keyword
https://read.qxmd.com/read/38095003/-rnf213-p-r4810k-variant-increases-the-risk-of-vasospastic-angina
#21
JOURNAL ARTICLE
Hiroyuki Ishiyama, Tomotaka Tanaka, Takeshi Yoshimoto, Atsushi Takahashi, Soshiro Ogata, Kunihiro Nishimura, Yoshihiro Asano, Akio Koizumi, Teruo Noguchi, Masafumi Ihara
No abstract text is available yet for this article.
October 2023: JACC Asia
https://read.qxmd.com/read/38094717/diagnosis-and-management-of-vasospastic-angina-in-a-young-woman-wishing-to-become-pregnant
#22
Hirohiko Aikawa, Kota Murai, Chizuko Aoki-Kamiya, Jun Yoshimatsu, Teruo Noguchi
Vasospastic angina can sometimes induce acute myocardial infarction in pregnant women, potentially endangering the lives of mother and child. We describe a case of a young woman with suspected vasospastic angina who wished to become pregnant. Vasospasm provocation testing revealed severe vasospasm, and subsequent appropriate management resulted in successful delivery.
December 6, 2023: JACC. Case reports
https://read.qxmd.com/read/38056914/familial-risk-of-vasospastic-angina-a-nationwide-family-study-in-sweden
#23
JOURNAL ARTICLE
Fabrizio Ricci, Behzad Banihashemi, Mirnabi Pirouzifard, Jan Sundquist, Kristina Sundquist, Richard Sutton, Artur Fedorowski, Bengt Zoller
OBJECTIVES: Vasospastic angina (VSA) is a complex coronary vasomotor disorder associated with an increased risk of myocardial infarction and sudden death. Despite considerable advances in understanding VSA pathophysiology, the interplay between genetic and environmental factors remains elusive. Accordingly, we aimed to determine the familial VSA risk among first-degree relatives of affected individuals. METHODS: A population-based multigenerational cohort study was conducted, including full-sibling pairs born to Swedish parents between 1932 and 2018...
December 6, 2023: Open Heart
https://read.qxmd.com/read/38033437/vasospastic-angina-in-a-young-woman-a-case-report
#24
Misa Yoshida, Yuichi Orita, Chikage Oshita, Yuko Uchimura, Hiroki Teragawa
Vasospastic angina (VSA) is a disease that causes myocardial ischemia due to transient vasoconstriction of the epicardial coronary arteries. This disease generally occurs in middle-aged and older adults, but there are also reports of it occurring in young people. We report a case of VSA in a woman in her 20's. Six months ago, a female patient in her 20s became aware of a strangling sensation in the chest that lasted for approximately 1-20 minutes at rest or during stress. She consulted her family doctor who prescribed nitroglycerin sublingual tablets, which were effective...
November 2023: Curēus
https://read.qxmd.com/read/38016762/severe-hypocalcaemia-mimicking-acute-coronary-syndrome
#25
JOURNAL ARTICLE
Sahitya Allam, Ethan Kotloff, Anusha Bhat, Libin Wang
Hypocalcaemia is a common electrolyte deficiency that can be found in up to 28% of hospitalised patients. It may affect cardiac and smooth muscle tone, leading to ECG abnormalities and, in rare cases, coronary spasms and heart failure. This is a case of a pregnant woman in preterm labour who developed vasospastic angina and corrected QT interval (QTc) prolongation on ECG from severe hypocalcaemia, which likely occurred due to iatrogenic hypermagnesaemia. She had a negative diagnostic workup for acute coronary syndrome, and her chest pain and QTc prolongation ultimately resolved with intravenous electrolyte repletion...
November 28, 2023: BMJ Case Reports
https://read.qxmd.com/read/37954568/successful-detection-of-supraventricular-tachycardia-following-st-elevation-due-to-vasospastic-angina-using-an-insertable-cardiac-monitor-in-a-patient-with-recurrent-syncope-a-case-report
#26
Yuhei Kasai, Junji Morita, Takayuki Kitai, Tsutomu Fujita
No abstract text is available yet for this article.
November 2023: European Heart Journal. Case Reports
https://read.qxmd.com/read/37940795/intraoperative-cardiac-arrest-caused-by-unexpected-vasospastic-angina-requiring-prolonged-resuscitation-using-extracorporeal-membrane-oxygenation-a-case-report
#27
JOURNAL ARTICLE
Shinji Sugita, Masanobu Obata, Fumihiko Hasunuma, Atsuhiro Sakamoto
BACKGROUND: Vasospastic angina (VSA) occurring during surgery is rare but can lead to sudden intraoperative cardiac arrest. CASE PRESENTATION: A 77-year-old man with hypertension, and no history of coronary artery disease, displayed an abrupt ST-segment elevation on the electrocardiogram (ECG) during laparoscopic inguinal hernia surgery under general anesthesia. Subsequently, ventricular fibrillation (VF) occurred, with a finding suggesting ischemic myocardial contracture by transesophageal echocardiography...
November 9, 2023: JA Clinical Reports
https://read.qxmd.com/read/37925046/precision-medicine-in-myocardial-infarction-with-non-obstructive-coronary-disease-minoca-a-comprehensive-review
#28
REVIEW
Laveeza Fatima, Aman Goyal, Shreyas Yakkali, Hritvik Jain, Fatima Ali Raza, Taha Peer, Sai Gautham Kanagala, Amir H Sohail, Jahanzeb Malik
Cardiovascular diseases, particularly myocardial infarction (MI), are a significant cause of mortality globally. Traditional MIs are commonly linked to substantial coronary artery blockage. However, a distinct subset of patients experience MI with non-obstructive coronary arteries, known as MINOCA. Imaging techniques, such as invasive coronary angiograms, are employed to diagnose MI or assess predisposition to one. Coronary angiograms help visualize vessel blockages; however, these blockages are absent in MINOCA cases, posing a diagnostic challenge...
February 2024: Current Problems in Cardiology
https://read.qxmd.com/read/37895453/which-coronary-artery-should-be-preferred-for-starting-the-coronary-spasm-provocation-test
#29
JOURNAL ARTICLE
Hiroki Teragawa, Yuko Uchimura, Chikage Oshita, Yu Hashimoto, Shuichi Nomura
BACKGROUND: The spasm provocation test (SPT) is a critical test for diagnosing vasospastic angina (VSA). However, the choice of vessel to be preferred for initiating the SPT-the right coronary artery (RCA) or the left coronary artery (LCA)-is unclear. This study aimed to assess SPT results including SPT-related complications while initiating the SPT in the RCA and LCA. METHODS: We enrolled 225 patients who underwent coronary angiography and SPTs. The SPT was first performed in the RCA in 133 patients (RCA group) and the LCA in 92 patients (LCA group)...
October 17, 2023: Life
https://read.qxmd.com/read/37891058/pharmacological-coronary-spasm-provocative-testing-in-clinical-practice-a-french-coronary-atheroma-and-interventional-cardiology-group-gaci-position-paper
#30
Fabien Picard, Julien Adjedj, Jean-Philippe Collet, Eric Van Belle, Jacques Monsegu, Bernard Karsenty, Patrick Dupouy, Marine Quillot, Guillaume Bonnet, Alexandre Gautier, Guillaume Cayla, Hakim Benamer
Vasospastic angina, also described as Prinzmetal angina, was first described as a variant form of angina at rest with transient ST-segment elevation; it is common and present in many clinical scenarios, including chronic and acute coronary syndromes, sudden cardiac death, arrhythmia and syncope. However, vasospastic angina remains underdiagnosed, and provocative tests are rarely performed. The gold-standard diagnostic approach uses invasive coronary angiography to induce coronary spasm using ergonovine, methylergonovine or acetylcholine as provocative stimuli...
October 13, 2023: Archives of Cardiovascular Diseases
https://read.qxmd.com/read/37865828/performance-of-intracoronary-and-intravenous-ergonovine-for-diagnostic-of-vasospastic-angina-a-retrospective-analysis-using-propensity-matching
#31
JOURNAL ARTICLE
Pham Vincent, Nathan El Bèze, Arnaud Jegou, Joseph Anconina, Fabien Picard, Dambrin Grégoire
No abstract text is available yet for this article.
September 11, 2023: Coronary Artery Disease
https://read.qxmd.com/read/37842759/endoscopic-thoracic-sympathectomy-in-the-treatment-of-vasospastic-angina-resistant-to-medical-therapy
#32
JOURNAL ARTICLE
Mustafa Azmi Sungur, Gönül Zeren, Mehmet Fatih Yılmaz, İlhan İlker Avcı, Fatma Can, Tuğba Çetin, Aylin Sungur, Ozan Tezen, Enver Yücel, Ali Karagöz, Tamer Okay, Can Yücel Karabay
BACKGROUND: In this study, we aimed to investigate the clinical follow-up results of endoscopic thoracic sympathectomy (ETS) in the treatment of vasospastic angina (VSA) resistant to maximal medical therapy. METHODS: A total of 80 patients with VSA who presented to our hospital between 2010 and 2022 were included in our study. Among them, 6 patients who did not respond to medical therapy underwent ETS. In-hospital and long-term clinical outcomes of patients who underwent ETS were recorded...
October 16, 2023: Anatolian Journal of Cardiology
https://read.qxmd.com/read/37840889/severe-familial-coronary-artery-spasm-in-2-siblings-about-2-cases
#33
Oualid Kerrouani, Raid Faraj, Abderrahmane Bouchaala, Hassan Dib, Nouhaila Lahmouch, Iness Bargach, Ouassima Kihoul, Jamila Zarzur, Mohamed Cherti
Vasospastic angina is the spasm of coronary arteries causing transient myocardial ischemia. VSA is commonly managed with antispasmodic medications including calcium-channel blockers and nitrates. When vasospasm is refractory to conventional medications, unconventional treatment modalities may be used for symptomatic relief. Coronary artery spasm was observed in 2 sisters. Neither of them had significant atheromatous stenosis in the coronary arteries. The 22-year younger sister presented with rest angina in the early morning...
December 2023: Radiology Case Reports
https://read.qxmd.com/read/37813615/a-super-elderly-case-of-suspected-new-onset-vasospastic-angina-complicated-by-myocardial-bridge
#34
JOURNAL ARTICLE
Satoshi Kurisu, Hitoshi Fujiwara
A 90-year-old man experienced chest oppressive sensation at 12:30 AM for the first time. Electrocardiography showed a newly developed inversion of the terminal T-wave in the V2-5 leads. A left coronary angiogram showed no significant atherosclerotic stenosis. A myocardial bridge was found in the mid-left anterior descending artery (LAD). Myocardial scintigraphy with 123 I beta-methyl 15-para-iodophenyl 3(R,S)-methylpentadecanoic acid revealed a reduced uptake in the apical and septal areas. Based on these findings, we suspected new-onset vasospastic angina complicated by a myocardial bridge in the territory of the LAD...
October 6, 2023: Internal Medicine
https://read.qxmd.com/read/37795617/invasive-endotyping-in-patients-with-angina-and-no-obstructive-coronary-artery-disease-a-randomized-controlled-trial
#35
JOURNAL ARTICLE
Novalia P Sidik, Bethany Stanley, Robert Sykes, Andrew J Morrow, Conor P Bradley, Michael McDermott, Thomas J Ford, Giles Roditi, Allister Hargreaves, David Stobo, Jacqueline Adams, John Byrne, Ahmed Mahrous, Robin Young, David Carrick, Ross McGeoch, David Corcoran, Ninian N Lang, Robert Heggie, Olivia Wu, Margaret B McEntegart, Alex McConnachie, Colin Berry
BACKGROUND: We investigated the usefulness of invasive coronary function testing to diagnose the cause of angina in patients with no obstructive coronary arteries. METHODS: Outpatients referred for coronary computed tomography angiography in 3 hospitals in the United Kingdom were prospectively screened. After coronary computed tomography angiography, patients with unobstructed coronary arteries, and who consented, underwent invasive endotyping. The diagnostic assessments included coronary angiography, fractional flow reserve (patient excluded if ≤0...
October 5, 2023: Circulation
https://read.qxmd.com/read/37790002/intraoperative-coronary-spasm-a-potential-case-of-vasospastic-angina
#36
Pedro Camões Correia, Ana Leite, Pedro Alves Marques, Teresa Lugarinho
Prinzmetal's angina typically features spasms of the coronary arteries due to the hyperreactivity of the vascular smooth muscle cells of the vessels to a nonspecific stimulus. Reports of coronary spasm during general anesthesia are rare, but in such cases, diagnosis is suggested by a framework of angina at rest and changes in the electrocardiogram (ECG) or coronary reactivity tests with ergonovine or acetylcholine. The present study describes a case of coronary spasm induced by general anesthesia associated with several cardiovascular risk factors and the usage of vasoactive drugs that was documented by angiography without using stimulating drugs and treated with intracoronary nitroglycerin...
September 2023: Curēus
https://read.qxmd.com/read/37722316/association-of-thyroid-peroxidase-antibody-with-the-rnf213-p-r4810k-variant-in-ischemic-stroke-transient-ischemic-attack
#37
JOURNAL ARTICLE
Takeshi Yoshimoto, Hiroyuki Ishiyama, Yorito Hattori, Kunihiro Nishimura, Yoko Okada, Hideaki Watanabe, Yasumasa Ohyagi, Yasuhisa Akaiwa, Tomoyuki Miyamoto, Michi Kawamoto, Masahiko Ichijo, Hiroyasu Inoue, Noriyuki Matsukawa, Toshiki Mizuno, Hirofumi Matsuyama, Hidekazu Tomimoto, Daisuke Kawakami, Kazunori Toyoda, Masatoshi Koga, Masafumi Ihara
BACKGROUND AND AIMS: RNF213 is a susceptibility gene for moyamoya disease and vasospastic angina, with a second hit considered necessary for their development. Elevated thyroid peroxidase antibody (TPO-Ab) levels have been observed in both diseases, suggesting a possible role of TPO-Ab as a second hit for developing RNF213-related vasculopathy. We investigated the association of TPO-Ab levels with RNF213-related ischemic stroke (IS)/transient ischemic attack (TIA), other than moyamoya disease...
September 12, 2023: Atherosclerosis
https://read.qxmd.com/read/37719976/the-relationships-between-acetylcholine-induced-chest-pain-objective-measures-of-coronary-vascular-function-and-symptom-status
#38
JOURNAL ARTICLE
Steven E S Miner, Mary C McCarthy, Chris I Ardern, Chris G R Perry, Olga Toleva, Lynne E Nield, Cedric Manlhiot, Warren J Cantor
BACKGROUND: Acetylcholine-induced chest pain is routinely measured during the assessment of microvascular function. AIMS: The aim was to determine the relationships between acetylcholine-induced chest pain and both symptom burden and objective measures of vascular function. METHODS: In patients with angina but no obstructive coronary artery disease, invasive studies determined the presence or absence of chest pain during both acetylcholine and adenosine infusion...
2023: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/37719576/understanding-the-link-between-adult-asthma-and-coronary-artery-disease-a-narrative-review
#39
REVIEW
Vasudha S Garg, Mihir H Sojitra, Tyagi J Ubhadiya, Nidhi Dubey, Karan Shah, Siddharth Kamal Gandhi, Priyansh Patel
Asthma is a common pathology worldwide that occurs due to chronic inflammation of the respiratory airways. Persistent pulmonary inflammation leads to low-grade systemic inflammation, influencing blood vessels and triggering coronary artery disease (CAD) events. This review's objectives include discussing the susceptible population for CAD, the mechanism underlying CAD creation in asthma patients, the characteristics of asthma, and the influence of anti-asthmatic medications on CAD development. Adult-onset asthma is strongly linked to CAD and stroke...
August 2023: Curēus
https://read.qxmd.com/read/37718583/st-segment-elevation-myocardial-infarction-and-sudden-cardiac-arrest-due-to-vasospastic-angina-an-underappreciated-challenge
#40
JOURNAL ARTICLE
Jakub Michał Zimodro, Magda Mucha, Aleksandra Chabior, Aleksandra Gasecka, Lukasz Koltowski
No abstract text is available yet for this article.
September 18, 2023: Kardiologia Polska
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