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https://www.readbyqxmd.com/read/29164023/type-and-timing-of-rehabilitation-following-acute-and-subacute-spinal-cord-injury-a-systematic-review
#1
REVIEW
Anthony S Burns, Ralph J Marino, Sukhvinder Kalsi-Ryan, James W Middleton, Lindsay A Tetreault, Joseph R Dettori, Kathryn E Mihalovich, Michael G Fehlings
Objectives: The objective of this study was to conduct a systematic review of the literature to address the following clinical questions: In adult patients with acute and subacute complete or incomplete traumatic SCI, (1) does the time interval between injury and commencing rehabilitation affect outcome?; (2) what is the comparative effectiveness of different rehabilitation strategies, including different intensities and durations of treatment?; (3) are there patient or injury characteristics that affect the efficacy of rehabilitation?; and (4) what is the cost-effectiveness of various rehabilitation strategies? Methods: A systematic search was conducted for literature published through March 31, 2015 that evaluated rehabilitation strategies in adults with acute or subacute traumatic SCI at any level...
September 2017: Global Spine Journal
https://www.readbyqxmd.com/read/29160424/effect-of-prophylactic-non-invasive-mechanical-ventilation-on-functional-capacity-after-heart-valve-replacement-a-clinical-trial
#2
Amaro Afrânio de Araújo-Filho, Manoel Luiz de Cerqueira-Neto, Lucas de Assis Pereira Cacau, Géssica Uruga Oliveira, Telma Cristina Fontes Cerqueira, Valter Joviniano de Santana-Filho
OBJECTIVE: During cardiac surgery, several factors contribute to the development of postoperative pulmonary complications. Non-invasive ventilation is a promising therapeutic tool for improving the functionality of this type of patient. The aim of this study is to evaluate the functional capacity and length of stay of patients in a nosocomial intensive care unit who underwent prophylactic non-invasive ventilation after heart valve replacement. METHOD: The study was a controlled clinical trial, comprising 50 individuals of both sexes who were allocated by randomization into two groups with 25 patients in each group: the control group and experimental group...
October 2017: Clinics
https://www.readbyqxmd.com/read/29159458/cardiopulmonary-exercise-testing-reflects-improved-exercise-capacity-in-response-to-treatment-in-morquio-a-patients-results-of-a-52-week-pilot-study-of-two-different-doses-of-elosulfase-alfa
#3
Kenneth I Berger, Barbara K Burton, Gregory D Lewis, Mark Tarnopolsky, Paul R Harmatz, John J Mitchell, Nicole Muschol, Simon A Jones, V Reid Sutton, Gregory M Pastores, Heather Lau, Rebecca Sparkes, Adam J Shaywitz
OBJECTIVE: To assess impact of a 52-week elosulfase alfa enzyme replacement therapy (ERT) on exercise capacity in Morquio A patients and analyze cardiorespiratory and metabolic function during exercise to uncover exercise limitations beyond skeletal abnormalities. METHODS: Morquio A patients aged ≥7 years, able to walk >200 m in the 6-minute walk test (6MWT), received elosulfase alfa 2.0 mg/kg/week (N = 15) or 4.0 mg/kg/week (N = 10) for 52 weeks in the randomized, double-blind MOR-008 study ( ClinicalTrials...
November 21, 2017: JIMD Reports
https://www.readbyqxmd.com/read/29153637/quality-of-life-and-functional-capacity-outcomes-in-the-momentum-3-trial-at-6-months-a-call-for-new-metrics-for-left-ventricular-assist-device-patients
#4
Jennifer A Cowger, Yoshifumi Naka, Keith D Aaronson, Douglas Horstmanshof, Sanjeev Gulati, Debbie Rinde-Hoffman, Sean Pinney, Sirtaz Adatya, David J Farrar, Ulrich P Jorde
BACKGROUND: The Multicenter Study of MAGLEV Technology in Patients Undergoing Mechanical Circulatory Support Therapy with HeartMate 3 (MOMENTUM 3) clinical trial demonstrated improved 6-month event-free survival, but a detailed analysis of health-related quality of life (HR-QOL) and functional capacity (FC) was not presented. Further, the effect of early serious adverse events (SAEs) on these metrics and on the general ability to live well while supported with a left ventricular assist system (LVAS) warrants evaluation...
October 24, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29146543/cardiac-resynchronization-therapy-optimisation-of-interventricular-delay-by-the-systolic-dyssynchrony-index-a-comparative-randomized-12-month-follow-up-study
#5
Jiri Vondrak, Dan Marek, Jan Vecera, Klara Benesova, Jan Matejka
BACKGROUND: The aim of our study was to compare the effect of interventricular (VV) delay optimisation in CRT recipients based on systolic dyssynchrony index (SDI) derived from the three-dimensional echocardiography (3DE) versus QRS width assessment, on left ventricle volume reduction at the 12-month follow-up. METHODS: We included 63 patients with recently implanted CRT in this randomized, open-label trial. Patients were randomized to VV delay optimisation based on QRS complex width measurement in the group 1 (n=31) to obtain the narrowest QRS complex and based on SDI in group 2 (n=32) to achieve its lowest possible value...
November 13, 2017: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29144103/effects-of-home-based-superimposed-neuromuscular-electrical-stimulation-in-severe-chronic-obstructive-pulmonary-disease-patients-a-randomized-controlled-clinical-trial
#6
Marie C Valenza, Irene Torres-Sánchez, Laura López-López, Irene Cabrera-Martos, Araceli Ortiz-Rubio, Gerald Valenza-Demet
BACKGROUND: COPD patients experience a sustained deterioration of several capacities. Those with severe COPD undergo a considerable decline in their physical and functional capacities, but pulmonary rehabilitation (PR) is used to reduce the weakness of such patients. To date, neuromuscular electrical stimulation (NMES) has been used in acute COPD patients but NMES superimposed onto voluntary muscular contraction has not been tested in COPD patients. AIM: The aim of this study was to evaluate the effects of superimposed NMES on the cardiorespiratory performance and functionality of severe COPD patients undergoing a home-based rehabilitation program...
November 16, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29138552/sirt1-and-foxo1-mrna-expression-in-pbmc-correlates-to-physical-activity-in-copd-patients
#7
Chihiro Taka, Ryuji Hayashi, Kazuki Shimokawa, Kotaro Tokui, Seisuke Okazawa, Kenta Kambara, Minehiko Inomata, Toru Yamada, Shoko Matsui, Kazuyuki Tobe
Background: Physical activity (PA) is considered as one of the most important prognostic predictors in chronic obstructive pulmonary disease (COPD) patients. Longevity gene, SIRT1, is reported to be involved in the pathogenesis of COPD by regulating the signaling pathways of oxidative stress, inflammation, and aging. We hypothesize that SIRT1 and related genes are also associated with the benefits of PA in COPD patients. Methods: Eighteen COPD outpatients were enrolled in this study, and their PA level was assessed with an accelerometer...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29135399/-investigation-of-parameters-related-to-prognosis-in-diffuse-parenchymal-lung-diseases-prognosis-in-interstitial-lung-diseases
#8
Coşkun Canıvar, Züleyha Bingöl, Zeki Kılıçaslan, Tülin Çağatay, N Gülfer Okumuş
Introduction: Parameters related to prognosis in diffuse parenchymal lung disease (DPLD) have a decisive influence on treatment and follow-up processes. We aimed to define baseline characteristics and factors that effect the mortality of the group of patients with DPLD and to determine distinctions between subgroups. Materials and Methods: Demographic characteristics, complaints, comorbidity, treatment, pulmonary function tests, echocardiographic findings, six minute walking test (6MWT), arterial blood gases analysis, radiological findings and survival time were collected from outpatient clinics database...
September 2017: Tüberküloz Ve Toraks
https://www.readbyqxmd.com/read/29135398/the-effect-of-obesity-on-dyspnea-exercise-capacity-walk-work-and-workload-in-patients-with-copd
#9
Hülya Şahin, İlknur Naz, Yelda Varol, Berna Kömürcüoğlu
Introduction: COPD and obesity are major public health problems that cause mortality and morbidity all over the world. The combined of COPD and obesity is predicted to increase further in the coming years. Obesity primarily affects the pulmonary system by altering respiratory functions, exercise capacity, pulmonary gas exchange, and endurance and power of respiratory muscles. In this study, we aimed to compare the dyspnea sensation, exercise capacity, walk work and workload in obese COPD patients compared to preobese and normal overweight COPD patients...
September 2017: Tüberküloz Ve Toraks
https://www.readbyqxmd.com/read/29131689/do-pedometers-with-or-without-education-on-exercise-increase-functional-walking-capacity-and-physical-activity-level-in-adolescents-with-juvenile-idiopathic-arthritis
#10
Jill Blitz, Sara M Stern, Katherine Marzan
To evaluate the impact of pedometer use on the physical activity (PA) and functional walking capacity (FWC) of adolescents with juvenile idiopathic arthritis (JIA) and lower extremity (LE) involvement. Twenty-seven adolescents, aged 11-19 years with JIA and LE involvement, participated in the three-phase pedometer study that introduced the use of a pedometer and an education seminar at 6 weeks. Measurements were taken at the baseline first visit and at weeks 6, 12, and 20. The primary outcome measure was the 6-minute walk test (6MWT)...
November 13, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29131282/prognostic-value-of-daytime-heart-rate-blood-pressure-their-products-and-quotients-in-chronic-heart-failure
#11
Anna Kowalczys, Michał Bohdan, Marcin Gruchała
BACKGROUND: Chronic heart failure (CHF) is an important epidemiological and therapeuthic issue with poor prognosis. The aim of the study was to estimate the prognostic value of daytime heart rate (HR), blood pressure (BP), their products and quotients in patients with CHF. METHODS: The study included 80 stable patients with CHF and reduced left ventricular ejection fraction (LVEF ≤ 35%). Physical examination, laboratory blood tests, electrocardiogram, chest X-ray, echocardiography, 6-minute walk test (6MWT), telemetry monitoring and BP measurements were performed in all participants...
November 13, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/29127758/-physical-activity-the-holy-grail-of-modern-medicine
#12
Vladimír Tuka, Martina Daňková, Karel Riegel, Martin Matoulek
Movement is the basic attribute of life. It is not surprising that the return to regular physical activity is a very effective and cheap means of preventing and treating most non-cummunicable diseases. Therefore, every physician should be able to prescribe a suitable physical activity. The minimum amount of physical activity with proven effects in primary prevention of chronic diseases is relatively low: 150 minutes of moderate physical activity or 75 minutes of high intensity exercise per week or a combination of the two...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29125384/is-it-necessary-to-perform-prehabilitation-exercise-for-patients-undergoing-total-knee-arthroplasty-meta-analysis-of-randomized-controlled-trials
#13
Huifen Chen, Suyun Li, Tingyu Ruan, Li Liu, Li Fang
OBJECTIVES: This study was designed to test whether it is necessary to perform prehabilitation exercise for patients undergoing total knee arthroplasty (TKA). METHODS: Literatures were identified from Pubmed, Clinicaltrials, Cochrane library, and SpringerLink. All studies that compared a prehabilitation exercise group with control group before TKA were included. The primary outcome was length of hospital stay. Secondary outcomes were quadriceps strength and functional ability in short term (1...
November 10, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/29120969/clinical-and-physiological-effects-of-rollators-in-individuals-with-chronic-obstructive-pulmonary-disease-a-systematic-review
#14
Annemarie L Lee, Marla K Beauchamp, Roger S Goldstein, Dina Brooks
PURPOSE: To determine the effects of using a rollator in people with chronic obstructive pulmonary disease (COPD). METHODS: Studies were systematically identified from literature searches of MEDLINE, CINAHL, PEDro, PubMed, EMBASE, and the Cochrane Library databases and the reference lists of included studies. Two reviewers independently selected randomized controlled or crossover studies examining the effects of rollator usage compared with no aid in individuals with COPD...
November 8, 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/29117951/long-term-benefit-of-enzyme-replacement-therapy-in-pompe-disease-a-5-year-prospective-study
#15
Esther Kuperus, Michelle E Kruijshaar, Stephan C A Wens, Juna M de Vries, Marein M Favejee, Jan C van der Meijden, Dimitris Rizopoulos, Esther Brusse, Pieter A van Doorn, Ans T van der Ploeg, Nadine A M E van der Beek
OBJECTIVE: To determine the effect of enzyme replacement therapy (ERT) after 5 years and to identify predictors for a favorable response because few data are available on the long-term efficacy of ERT in Pompe disease. METHODS: We included 102 adult patients with Pompe disease in a nationwide, prospective cohort study. We assessed muscle strength (manual muscle testing with Medical Research Council [MRC] grading, handheld dynamometry [HHD]), muscle function (6-minute walk test, Quick Motor Function Test), daily life activities (Rasch-Built Pompe-Specific Activity [R-PAct] Scale), and pulmonary function (forced vital capacity [FVC] in upright and supine positions, maximum inspiratory and expiratory pressures) at 3- to 6-month intervals before and after the start of ERT...
November 8, 2017: Neurology
https://www.readbyqxmd.com/read/29111007/performed-and-perceived-walking-ability-in-relation-to-the-expanded-disability-status-scale-in-persons-with-multiple-sclerosis
#16
D Langeskov-Christensen, P Feys, I Baert, M Riemenschneider, E Stenager, U Dalgas
BACKGROUND: The severity of walking impairment in persons with multiple sclerosis (pwMS) at different levels on the expanded disability status scale (EDSS) is unclear. Furthermore, it is unclear if the EDSS is differently related to performed- and perceived walking capacity tests. AIMS: To quantify walking impairment and perceived impact of MS on walking according to EDSS scores and to examine the relations between these parameters in pwMS. METHODS: EDSS was collected by neurologists and walking was assessed by the timed 25ft walk test (T25FWT), two minute walk test (2MWT), six minute walk test (6MWT) and the 12-item MS walking scale (MSWS-12) in 474 PwMS with mild (EDSS 1-4: n=200) to moderate (EDSS 4...
November 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29107041/lateral-corticospinal-tract-damage-correlates-with-motor-output-in-incomplete-spinal-cord-injury
#17
Andrew C Smith, Kenneth A Weber, Denise R O'Dell, Todd B Parrish, Marie Wasielewski, James M Elliott
OBJECTIVE: To investigate the relationship between spinal cord damage and specific motor function in participants with incomplete spinal cord injury (iSCI). DESIGN: single-blinded cross-sectional study design SETTING: University setting research laboratory. PARTICIPANTS: Fourteen individuals with chronic cervical iSCI (1 female and 13 males, average age = 43 ± 12 years old). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Axial T2 MRI of spinal cord damage was performed in 14 participants with iSCI...
October 26, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29107040/longitudinal-recovery-and-reduced-costs-after-120-sessions-of-locomotor-training-for-motor-incomplete-spinal-cord-injury
#18
Sarah A Morrison, Douglas Lorenz, Carol P Eskay, Gail F Forrest, D Michele Basso
OBJECTIVE: To determine the impact of long term, body weight supported locomotor training (BWSLT) after chronic, incomplete spinal cord injury (SCI). Also, health care costs were estimated related to lost recovery potential and preventable secondary complications that may have occurred due to visit limits imposed by insurers. DESIGN: Prospective observational cohort with longitudinal follow up. SETTING: Eight outpatient rehabilitation centers that participate in the Christopher & Dana Reeve Foundation NeuroRecovery Network® (NRN)...
October 26, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29106679/toward-a-common-language-for-measuring-patient-mobility-in-the-hospital-reliability-and-construct-validity-of-interprofessional-mobility-measures
#19
Erik H Hoyer, Daniel L Young, Lisa M Klein, Julie Kreif, Kara Shumock, Stephanie Hiser, Michael Friedman, Annette Lavezza, Alan Jette, Kitty S Chan, Dale M Needham
Background: The lack of common language among interprofessional inpatient clinical teams is an important barrier to achieving inpatient mobilization. In The Johns Hopkins Hospital, the Activity Measure for Post-Acute Care (AM-PAC) Inpatient Mobility Short Form (IMSF), also called "6-Clicks,"and the Johns Hopkins Highest Level of Mobility (JH-HLM) are part of routine clinical practice. The measurement characteristics of these tools when used by both nurses and physical therapists for interprofessional communication or assessment are unknown...
November 2, 2017: Physical Therapy
https://www.readbyqxmd.com/read/29104679/physiotherapy-in-patients-with-chronic-obstructive-pulmonary-disease
#20
Antoaneta Dimitrova, Nikolay Izov, Ivan Maznev, Dance Vasileva, Milena Nikolova
BACKGROUND: Physiotherapy is an essential for the treatment of patients with chronic respiratory non-inflammatory diseases especially for chronic obstructive pulmonary disease (COPD). AIM: To assess the effect of six months physiotherapy (PT) program on functional status in patients with COPD. MATERIAL AND METHODS: The patients were divided into two groups according to the severity of the disease. Group A included 33 patients (mean age 68...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
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