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https://www.readbyqxmd.com/read/28523987/six-month-effects-of-early-or-delayed-provision-of-an-ankle-foot-orthosis-in-patients-with-sub-acute-stroke-a-randomized-controlled-trial
#1
Corien Dm Nikamp, Jaap H Buurke, Job van der Palen, Hermie J Hermens, Johan S Rietman
OBJECTIVE: To study the six-month clinical effects of providing ankle-foot orthoses at different moments (early or delayed) in (sub)acute stroke; this is a follow-up to a published trial. DESIGN: Randomized controlled trial. SETTING: Rehabilitation centre. SUBJECTS: Unilateral hemiparetic stroke subjects maximal six weeks post-stroke with indication for ankle-foot orthosis use. INTERVENTIONS: Subjects were randomly assigned to early (at inclusion; week 1) or delayed provision (eight weeks later; week 9)...
May 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28514698/clinical-outcomes-and-frontal-plane-two-dimensional-biomechanics-during-the-30-second-single-leg-stance-test-in-patients-before-and-after-hip-abductor-tendon-reconstructive-surgery
#2
Rose E Huxtable, Timothy R Ackland, Gregory C Janes, Jay R Ebert
BACKGROUND: Hip abductor tendon tears are a common cause of Greater Trochanteric Pain Syndrome. Conservative treatments are often ineffective and surgical reconstruction may be recommended. This study investigated the improvement in clinical outcomes and frontal plane two-dimensional biomechanics during a 30-second single leg stance test, in patients undergoing reconstruction. We hypothesized that clinical scores and pertinent biomechanical variables would significantly improve post-surgery, and these outcomes would be significantly correlated...
May 10, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28514393/-subtraction-ct-angiopulmonographic-assessment-of-the-vascular-bed-and-lung-perfusion-in-patients-with-chronic-thromboembolic-pulmonary-hypertension-a-pilot-study
#3
T N Veselova, A Yu Demchenkova, T V Martynyuk, N M Danilov, S K Ternovoy, I E Chazova
AIM: To evaluate the vascular bed and lung perfusion in patients with chronic thromboembolic pulmonary hypertension (CTEPH) by computed tomography (CT) and to compare the severity of pulmonary arterial (PA) thrombotic lesions concurrent with parenchymal perfusion disorders with angiopulmonographic findings and clinical and hemodynamic characteristics. SUBJECTS AND METHODS: In the period from November 2015 to May 2016, 22 patients (7 men, 15 women) aged 27 to 67 years with a verified diagnosis of CTEPH were examined using an Aquilion ONE VISION Edition 640 (Toshiba Medical Systems, Japan) CT scanner with a 320-row detector...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28510680/effect-of-oral-iron-repletion-on-exercise-capacity-in-patients-with-heart-failure-with-reduced-ejection-fraction-and-iron-deficiency-the-ironout-hf-randomized-clinical-trial
#4
Gregory D Lewis, Rajeev Malhotra, Adrian F Hernandez, Steven E McNulty, Andrew Smith, G Michael Felker, W H Wilson Tang, Shane J LaRue, Margaret M Redfield, Marc J Semigran, Michael M Givertz, Peter Van Buren, David Whellan, Kevin J Anstrom, Monica R Shah, Patrice Desvigne-Nickens, Javed Butler, Eugene Braunwald
Importance: Iron deficiency is present in approximately 50% of patients with heart failure with reduced left ventricular ejection fraction (HFrEF) and is an independent predictor of reduced functional capacity and mortality. However, the efficacy of inexpensive readily available oral iron supplementation in heart failure is unknown. Objective: To test whether therapy with oral iron improves peak exercise capacity in patients with HFrEF and iron deficiency. Design, Setting, and Participants: Phase 2, double-blind, placebo-controlled randomized clinical trial of patients with HFrEF (<40%) and iron deficiency, defined as a serum ferritin level of 15 to 100 ng/mL or a serum ferritin level of 101 to 299 ng/mL with transferrin saturation of less than 20%...
May 16, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28510483/improvement-in-ventilation-perfusion-mismatch-after-bronchoscopic-lung-volume-reduction-quantitative-image-analysis
#5
Sei Won Lee, Sang Min Lee, So Youn Shin, Tai Sun Park, Sang Young Oh, Namkug Kim, Yoonki Hong, Jae Seung Lee, Yeon-Mok Oh, Sang-Do Lee, Joon Beom Seo
Purpose To evaluate whether bronchoscopic lung volume reduction (BLVR) increases ventilation and therefore improves ventilation-perfusion (V/Q) mismatch. Materials and Methods All patients provided written informed consent to be included in this study, which was approved by the Institutional Review Board (2013-0368) of Asan Medical Center. The physiologic changes that occurred after BLVR were measured by using xenon-enhanced ventilation and iodine-enhanced perfusion dual-energy computed tomography (CT). Patients with severe emphysema plus hyperinflation who did not respond to usual treatments were eligible...
May 16, 2017: Radiology
https://www.readbyqxmd.com/read/28509631/improving-balance-mobility-and-dual-task-performance-in-an-adolescent-with-cerebral-palsy-a-case-report
#6
Sarah Fisher-Pipher, Lisa K Kenyon, Marci Westman
BACKGROUND AND PURPOSE: Improving functional mobility is often a desired outcome for adolescents with cerebral palsy (CP). Traditional neurorehabilitation approaches are frequently directed at impairments; however, improvements may not be carried over into functional mobility. The purpose of this case report was to describe the examination, intervention, and outcomes of a task-oriented physical therapy intervention program to improve dynamic balance, functional mobility, and dual-task performance in an adolescent with CP...
May 16, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28505992/the-influence-of-a-constraint-and-bimanual-training-program-using-a-variety-of-modalities-on-endurance-and-on-the-cardiac-autonomic-regulation-system-of-children-with-unilateral-cerebral-palsy-a-self-control-clinical-trial
#7
Marilyn Cohen-Holzer, Gilad Sorek, Maayan Schweizer, Michal Katz-Leurer
BACKGROUND: An intensive hybrid program, combining constraint with bimanual training, improves upper extremity function as well as walking endurance of children with unilateral cerebral palsy (UCP). Endurance improvement may be associated with the cardiac autonomic regulation system (CARS) adaptation, known to be impaired among these children. OBJECTIVE: To examine the influence of an intensive hybrid program on CARS, walking endurance and the correlation with upper extremity function of children with UCP...
May 11, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28505988/intensive-seated-robotic-training-of-the-ankle-in-patients-with-chronic-stroke-differentially-improves-gait
#8
Johanna L Chang, Regina Y Lin, Maira Saul, Philip J Koch, Hermano Igo Krebs, Bruce T Volpe
BACKGROUND: Robotic driven treatment plans targeting isolated joints of the upper limb have improved the sensorimotor condition of patients with stroke. Similar intensive efforts to allay lower limb gait impairment have not been so successful. In patients with stroke, targeted robot assisted training of the ankle joint, in a seated position, has demonstrated significant alterations in ankle stiffness and foot-ankle orientation at foot strike which may provide a new treatment option for gait impairment...
May 10, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28503450/balance-assessment-in-subacute-stroke-patients-using-the-balance-control-trainer-balpro
#9
Jin Won Song, Jong Min Kim, Youn Soo Cheong, Yang-Soo Lee, Seong Min Chun, Yu-Sun Min, Tae-Du Jung
OBJECTIVE: To demonstrate the efficacy of the balance control trainer (BCT), developed for training patients with balance problems, as a balance assessment tool in subacute stroke patients. METHODS: A prospective cross-sectional study was carried out on 38 subacute stroke patients in their first episode of a stroke, and having the ability to maintain a standing position without aid for at least 5 minutes. Patients were assessed using the BCT (BalPro) 43.7±35.7 days after stroke...
April 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28503449/feasibility-of-rehabilitation-training-with-a-newly-developed-portable-gait-assistive-robot-for-balance-function-in-hemiplegic-patients
#10
Junhyun Sung, Sehoon Choi, Hyunbae Kim, Gyuhan Lee, Changsoo Han, Younghoon Ji, Dongbin Shin, Seunghoon Hwang, Deokwon Yun, Hyeyoun Jang, Mi Jung Kim
OBJECTIVE: To investigate the clinical feasibility of a newly developed, portable, gait assistive robot (WA-H, 'walking assist for hemiplegia') for improving the balance function of patients with stroke-induced hemiplegia. METHODS: Thirteen patients underwent 12 weeks of gait training on the treadmill while wearing WA-H for 30 minutes per day, 4 days a week. Patients' balance function was evaluated by the Berg Balance Scale (BBS), Fugl-Meyer Assessment Scale (FMAS), Timed Up and Go Test (TUGT), and Short Physical Performance Battery (SPPB) before and after 6 and 12 weeks of training...
April 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28490242/-telemetry-data-based-on-comparative-study-of-physical-activity-in-patients-with-resynchronization-device
#11
Csaba Melczer, László Melczer, Ilona Goják, Attila Kónyi, Sándor Szabados, L Bence Raposa, András Oláh, Pongrác Ács
INTRODUCTION: The effect of regular physical activity on health is widely recognized, but several studies have shown its key importance for heart patients. AIM: The present study aimed to define the PA % values, and to convert them into metabolic equivalent values (MET), which describes oxygen consumption during physical activity. METHOD: A total of seventeen patients with heart disease; 3 females and 14 males; age: 57.35 yrs ± 9.54; body mass 98...
May 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28488885/respiratory-muscle-strength-and-pulmonary-function-in-children-with-rhinitis-and-asthma-after-a-six-minute-walk-test
#12
Ana Alice de Almeida Soares, Camila Moraes Barros, Cássia Giulliane Costa Santos, Maria Renata Aragão Dos Santos, José Rodrigo Santos Silva, Walderi Monteiro da Silva Junior, Silvia de Magalhães Simões
OBJECTIVE: Rhinitis and asthma decrease quality of life. Few studies have assessed the performance of children with asthma or rhinitis under submaximal exercise. We evaluated maximal respiratory pressures, spirometric parameters, and ability to sustain submaximal exercise in these children before and after the 6-minute walk test (6MWT), compared to healthy children. METHODS: This cross-sectional, analytical study included 89 children aged 6-12 years in outpatient follow-up: 27 healthy (H), 31 with rhinitis (R), and 31 with mild asthma under control (A)...
May 10, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28488833/the-feasibility-of-an-exercise-program-for-individuals-12-months-post-stroke-in-a-small-urban-community
#13
David Jagroop, Amy Maebrae-Waller, Shilpa Dogra
BACKGROUND: There are few community-based exercise programs catering to individuals post-stroke, despite an increasing need. The primary objective of this study was to assess the feasibility of running a community-based exercise program for individuals post-stroke, and to provide a framework for local communities to run similar programs. METHODS: Individuals who had a stroke within 12 months of the start of the program were eligible to participate in a 9-week community-based exercise program...
May 9, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28487266/assessing-the-impact-of-a-novel-smartphone-application-compared-with-standard-follow-up-on-mobility-of-patients-with-knee-osteoarthritis-following-treatment-with-hylan-g-f-20-a-randomized-controlled-trial
#14
Nebojsa Skrepnik, Andrew Spitzer, Roy Altman, John Hoekstra, John Stewart, Richard Toselli
BACKGROUND: Osteoarthritis (OA) is a leading cause of disability in the United States. Although no disease-modifying therapies exist, patients with knee OA who increase walking may reduce risk of functional limitations. OBJECTIVE: The objective of the study is to evaluate the impact of a mobile app (OA GO) plus wearable activity monitor/pedometer (Jawbone UP 24) used for 90 days on the mobility of patients with knee OA treated with hylan G-F 20. METHODS: Patients with knee OA aged 30 to 80 years who were eligible to receive hylan G-F 20 and were familiar with smartphone technology were enrolled in this randomized, multicenter, open-label study...
May 9, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28486559/online-mindfulness-as-a-promising-method-to-improve-exercise-capacity-in-heart-disease-12-month-follow-up-of-a-randomized-controlled-trial
#15
Rinske A Gotink, John O Younge, Machteld F Wery, Elisabeth M W J Utens, Michelle Michels, Dimitris Rizopoulos, Liesbeth F C van Rossum, Jolien W Roos-Hesselink, Myriam M G Hunink
There is increasing evidence that mindfulness can reduce stress, and thereby affect other psychological and physiological outcomes as well. Earlier, we reported the direct 3-month results of an online modified mindfulness-based stress reduction training in patients with heart disease, and now we evaluate the effect at 12-month follow-up. 324 patients (mean age 43.2 years, 53.7% male) were randomized in a 2:1 ratio to additional 3-month online mindfulness training or to usual care alone. The primary outcome was exercise capacity measured with the 6 minute walk test (6MWT)...
2017: PloS One
https://www.readbyqxmd.com/read/28480853/-contemporary-approach-to-diagnosis-of-subclinical-heart-failure
#16
A Azaraksh, G Ivanov, N Bulanova, L Stazhadze, M Nikolaeva, V Vostrikov
Treatment of congestive heart failure (CHF) remains one of the challenging problems in cardiology. In recent years, the method of multifrequency bio-impendancemetry is used in patients with CHF for the assessment of water imbalance and determination of its severity. The aim of the study was to determine the diagnostic capabilities of bio-impendancemetry in evaluation of the early manifestations of CHF. The study included 92 healthy individuals, and 335 patients who were hospitalized in the cardiology department with NYHA I-II functional class (FC) of chronic CHF...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28480166/albuterol-as-an-adjunctive-treatment-to-enzyme-replacement-therapy-in-infantile-onset-pompe-disease
#17
Yin-Hsiu Chien, Wuh-Liang Hwu, Ni-Chung Lee, Fuu-Jen Tsai, Dwight D Koeberl, Wen-Hui Tsai, Pao-Chin Chiu, Chaw-Liang Chang
BACKGROUND: Early initiation of enzyme replacement therapy (ERT) with recombinant human acid alpha-glucosidase is an effective treatment for patients with infantile-onset Pompe disease (IOPD) but cannot prevent a slow progression of myopathy. Albuterol has been shown to be helpful in adult patients with Pompe disease, and therefore, we administered an open-label adjunctive therapy with albuterol in IOPD patients undergoing ERT. METHODS: Fourteen patients, aged 2 to 12 years, were enrolled in this study; all of them had a disease onset before 12 months of life, and 13 of them were ambulatory because of early initiation of ERT...
June 2017: Molecular Genetics and Metabolism Reports
https://www.readbyqxmd.com/read/28475703/cibinetide-improves-corneal-nerve-fiber-abundance-in-patients-with-sarcoidosis-associated-small-nerve-fiber-loss-and-neuropathic-pain
#18
Daniel A Culver, Albert Dahan, Daiva Bajorunas, Maria Jeziorska, Monique van Velzen, Leon P H J Aarts, Jinny Tavee, Martijn R Tannemaat, Ann N Dunne, Rita I Kirk, Ioannis N Petropoulos, Anthony Cerami, Rayaz A Malik, Michael Brines
Purpose: Sarcoidosis frequently is complicated by small nerve fiber loss (SNFL), which can be quantified using corneal confocal microscopy (CCM). Prior studies suggest that the innate repair receptor agonist cibinetide reverses corneal nerve loss. This phase 2b, 28-day, randomized trial of 64 subjects with sarcoid-associated SNFL and neuropathic pain assessed the effect of cibinetide on corneal nerve fiber area (CNFA) and regenerating intraepidermal fibers (GAP-43+) as surrogate endpoints for disease modification, pain severity, and functional capacity (6-minute walk test [6MWT])...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28475420/the-impact-of-previous-athletic-experience-on-current-physical-fitness-in-former-collegiate-athletes-and-noncollegiate-athletes
#19
Janet E Simon, Carrie L Docherty
BACKGROUND: Physical activity performed at moderate intensity is associated with reduced risk of mortality, cardiovascular disease, hypertension, and some types of cancers. However, vigorous physical activity during participation in college athletics may increase the risk of injury, which might limit future physical activity levels. PURPOSE: To evaluate differences in current physical fitness levels between former Division I athletes and noncollegiate athletes. STUDY DESIGN: Cross-sectional study...
May 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28468260/6mwt-performance-and-its-correlations-with-vo%C3%A2-and-handgrip-strength-in-home-dwelling-mid-aged-and-older-chinese
#20
Qing Zhang, Hailin Lu, Shiqin Pan, Yuan Lin, Kun Zhou, Li Wang
Six-minute walk test (6MWT) performance is more commonly used in clinic patients with chronic cardiopulmonary diseases but not in home-dwelling individuals of similar age, and its correlations with oxygen uptake (VO₂) and muscle strength require further investigation. The current study determined the 6MWT performance of 106 home-dwelling residents (mean age of 62 years) in Suzhou, China. VO₂ at a respiratory exchange ratio (R) of 1 was measured through graded cycling exercise tests on 46 participants. Handgrip strength of all participants was tested...
April 29, 2017: International Journal of Environmental Research and Public Health
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