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Aplastic hypoplastic anaemia

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https://www.readbyqxmd.com/read/25148373/reduced-intensity-stem-cell-allografting-for-pnh-patients-in-the-eculizumab-era-the-mexican-experience
#1
Alejandro Schcolnik-Cabrera, Nancy Labastida-Mercado, Laura Samantha Galindo-Becerra, David Gomez-Almaguer, Miguel Angel Herrera-Rojas, Guillermo Jose Ruiz-Delgado, Guillermo José Ruiz-Arguelles
Background Paroxysmal nocturnal haemoglobinuria (PNH) presents as two major entities: the classical form, predominantly haemolytic and a secondary type with marrow failure and resultant aplastic anaemia (AA-PNH). Currently, the treatment of choice of the haemolytic variant is eculizumab; however, the most frequent form of PNH in México is AA-PNH. Patients and methods Six consecutive AA-PNH patients with HLA-identical siblings were allografted in two institutions in México, employing a reduced-intensity conditioning regimen for stem cell transplantation (RIST) conducted on an outpatient basis...
June 2015: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/23025896/chromosome-anomalies-in-bone-marrow-as-primary-cause-of-aplastic-or-hypoplastic-conditions-and-peripheral-cytopenia-disorders-due-to-secondary-impairment-of-runx1-and-mpl-genes
#2
Cristina Marletta, Roberto Valli, Barbara Pressato, Lydia Mare, Giuseppe Montalbano, Giuseppe Menna, Giuseppe Loffredo, Maria Ester Bernardo, Luciana Vinti, Simona Ferrari, Alessandra Di Cesare-Merlone, Marco Zecca, Francesco Lo Curto, Franco Locatelli, Francesco Pasquali, Emanuela Maserati
UNLABELLED: HASH(0x405c9a8) BACKGROUND: Chromosome changes in the bone marrow (BM) of patients with persistent cytopenia are often considered diagnostic for a myelodysplastic syndrome (MDS). Comprehensive cytogenetic evaluations may give evidence of the real pathogenetic role of these changes in cases with cytopenia without morphological signs of MDS. RESULTS: Chromosome anomalies were found in the BM of three patients, without any morphological evidence of MDS: 1) an acquired complex rearrangement of chromosome 21 in a boy with severe aplastic anaemia (SAA); the rearrangement caused the loss of exons 2-8 of the RUNX1 gene with subsequent hypoexpression...
2012: Molecular Cytogenetics
https://www.readbyqxmd.com/read/22458667/morphological-differentiation-of-severe-aplastic-anaemia-from-hypocellular-refractory-cytopenia-of-childhood-reproducibility-of-histopathological-diagnostic-criteria
#3
MULTICENTER STUDY
Irith Baumann, Monika Führer, Sonja Behrendt, Vit Campr, Judit Csomor, Ingrid Furlan, Valérie de Haas, Gitte Kerndrup, Roos J Leguit, Pascale De Paepe, Peter Noellke, Charlotte Niemeyer, Stephan Schwarz
AIMS: To evaluate the reproducibility and reliability of the histomorphological criteria differentiating severe aplastic anaemia (SAA) and hypoplastic refractory cytopenia of childhood (RCC), the most frequently acquired hypocellular bone marrow conditions of childhood. METHODS AND RESULTS: We performed a double-blind interobserver study of 100 different cases of SAA and RCC among seven haematopathologists of the European Working Group of MDS in Childhood (EWOG-MDS) and the German SAA study...
July 2012: Histopathology
https://www.readbyqxmd.com/read/21196720/second-allogeneic-stem-cell-transplantation-in-a-patient-with-hypoplastic-myelodysplastic-syndrome-following-a-primary-diagnosis-of-aplastic-anaemia
#4
Sunday Ocheni, Anthony Oyekunle, Nicolaus Kröger, Francis Ayuk, Evgeny Klyuchnikov, Soenke Arps, Karsten Held, Tatjana Zabelina, Raissa Adjallé, Christine Wolschke, Axel Rolf Zander, Ulrike Bacher
No abstract text is available yet for this article.
2011: Acta Haematologica
https://www.readbyqxmd.com/read/21065116/hypoplastic-anaemia-treated-with-transfusions-and-folic-acid-fraction
#5
G B PEAT, A BRANCH
No abstract text is available yet for this article.
September 1946: Canadian Medical Association Journal
https://www.readbyqxmd.com/read/20992963/hypoplastic-anaemia
#6
L DODS
No abstract text is available yet for this article.
June 8, 1946: Medical Journal of Australia
https://www.readbyqxmd.com/read/20344526/hypoplastic-anaemia
#7
I A B CATHIE
No abstract text is available yet for this article.
July 1947: Proceedings of the Royal Society of Medicine
https://www.readbyqxmd.com/read/20257630/idiopathic-hypoplastic-anaemia-with-bone-marrow-hyperplasia
#8
E S MILLS
No abstract text is available yet for this article.
September 1947: Canadian Medical Association Journal
https://www.readbyqxmd.com/read/20246633/chronic-hypoplastic-anaemia
#9
L DODS
No abstract text is available yet for this article.
May 17, 1947: Medical Journal of Australia
https://www.readbyqxmd.com/read/18108437/chronic-hypoplastic-anaemia-arising-in-infancy
#10
T ROBSON, P J SWEENEY
No abstract text is available yet for this article.
December 1948: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/15933058/immunosuppressive-therapy-for-aplastic-anemia-in-children-a-more-severe-disease-predicts-better-survival
#11
MULTICENTER STUDY
Monika Führer, Udo Rampf, Irith Baumann, Andreas Faldum, Charlotte Niemeyer, Gritta Janka-Schaub, Wilhelm Friedrich, Wolfram Ebell, Arndt Borkhardt, Christine Bender-Goetze
Severe acquired aplastic anaemia (SAA) is a life-threatening disease characterized by pancytopenia and hypoplastic bone marrow. Autologous T lymphocytes are thought to cause bone marrow failure by immune-mediated excessive apoptosis of stem and progenitor cells. The disease is subclassified into a severe (neutrophil count, > 0.2 x 10(9)/L [> 200/microL]) and a very severe (< 0.2 x 10(9)/L [< 200/microL]) (vSAA) form. We report the results of a prospective multicenter trial with a combined immunosuppressive regimen of cyclosporin A (CSA), anti-thymocyte globulin (ATG) and, in cases with neutrophil counts fewer than 0...
September 15, 2005: Blood
https://www.readbyqxmd.com/read/14331432/a-case-of-idiopathic-hypoplastic-anaemia-in-a-two-year-old-thoroughbred-filly
#12
R K ARCHER, W C MILLER
No abstract text is available yet for this article.
May 8, 1965: Veterinary Record
https://www.readbyqxmd.com/read/14257577/congenital-hypoplastic-anaemia-further-observations-on-a-previously-reported-case
#13
A S PARANDE, K L JAIN
No abstract text is available yet for this article.
January 1965: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/14196246/congenital-hypoplastic-anaemia-pure-red-cell-type
#14
S P KHATUA
No abstract text is available yet for this article.
July 1964: Indian Pediatrics
https://www.readbyqxmd.com/read/14077383/congenital-hypoplastic-anaemia-a-case-report
#15
A S PARANDE, K L JAIN
No abstract text is available yet for this article.
November 1963: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/13900492/congenital-hypoplastic-anaemia-pure-red-cell-anaemia-with-periodic-erythroblastopenia
#16
R R GORDON, S VARADI
No abstract text is available yet for this article.
February 10, 1962: Lancet
https://www.readbyqxmd.com/read/13883718/congenital-hypoplastic-anaemia-with-aminoaciduria-in-a-bantu-infant
#17
J G DAVEL, R E CRONJE
No abstract text is available yet for this article.
March 24, 1962: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/13716634/hypoplastic-anaemia-in-infancy-and-childhood-erythroid-hypoplasia
#18
D W HUGHES
No abstract text is available yet for this article.
August 1961: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/13591300/hypoplastic-anaemia-in-infancy
#19
J L STAFFORD
No abstract text is available yet for this article.
September 1958: Proceedings of the Royal Society of Medicine
https://www.readbyqxmd.com/read/13358241/acquired-haemochromatosis-following-multiple-blood-transfusions-for-hypoplastic-anaemia
#20
P JONES, C D PENGELLY
No abstract text is available yet for this article.
September 1, 1956: Lancet
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