technique used to estimate tissue stiffness. As muscle stiffness can be used as an estimate of muscle force, SWE provides an opportunity to study contraction of the peri-urethral musculature. Validation of SWE to study SUS during functional tasks, such as pelvic floor muscle contractions, is required prior to application in clinical populations...
April 13, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28403494/-macrohaematuria-in-children
#9
Franziska E Müller-Semaan, Stefan C Müller
Urethritis posterior is a possible cause of asymptomatic haematuria in prepubescent boys. It is a benign lesion of the posterior urethra and its cardinal symptoms are blood spots in the underwear without any laboratory or radiologic findings. Urethrocystoscopy is the only way to confirm the diagnosis, but has been subject to criticism as it is associated with a high risk of strictures. It is advisable to adopt a "wait and see" strategy because urethritis posterior usually heals spontaneously over time. This condition is most likely caused by detrusor-sphincter dyssynergia, since behavioural intervention with biofeedback therapy offers good treatment results...
February 2017: Aktuelle Urologie
https://www.readbyqxmd.com/read/28401037/female-epispadias-presenting-as-urinary-incontinence
#10
Asmir Jonuzi, Nusret Popovic, Zlatan Zvizdic, Emir Milišic, Kenan Karavdic, Dewan Paddy
Isolated female epispadias without bladder exstrophy is a rare congenital anomaly affecting 1 in 484,000 females. The presenting features of female epispadias are urinary incontinence and abnormal anatomical features. A 6-year-old girl presented with primary urinary incontinence who on physical examination had a bifid clitoris and labia minora. The vagina and hymen were normal. Voiding cystourethrogram showed no reflux and a funnel shaped proximal urethra. With the diagnosis of isolated female epispadias, one-stage reconstruction of the urethra, bladder neck, labia minora and clitoris was performed...
March 2017: APSP Journal of Case Reports
https://www.readbyqxmd.com/read/28400394/urethrocutaneous-fistula-mimicking-vesicocutaneous-fistula-a-rare-entity
#11
Ruchir Aeron, Apul Goel, Ashok Kumar Sokhal, Sunny Goel
Urethral fistulas arising from the anterior urethra usually open on the ventral aspect and are located in the penile, scrotal or perineal region. A diabetic 65-year-old man presented with suprapubic urinary fistula that was communicating with a dorsally located internal urethral opening located in the bulbar region. Such unusual fistula has not been described before.
April 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28399523/sperm-sediment-cytology-a-new-technique-for-diagnosing-occult-urologic-infections
#12
Zhanna Sapozhkova, Karina Kasoyan, Elena Kovalchuk, Irina Shabalova
BACKGROUND: Ill-defined chronic symptoms such as itching, burning, urethral discharge, and pelvic pain are not uncommon in male urologic patients. Often, microscopic urinalysis, bacterial cultures, and laboratory testing are non-contributory. We have developed a technique for sperm sedimentation and used the cytologic examination of the sediment routinely in more than 4,000 patients with urologic complaints over the last 5 years. CASE: We present 3 exemplary cases, documenting the diagnostic power of sperm sediment cytology (SSC)...
April 12, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28394493/synergic-suppressive-effect-of-silodosin-and-imidafenacin-on-non-voiding-bladder-contractions-in-male-rats-with-subacute-bladder-outlet-obstruction
#13
Rino Sugiyama, Naoki Aizawa, Hiroki Ito, Tetsuya Fujimura, Motofumi Suzuki, Tohru Nakagawa, Hiroshi Fukuhara, Haruki Kume, Yukio Homma, Yasuhiko Igawa
OBJECTIVES: To investigate single or combined effect of silodosin, an α1A-adrenoceptor antagonist, and imidafenacin, an antimuscarinic agent, on bladder function in a subacute bladder outlet obstruction (BOO) model of male rats. METHODS: Partial BOO was created in male Wistar rats by ligating the urethra with a steel rod. On day 10 after surgery, when frequent voiding was most remarkable on voiding behavior measurement in a metabolic cage, cystometric investigations in a conscious restrained condition were conducted with cumulative intravenous administration of silodosin alone (0...
May 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28391989/towards-clinical-application-of-raystretch-for-heterogeneity-corrections-in-ldr-permanent-125-i-prostate-brachytherapy
#14
Fernando Hueso-González, Facundo Ballester, Jose Perez-Calatayud, Frank-André Siebert, Javier Vijande
PURPOSE: RayStretch is a simple algorithm proposed for heterogeneity corrections in low-dose-rate brachytherapy. It is built on top of TG-43 consensus data, and it has been validated with Monte Carlo (MC) simulations. In this study, we take a real clinical prostate implant with 71 (125)I seeds as reference and we apply RayStretch to analyze its performance in worst-case scenarios. METHODS AND MATERIALS: To do so, we design two cases where large calcifications are located in the prostate lobules...
April 5, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28386506/an-unusual-presentation-of-limited-granulomatosis-with-polyangiitis-involving-vagina-and-urethra
#15
Sandra Soro Marín, Enrique Júdez Navarro, Manuela Sianes Fernández, Ginés Sánchez Nievas, Juan Gabriel Lorenzo Romero
Granulomatosis with polyangiitis (GPA) is a systemic necrotizing granulomatosis vasculitis characterized by predilection to affect small- and medium-sized blood vessels and commonly affects the upper and lower respiratory tract and kidneys in most cases. Genital involvement is reported in <1% of cases in large cohorts and nearly all cases have been in the setting of multisystemic disease or during the course of the disease in patients already diagnosed as GPA. A case is presented of uncommon limited urogenital GPA in a 66-year-old woman with an irregular mass occupying urethra and vagina...
2017: Case Reports in Rheumatology
https://www.readbyqxmd.com/read/28385451/tissue-engineering-of-the-urethra-a-systematic-review-and-meta-analysis-of-preclinical-and-clinical-studies
#16
REVIEW
Luuk R M Versteegden, Paul K J D de Jonge, Joanna IntHout, Toin H van Kuppevelt, Egbert Oosterwijk, Wout F J Feitz, Rob B M de Vries, Willeke F Daamen
CONTEXT: Urethra repair by tissue engineering has been extensively studied in laboratory animals and patients, but is not routinely used in clinical practice. OBJECTIVE: To systematically investigate preclinical and clinical evidence of the efficacy of tissue engineering for urethra repair in order to stimulate translation of preclinical studies to the clinic. EVIDENCE ACQUISITION: A systematic search strategy was applied in PubMed and EMBASE...
April 3, 2017: European Urology
https://www.readbyqxmd.com/read/28385450/predictors-of-upper-tract-damage-in-pediatric-neurogenic-bladder
#17
Raghu Prakash, Archana Puri, Rama Anand, Ajay K Jain, Brahmanand Lal, Vaibhav Garg
INTRODUCTION: Upper tract damage (UTD) is a life-threatening complication of neurogenic bladder (NB). Early identification of risk factors for UTD and institution of remedial measures may probably prevent UTD. The aim was to study the predictors of UTD in children 2 years or older with NB. METHOD: This cross-sectional, observational study over 2 years included 30 children. UTD was defined as serum creatinine of >1 mg/dL or society of fetal urology grade III-IV hydronephrosis or hydroureteronephrosis on ultrasonography or renal scars on (99)(m)technetium dimercaptosuccinic scan or subnormal glomerular filtration rate (GFR) for age...
March 22, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28382576/in-vivo-human-corpus-cavernosum-regeneration-fabrication-of-tissue-engineered-corpus-cavernosum-in-rat-using-the-body-as-a-natural-bioreactor
#18
Abdol-Mohammad Kajbafzadeh, Reza Abbasioun, Nastaran Sabetkish, Shabnam Sabetkish, Ali Akbar Habibi, Kamyar Tavakkolitabassi
PURPOSE: Few researches have been conducted to develop an ideal method for tissue engineering of corpus cavernosum. We produce a decellularized human corpus cavernosum scaffold and investigate the in vivo cell seeding of the scaffold after transplantation into the rat omentum. METHODS: Eight adult human male corpus cavernosum were obtained in sterile condition. After dissecting the urethra, corpus cavernosum was decellularized by inserting an 18-gauge needle into the body of the tissue...
April 5, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28373959/penile-erosion-in-a-paraplegic-man-with-indwelling-urinary-catheter-and-scrotal-edema
#19
Ashley Young, Ryan Mitacek
The chronic use of urinary indwelling catheters is a common practice in the setting of long-term patient care and is associated with numerous complications. More awareness about urogenital trauma from urinary catheterization is needed, as it is as common as symptomatic urinary tract infections. There are a number of preventable measures that can be taken to decrease the risk of mechanical trauma to the urethra and glans penis caused by chronic catheterization. We present a case of a 27-year old paraplegic male needing a chronic indwelling catheter that acquired ventral penile erosion while being cared for in the ICU setting...
May 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28372274/stem-cell-roadmap%C3%A2-the-industrial-point-of%C3%A2-view
#20
Mazen Elzaabi, Agnès Thevenin, Pierre-Noël Lirsac
CELLforCURE is a French Contract Development and Manufacturing Organization (CDMO) dedicated to industrialization and process development for routine manufacturing, GMP manufacturing for clinical and commercial batches and regulatory services and associated logistics. CELLforCURE is a subsidiary of LFB Group.Stem cells fields of application gather cell and gene therapy as well as tissue engineering. According to VisionGain survey, cell therapy medicinal products will remain predominant in the future.Clinical trials are sponsored either by universities or private companies...
2017: Bio-medical Materials and Engineering
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