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Grace S Li
No abstract text is available yet for this article.
September 2016: Journal of Thoracic Disease
Rene Razzak, Todd McMullen, Eric L R Bédard
We report a case involving a female patient with primary hyperparathyroidism arising from a middle mediastinal parathyroid adenoma. Initial diagnosis was made based on a history of polyuria and recurrent renal colic. At the age of 77 she underwent videoscopic assisted mediastinoscopy (VAM) for resection of the adenoma which was localized using single-photon emission computed tomography (SPECT/CT). This case illustrates the importance for accurate pre-operative localization and intra-operative monitoring to ensure complete surgical removal in order to improve postoperative normocalcemia success rates...
September 2016: Journal of Thoracic Disease
Bode Falase, Mgbajah Ogadinma, Adetinuwe Majekodunmi, Barakat Nimasahun, Olufunke Adeyeye
INTRODUCTION: Cervical mediastinoscopy is the gold standard for obtaining histological diagnosis of mediastinal pathology. It has been used for the staging of lung cancer as well as to determine the cause of Isolated Mediastinal Lymphadenopathy. There is very limited evidence in the literature of its use in Nigeria to assess mediastinal pathology. The aim of this study was to describe our institutional experience with cervical mediastinoscopy. METHODS: This study was a retrospective analysis of 40 patients that underwent cervical mediastinoscopy in our institution between March 2007 and February 2013...
2016: Pan African Medical Journal
Inderpaul Singh Sehgal, Sahajal Dhooria, Ashutosh Nath Aggarwal, Digambar Behera, Ritesh Agarwal
Whether endosonography can replace mediastinoscopy as the initial procedure for mediastinal staging of non-small cell lung cancer remains controversial. Herein, we perform a systematic review of randomized controlled trials and observational studies (both procedures performed in same subjects) comparing the two procedures. Nine studies (960 subjects) were identified. The pooled risk-difference of the sensitivity of endosonography versus mediastinoscopy in observational studies and randomized controlled trials was 0...
September 13, 2016: Annals of Thoracic Surgery
Jolanda C Kuijvenhoven, Daniël A Korevaar, Kurt G Tournoy, Thomas L A Malfait, Christophe Dooms, Robert C Rintoul, Jouke T Annema
No abstract text is available yet for this article.
September 13, 2016: JAMA: the Journal of the American Medical Association
Mohamed K Kamel, Mohamed Rahouma, Galal Ghaly, Abu Nasar, Jeffrey L Port, Brendon M Stiles, Andrew B Nguyen, Nasser K Altorki, Paul C Lee
BACKGROUND: Patients with persistent N2 disease after induction have poor survival. Many of these patients may have had mediastinoscopy before induction therapy, making reassessment of the mediastinum by repeat mediastinoscopy hazardous and inaccurate. The sensitivity and specificity of endobronchial ultrasonography and nodal fine-needle aspiration in this setting is unclear. In this study, we sought to identify the clinical predictors of persistent N2 disease after induction therapy, which may help in selecting the patients most likely to benefit from surgical resection...
September 9, 2016: Annals of Thoracic Surgery
Jessica Glover, Frank O Velez-Cubian, Kavian Toosi, Emily Ng, Carla C Moodie, Joseph R Garrett, Jacques P Fontaine, Eric M Toloza
BACKGROUND: Induction therapy has been shown to benefit patients with resectable stage-2 or stage-3 non-small cell lung cancer (NSCLC). We aimed to determine if induction chemotherapy (CTx) with or without radiation therapy (± RT) for NSCLC with clinical lymph node (LN) involvement (cN1 or cN2) affects LN dissection or perioperative outcomes during robotic-assisted video thoracoscopic (RAVTS) lobectomy. METHODS: We retrospectively analyzed patients who underwent RAVTS lobectomy for NSCLC over 45 months...
August 2016: Journal of Thoracic Disease
Youn Ju Rhee, Sung Joon Han, Yoo Young Chong, Hyun Jin Cho, Shin Kwang Kang, Choong-Sik Lee, Min-Woong Kang
Paratracheal air cysts are a rare entity in which cystic formation occurs adjacent to the trachea. Most patients with paratracheal air cysts are asymptomatic, and the cysts are detected incidentally on chest radiograph or computed tomography (CT) scan. Most symptomatic patients complain of pulmonary symptoms or repeated respiratory infection. Rarely, the air cysts can lead to paralysis of the recurrent laryngeal nerve as a result of direct compression. We report a case of a 59-year-old male patient who presented with voice change, and the cause was identified as paratracheal air cysts on a chest CT scan...
August 2016: Korean Journal of Thoracic and Cardiovascular Surgery
Tomasz Gil, Janusz Warmus, Janusz Włodarczyk, Zbigniew Grochowski, Krzysztof Bederski, Piotr Kocoń, Piotr Talar, Jarosław Kużdżał
INTRODUCTION: Iatrogenic tracheobronchial injuries are rare. AIM: To analyse the mechanism of injury, symptoms and treatment of these patients. MATERIAL AND METHODS: Retrospective analysis of hospital records of all patients treated for main airway injuries between 1990 and 2012 was performed. RESULTS: There were 24 patients, including 21 women and 3 men. Mean time between injury and initiation of treatment was 12 hours (range: 2-48)...
June 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
Felix D Zamora, Anas Moughrabieh, Heidi Gibson, Eitan Podgaetz, H Erhan Dincer
Endobronchial ultrasound-guided transbronchial needle aspiration has a low complication rate and is a cost-effective procedure for mediastinal staging and diagnosis when compared with the more invasive mediastinoscopy. There are increasing case reports of unexpected complications including equipment failures with and without significant medical consequences. Knowledge of complications, including those that are rare, is essential for the physician performing this minimally invasive procedure. We report a case of a retained foreign body from the unexpected separation of a distal spring/coil mechanism from the Olympus ViziShot Aspiration needle following early needle deployment within the working channel of the bronchoscope...
July 29, 2016: Journal of Bronchology & Interventional Pulmonology
Duc Ha, Xiaoyan Liao, Huan-You Wang, Catriona Jamieson, Marisa Magaña, Samir Makani
Thoracic extramedullary hematopoiesis (EMH) is a rare manifestation in patients with myeloproliferative neoplasm. A 76-year-old woman with a long-standing history of polycythemia vera presented with a 2-month history of worsening dyspnea and left-sided wheezing. A chest computed tomography showed an ill-defined soft tissue mass encasing the left mainstem bronchus causing airway obstruction, associated with paratracheal and paraesophageal lymphadenopathy. Endobronchial ultrasound-guided fine needle aspiration of the soft tissue mass and mediastinoscopy with excisional biopsy of a paratracheal lymph node demonstrated EMH with increased myeloid blasts...
July 29, 2016: Journal of Bronchology & Interventional Pulmonology
Kaoru Kaseda, Keisuke Asakura, Akio Kazama, Yukihiko Ozawa
BACKGROUND: Lymph nodes in patients with non-small cell lung cancer (NSCLC) are often staged using integrated 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT). However, this modality has limited ability to detect micrometastases. We aimed to define risk factors for occult lymph node metastasis in patients with clinical stage I NSCLC diagnosed by preoperative integrated FDG-PET/CT. METHODS: We retrospectively reviewed the records of 246 patients diagnosed with clinical stage I NSCLC based on integrated FDG-PET/CT between April 2007 and May 2015...
July 25, 2016: World Journal of Surgery
Pravachan V C Hegde, Moishe Liberman
Combined endosonographic lymph node biopsy techniques are a minimally invasive alternative to surgical staging in non-small cell lung cancer and may be superior to standard mediastinoscopy and surgical mediastinal staging techniques. Endosonography allows for the biopsy of lymph nodes and metastases unattainable with standard mediastinoscopy. Standard cervical mediastinoscopy is an invasive procedure, which requires general anesthesia and is associated with higher risk, cost, and major complication rates compared with minimally invasive endosonographic biopsy techniques...
August 2016: Thoracic Surgery Clinics
Whittney A Warren, Jared T Hagaman
RATIONALE: Endobronchial ultrasound guided transbronchial needle aspiration and positron emission tomography-computed tomography are valuable tools for lung cancer staging. Data from tertiary referral centers suggest these modalities are superior to mediastinoscopy in mediastinal staging. OBJECTIVE: Validate endobronchial ultrasound guided transbronchial needle aspiration for lung cancer staging in a community center with operators of varying experience. METHODS: At an 800-bed community hospital, we reviewed all cases where endobronchial ultrasound-guided transbronchial needle aspiration and positron emission tomography-computed tomography were performed for mediastinal staging by one of seven private practice pulmonologists...
July 13, 2016: Annals of the American Thoracic Society
Dariusz Dziedzic, Adam Peryt, Malgorzata Szolkowska, Renata Langfort, Tadeusz Orlowski
BACKGROUND AND OBJECTIVES: The mediastinum is a relatively uncommon site of distant metastases, which typically appear as peripheral lung nodules. We chose to assess the utility of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for the diagnosis of distant metastases to the mediastinum. MATERIALS AND METHODS: Over the period 2008-2013, a total of 446 patients with concurrent or previously diagnosed and treated extrathoracic malignancies were evaluated...
May 2016: Endoscopic Ultrasound
Kaoru Kaseda, Ken-Ichi Watanabe, Keisuke Asakura, Akio Kazama, Yukihiko Ozawa
BACKGROUND: The aim of this study was to evaluate the diagnostic accuracy of integrated (18) F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in hilar and mediastinal lymph node (HMLN) staging of non-small cell lung cancer (NSCLC), and to investigate potential risk factors for false-negative and false-positive HMLN metastases. METHODS: We examined the data of 388 surgically resected NSCLC patients preoperatively staged by integrated FDG-PET/CT...
July 2016: Thoracic Cancer
Adnan Sayar, Necati Çitak, Songül Büyükkale, Muzaffer Metin, Abdulaziz Kök, Alper Çelikten, Atilla Gürses
Objectives Theoretically, video-assisted mediastinoscopy (VM) should provide a decrease in the incidence of hoarseness in comparison with conventional mediastinoscopy (CM). Methods An investigation of 448 patients with the NSCLC who underwent mediastinoscopy (n = 261 VM, n = 187 CM) between 2006 and 2010. Results With VM, the mean number of sampled LNs and of stations per case were both significantly higher (n = 7.91 ± 1.97 and n = 4.29 ± 0.81) than they were for CM (n = 6...
February 2016: Acta Chirurgica Belgica
J-B Stern, B Wyplosz, P Girard, P Validire, L Escaut, R Caliandro
Endobronchial ultrasonography (EBUS) is a recent mini-invasive technique allowing transbronchial needle aspiration (TBNA) of mediastinal lymph nodes as well as peribronchial lesions. EBUS was initially developed for lung cancer mediastinal staging. Over the years, indications for EBUS have been progressively extended to the scope of inflammatory disorders, mediastinal lymphomas, and infectious diseases. Particularly in immunosuppressed patients, including HIV-infected patients, EBUS allows the diagnosis of several diseases that involve the mediastinum, avoiding invasive surgical explorations such as mediastinoscopy or thoracoscopy...
June 27, 2016: La Revue de Médecine Interne
Jing Xu, Jinglan Zhao, Shaoqing Geng, Q I Wang, Pengfei Wang, Chunling Zhang, Xiongzeng Zhu, Youxin Ji
Primary mediastinal seminoma often occurs in the anterior mediastinum of young males. It is unusual for the tumor to originate in the middle or posterior mediastinum, and such cases have rarely been reported in the English literature. The present study reports the case of a 52-year-old man with a 3.0-cm primary seminoma arising in the middle mediastinum. The patient presented with the symptoms of cough and chest tightness. Fluorine-18 fluorodeoxyglucose-positron emission tomography ((18)F-FDG-PET) scans revealed unique abnormal FDG uptake in the middle mediastinum...
July 2016: Oncology Letters
Ivan H W Yim, Malcolm B Will, Catharine Dhaliwal, Donald M Salter, William S Walker
Intranodal palisaded myofibroblastoma is a rare and benign tumor that usually presents in the inguinal region. We report the case of a 68-year-old woman with a right paratracheal mass and right upper lobe non-small cell lung carcinoma initially staged as T1b N2 M0. After mediastinal staging, the right paratracheal mass was found to be an intranodal palisaded myofibroblastoma, which had caused erroneous upstaging of the lung carcinoma to N2 disease. This had the potential of leading to suboptimal treatment of the primary lung carcinoma if formal mediastinal staging had not been performed...
July 2016: Annals of Thoracic Surgery
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