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https://www.readbyqxmd.com/read/29151115/supramodal-effect-of-rightward-prismatic-adaptation-on-spatial-representations-within-the-ventral-attentional-system
#1
Isabel Tissieres, Eleonora Fornari, Stephanie Clarke, Sonia Crottaz-Herbette
Rightward prismatic adaptation (R-PA) was shown to alleviate not only visuo-spatial but also auditory symptoms in neglect. The neural mechanisms underlying the effect of R-PA have been previously investigated in visual tasks, demonstrating a shift of hemispheric dominance for visuo-spatial attention from the right to the left hemisphere both in normal subjects and in patients. We have investigated whether the same neural mechanisms underlie the supramodal effect of R-PA on auditory attention. Normal subjects underwent a brief session of R-PA, which was preceded and followed by an fMRI evaluation during which subjects detected targets within the left, central and right space in the auditory or visual modality...
November 18, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/29151024/insecticide-resistance-in-anopheles-arabiensis-from-ethiopia-2012-2016-a-nationwide-study-for-insecticide-resistance-monitoring
#2
Louisa A Messenger, Josephat Shililu, Seth R Irish, Gedeon Yohannes Anshebo, Alemayehu Getachew Tesfaye, Yemane Ye-Ebiyo, Sheleme Chibsa, Dereje Dengela, Gunawardena Dissanayake, Estifanos Kebede, Endalew Zemene, Abebe Asale, Mekonnen Yohannes, Hiwot Solomon Taffese, Kristen George, Christen Fornadel, Aklilu Seyoum, Robert A Wirtz, Delenasaw Yewhalaw
BACKGROUND: Indoor residual spraying (IRS) and long-lasting insecticidal nets (LLINs) remain the cornerstones of malaria vector control. However, the development of insecticide resistance and its implications for operational failure of preventative strategies are of concern. The aim of this study was to characterize insecticide resistance among Anopheles arabiensis populations in Ethiopia and describe temporal and spatial patterns of resistance between 2012 and 2016. METHODS: Between 2012 and 2016, resistance status of An...
November 18, 2017: Malaria Journal
https://www.readbyqxmd.com/read/29150614/spatial-regulation-of-contractility-by-neuralized-and-bearded-during-furrow-invagination-in-drosophila
#3
Gantas Perez-Mockus, Khalil Mazouni, Vanessa Roca, Giulia Corradi, Vito Conte, François Schweisguth
Embryo-scale morphogenesis arises from patterned mechanical forces. During Drosophila gastrulation, actomyosin contractility drives apical constriction in ventral cells, leading to furrow formation and mesoderm invagination. It remains unclear whether and how mechanical properties of the ectoderm influence this process. Here, we show that Neuralized (Neur), an E3 ubiquitin ligase active in the mesoderm, regulates collective apical constriction and furrow formation. Conversely, the Bearded (Brd) proteins antagonize maternal Neur and lower medial-apical contractility in the ectoderm: in Brd-mutant embryos, the ventral furrow invaginates properly but rapidly unfolds as medial MyoII levels increase in the ectoderm...
November 17, 2017: Nature Communications
https://www.readbyqxmd.com/read/29150504/temporal-stability-of-escherichia-coli-concentrations-in-waters-of-two-irrigation-ponds-in-maryland
#4
Yakov Pachepsky, Rachel Kierzewski, Matthew Stocker, Kevin Sellner, Walter Mulbry, Hoonsoo Lee, Moon Kim
Fecal contamination of water sources is an important water quality issue for agricultural irrigation ponds. Escherichia coli concentrations are commonly used to evaluate recreational and irrigation water quality. We hypothesized that there may exist temporally stable spatial patterns of E. coli concentrations across ponds meaning that some areas mostly have higher and other have mostly lower than average concentrations of E. coli To test this hypothesis, we sampled two irrigation ponds in Maryland in nodes of spatial grids biweekly during the summer of 2016...
November 17, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29150300/permanent-his-bundle-pacing-to-replace-biventricular-pacing-for-cardiac-resynchronization-therapy
#5
Benjamin J Scherlag, Alexa Papaila
INTRODUCTION: Cardiac resynchronization therapy (CRT) or biventricular pacing (BIVP) has become a common procedure for the treatment of ventricular dyssynchrony in patients with heart failure, particularly in those with bundle branch block patterns (QRS durations >150ms) on the electrocardiogram (ECG). However, a large group of non-responders are made up of patients with dyssynchrony and QRS duration below 130ms. Recent studies have introduced permanent His bundle pacing as another method for achieving normalization of the QRS duration even in a majority of patients with right or left bundle branch block pattern on the ECG...
November 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/29149875/prevalence-of-antibiotic-prescription-in-pediatric-outpatients-in-italy-the-role-of-local-health-districts-and-primary-care-physicians-in-determining-variation-a-multilevel-design-for-healthcare-decision-support
#6
Mirko Di Martino, Adele Lallo, Ursula Kirchmayer, Marina Davoli, Danilo Fusco
BACKGROUND: According to scientific literature, antibacterials are prescribed for common pediatric conditions that do not benefit from antibiotic therapy. The link between antibiotic use and bacterial resistance is well known. Antibiotic overprescribing generates high social costs and severe consequences for children. Our objectives were to analyze antibiotic prescription patterns in pediatric outpatients residing in the Lazio region (Italy), to identify physicians' characteristics associated with increased propensity for prescription, to identify the priority axes for action to improve the rational use of antibiotics...
November 17, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29149630/age-related-vulnerability-of-pattern-separation-in-c57bl-6j-mice
#7
Aurélia Cès, Thibaut Burg, Karine Herbeaux, Céline Héraud, Jean-Bastien Bott, Ayikoe Guy Mensah-Nyagan, Chantal Mathis
Aging is associated with impaired performance in behavioral pattern separation (PS) tasks based on similarities in object features and in object location. These deficits have been attributed to functional alterations in the dentate gyrus (DG)-CA3 region. Animal studies suggested a role of adult-born DG neurons in PS performance. The present study investigated the effect of aging in C57BL/6J mice performing PS tasks based on either object features or object location. At the age of 18 months or more, performance was severely impaired in both tasks...
October 25, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/29149617/decoding-early-and-late-cortical-contributions-to-individuation-of-attended-and-unattended-objects
#8
Claire K Naughtin, Jason B Mattingley, Angela D Bender, Paul E Dux
To isolate a visual stimulus as a unique object with a specific spatial location and time of occurrence, it is necessary to first register (individuate) the stimulus as a distinct perceptual entity. Recent investigations into the neural substrates of object individuation have suggested it is subserved by a distributed neural network, but previous manipulations of individuation load have introduced extraneous visual confounds, which might have yielded ambiguous findings, particularly in early cortical areas...
November 8, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29149506/integrating-soft-and-hard-tissues-via-interface-tissue-engineering
#9
REVIEW
Sahishnu Patel, Jon-Michael Caldwell, Stephen B Doty, William N Levine, Scott Rodeo, Louis J Soslowsky, Stavros Thomopoulos, Helen H Lu
The enthesis, or interface between bone and soft tissues such as ligament and tendon, is prone to injury and often does not heal post-surgical intervention. Interface tissue engineering represents an integrative strategy for regenerating the native enthesis by functionally connecting soft and hard tissues and thereby improving clinical outcome. This review focuses on integrative and cell-instructive scaffold designs that target the healing of the two most commonly injured soft tissue-bone junctions: the tendon-bone interface (e...
November 17, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29148964/twenty-five-years-of-the-binary-power-law-for-characterizing-heterogeneity-of-disease-incidence
#10
Laurence V Madden, Gareth Hughes, Wanderson Bucker Moraes, Xiangming Xu, William W Turechek
Spatial pattern, an important epidemiological property of plant diseases, can be quantified at different scales using a range of methods. The spatial heterogeneity (or overdispersion) of disease incidence among sampling units is an especially important measure of small-scale pattern. As an alternative to Taylor's power law for the heterogeneity of counts with no upper bound, the binary power law (BPL) was proposed in 1992 as a model to represent the heterogeneity of disease incidence (number of plant units diseased out of n observed in each sampling unit, or the proportion diseased in each sampling unit)...
November 17, 2017: Phytopathology
https://www.readbyqxmd.com/read/29148155/identifying-biomechanical-gait-parameters-in-adolescent-boys-with-haemophilia-using-principal-component-analysis
#11
L B Suckling, D Stephensen, M C Cramp, R Mahaffey, W I Drechsler
INTRODUCTION: Improvements in the medical management for those with haemophilia have resulted in improved clinical outcomes. However, current treatment regimens do not alleviate all joint haemarthroses with the potential for long-term joint deterioration remaining. The evaluation of functional activities such as gait, using standardized tools to monitor children with haemophilia is emerging. AIM: This study explored differences in sagittal plane biomechanics of walking in adolescent boys aged 11-18 years with haemophilia and an age-matched group of typically developing boys...
November 17, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/29148138/artificial-walking-technologies-to-improve-gait-in-cerebral-palsy-multichannel-neuromuscular-stimulation
#12
Jessica Rose, Katelyn Cahill-Rowley, Erin E Butler
Cerebral palsy (CP) is the most common childhood motor disability and often results in debilitating walking abnormalities, such as flexed-knee and stiff-knee gait. Current medical and surgical treatments are only partially effective in improving gait abnormalities and may cause significant muscle weakness. However, emerging artificial walking technologies, such as step-initiated, multichannel neuromuscular electrical stimulation (NMES), can substantially improve gait patterns and promote muscle strength in children with spastic CP...
November 2017: Artificial Organs
https://www.readbyqxmd.com/read/29148137/brain-computer-interfaces-with-multi-sensory-feedback-for-stroke-rehabilitation-a-case-study
#13
Danut C Irimia, Woosang Cho, Rupert Ortner, Brendan Z Allison, Bogdan E Ignat, Guenter Edlinger, Christoph Guger
Conventional therapies do not provide paralyzed patients with closed-loop sensorimotor integration for motor rehabilitation. This work presents the recoveriX system, a hardware and software platform that combines a motor imagery (MI)-based brain-computer interface (BCI), functional electrical stimulation (FES), and visual feedback technologies for a complete sensorimotor closed-loop therapy system for poststroke rehabilitation. The proposed system was tested on two chronic stroke patients in a clinical environment...
November 2017: Artificial Organs
https://www.readbyqxmd.com/read/29147740/geo-spatial-characterization-of-soil-mercury-and-arsenic-at-a-high-altitude-bolivian-gold-mine
#14
Glen D Johnson, Brian Pavilonis, Jack Caravanos, Jean Grassman
Soil mercury concentrations at a typical small-scale mine site in the Bolivian Andes were elevated (28-737 mg/kg or ppm) in localized areas where mercury amalgams were either formed or vaporized to release gold, but was not detectable beyond approximately 10 m from its sources. Arsenic was measurable, exceeding known background levels throughout the mine site (77-137,022 ppm), and was also measurable through the local village of Ingenio (36-1803 ppm). Although arsenic levels were high at all surveyed locations, its spatial pattern followed mercury, being highest where mercury was high...
November 16, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/29147578/modelling-historical-changes-in-the-force-of-infection-of-chagas-disease-to-inform-control-and-elimination-programmes-application-in-colombia
#15
Zulma M Cucunubá, Pierre Nouvellet, Lesong Conteh, Mauricio Javier Vera, Victor Manuel Angulo, Juan Carlos Dib, Gabriel Jaime Parra-Henao, María Gloria Basáñez
Background: WHO's 2020 milestones for Chagas disease include having all endemic Latin American countries certified with no intradomiciliary Trypanosoma cruzi transmission, and infected patients under care. Evaluating the variation in historical exposure to infection is crucial for assessing progress and for understanding the priorities to achieve these milestones. Methods: Focusing on Colombia, all the available age-structured serological surveys (undertaken between 1995 and 2014) were searched and compiled...
2017: BMJ Global Health
https://www.readbyqxmd.com/read/29147027/trapping-pinning-of-colloidal-microspheres-over-glass-substrate-using-surface-features
#16
Praneet Prakash, Manoj Varma
Suspensions of micro/nano particles made of Polystyrene, Poly(methyl methacrylate), Silicon dioxide etc. have been a standard model system to understand colloidal physics. These systems have proved useful insights into phenomena such as self-assembly. Colloidal model systems are also extensively used to simulate many condensed matter phenomena such as dynamics in a quenched disordered system and glass transition. A precise control of particles using optical or holographic tweezers is essential for such studies...
November 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29147005/binary-phase-masks-for-easy-system-alignment-and-basic-aberration-sensing-with-spatial-light-modulators-in-sted-microscopy
#17
André Klauss, Florian Conrad, Carsten Hille
The use of binary phase patterns to improve the integration and optimization of spatial light modulators (SLM) in an imaging system, especially a confocal microscope, is proposed and demonstrated. The phase masks were designed to create point spread functions (PSF), which exhibit specific sensitivity to major disturbances in the optical system. This allows direct evaluation of misalignment and fundamental aberration modes by simple visual inspection of the focal intensity distribution or by monitoring the central intensity of the PSF...
November 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29146909/interference-like-patterns-of-static-magnetic-fields-imprinted-into-polymer-nanoparticle-composites
#18
Zhijie Yang, Jingjing Wei, Konrad Giżynski, Myung-Geun Song, Bartosz A Grzybowski
Interference of waves is important and used in many areas of science and technology but does not extend to static magnetic fields which lack the wave structure. On the other hand, magnetic fields can be spatially modulated using microstructured materials comprising magnetic and non-magnetic domains. Here, we show that when such spatial modulation is coupled to the dynamics of magnetic particles, it can give rise to interference-like patterns. These patterns are imprinted into thin polymer films by overlaying "stamps" presenting periodic arrays of magnetic and nonmagnetic regions...
November 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/29146192/calcium-imaging-method-to-visualize-the-spatial-patterns-of-neural-responses-in-the-pygmy-squid-idiosepius-paradoxus-central-nervous-system
#19
Motoki Koizumi, Shuichi Shigeno, Makoto Mizunami, Nobuaki K Tanaka
BACKGROUND: Cephalopods exhibit unique behaviors such as camouflage and tactile learning. The brain functions correlated to these behaviors have long been analyzed through behavioral observations of animals subject to surgical manipulation or electrical stimulation of brain lobes. However, physiological methods have rarely been introduced to investigate the functions of each individual lobe, though physiological work on giant axons and slices of the vertical lobe system of the cephalopods have provided deep insights into ion conductance of nerves and long-term synaptic plasticity...
November 13, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29146075/persistent-organic-pollutant-emission-via-dust-deposition-throughout-pakistan-spatial-patterns-regional-cycling-and-their-implication-for-human-health-risks
#20
Muhammad Sohail, Syed Ali Musstjab Akber Shah Eqani, Joel Podgorski, Avit Kumar Bhowmik, Adeel Mahmood, Nadeem Ali, Tara Sabo-Attwood, Habib Bokhari, Heqing Shen
In the current study, Persistent Organic Pollutants (POPs) in outdoor dustfall was monitored for the first time along the Indus river system of Pakistan. Among the studied OCPs (ng/g, dry weight), DDTs (0.16-62) were the predominant contaminants identified in deposited dust followed by HCHs (0.1-10.2), HCB (0.09-7.4) and chlordanes (0.1-2.8). The indicative diagnostic ratio for DDTs and HCHs suggested recent emission of DDTs as well as historical emission of both chemicals in regions where they were used for crop protection and malarial control...
November 13, 2017: Science of the Total Environment
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