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Chris Doe

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https://www.readbyqxmd.com/read/27920117/reliability-and-validity-of-the-dutch-version-of-the-consultation-and-relational-empathy-measure-in-primary-care
#1
Inge van Dijk, Nick Scholten Meilink Lenferink, Peter L B J Lucassen, Stewart W Mercer, Chris van Weel, Tim C Olde Hartman, Anne E M Speckens
BACKGROUND: Empathy is an essential skill in doctor-patient communication with positive effects on compliance, patient satisfaction and symptom duration. There are no validated patient-rated empathy measures available in Dutch. OBJECTIVE: To investigate the validity and reliability of a Dutch version of the Consultation and Relational Empathy (CARE) Measure, a widely used 10-item patient-rated questionnaire of physician empathy. METHODS: After translation and back translation, the Dutch CARE Measure was distributed among patients from 19 general practitioners in 5 primary care centers...
December 5, 2016: Family Practice
https://www.readbyqxmd.com/read/27908562/ontogeny-of-sensorimotor-gating-and-short-term-memory-processing-throughout-the-adolescent-period-in-rats
#2
Anja A Goepfrich, Chris M Friemel, Sabina Pauen, Miriam Schneider
Adolescence and puberty are highly susceptible developmental periods during which the neuronal organization and maturation of the brain is completed. The endocannabinoid (eCB) system, which is well known to modulate cognitive processing, undergoes profound and transient developmental changes during adolescence. With the present study we were aiming to examine the ontogeny of cognitive skills throughout adolescence in male rats and clarify the potential modulatory role of CB1 receptor signalling. Cognitive skills were assessed repeatedly every 10th day in rats throughout adolescence...
November 19, 2016: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/27906168/immunofluorescent-antibody-staining-of-intact-drosophila-larvae
#3
Laurina Manning, Chris Q Doe
Antibody staining is a vital technique for studying the development of many model organisms, including Drosophila. Reliable protocols have long been available for antibody staining of Drosophila whole-mount embryos and dissected larvae. By contrast, methods for staining whole larvae have rarely been reported, are unreliable, and fail to work on large third-instar larvae. This has become a major limitation to understanding the role of multitissue interactions such as neural circuit formation and cell metastasis...
January 2017: Nature Protocols
https://www.readbyqxmd.com/read/27904717/measurement-of-clavicle-fracture-shortening-using-computed-tomography-and-chest-radiography
#4
Reza Omid, Chris Kidd, Anthony Yi, Diego Villacis, Eric White
BACKGROUND: Nonoperative management of midshaft clavicle fractures has resulted in widely disparate outcomes and there is growing evidence that clavicle shortening poses the risk of unsatisfactory functional outcomes due to shoulder weakness and nonunion. Unfortunately, the literature does not clearly demonstrate the superiority of one particular method for measuring clavicle shortening. The purpose of this study was to compare the accuracy of clavicle shortening measurements based on plain radiographs with those based on computed tomography (CT) reconstructed images of the clavicle...
December 2016: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/27900317/does-early-career-achievement-lead-to-earlier-death-assessment-of-the-precocity-longevity-effect-in-professional-basketball-players
#5
Nick Wattie, Srdjan Lemez, Chris I Ardern, Michael Rotondi, Joseph Baker
OBJECTIVES: To examine the precocity-longevity (P-L) effect in North American professional basketball players who debuted between 1946 and 1979, and to determine whether playing position and decade of play influenced the relationship between age of career achievements and life span. METHODS: A total of 1852 players were evaluated from a recognized sports archive (i.e., http://sports-reference.com), which provided information on date of birth, death, and career debut, playing position, and indicators of achievement (i...
2016: Frontiers in Public Health
https://www.readbyqxmd.com/read/27893643/early-percutaneous-dilational-tracheostomy-does-not-lead-to-an-increased-risk-of-surgical-site-infection-following-anterior-spinal-surgery
#6
Chris Kaczmarek, Mirko Aach, Martin F Hoffmann, Emre Yilmaz, Christian Waydhas, Thomas A Schildhauer, Uwe Hamsen
BACKGROUND: Most patients suffering cervical spinal cord injuries require tracheostomy. The optimal timing is still a matter of debate. Previous studies showed that patients receiving early tracheostomy had fewer ventilator days, decreased rates of pneumonia, and were mobilized earlier. Due to the proximity of the anterior approach to the tracheostoma, there is concern about an increased risk of surgical site infection related to tracheostomy. METHODS: Retrospective analysis at a Level 1 trauma center of patient records from 2008-2014, identifying all patients with spinal cord injury who received anterior cervical spinal surgery and had early percutaneous dilational tracheostomy...
November 23, 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27883874/structured-interdisciplinary-bedside-rounds-do-not-reduce-length-of-hospital-stay-and-28-day-re-admission-rate-among-older-people-hospitalised-with-acute-illness-an-australian-study
#7
Elizabeth Huynh, David Basic, Rinaldo Gonzales, Chris Shanley
Objective Structured interdisciplinary bedside rounds (SIBR) are being implemented across many hospitals in Australia despite limited evidence of their effectiveness. This study evaluated the effect of SIBR on two interconnected outcomes, namely length of stay (LOS) and 28-day re-admission.Methods In the present before-after study of 3644 patients, twice-weekly SIBR were implemented on two aged care wards. Although weekly case conferences were shortened during SIBR, all other practices remained unchanged. Demographic, medical and frailty measures were considered in appropriate analyses...
November 25, 2016: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/27881718/variations-in-vibrissal-geometry-across-the-rat-mystacial-pad-base-diameter-medulla-and-taper
#8
Hayley Belli, Anne En-Tzu Yang, Chris Bresee, Mitra J Z Hartmann
Many rodents tactually sense the world through active motions of their vibrissae (whiskers), which are regularly arranged in rows and columns (arcs) on the face. The present study quantifies several geometric parameters of rat whiskers that determine the tactile information acquired. Findings include: 1) A meta-analysis of seven studies shows that whisker base diameter varies with arc length, with a surprisingly strong dependence on the whisker's row position within the array. 2) The length of the whisker medulla varies linearly with whisker length, and the medulla's base diameter varies linearly with whisker base diameter...
November 23, 2016: Journal of Neurophysiology
https://www.readbyqxmd.com/read/27876514/an-investigation-of-the-spatial-selectivity-of-the-duration-after-effect
#9
Jim Maarseveen, Hinze Hogendoorn, Frans A J Verstraten, Chris L E Paffen
Adaptation to the duration of a visual stimulus causes the perceived duration of a subsequently presented stimulus with a slightly different duration to be skewed away from the adapted duration. This pattern of repulsion following adaptation is similar to that observed for other visual properties, such as orientation, and is considered evidence for the involvement of duration-selective mechanisms in duration encoding. Here, we investigated whether the encoding of duration - by duration-selective mechanisms - occurs early on in the visual processing hierarchy...
November 19, 2016: Vision Research
https://www.readbyqxmd.com/read/27854224/can-human-pluripotent-stem-cell-derived-cardiomyocytes-advance-understanding-of-muscular-dystrophies
#10
Spandan Kalra, Federica Montanaro, Chris Denning
Muscular dystrophies (MDs) are clinically and molecularly a highly heterogeneous group of single-gene disorders that primarily affect striated muscles. Cardiac disease is present in several MDs where it is an important contributor to morbidity and mortality. Careful monitoring of cardiac issues is necessary but current management of cardiac involvement does not effectively protect from disease progression and cardiac failure. There is a critical need to gain new knowledge on the diverse molecular underpinnings of cardiac disease in MDs in order to guide cardiac treatment development and assist in reaching a clearer consensus on cardiac disease management in the clinic...
August 30, 2016: Journal of Neuromuscular Diseases
https://www.readbyqxmd.com/read/27849526/an-adaptive-array-excitation-scheme-for-the-unidirectional-enhancement-of-guided-waves
#11
Chris Adams, Sevan Harput, David Cowell, Thomas Carpenter, David Charutz, Steven Freear
Control over the direction of wave propagation allows an engineer to spatially locate defects. When imaging with longitudinal waves, time delays can be applied to each element of a phased array transducer to steer a beam. Because of the highly dispersive nature of guided waves, this beamsteering approach is sub-optimal. More appropriate time delays can be chosen to direct a guided wave if the dispersion relation of the material is known. Existing techniques however need a priori knowledge of material thickness and acoustic velocity, which changes as a function of temperature and strain...
November 11, 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/27846310/improving-mitochondrial-function-protects-bumblebees-from-neonicotinoid-pesticides
#12
Michael B Powner, Thomas E Salt, Chris Hogg, Glen Jeffery
Global pollination is threatened by declining insect pollinator populations that may be linked to neonicotinoid pesticide use. Neonicotinoids over stimulate neurons and depolarize their mitochondria, producing immobility and death. However, mitochondrial function can be improved by near infrared light absorbed by cytochrome c oxidase in mitochondrial respiration. In flies, daily exposure to 670nm light throughout life increases average lifespan and aged mobility, and reduces systemic inflammation. Here we treat bumble bees with Imidacloprid a common neonicotinoid...
2016: PloS One
https://www.readbyqxmd.com/read/27833242/socioecological-predictors-of-immune-defences-in-wild-spotted-hyenas
#13
Andrew S Flies, Linda S Mansfield, Emily J Flies, Chris K Grant, Kay E Holekamp
Social rank can profoundly affect many aspects of mammalian reproduction and stress physiology, but little is known about how immune function is affected by rank and other socio-ecological factors in free-living animals.In this study we examine the effects of sex, social rank, and reproductive status on immune function in long-lived carnivores that are routinely exposed to a plethora of pathogens, yet rarely show signs of disease.Here we show that two types of immune defenses, complement-mediated bacterial killing capacity (BKC) and total IgM, are positively correlated with social rank in wild hyenas, but that a third type, total IgG, does not vary with rank...
September 2016: Functional Ecology
https://www.readbyqxmd.com/read/27832643/cardiac-surgery-for-carcinoid-heart-disease-a-weapon-not-to-be-misused
#14
Maria Bonou, Chris J Kapelios, Gregory Kaltsas, Konstantinos Perreas, Konstantinos Toutouzas, John Barbetseas
Carcinoid heart disease (CHD) complicates approximately 25% of patients with a carcinoid tumor and carcinoid syndrome and leads to heart valve degeneration with mixed-stenotic and regurgitation pathology and consequent heart failure (HF) leading to significant morbidity and mortality. Cardiac surgery in symptomatic, severe CHD leads to significantly better functional capacity and prolonged survival when compared to medical treatment alone. Recent studies have shown improvement in postoperative outcomes of patients undergoing surgery for CHD over the last decades...
November 11, 2016: Cardiology
https://www.readbyqxmd.com/read/27826483/the-effect-of-timing-on-breast-reconstruction-outcomes-in-diabetic-women
#15
Melanie Major, Chris Devulapalli, Ricardo J Bello, Pablo A Baltodano, Myrna Eliann Reinhardt, Michele A Manahan, Carisa M Cooney, Gedge D Rosson
BACKGROUND: This study examines the effect of timing (immediate vs delayed) on postoperative morbidity in diabetic women undergoing breast reconstruction after mastectomy. METHODS: We reviewed the National Surgical Quality Improvement Program (NSQIP) databases from 2005 to 2012 for all diabetic women undergoing breast reconstruction. Multivariable logistic regression was used to estimate the risk of 30-day overall complications in the immediate versus delayed cohorts...
October 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27816801/medical-cannabis-and-mental-health-a-guided-systematic-review
#16
REVIEW
Zach Walsh, Raul Gonzalez, Kim Crosby, Michelle S Thiessen, Chris Carroll, Marcel O Bonn-Miller
This review considers the potential influences of the use of cannabis for therapeutic purposes (CTP) on areas of interest to mental health professionals, with foci on adult psychopathology and assessment. We identified 31 articles relating to the use of CTP and mental health, and 29 review articles on cannabis use and mental health that did not focus on use for therapeutic purposes. Results reflect the prominence of mental health conditions among the reasons for CTP use, and the relative dearth of high-quality evidence related to CTP in this context, thereby highlighting the need for further research into the harms and benefits of medical cannabis relative to other therapeutic options...
October 12, 2016: Clinical Psychology Review
https://www.readbyqxmd.com/read/27810026/does-osteoarthritis-of-the-ankle-joint-progress-after-triple-arthrodesis-a-midterm-prospective-outcome-study
#17
Chris A M Aarts, Petra J C Heesterbeek, Perry E M Jaspers, Mark Stegeman, Jan Willem K Louwerens
BACKGROUND: Debate exists regarding the effect of triple fusion on the development of osteoarthritis (OA) of the ankle joint. The midterm outcome after triple arthrodesis and the prevalence of OA following triple arthrodesis are reported in this study. The role of alignment in the development of OA was investigated. METHODS: Seventy five patients (87 feet) were evaluated in 2003 and of these, 48 patients (55 feet) were available for second evaluation in 2008. X-rays of the ankles and feet were made prior to surgery, in 2003 and in 2008, and the level of osteoarthritis (OA) was graded with the Kellgren and Lawrence score...
December 2016: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/27802150/feeding-through-your-gills-and-turning-a-toxicant-into-a-resource-how-the-dogfish-shark-scavenges-ammonia-from-its-environment
#18
Chris M Wood, Marina Giacomin
Nitrogen (N) appears to be a limiting dietary resource for elasmobranchs, required not only for protein growth but also for urea-based osmoregulation. Building on recent evidence that the toxicant ammonia can be taken up actively at the gills of the shark and made into the valuable osmolyte urea, we demonstrate that the uptake exhibits classic Michaelis-Menten saturation kinetics with an affinity constant (Km) of 379 µmol l(-1), resulting in net N retention at environmentally realistic ammonia concentrations (100-400 µmol l(-1)) and net N loss through stimulated urea-N excretion at higher levels...
October 15, 2016: Journal of Experimental Biology
https://www.readbyqxmd.com/read/27797351/radiology-case-of-the-month-persistent-lateral-foot-pain
#19
Chris Stark, Neel D Gupta, Michael Serou, Harold Neitzschman
A 33-year-old female presents with persistent lateral foot pain. Patient does not recall prior trauma that may have led to injury. Symptoms are significantly improved with rest and nonsteroidal anti-inflammatory medications.
September 2016: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/27794191/modulation-of-iron-transport-metabolism-and-reactive-oxygen-status-by-quercetin-iron-complexes-in-vitro
#20
Richard D Horniblow, Daisy Henesy, Tariq H Iqbal, Chris Tselepis
SCOPE: Excess free-iron is detrimental to health through its ability to participate in free radical generation and amplification of oncogenic pathways. The study aims were to identify polyphenols with iron-chelating potential. METHODS AND RESULTS: Of four polyphenols tested quercetin demonstrated potent iron binding with the physiological outcome dictated by the location of interaction. In the presence of extracellular iron and quercetin, ferritin expression and cellular iron concentrations decreased suggesting the resulting quercetin-iron complex is not internalised...
October 29, 2016: Molecular Nutrition & Food Research
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