keyword
MENU ▼
Read by QxMD icon Read
search

bologña

keyword
https://www.readbyqxmd.com/read/29053653/patients-with-advanced-oral-squamous-cell-carcinoma-have-high-levels-of-soluble-e-cadherin-in-the-saliva
#1
S López-Verdín, J-J Soto-Avila, A-L Zamora-Perez, B-P Lazalde-Ramos, M-L Martínez-Fierro, R González-González, N Molina-Frechero, M-A Isiordia-Espinoza, R Bologna-Molina
BACKGROUND: The objective of this study was to assess the potential clinical value of the concentration of soluble salivary E-cadherin (sE-cadherin) compared with the clinical value of the presence of membranous E-cadherin (mE-cadherin) in oral squamous cell carcinoma tumor tissues. MATERIAL AND METHODS: Data regarding patient demographics, clinical stage, saliva and tumor tissue samples were collected. The saliva was analyzed for sE-cadherin protein levels and was compared to the mE-cadherin immunohistochemical expression levels in tumor tissues, which were assessed via the HercepTest® method...
October 20, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29051491/fan1-interaction-with-ubiquitylated-pcna-alleviates-replication-stress-and-preserves-genomic-integrity-independently-of-brca2
#2
Antonio Porro, Matteo Berti, Julia Pizzolato, Serena Bologna, Svenja Kaden, Anja Saxer, Yue Ma, Kazuo Nagasawa, Alessandro A Sartori, Josef Jiricny
Interstrand cross-link (ICL) hypersensitivity is a characteristic trait of Fanconi anemia (FA). Although FANCD2-associated nuclease 1 (FAN1) contributes to ICL repair, FAN1 mutations predispose to karyomegalic interstitial nephritis (KIN) and cancer rather than to FA. Thus, the biological role of FAN1 remains unclear. Because fork stalling in FAN1-deficient cells causes chromosomal instability, we reasoned that the key function of FAN1 might lie in the processing of halted replication forks. Here, we show that FAN1 contains a previously-uncharacterized PCNA interacting peptide (PIP) motif that, together with its ubiquitin-binding zinc finger (UBZ) domain, helps recruit FAN1 to ubiquitylated PCNA accumulated at stalled forks...
October 20, 2017: Nature Communications
https://www.readbyqxmd.com/read/29048454/are-the-school-prevention-programmes-aimed-at-de-normalizing-smoking-among-youths-beneficial-in-the-long-term-an-example-from-the-smoke-free-class-competition-in-italy
#3
V Zagà, F Giordano, P Gremigni, D L Amram, A De Blasi, M Amendola, J F Osborn, M S Cattaruzza
Tobacco smoking by young people is of great concern because it usually leads to regular smoking, nicotine addiction and quitting difficulties. Young people "hooked" by tobacco maintain the profits of the tobacco industry by replacing smokers who quit or die. If new generations could be tobacco-free, as supported by tobacco endgame strategies, the tobacco epidemic could end within decades. Smoking prevention programmes for teens are offered by schools with the aim to prevent or delay smoking onset. Among these, the Smoke Free Class Competition (SFC) was widely implemented in Europe...
November 2017: Annali di Igiene: Medicina Preventiva e di Comunità
https://www.readbyqxmd.com/read/29048453/bologna-process-and-basic-nursing-education-in-21-european-countries
#4
L Humar, J Sansoni
BACKGROUND: The Bologna Process and the Directives of the European Union have had a profound impact on nursing education in Europe. The aim of this study was to identify the similarities and differences within nursing education framework at entry level in 2014 in European countries. METHODS: A questionnaire was devised by the researchers and distributed via e-mail to the nursing associations/nursing regulatory bodies of 30 European countries. Data were collected from January to May 2014...
November 2017: Annali di Igiene: Medicina Preventiva e di Comunità
https://www.readbyqxmd.com/read/29040589/corifollitropin-alfa-followed-by-highly-purified-hmg-versus-recombinant-fsh-in-young-poor-ovarian-responders-a-multicentre-randomized-controlled-clinical-trial
#5
Panagiotis Drakopoulos, Thi Ngoc Lan Vuong, Ngoc Anh Vu Ho, Alberto Vaiarelli, Manh Tuong Ho, Christophe Blockeel, Michel Camus, Anh Tuan Lam, Arne van de Vijver, Peter Humaidan, Herman Tournaye, Nikolaos P Polyzos
STUDY QUESTION: Does administration of corifollitropin alfa followed by highly purified (hp) HMG result in higher ongoing pregnancy rates compared with daily recombinant FSH (rFSH) in young poor responders? SUMMARY ANSWER: Corifollitropin alfa followed by hp-HMG does not increase ongoing pregnancy rates compared with rFSH in young poor responders, although more supernumerary cryopreserved embryos were obtained with corifollitropin alfa and hp-HMG. WHAT IS KNOWN ALREADY: Poor ovarian response remains one of the main therapeutic challenges in women undergoing ovarian stimulation, given that very low live birth rates of 6% have been reported in this particular group of infertile patients...
September 23, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29035838/effect-of-two-treatment-protocols-for-ketosis-on-the-resolution-postpartum-health-milk-yield-and-reproductive-outcomes-of-dairy-cows
#6
Jae-Kwan Jeong, In-Soo Choi, Sung-Ho Moon, Soo-Chan Lee, Hyun-Gu Kang, Young-Hun Jung, Soo-Bong Park, Ill-Hwa Kim
We determined the effect of ketosis treatment with propylene glycol (PG) or PG plus l-carnitine and methionine (Metabolase(®), Fatro, Bologna, Italy) on the resolution, postpartum health, milk yield, and reproductive performances of dairy cows. Blood from 475 Holstein cows was collected weekly until 4 weeks after calving to measure blood β-hydroxybutyrate (BHBA) concentrations. Cows with blood BHBA concentration ≥1.2 mmol/L were diagnosed with ketosis and were enrolled. One hundred and fifty cows diagnosed with ketosis were randomly assigned to three treatment groups (Day 0): (1) PG (300 g, PO) for 3 days (PG group, n = 50), (2) PG (300 g, PO) plus l-carnitine (1...
September 25, 2017: Theriogenology
https://www.readbyqxmd.com/read/28993105/dual-trigger-of-final-oocyte-maturation-in-poor-ovarian-responders-undergoing-ivf-icsi-cycles
#7
Jie Zhang, Yun Wang, Xiaoyan Mao, Qiuju Chen, Qingqing Hong, Renfei Cai, Shaozhen Zhang, Yanping Kuang
Previous studies show that a dual trigger ovulation regimen significantly improves number and maturity of retrieved oocytes for normal ovarian responders or patients with history of low oocyte yield. The current retrospective cohort study investigated whether dual trigger of final oocyte maturation may benefit IVF outcomes for poor ovarian responders fulfilling the Bologna criteria. Undertaken between May 2014 and August 2016, the study involved 1350 patients undergoing 1389 IVF/intracytoplasmic sperm injection treatment cycles...
September 21, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28970447/the-country-profiles-of-the-pharmine-survey-of-european-higher-educational-institutions-delivering-pharmacy-education-and-training
#8
EDITORIAL
Jeffrey Atkinson
The PHARMINE (Pharmacy Education in Europe) consortium surveyed pharmacy education and practice in 2012. Surveys were updated in 2017 for publication. The PHARMINE consortium was especially interested in specialization in pharmacy education and practice (for community, hospital, and industrial pharmacy), and in the impact of the Bologna agreement and the directive of the European Commission on education and training for the sectoral profession of pharmacy on European degree courses. The surveys underline the varying attitudes of the different European countries to these various aspects...
June 22, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/28970429/competence-based-curricula-in-the-context-of-bologna-and-eu-higher-education-policy
#9
Howard Davies
At the turn of the century European higher education policy became twin-track. The Bologna Process was launched and ran alongside developments in European legislation. Both tracks displayed a preoccupation with competences, in relation both to citizenship and to labour market needs. Scrutiny of important policy texts (Key Competences, the European Qualifications Framework, ECTS, the Bologna three-cycle degree structure) shows that 'competence' has never been given a precise and secure definition. Only very recently has the term entered the discourse of EU legislation on the recognition of professional qualifications...
March 26, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/28969562/ovarian-stimulation-in-poor-responders-have-we-made-progress
#10
Robert Roman, Naiha Mussarat, Laura Detti
BACKGROUND: Poor ovarian responders (POR) pose a challenge to a physicians' ability to choose a stimulation protocol that maximizes the number of oocytes harvested and their chances of conception with multiple protocols aimed at improving pregnancy rates in this poor prognosis population. The Bologna criteria standardized the diagnosis of POR and allows for a more homogenous patient population in clinical trials. METHODS: A structured review of the literature, which encompasses research on Bologna-defined POR, identified several proposed protocols to optimize pregnancy rates in poor responders...
October 2, 2017: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/28968554/quality-evaluation-of-low-fat-bologna-type-meat-product-with-a-nutritional-profile-designed-for-the-elderly
#11
Elizabeth Reyes-Padilla, Martín Valenzuela-Melendres, Juan Pedro Camou, Joseph G Sebranek, Heliodoro Alemán-Mateo, José Luis Dávila-Ramírez, German Cumplido-Barbeitia, Humberto González-Ríos
The objective of this work was to evaluate the quality of a bologna-type meat product designed for the elderly. Treatments were: control, without addition of cranberries (C), prunes (P), pecan nuts (N) or flaxseed (F); NP, with 5% N+5% P; FC, with 5% F+5% C; NC, with 5% N+5% C; FP, with 5% F+5% P. These formulations resulted in a product with high protein, low SFA and high antioxidant activity. Treatments with pecan nuts had higher MUFA while those with flaxseed had higher polyunsaturated fatty acids (PUFA)...
September 20, 2017: Meat Science
https://www.readbyqxmd.com/read/28913136/clinical-analyses-of-successful-and-previously-failed-intracytoplasmic-sperm-injection-cycle-parameters-in-patients-with-poor-ovarian-reserve
#12
Tayfun Kutlu, Enis Özkaya, Pınar Kumru, Habibe Ayvacı, Belgin Devranoğlu, İlhan Sanverdi, Yavuz Şahin, Beyhan Sağlam, Ateş Karateke
OBJECTIVE: To determine some major characteristic differences between two consecutive successful and unsuccessful intracytoplasmic sperm injection (ICSI) cycles in poor responders. MATERIALS AND METHODS: Sixty women with poor ovarian response as determined using the Bologna criteria underwent ICSI cycles following an unsuccessful trial. Some parameters of both cycles including age, body mass index (BMI), serum follicle-stimulating hormone (FSH) and estradiol levels, antral follicle count, gonadotropin dosage, duration of stimulation, antagonist starting day, duration of antagonist administration, endometrial thickness at trigger day, number of total and fertilized oocytes, embryo transfer day, number of embryo cells, and fertilization rate were compared in the same patients to identify predictors of cycles with clinical pregnancy...
March 2017: Turk J Obstet Gynecol
https://www.readbyqxmd.com/read/28913129/evaluating-the-content-and-quality-of-intrapartum-care-in-vaginal-births-an-example-of-a-state-hospital
#13
Zekiye Karaçam, Döndü Arslan Kurnaz, Gizem Güneş
OBJECTIVE: The purpose of the research was to assess the content and quality of the intrapartum care offered in vaginal births in Turkey, based on the example of a state hospital. MATERIALS AND METHODS: This cross-sectional study was conducted between January 1(st), 2013 and December 31(st), 2014 at Aydın Maternity and Children's Hospital. The study sample consisted of 303 women giving vaginal birth, who were recruited into the study using the method of convenience sampling...
March 2017: Turk J Obstet Gynecol
https://www.readbyqxmd.com/read/28895678/prognosis-and-cost-effectiveness-of-ivf-in-poor-responders-according-to-the-bologna-criteria
#14
Andrea Busnelli, Edgardo Somigliana
Poor ovarian response (POR) to controlled ovarian hyperstimulation (COH) for in vitro fertilization (IVF) is one of the most challenging issue in the field of reproductive medicine. However, even if improving IVF outcome in poor responders (PORs) represents a main priority, the lack of a unique definition of POR has hampered research in this area. In order to overcome this impediment, an ESHRE Campus Workshop was organized in Bologna in 2010 and reached a consensus on the criteria for the diagnosis of POR ('Bologna criteria')...
September 12, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28890210/photodynamic-therapy-an-option-in-mycosis-fungoides
#15
Pileri Alessandro, Sgubbi Paola, Agostinelli Claudio, Infusino Salvatore Domenico, Vaccari Sabina, Patrizi Annalisa
BACKGROUND: Photodynamic therapy (PDT) is a well-known and effective treatment for non-melanoma skin-cancer. Numerous studies have also shown its effectiveness in mycosis fungoides. The aim of the study was to analyse MF patients treated with PDT at the Dermatology Unit of Bologna University. METHODS: We retrospectively analysed MF patients treated with PDT over the last ten years. Each PDT protocol consisted of the appliance for 3h under an occlusive film dressing on each lesion of a one-mm-thick layer of 16% methyl aminolaevulinate (MAL) 160mg/g cream (Metvix(®), Galderma, Paris, France)...
September 7, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28879829/five-year-surveillance-of-human-tuberculosis-caused-by-mycobacterium-bovis-in-bologna-italy-an-underestimated-problem
#16
G Lombardi, I Botti, M L Pacciarini, M B Boniotti, G Roncarati, P Dal Monte
Human tuberculosis (TB) caused by Mycobacterium bovis surveillance is affected by a lack of data. The aims of the present study were: (i) to estimate the proportion of human TB caused by M. bovis over a period of 5 years in Bologna, Northern Italy, which, like most Western European countries, has been declared bovine TB-free; (ii) to compare the genetic profiles of M. bovis strains identified in humans with those circulating in cattle in the last 15 years in Italy. Among 511 TB patients, the proportion of human TB caused by M...
October 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28875024/making-crystals-with-a-purpose-a-journey-in-crystal-engineering-at-the-university-of-bologna
#17
REVIEW
Dario Braga, Fabrizia Grepioni, Lucia Maini, Simone d'Agostino
The conceptual relationship between crystal reactivity, stability and meta-stability, solubility and morphology on the one hand and shape, charge distribution, chirality and distribution of functional groups over the molecular surfaces on the other hand is discussed, via a number of examples coming from three decades of research in the field of crystal engineering at the University of Bologna. The bottom-up preparation of mixed crystals, co-crystals and photoreactive materials starting from molecular building blocks across the borders of organic, organometallic and metalorganic chemistry is recounted...
July 1, 2017: IUCrJ
https://www.readbyqxmd.com/read/28873815/an-innovative-speech-based-user-interface-for-smarthomes-and-iot-solutions-to-help-people-with-speech-and-motor-disabilities
#18
Massimiliano Malavasi, Enrico Turri, Jose Joaquin Atria, Heidi Christensen, Ricard Marxer, Lorenzo Desideri, Andre Coy, Fabio Tamburini, Phil Green
A better use of the increasing functional capabilities of home automation systems and Internet of Things (IoT) devices to support the needs of users with disability, is the subject of a research project currently conducted by Area Ausili (Assistive Technology Area), a department of Polo Tecnologico Regionale Corte Roncati of the Local Health Trust of Bologna (Italy), in collaboration with AIAS Ausilioteca Assistive Technology (AT) Team. The main aim of the project is to develop experimental low cost systems for environmental control through simplified and accessible user interfaces...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28835940/pregnancy-outcome-of-delayed-start-gnrh-antagonist-protocol-versus-gnrh-antagonist-protocol-in-poor-responders-a-clinical-trial-study
#19
Abbas Aflatoonian, Aflatoonian Hosseinisadat, Ramesh Baradaran, Maryam Farid Mojtahedi
BACKGROUND: Management of poor-responding patients is still major challenge in assisted reproductive techniques (ART). Delayed-start GnRH antagonist protocol is recommended to these patients, but little is known in this regards. OBJECTIVE: The goal of this study was assessment of delayed-start GnRH antagonist protocol in poor responders, and in vitro fertilization (IVF) outcomes. MATERIALS AND METHODS: This randomized clinical trial included sixty infertile women with Bologna criteria for ovarian poor responders who were candidate for IVF...
April 2017: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/28825853/randomized-controlled-trial-testing-the-efficacy-of-platinum-free-interval-prolongation-in-advanced-ovarian-cancer-the-mito-8-mango-bgog-ov1-ago-ovar2-16-engot-ov1-gcig-study
#20
Sandro Pignata, Giovanni Scambia, Alessandra Bologna, Simona Signoriello, Ignace B Vergote, Uwe Wagner, Domenica Lorusso, Viviana Murgia, Roberto Sorio, Gabriella Ferrandina, Cosimo Sacco, Gennaro Cormio, Enrico Breda, Saverio Cinieri, Donato Natale, Giorgia Mangili, Carmela Pisano, Sabrina Chiara Cecere, Marilena Di Napoli, Vanda Salutari, Francesco Raspagliesi, Laura Arenare, Alice Bergamini, Jane Bryce, Gennaro Daniele, Maria Carmela Piccirillo, Ciro Gallo, Francesco Perrone
Purpose Platinum-based chemotherapy (PBC) for patients with progressing ovarian cancer (OC) is more effective with a longer time interval from previous platinum treatment (platinum-free interval [PFI]). In 1999, it was hypothesized that prolonging PFI with single-agent non-PBC (NPBC) may offer a strategy to improve overall outcome. MITO-8 aimed to verify this hypothesis commonly used in clinical practice although it has not been prospectively tested. Methods MITO-8 is an open-label, prospective, randomized, superiority trial...
October 10, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
keyword
keyword
72611
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"