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https://www.readbyqxmd.com/read/28072688/factors-associated-with-unattained-ldl-cholesterol-goals-in-chinese-patients-with-acute-coronary-syndrome-one-year-after-percutaneous-coronary-intervention
#1
Wenduo Zhang, Fusui Ji, Xue Yu, Xinyue Wang
Reducing low-density lipoprotein cholesterol (LDL-C) to target ≤1.81 mmol/L is a common therapeutic goal after acute coronary syndrome (ACS). This study aimed to examine the factors associated with reaching or not this LDL-C target after 1 year of optimal statin therapy postpercutaneous coronary intervention (PCI). This was a retrospective study of 633 consecutive prospectively enrolled patients with ACS treated between January 2011 and December 2012 at the Beijing Hospital (China). All patients were treated with PCI and statins for 1 year...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28065620/treatment-response-and-prophylactic-cranial-irradiation-are-prognostic-factors-in-a-real-life-limited-disease-small-cell-lung-cancer-patient-cohort-comprehensively-staged-with-cranial-magnetic-resonance-imaging
#2
Chukwuka Eze, Olarn Roengvoraphoj, Maximilian Niyazi, Guido Hildebrandt, Rainer Fietkau, Claus Belka, Farkhad Manapov
INTRODUCTION: Prophylactic cranial irradiation (PCI) has proven to decrease the incidence of brain metastases (BMs), with a modest improvement in survival. PATIENTS AND METHODS: The impact of PCI was evaluated in 184 patients treated with chemoradiotherapy. PCI was applied to patients with disease with partial and complete response only when cranial magnetic resonance imaging before and after primary treatment revealed no BMs. Correlation between PCI and overall survival (OS), BM-free survival (BMFS), and time to progression (TTP) was analyzed to describe survival within subgroups...
November 21, 2016: Clinical Lung Cancer
https://www.readbyqxmd.com/read/28057001/improved-trends-in-cardiovascular-complications-among-subjects-with-type-2-diabetes-in-korea-a-nationwide-study-2006-2013
#3
Chang Hee Jung, Jin Ook Chung, Kyungdo Han, Seung-Hyun Ko, Kyung Soo Ko, Joong-Yeol Park
BACKGROUND: Representative data on the secular trends in cardiovascular disease (CVD) are limited in Asian populations with diabetes. We aimed to estimate the temporal trends in cardiovascular complications using Korean nationwide whole population-based claims data in subjects with and without diabetes. METHODS: Type 2 diabetes was defined as a current medication history of anti-diabetic drugs and the presence of International Classification of Diseases (ICD)-10 codes (E11-E14) as diagnosis...
January 6, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/28040280/management-and-outcome-of-patients-with-acute-myocardial-infarction-presenting-with-pacemaker-rhythm
#4
Noemi Bertel, Fabienne Witassek, Milo Puhan, Paul Erne, Hans Rickli, Barbara Naegeli, Giovanni Pedrazzini, Jean-Christophe Stauffer, Dragana Radovanovic
BACKGROUND: Diagnosis of acute myocardial infarction (MI) is challenging in pacemaker patients. Little is known about this patient group. METHODS: Patients with MI enrolled in the Swiss national AMIS Plus registry between January 2005 and December 2015 were analyzed. All patients with either paced ventricular rhythm or sinus rhythm with intrinsic ventricular conduction (IVC) were included in this study. Outcomes using crude data and propensity score matching were compared between patients with pacemaker rhythm and patients with IVC...
December 20, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28040190/comparison-of-outcomes-of-women-versus-men-with-non-st-elevation-acute-coronary-syndromes-undergoing-percutaneous-coronary-intervention-from-the-japanese-nationwide-registry
#5
Yohei Numasawa, Taku Inohara, Hideki Ishii, Toshiki Kuno, Masaki Kodaira, Shun Kohsaka, Kenshi Fujii, Shiro Uemura, Tetsuya Amano, Kazushige Kadota, Masato Nakamura
Previous studies have reported that women have worse outcomes than men after percutaneous coronary intervention (PCI), especially in patients with ST-elevation myocardial infarction. However, gender-related differences in patients with non-ST-elevation acute coronary syndromes (NSTE-ACS) have not been thoroughly investigated. In the Japanese nationwide registry, a total of 43,239 patients with NSTE-ACS from 861 hospitals underwent PCI in 2014. Overall, 11,326 patients (26.2%) were women. The women were older (75...
December 18, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/28034708/influence-of-age-and-gender-on-clinical-outcomes-following-percutaneous-coronary-intervention-for-acute-coronary-syndromes
#6
Hanan Idris, John K French, Ibrahim M Shugman, Andrew P Hopkins, Craig P Juergens, Liza Thomas
BACKGROUND: Gender and age are non-modifiable factors influencing clinical outcomes in acute coronary syndromes (ACS). There is evidence that coronary artery disease pathophysiology varies in women. We therefore evaluated the effect of age and gender on clinical outcomes in patients with ACS undergoing percutaneous coronary interventions (PCI). METHODS: Among 3178 (25% female) consecutive ACS patients who underwent PCI at Liverpool Hospital, Sydney from 2003 to 2010, using femoral access in 98% of cases, we determined late events including mortality, myocardial infarction and bleeding according to Bleeding Academic Research Consortium (BARC) criteria...
December 2, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28025925/contemporary-trends-in-oral-antiplatelet-agent-use-in-patients-treated-with-percutaneous-coronary-intervention-for-acute-coronary-syndrome
#7
Kibum Kim, Todd A Lee, Daniel R Touchette, Robert J DiDomenico, Amer K Ardati, Surrey M Walton
BACKGROUND: Recent trials demonstrated the efficacy of prasugrel and ticagrelor compared with clopidogrel in the reduction of cardiovascular complications in patients with acute coronary syndrome (ACS). However, it is unclear how use of the 3 antiplatelet medications has changed in commercially insured patients since the advent of the new agents. OBJECTIVES: To (a) describe the adoption of prasugrel and ticagrelor in patients who received percutaneous coronary intervention (PCI) for the onset of ACS and (b) explore patient factors associated with the selection of the drug to provide insight into utilization patterns of these antiplatelet agents...
January 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/27981260/once-daily-high-dose-radiation-%C3%A2-60-gy-treatment-in-limited-stage-small-cell-lung-cancer
#8
Amir Zahra, Tangel Chang, Taher Abu Hejleh, Muhammad Furqan, Gerald H Clamon, Sudershan K Bhatia, John M Watkins, Sarah L Mott, Logan L Ahmann, Kellie L Bodeker, Douglas R Spitz, John M Buatti, Bryan G Allen
BACKGROUND: To investigate outcomes and prognostic factors in patients treated with once daily high-dose (≥60 Gy) radiation therapy (HDRT) and concurrent platinum-based chemotherapy in limited stage small cell lung cancer (LS-SCLC). While we await current phase III trials to determine optimal radiation dose fractionation schemes in LS-SCLC, we report our experience in LS-SCLC with once daily HDRT. We hypothesized that HDRT would achieve similar efficacy and tolerability as twice daily therapy...
November 2016: J Oncol Transl Res
https://www.readbyqxmd.com/read/27976460/interventional-therapies-and-in-hospital-outcomes-in-acute-coronary-syndromes-complicated-by-von-willebrand-disease
#9
P F Fogarty, A Blair, R Vega, W H Matthai, P A Gimotty
INTRODUCTION: von Willebrand disease (VWD) is one of the most common inherited bleeding disorders. AIM: Investigate the impact of the VWD bleeding tendency on in-hospital management of acute coronary syndromes (ACS). METHODS: Using discharge data from the National Inpatient Sample (NIS), the features of presentation and in-hospital treatment among ACS hospital discharges with and without a VWD diagnosis were investigated. A total of 264 case discharges and 705 860 control discharges were identified...
December 14, 2016: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/27968766/indications-for-fibrinolysis-in-patients-with-st-segment-elevation-myocardial-infarction-from-guidelines-to-practice
#10
C Boivineau, L Orion, J Dimet, E Boiffard
BACKGROUND: European guidelines on managing ST segment elevation myocardial infarction (STEMI) during the first 12hours recommend fibrinolysis when the time elapsing between the first medical contact and balloon time (FMCBT) is more than 120minutes. AIM: To assess the real-life clinical efficacy of guidelines on fibrinolysis in managing STEMI and identify obstacles to their everyday implementation. METHODS: An observational study based on a permanent registry of reperfusion strategies and timing among patients treated in a French general hospital for STEMI with chest pain lasting for less than two hours...
November 2016: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/27923460/comparison-of-characteristics-and-complications-in-men-versus-women-undergoing-chronic-total-occlusion-percutaneous-intervention
#11
Vinoda Sharma, William Wilson, William Smith, Margaret McEntegart, Keith Oldroyd, Novalia Sidik, Alan Bagnall, Mohaned Egred, John Irving, Julian Strange, Thomas Johnson, Simon Walsh, Colm Hanratty, James Spratt
Gender differences exist in clinical outcomes after routine percutaneous coronary intervention (PCI), but studies reporting such outcomes after chronic total occlusion (CTO) PCI are limited. We assessed the characteristics and outcomes of female patients undergoing CTO PCI. We retrospectively analyzed a dedicated national (United Kingdom) prospective CTO database from 2011 to 2015 for outcomes and characteristics of female patients undergoing CTO PCI (unmatched and propensity matched). Female patients constituted 20...
November 16, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27912201/anxiety-levels-of-patients-undergoing-coronary-procedures-in-the-catheterization-laboratory
#12
Ronak Delewi, Wieneke Vlastra, Wim J Rohling, Tineke C Wagenaar, Max Zwemstra, Martin G Meesterman, Marije M Vis, Joanna J Wykrzykowska, Karel T Koch, Robbert J de Winter, Jan Baan, Jan J Piek, Mirjam A G Sprangers, José P S Henriques
BACKGROUND: High levels of anxiety are associated with worse outcomes in coronary artery disease patients. Little is known about anxiety levels in patients undergoing coronary procedures. Our objective is to examine the levels of anxiety in patients undergoing coronary angiography (CAG) or percutaneous coronary intervention (PCI) during the different phases of hospital stay and to evaluate which patient characteristics are associated with increased anxiety. METHODS: Patients undergoing CAG or PCI between April 2009 and April 2010 were included in this prospective cohort study...
February 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27853828/prognostic-role-of-patient-gender-in-limited-disease-small-cell-lung-cancer-treated-with-chemoradiotherapy
#13
Olarn Roengvoraphoj, Chukwuka Eze, Maximilian Niyazi, Minglun Li, Guido Hildebrandt, Rainer Fietkau, Claus Belka, Farkhad Manapov
BACKGROUND: Previous studies have demonstrated that female gender could be a prognostic factor in limited-disease (LD) small-cell lung cancer (SCLC), but the correlation between patient gender and survival parameters remains unclear. PATIENTS AND METHODS: Data from 179 LD SCLC patients treated with definitive chemoradiotherapy (CRT) were reviewed. Influence of patient gender on time to progression (TTP), local control (LC), brain metastasis-free (BMFS), distant metastasis-free (DMFS) and overall survival (OS) was analysed...
November 16, 2016: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/27817847/-chronic-total-occlusions-is-there-a-woman-specificity
#14
F Sanguineti, C Garcia-Alonso, H Benamer, G J Karrillon
Many differences have been reported regarding gender in angioplasty procedures (PCI), but their potential influence on clinical outcomes after CTO PCI has not been elucidated. Aim of this paper is to analyse these potential differences starting from 2 clinical cases. The basic features found in the two clinical cases presented here, older age and presence of diabetes (that are more frequent in women), are in line with the differences identified in non-CTO studies on angioplasty. Furthermore, CTO in women are generally under-diagnosed and less frequently treated by angioplasty than in men...
December 2016: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/27816119/gender-differences-in-outcomes-and-predictors-of-all-cause-mortality-after-percutaneous-coronary-intervention-data-from-united-kingdom-and-sweden
#15
Vijay Kunadian, Weiliang Qiu, Bo Lagerqvist, Nina Johnston, Hannah Sinclair, Ying Tan, Peter Ludman, Stefan James, Giovanna Sarno
To determine gender differences and predictors of all-cause mortality (30 days and 1 year) after percutaneous coronary intervention (PCI) in patients with stable angina pectoris and acute coronary syndrome (non-ST-elevation myocardial infarction/unstable angina pectoris and ST-elevation myocardial infarction) in the British Cardiovascular Intervention Society (BCIS) and Swedish Coronary Angiography and Angioplasty Registry (SCAAR) data sets, an analysis of prospectively collected data from 2007 to 2011 was performed...
January 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/27807732/acute-coronary-syndromes-differences-in-men-and-women
#16
REVIEW
Kris R Kawamoto, Melinda B Davis, Claire S Duvernoy
PURPOSE OF REVIEW: Increased awareness of cardiovascular disease in women has prompted studies to investigate gender-related disparities in acute coronary syndromes (ACSs). In this review, we discuss findings from current literature on the clinical presentation, pathophysiology, diagnosis, and management of ACS in women as compared to men. RECENT FINDINGS: Emerging data show that cardiovascular disease (CVD) continues to be the leading cause of death in women and the annual mortality rate from CVD remains higher in women compared to men...
December 2016: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/27801655/gender-based-differences-in-outcomes-after-orbital-atherectomy-for-the-treatment-of-de-novo-severely-calcified-coronary-lesions
#17
Michael S Lee, Evan Shlofmitz, Pejman Mansourian, Sanjum Sethi, Richard A Shlofmitz
OBJECTIVES: We evaluated the relationship between gender and angiographic and clinical outcomes in patients with severely calcified lesions who underwent orbital atherectomy. BACKGROUND: Female gender is associated with increased risk of adverse clinical events after percutaneous coronary intervention (PCI). Severe coronary artery calcification increases the complexity of PCI and increases the risk of adverse cardiac events. Orbital atherectomy is effective in plaque modification, which facilitates stent delivery and expansion...
November 2016: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27793397/prognostic-significance-of-ischemic-mitral-regurgitation-on-outcomes-in-acute-st-elevation-myocardial-infarction-managed-by-primary-percutaneous-coronary-intervention
#18
Amgad Mentias, Mohammad Q Raza, Amr F Barakat, Elizabeth Hill, Dalia Youssef, Amar Krishnaswamy, Milind Y Desai, Brian Griffin, Stephen Ellis, Venu Menon, E Murat Tuzcu, Samir R Kapadia
Ischemic mitral regurgitation (IMR) has been associated with worse outcome myocardial infarction. However, severity of mitral regurgitation (MR) and its impact on patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) remains unknown. We sought to determine impact of increasing severity of IMR on outcomes in patients with STEMI undergoing primary PCI. All patients presenting with STEMI who underwent primary PCI within 12 hours of symptoms from 1994 to 2014 were included...
January 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/27773911/predictors-of-depression-in-patients-diagnosed-with-myocardial-infarction-after-undergoing-percutaneous-coronary-intervention-a-literature-review
#19
Mana Doi-Kanno, Hiroki Fukahori
AIM: This study identified the factors associated with depression in patients diagnosed with myocardial infarction (MI) who underwent percutaneous coronary intervention (PCI). METHODS: We searched the literature using PubMed and CINAHL from their inception in 1946 to December 2014. The search terms were "myocardial infarction," "depression," and "percutaneous coronary intervention." Studies which investigated factors associated with depression in patients diagnosed with MI who underwent typical medical procedures were searched...
2016: Journal of Medical and Dental Sciences
https://www.readbyqxmd.com/read/27721211/the-utilisation-of-the-cardiovascular-automated-radiation-reduction-x-ray-system-cars-in-the-cardiac-catheterisation-laboratory-aids-in-the-reduction-of-the-patient-radiation-dose
#20
Romain Didier, Marco A Magalhaes, Edward Koifman, Florent Leven, Philippe Castellant, Jacques Boschat, Yannic Jobic, Sarkis Kiramijyan, Pierre-Philippe Nicol, Martine Gilard
AIMS: The radiation exposure resulting from cardiovascular procedures may increase the risk of cancer, and/or cause skin injury. Whether the novel cardiovascular automated radiation reduction X-ray system (CARS) can help reduce the patient radiation dose in daily clinical practice remains unknown. The aim of this study was to evaluate the reduction in patient radiation dose with the use of CARS in the cardiac catheterisation laboratory (CCL). METHODS AND RESULTS: This study retrospectively analysed 1,403 consecutives patients who underwent a cardiac catheterisation with coronary angiography (CA) and/or a percutaneous coronary intervention (PCI) in the Brest University Hospital over the course of one year...
October 10, 2016: EuroIntervention
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