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https://www.readbyqxmd.com/read/29773305/prediction-of-maximal-oxygen-uptake-by-six-minute-walk-test-and-body-mass-index-in-healthy-boys
#1
Majid Jalili, Farzad Nazem, Akbar Sazvar, Kamal Ranjbar
OBJECTIVE: To develop an equation to predict maximal oxygen uptake (VO2max) based on the 6-minute walk test (6MWT) and body composition in healthy boys. STUDY DESIGN: Direct VO2max, 6-minute walk distance, and anthropometric characteristics were measured in 349 healthy boys (12.49 ± 2.72 years). Multiple regression analysis was used to generate VO2max prediction equations. Cross-validation of the VO2max prediction equations was assessed with predicted residual sum of squares statistics...
May 14, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29769247/dementia-and-physical-activity-dapa-trial-of-moderate-to-high-intensity-exercise-training-for-people-with-dementia-randomised-controlled-trial
#2
Sarah E Lamb, Bart Sheehan, Nicky Atherton, Vivien Nichols, Helen Collins, Dipesh Mistry, Sukhdeep Dosanjh, Anne Marie Slowther, Iftekhar Khan, Stavros Petrou, Ranjit Lall
OBJECTIVE: To estimate the effect of a moderate to high intensity aerobic and strength exercise training programme on cognitive impairment and other outcomes in people with mild to moderate dementia. DESIGN: Multicentre, pragmatic, investigator masked, randomised controlled trial. SETTING: National Health Service primary care, community and memory services, dementia research registers, and voluntary sector providers in 15 English regions. PARTICIPANTS: 494 people with dementia: 329 were assigned to an aerobic and strength exercise programme and 165 were assigned to usual care...
May 16, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29765887/validation-of-korean-version-of-the-london-chest-activity-of-daily-living-scale-in-patients-with-chronic-obstructive-pulmonary-disease
#3
Jun Tak Choi, Jeong-Hwan Seo, Myoung-Hwan Ko, Sung-Hee Park, Gi-Wook Kim, Yu Hui Won
Objective: To translate the English version of the London Chest Activity of Daily Living scale (LCADL) into a Korean version and to determine the reliability and validity of the Korean version in patients with chronic obstructive pulmonary disease (COPD). Methods: The English version of LCADL was translated into Korean and back-translated into English. Subsequently, the back-translated version was reviewed and compared with the original, and thus the final K-LCADL was obtained...
April 2018: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29753346/clinical-outcome-assessments-use-of-normative-data-in-a-pediatric-rare-disease
#4
Dawn Phillips, Beth Leiro
Pediatric rare diseases present unique challenges in clinical trial design and in selection of clinical outcome assessments (COAs) used to support claims in medical product labeling. COAs that discriminate level of function relative to a normative sample are particularly important in the pediatric rare disease setting because the literature is often void of natural history data. Pediatric rare disease clinical trials will often include a wide age distribution. Gross and fine motor skills, communication, cognition, and independence in activities of daily living vary by age, and it may be difficult to distinguish between treatment effect and change due to developmental maturation...
May 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/29750973/effects-of-nutritional-prehabilitation-with-and-without-exercise-on-outcomes-of-patients-who-undergo-colorectal-surgery-a-systematic-review-and-meta-analysis
#5
Chelsia Gillis, Katherine Buhler, Lauren Bresee, Francesco Carli, Leah Gramlich, Nicole Culos-Reed, Tolulope T Sajobi, Tanis R Fenton
BACKGROUND & AIMS: Although there have been meta-analyses of the effects of exercise prehabilitation on patients undergoing colorectal surgery, little is known about the effects of nutrition-only (oral nutritional supplements and/or counseling) and multi-modal (oral nutritional supplements and/or counseling with exercise) prehabilitation on clinical outcomes and patient function after surgery. We performed a systemic review and meta-analysis to determine the individual and combined effects of nutrition-only and multi-modal prehabilitation, compared with no prehabilitation (control), on outcomes of patients undergoing colorectal resection...
May 8, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29750822/prediction-equation-to-estimate-heart-rate-at-individual-ventilatory-threshold-in-female-and-male-obese-adults
#6
Gian Pietro Emerenziani, Dafne Ferrari, Maria Grazia Vaccaro, Maria Chiara Gallotta, Silvia Migliaccio, Andrea Lenzi, Carlo Baldari, Laura Guidetti
OBJECTIVE: Prescribing individualized moderate exercise intensity is a useful method to reach positive effects on health status in obese adults. This study aimed to establish a practical reference equation to estimate the heart rate (HR) at individual ventilatory threshold (IVT) (HRIVT). METHODS: One hundred sixty-one obese subjects were clinically evaluated and characterized by anthropometric and body composition. Participants performed the six-minute walking test (6-MWT) and the cardiopulmonary exercise test to assess IVT...
2018: PloS One
https://www.readbyqxmd.com/read/29750030/validation-of-exhaled-volatile-organic-compounds-analysis-using-electronic-nose-as-index-of-copd-severity
#7
Panaiotis Finamore, Claudio Pedone, Simone Scarlata, Alessandra Di Paolo, Simone Grasso, Marco Santonico, Giorgio Pennazza, Raffaele Antonelli Incalzi
Aim: Six-minute walking test distance (6MWD) and body mass index, obstruction, dyspnea and exercise (BODE) index are measures of functional status in COPD patients, but require space, time and patient's compliance. Exhaled volatile organic compounds (VOCs) analysis via electronic nose is a quick and easy method that has already been used to discriminate COPD phenotypes. The aim of this study is to evaluate whether VOCs analysis can predict functional status and its variation over time in COPD patients...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29750023/the-effects-of-movement-stimulation-on-activities-of-daily-living-performance-and-quality-of-life-in-nursing-home-residents-with-dementia-a-randomized-controlled-trial
#8
Marinda Henskens, Ilse M Nauta, Katja T Drost, Erik Ja Scherder
Background: Nursing home (NH) residents with dementia experience a reduced quality of life (QoL), in part, due to a dependence in performing activities of daily living (ADL). Stimulating movement is associated with improvements in ADL performance. Therefore, movement stimulating interventions, such as ADL training and exercise, focus on optimizing ADL performance to improve QoL. This study aimed to evaluate the effect of three movement stimulating interventions on QoL and ADL performance in NH residents with dementia...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29747936/pulmonary-screening-in-subjects-after-the-fontan-procedure
#9
Deborah R Liptzin, Michael V Di Maria, Adel Younoszai, Michael R Narkewicz, Sarah L Kelly, Kelly R Wolfe, Livia A Veress
OBJECTIVES: To review the pulmonary findings of the first 51 patients who presented to our interdisciplinary single-ventricle clinic after undergoing the Fontan procedure. STUDY DESIGN: We performed an Institutional Review Board-approved retrospective review of 51 patients evaluated following the Fontan procedure. Evaluation included history, physical examination, pulmonary function testing, and 6-minute walk. Descriptive statistics were used to describe the population and testing data...
May 7, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29742798/longitudinal-timed-function-tests-in-duchenne-muscular-dystrophy-imagingdmd-cohort-natural-history
#10
Harneet Arora, Rebecca J Willcocks, Donovan J Lott, Ann T Harrington, Claudia R Senesac, Kirsten L Zilke, Michael J Daniels, Dandan Xu, Gihan I Tennekoon, Erika L Finanger, Barry S Russman, Richard S Finkel, William T Triplett, Barry J Byrne, Glenn A Walter, H Lee Sweeney, Krista Vandenborne
INTRODUCTION: Tests of ambulatory function are common clinical trial endpoints in Duchenne muscular dystrophy (DMD). The ImagingDMD study has generated a large data set using these tests, which can describe the contemporary natural history of DMD in 5-12.9 year olds. METHODS: 92 corticosteroid treated boys with DMD and 45 controls participated in this longitudinal study. Subjects performed the 6 minute walk test (6MWT) and timed function tests (TFTs: 10m walk/run, 4 stairs, supine to stand)...
May 9, 2018: Muscle & Nerve
https://www.readbyqxmd.com/read/29742145/effect-of-backpack-carrying-on-forced-vital-capacity-in-cystic-fibrosis-a-randomized-crossover-controlled-trial
#11
Yann Combret, Clement Medrinal, Guillaume Prieur, Aurora Robledo Quesada, Pascal Le Roux, Grégory Reychler
BACKGROUND: Backpack carrying impacts lung function in healthy children but the effect in children with cystic fibrosis (CF) is unknown. METHODS: Three backpack positions were tested: no backpack (NB), a 12.5% body-weight backpack carried bilaterally (BB) or unilaterally (UB), at rest and during a 10 minute walk. Primary outcome was forced vital capacity (FVC). Secondary outcomes included comparison of cardio-respiratory variables within and between groups. RESULTS: Nine children with CF (13...
2018: PloS One
https://www.readbyqxmd.com/read/29739254/curved-periacetabular-osteotomy-via-a-novel-intermuscular-approach-between-the-sartorius-and-iliac-muscles
#12
Toru Nishiwaki, Akihito Oya, Shinsuke Fukuda, Satoshi Nakamura, Masaya Nakamura, Morio Matsumoto, Arihiko Kanaji
INTRODUCTION: Herein, we describe and evaluate a curved periacetabular osteotomy (CPO) via an intermuscular approach (IM-CPO) between the sartorius and iliac muscles. METHODS: Between January 2009 and January 2016, IM-CPO was performed in 17 joints (16 patients), and a traditional CPO was performed in 17 joints. The length of incision at wound closure, operative time, intraoperative blood loss, serum creatinine kinase (CK) level the day after surgery, correctional angle, walking ability assessed using the gait items of the Harris Hip Score (at 3 and 6 months after surgery), and perioperative complications were evaluated...
May 1, 2018: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29737443/romberg-ratio-coefficient-in-quiet-stance-and-postural-control-in-parkinson-s-disease
#13
Teresa Paolucci, Marco Iosa, Giovanni Morone, Matteo Delle Fratte, Stefano Paolucci, Vincenzo M Saraceni, Ciro Villani
The aim of this study was to determine the function of visual afference in postural control in Parkinson patients. We enrolled 29 patients and 30 healthy controls. The stabilometry test was performed for posture and balance and Romberg ratio coefficients were calculated. In addition, the Berg Balance Scale and the 6-Minute Walking Test were administered to assess balance and functional exercise capacity; the Unified Parkinson's Disease Rating Scale was used to determine the stage of the disease; and the Short Form (SF)-36 Health Survey was given to collect information on quality of life...
May 8, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29731622/chronic-obstructive-pulmonary-disease-severity-and-its-association-with-obstructive-sleep-apnea-syndrome-impact-on-cardiac-autonomic-modulation-and-functional-capacity
#14
Katiany Thays Lopes Zangrando, Renata Trimer, Luiz Carlos Soares de Carvalho, Guilherme Peixoto Tinoco Arêas, Flávia Cristina Rossi Caruso, Ramona Cabiddu, Meliza Goi Roscani, Fabíola Paula Galhardo Rizzatti, Audrey Borghi-Silva
Background: The study was conducted to determine the impact of chronic obstructive pulmonary disease (COPD) in association with obstructive sleep apnea syndrome (OSAS) on cardiac autonomic control and functional capacity. Subjects and methods: The study was a cross-sectional prospective controlled clinical study. Heart rate variability indices of 24 COPD (n = 12) and COPD+OSAS (n = 12) patients were evaluated and compared by electrocardiographic recordings acquired during rest, active postural maneuver (APM), respiratory sinus arrhythmia maneuver (RSA-m), and the 6-minute walk test (6MWT)...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29730688/the-value-of-global-longitudinal-strain-and-galectin-3-for-predicting-cardiovascular-events-in-patients-with-severe-aortic-stenosis
#15
Lucia Agoston-Coldea, Kunal Bheecarry, Cristian Petra, Lelia Strambu, Camelia Ober, Radu Revnic, Silvia Lupu, Teodora Mocan, Daniela Fodor
AIMS: Left ventricular global longitudinal strain (GLS) was shown to predict outcomes after valve replacement in patients with aortic stenosis (AS). In the current study, we aimed to test the combined use of GLS and a marker of fibrosis - Galectin-3 - for predicting major cardiovascular adverse events (MACEs) in patients with severe AS. MATERIALS AND METHODS: We conducted a prospective study on 42 patients with severe AS and 42 volunteers. Patient evaluation included biochemistry tests, electrocardiogram, 24-hour Holter monitoring, the 6-minute walk test, and echocardiography...
May 2, 2018: Medical Ultrasonography
https://www.readbyqxmd.com/read/29727365/evaluating-muscle-mass-in-survivors-of-acute-respiratory-distress-syndrome-a-1-year-multicenter-longitudinal-study
#16
Kitty S Chan, Marina Mourtzakis, Lisa Aronson Friedman, Victor D Dinglas, Catherine L Hough, E Wesley Ely, Peter E Morris, Ramona O Hopkins, Dale M Needham
OBJECTIVES: Rapid muscle wasting occurs during acute respiratory failure, resulting in muscle weakness and functional impairments. This study examines survivors' body composition in the year after acute respiratory distress syndrome and tests associations of patient characteristics, hospital exposures, and survivors' strength and physical functioning with whole body percent lean mass. DESIGN: Prospective cohort study with 6- and 12-month follow-up. SETTING: National study enrolling patients from five study centers...
May 4, 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29724398/determinants-of-functional-peak-and-endurance-exercise-capacity-in-people-with-chronic-obstructive-pulmonary-disease
#17
Renae J McNamara, Sarah Houben-Wilke, Frits M E Franssen, Dionne E Smid, Lowie E G W Vanfleteren, Miriam T J Groenen, Nicole H M K Uszko-Lencer, Emiel F M Wouters, Jennifer A Alison, Martijn A Spruit
BACKGROUND: Exercise limitation in COPD is multi-factorial. The contribution of cardiac function to exercise capacity is not clear. METHODS: Potential determinants of the different constructs of exercise capacity (functional, peak and endurance exercise capacity using the 6-minute walk distance (6MWD), peak oxygen uptake (VO2 peak) and peak work load, and sub-maximal constant work rate test (CWRT) cycle time, respectively) were analysed. RESULTS: Data were collected in 516 people with COPD (56% male, age (mean ± SD) 64 ± 9 years, FEV1 % predicted 49 ± 20%)...
May 2018: Respiratory Medicine
https://www.readbyqxmd.com/read/29722619/whole-body-vibration-training-increases-physical-measures-and-quality-of-life-without-altering-inflammatory-oxidative-biomarkers-in-patients-with-moderate-copd
#18
Camila Danielle Cunha Neves, Ana Cristina Rodrigues Lacerda, Vanessa Kelly Silva Lage, Aline Alves Soares, Maria Gabriela Abreu Chaves, Liliana Pereira Lima, Thyago José Silva, Érica Leandro Marciano Vieira, Antônio Lúcio Teixeira, Hércules Ribeiro Leite, Mariana Aguiar Matos, Vanessa Amaral Mendonça
The whole-body vibration training (WBVT) has been identified as an alternative intervention to improve exercise capacity and quality of life of patients with Chronic Obstructive Pulmonary Disease (COPD). However, the effect of WBVT on inflammatory-oxidative biomarkers remains unknown. The aim of this trial was to investigate the effects of WBVT on quality of life and physical and inflammatory-oxidative parameters in patients with COPD. Twenty patients were equally divided into: 1) intervention group (IG) that performed the WBVT, and 2) control group (CG) that did not receive any intervention...
May 3, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29715295/mobility-limitations-related-to-reduced-pulmonary-function-among-aging-people-with-chronic-obstructive-pulmonary-disease
#19
Francesc Medina-Mirapeix, Roberto Bernabeu-Mora, Mª Piedad Sánchez-Martínez, Joaquina Montilla-Herrador, Myriam Bernabeu-Mora, Pilar Escolar-Reina
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a major cause of disability. We aimed to analyse the impact of reduced pulmonary function on non-respiratory impairments and mobility activity limitations in an elderly population with COPD and to elucidate which specific limitations on mobility are related to reduced pulmonary function. METHODS: Cross-sectional study of 110 patients with COPD, recruited from public and university hospital. The effect of impaired pulmonary function on the risk of non-respiratory impairments and mobility limitations was analysed using validated measures, including: the 6-Minute Walk Test (6MWT), skeletal muscle strength, the Short Physical Performance Battery (SPPB), and self-reported mobility questionnaire...
2018: PloS One
https://www.readbyqxmd.com/read/29713153/long-term-effects-of-oxygen-enriched-high-flow-nasal-cannula-treatment-in-copd-patients-with-chronic-hypoxemic-respiratory-failure
#20
Line Hust Storgaard, Hans-Ulrich Hockey, Birgitte Schantz Laursen, Ulla Møller Weinreich
Background: This study investigated the long-term effects of humidified high-flow nasal cannula (HFNC) in COPD patients with chronic hypoxemic respiratory failure treated with long-term oxygen therapy (LTOT). Patients and methods: A total of 200 patients were randomized into usual care ± HFNC. At inclusion, acute exacerbation of COPD (AECOPD) and hospital admissions 1 year before inclusion, modified Medical Research Council (mMRC) score, St George's Respiratory Questionnaire (SGRQ), forced expiratory volume in 1 second (FEV1 ), 6-minute walk test (6MWT) and arterial carbon dioxide (PaCO2 ) were recorded...
2018: International Journal of Chronic Obstructive Pulmonary Disease
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