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Gender PCI

Romain Didier, Marco A Magalhaes, Edward Koifman, Florent Leven, Philippe Castellant, Jacques Boschat, Yannic Jobic, Sarkis Kiramijyan, Pierre-Philippe Nicol, Martine Gilard
AIMS: The radiation exposure resulting from cardiovascular procedures may increase the risk of cancer, and/or cause skin injury. Whether the novel cardiovascular automated radiation reduction X-ray system (CARS) can help reduce the patient radiation dose in daily clinical practice remains unknown. The aim of this study was to evaluate the reduction in patient radiation dose with the use of CARS in the cardiac catheterisation laboratory (CCL). METHODS AND RESULTS: This study retrospectively analysed 1,403 consecutives patients who underwent a cardiac catheterisation with coronary angiography (CA) and/or a percutaneous coronary intervention (PCI) in the Brest University Hospital over the course of one year...
October 10, 2016: EuroIntervention
Lucia Barbieri, Monica Verdoia, Matteo Nardin, Paolo Marino, Harry Suryapranata, Giuseppe De Luca
Contrast-induced nephropathy (CIN) is a common complication of coronary angiography/percutaneous coronary intervention (PCI). Identification of high-risk patients and optimal periprocedural management are key points to reduce the incidence of this iatrogenic complication. We evaluated the impact of gender on CIN after coronary angiography/PCI. We enrolled 2851 consecutive patients (730 females and 1851 males) undergoing coronary angiography/PCI. Baseline clinical and procedural characteristics were collected according to gender...
September 22, 2016: Angiology
Michele M Pelter, Denise Loranger, Teri M Kozik, Richard Fidler, Xiao Hu, Mary G Carey
BACKGROUND: Most patients presenting with suspected acute coronary syndrome (ACS) are admitted to telemetry units. While telemetry is an appropriate level of care, acute complications requiring a higher level of care in the intensive care unit (ICU) occur. PURPOSE: Among patients admitted to telemetry for suspected ACS, we determine the frequency of unplanned ICU transfer, and examine whether ECG changes indicative of myocardial ischemia, and/or symptoms preceded unplanned transfer...
August 26, 2016: Journal of Electrocardiology
Long Zhe Guo, Moo Hyun Kim, Chang Heon Shim, Sun Young Choi, Victor L Serebruany
AIMS: Clinical utilization of dual antiplatelet therapy (DAPT) in patients with renal impairment (RI) following percutaneous coronary interventions (PCI) represents an urgent, unmet need choosing optimal agents, duration of treatment, and potential dose/regimen adjustment. The lack of any large randomized trials specifically in RI patients, and the absence of the uniformed clinical data reporting policy, clouds the reality. Moreover, triaging RI patients is problematic due to ongoing kidney deterioration, and the fact that RI patients are prone to both vascular occlusions and bleeding...
July 2016: European Heart Journal. Cardiovascular Pharmacotherapy
Beatrice Ricci, Olivia Manfrini, Edina Cenko, Zorana Vasiljevic, Maria Dorobantu, Sasko Kedev, Goran Davidovic, Marija Zdravkovic, Olivija Gustiene, Božidarka Knežević, Davor Miličić, Lina Badimon, Raffaele Bugiardini
BACKGROUND: Limited data are available on the outcome of primary percutaneous coronary intervention (PCI) in octogenarian patients, as the elderly are under-represented in randomized trials. This study aims to provide insights on clinical characteristics, management and outcome of the elderly and very elderly presenting with STEMI. METHODS: 2225 STEMI patients ≥70years old (mean age 76.8±5.1years and 53.8% men) were admitted into the network of the ISACS-TC registry...
November 1, 2016: International Journal of Cardiology
Wojciech Wanha, Damian Kawecki, Tomasz Roleder, Aleksandra Pluta, Kamil Marcinkiewicz, Beata Morawiec, Mariusz Kret, Tomasz Pawlowski, Grzegorz Smolka, Andrzej Ochala, Wojciech Wojakowski
BACKGROUND: The aim of this study was to evaluate gender differences in the long-term clinical outcomes and safety of patients treated with first- and second-generation DES. METHODS: The Katowice-Zabrze Registry included 1916 consecutive patients treated with either first or second-generation DES. We evaluated major adverse cardiac and cerebral events (MACCE) [composite of death, myocardial infarction (MI), stroke and target vessel revascularization (TVR)] at 12-month follow-up...
July 29, 2016: Scandinavian Cardiovascular Journal: SCJ
Kensuke Takagi, Alaide Chieffo, Joanne Shannon, Toru Naganuma, Satoko Tahara, Yusuke Fujino, Azeem Latib, Matteo Montorfano, Mauro Carlino, Hiroyoshi Kawamoto, Sunao Nakamura, Antonio Colombo
BACKGROUND: Although percutaneous intervention (PCI) for ULM is common, the impact of gender remains unclear. This study aimed to clarify the impact of gender in patients treated with drug-eluting stents (DES) for unprotected left main (ULM) disease. METHODS: Between April 2002 and August 2011, 1026 consecutive patients (212 women and 814 men) undergoing PCI using first or second generation DES for ULM stenosis were analyzed. Study endpoints included major adverse cardiac events (MACE) defined as composite of all-cause death, myocardial infarction (MI), and target lesion revascularization (TLR)...
September 2016: Cardiovascular Revascularization Medicine: Including Molecular Interventions
Jaya Chandrasekhar, Paul Marley, Christopher Allada, Darryl McGill, Simon O'Connor, Moyazur Rahman, Ren Tan, Ata Doost Hosseiny, Bruce Shadbolt, Ahmad Farshid
BACKGROUND: Notwithstanding improvements in door-to-balloon time, adverse event rates after primary PCI have remained steady. We analysed the effect of symptom-to-balloon (STB) time, a reflection of total ischaemic time, on major adverse cardiovascular events (MACE) and explored predictors of prolonged STB time. METHODS: The study population included 1002 consecutive patients (22.4% women) with a mean age of 62.3±13.2 years, who underwent primary PCI during 2008-2014...
June 27, 2016: Heart, Lung & Circulation
Barış Güngör, Mehmet Baran Karataş, Göktürk İpek, Kazım Serhan Özcan, Yiğit Çanga, Tolga Onuk, Muhammed Keskin, Mert İlker Hayıroğlu, Fatma Özpamuk Karadeniz, Aylin Sungur, Recep Öztürk, Osman Bolca
BACKGROUND: Contrast induced nephropathy (CIN) has been proven as a clinical condition related to adverse cardiovascular outcomes. However, relationship between CIN and stent restenosis (SR) remains unclear. In this study, we aimed to investigate the association of CIN with SR rates after primary percutaneous coronary intervention (PCI) and bare metal stent (BMS) implantation. METHODS: A total number of 3225 patients who had undergone primary PCI for STEMI were retrospectively recruited...
September 2016: Renal Failure
Oluwaseyi B Bolorunduro, Adekunle V Kiladejo, Islamiyat Babs Animashaun, Olakunle O Akinboboye
OBJECTIVES: To examine nationwide trends for racial disparities in Percutaneous Coronary Intervention after ST elevated Myocardial Infarction (STEMI). BACKGROUND: The Institute of Medicine (IOM) report published in 2002 showed that African Americans were less likely to receive coronary revascularization such as CABG and stents even after controlling for socioeconomics. It recommended increased awareness of these disparities among health professionals to reduce this...
May 2016: Journal of the National Medical Association
Georgios E Christakopoulos, Dimitri Karmpaliotis, Khaldoon Alaswad, Robert W Yeh, Farouc A Jaffer, R Michael Wyman, William Lombardi, J Aaron Grantham, David A Kandzari, Nicholas Lembo, Jeffrey W Moses, Ajay Kirtane, Manish Parikh, Philip Green, Matthew Finn, Santiago Garcia, Anthony Doing, Mitul Patel, John Bahadorani, Georgios Christopoulos, Aris Karatasakis, Craig A Thompson, Subhash Banerjee, Emmanouil S Brilakis
BACKGROUND: Administration of a large amount of contrast volume during chronic total occlusion (CTO) percutaneous coronary intervention (PCI) may lead to contrast-induced nephropathy. METHODS: We examined the association of clinical, angiographic and procedural variables with contrast volume administered during 1330 CTO-PCI procedures performed at 12 experienced United States centers. RESULTS: Technical and procedural success was 90% and 88%, respectively, and mean contrast volume was 289 ± 138 mL...
July 2016: Journal of Invasive Cardiology
Y M Guo, Z C Zhao, L Zhang, H Z Li, Z Li, H L Sun
The goal of this study was to explore the polymorphisms of CYP2C19 (CYP2C19*2, CYP2C19*3) in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) on clopidogrel therapy in Zhengzhou city for guidance on clinical medication and reduction in the incidence of thromboembolic events. Two hundred and thirty-four ACS patients undergoing PCI were included in the study, including 171 males (average age = 64.13 ± 12 years) and 63 females (average age = 67.86 ± 10.20 years)...
2016: Genetics and Molecular Research: GMR
Martin Kirk Christensen, Hui Huang, Christian Torp-Pedersen, Torleif Trydal, Jan Ravkilde
BACKGROUND: The clinical significance of myocardial infarction related to treatment with percutaneous coronary intervention (PCI) has been subject of great discussion. This subject has been studied for many years using different definitions of peri-procedural myocardial infarction and different biomarkers, the results have varied greatly depending on methods and time of the study. This study was to determine the incidence and prognostic significance of elevated cardiac biomarkers after elective PCI in patients with stable angina pectoris using the current cut-off set by the Third Universal Definition of Myocardial Infarction and current biomarkers...
2016: BMC Cardiovascular Disorders
Vojko Kanic, Maja Vollrath, Franjo Husam Naji, Andreja Sinkovic
BACKGROUND: Data about gender as an independent risk factor for death in ST-elevation myocardial infarction (STEMI) patients is still contrasting. Aim was to assess how gender influences in-hospital and long-term all-cause mortality in STEMI patients with primary percutaneous coronary intervention (PCI) in our region. METHODS: We analysed data from 2069 STEMI patients undergoing primary PCI in our institution from January 2009-December 2014, of whom 28.9% were women...
2016: International Journal of Medical Sciences
Alexandros Papachristidis, Wei Yao Lim, Christos Voukalis, Salma Ayis, Christopher Laing, Roby D Rakhit
BACKGROUND: Renal impairment is a known predictor of mortality in both the general population and in patients with cardiac disease. The aim of this study was to evaluate factors that determine mortality in patients with chronic kidney disease (CKD) who have undergone percutaneous coronary intervention (PCI). METHODS: In this study we included 293 consecutive patients with CKD who underwent PCI between 1st January 2007 and 30th September 2012. The primary outcome that we studied was all-cause mortality in a follow-up period of 12-69 months (mean 38...
May 2016: Cardiorenal Medicine
Yohei Numasawa, Shun Kohsaka, Ikuko Ueda, Hiroaki Miyata, Mitsuaki Sawano, Akio Kawamura, Shigetaka Noma, Masahiro Suzuki, Susumu Nakagawa, Yukihiko Momiyama, Keiichi Fukuda
BACKGROUND: Bleeding complications remain one of the most important challenges in percutaneous coronary intervention (PCI), particularly in Asians who are known to be vulnerable to the use of antiplatelets or anticoagulants. However, the incidence and predictors of bleeding complications after PCI have not been thoroughly investigated in Japan. METHODS: We studied 13,075 consecutive patients in a Japanese multicenter PCI registry (Japan Cardiovascular Database - Keio interhospital Cardiovascular Study: JCD-KiCS) from September 2008 to March 2014...
June 3, 2016: Journal of Cardiology
Baris Gencer, Nicolas Rodondi, Reto Auer, David Nanchen, Lorenz Räber, Roland Klingenberg, Mark Pletscher, Peter Jüni, Stephan Windecker, Christian M Matter, Thomas F Lüscher, François Mach, Thomas V Perneger, François R Girardin
BACKGROUND: Acute coronary syndromes (ACS) have been associated with lower health utilities (HUs) compared with the general population. Given the prognostic improvements after ACS with the implementation of coronary angiography (eg, percutaneous coronary intervention (PCI)), contemporary HU values derived from patient-reported outcomes are needed. METHODS: We analysed data of 1882 patients with ACS 1 year after coronary angiography in a Swiss prospective cohort...
2016: Open Heart
Ahmed Abu-Zaid, Ayman Azzam, Mohammed Abuzaid, Tusneem Elhassan, Naryman Albadawi, Lynn Alkhatib, Osama AlOmar, Abdullah Alsuhaibani, Tarek Amin, Ismail A Al-Badawi
Aim. To report our preliminary single-center experience with cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) for management of peritoneal sarcomatosis (PS). Methods. Eleven patients were retrospectively analyzed for perioperative details. Results. Cytoreduction completeness (CC-0/1) was achieved in all patients with median peritoneal cancer index (PCI) of 14 ± 8.9 (range: 3-29). Combination cisplatin + doxorubicin HIPEC chemotherapy was used in 6 patients. Five patients received intraoperative radiation therapy (IORT)...
2016: Gastroenterology Research and Practice
Hyukjin Park, Hyun Kuk Kim, Myung Ho Jeong, Jae Yeong Cho, Ki Hong Lee, Doo Sun Sim, Nam Sik Yoon, Hyun Ju Yoon, Young Joon Hong, Kye Hun Kim, Hyung Wook Park, Ju Han Kim, Youngkeun Ahn, Jeong Gwan Cho, Jong Chun Park, Young Jo Kim, Myeong Chan Cho, Chong Jim Kim
BACKGROUND: Successful percutaneous coronary intervention (PCI) of the occluded infarct-related artery (IRA) in latecomers may improve long-term survival mainly by reducing left ventricular remodeling. It is not clear whether inhibition of renin-angiotensin system (RAS) brings additional better clinical outcomes in this specific population subset. METHODS: Between January 2008 and June 2013, 669 latecomer patients with acute ST-segment elevation myocardial infarction (STEMI) (66...
April 30, 2016: Journal of Cardiology
Konstantinos C Siontis, Gregory W Barsness, Ryan J Lennon, Jody L Holmen, R Scott Wright, Malcolm R Bell, Bernard J Gersh
The effectiveness of a pharmacoinvasive strategy consisting of fibrinolysis and transfer for percutaneous coronary intervention (PCI) compared to primary PCI (PPCI) in patients presenting to non-PCI-capable hospitals with ST-elevation myocardial infarction (STEMI) is not well defined. We analyzed data from the Mayo Clinic STEMI database of patients treated with a pharmacoinvasive strategy (favored in those presenting early after symptom onset) or PPCI in a regional STEMI network from 2004 to 2012. A total of 364 and 1,337 patients were included in the pharmacoinvasive and PPCI groups, respectively...
June 15, 2016: American Journal of Cardiology
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