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https://www.readbyqxmd.com/read/29092172/comprehensive-study-of-solid-pharmaceutical-tablets-in-visible-near-infrared-nir-and-longwave-infrared-lwir-spectral-regions-using-a-rapid-simultaneous-ultraviolet-visible-nir-uvn-lwir-laser-induced-breakdown-spectroscopy-linear-arrays-detection-system-and
#1
Clayton S C Yang, Feng Jin, Siva R Swaminathan, Sita Patel, Evan D Ramer, Sudhir B Trivedi, Ei E Brown, Uwe Hommerich, Alan C Samuels
This is the first report of a simultaneous ultraviolet/visible/NIR and longwave infrared laser-induced breakdown spectroscopy (UVN + LWIR LIBS) measurement. In our attempt to study the feasibility of combining the newly developed rapid LWIR LIBS linear array detection system to existing rapid analytical techniques for a wide range of chemical analysis applications, two different solid pharmaceutical tablets, Tylenol arthritis pain and Bufferin, were studied using both a recently designed simultaneous UVN + LWIR LIBS detection system and a fast AOTF NIR (1200 to 2200 nm) spectrometer...
October 30, 2017: Optics Express
https://www.readbyqxmd.com/read/29079404/knowledge-of-appropriate-acetaminophen-use-a-survey-of-college-age-women
#2
Janice L Stumpf, Allison C Liao, Stacy Nguyen, Amy J Skyles, Cesar Alaniz
OBJECTIVES: To evaluate college-age women's knowledge of appropriate doses and potential toxicities of acetaminophen, competency in interpreting Drug Facts label dosing information, and ability to recognize products containing acetaminophen. METHODS: In this cross-sectional prospective study, a 20-item written survey was provided to female college students at a University of Michigan fundraising event in March 2015. RESULTS: A total of 203 female college students, 18-24 years of age, participated in the study...
October 24, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/29034173/mycobacteria-bovis-osteomyelitis-following-intravesical-bcg-for-bladder-cancer
#3
Karan Seegobin, Satish Maharaj, Cherisse Baldeo, Carmen Isache, Bharatsinh Gharia, Lara Zuberi
Mycobacteria Bovis osteomyelitis is a rare adverse effect after Bacillus Calmette-Guerin (BCG) intravesical therapy. A 62-year-old male presented with acute spinal cord compression three months after completing his second course of therapy for bladder cancer. The first course with intravesical BCG was complicated with an episode of hematuria. He reported intermittent subjective fever for 3 weeks thereafter which resolved with Tylenol. Interferon-α2 B was added to the second cycle of intravesical BCG with the indication here being residual tumor, and was tolerated well...
2017: IDCases
https://www.readbyqxmd.com/read/28911028/laundry-blues-a-case-of-methemoglobinemia-with-laundry-detergent-and-tylenol-ingestion
#4
S Pruthi, S Shah, H S Gambhir
No abstract text is available yet for this article.
September 1, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/28825828/electrostatic-constraints-assessed-by-1-h-mas-nmr-illuminate-differences-in-crystalline-polymorphs
#5
Joshua T Damron, Kortney M Kersten, Manoj Kumar Pandey, Kamal H Mroue, Jayasubba Reddy Yarava, Yusuke Nishiyama, Adam J Matzger, Ayyalusamy Ramamoorthy
Atomically resolved crystal structures not only suffer from the inherent uncertainty in accurately locating H atoms but also are incapable of fully revealing the underlying forces enabling the formation of final structures. Therefore, the development and application of novel techniques to illuminate intermolecular forces in crystalline solids are highly relevant to understand the role of hydrogen atoms in structure adoption. Novel developments in (1)H NMR MAS methodology can now achieve robust measurements of (1)H chemical shift anisotropy (CSA) tensors which are highly sensitive to electrostatics...
August 25, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28603351/the-effect-of-balance-taping-for-prevention-of-menstrual-pain-in-female-middle-school-students
#6
Keun-Sang Yum, Sung-Goo Kang, Hyun-Jin Han
[Purpose] The age at menarche in Korean women has been declining sharply. However, for the students who are just beginning to menstruate, taking pain medication might become a long-term habit continuing until adulthood. Therefore, this study investigated whether balance taping would be more helpful than medication in relieving the pain. [Subjects and Methods] Subjects of this study included 125 female students. The participants were assigned to the balance taping group, the control group, and the medication group...
May 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28459825/patterns-of-analgesic-use-to-relieve-tooth-pain-among-residents-in-british-columbia-canada
#7
Jamie Moeller, Julie Farmer, Carlos Quiñonez
The use of prescription opioids has increased dramatically in Canada in recent decades. This rise in opioid prescriptions has been accompanied by increasing rates of opioid-related abuse and addiction, creating serious public health challenges in British Columbia (BC), one of Canada's most populated provinces. Our study explores the relationship between dental pain and prescription opioid use among residents in BC. We used data from the 2003 Canadian Community Health Survey (CCHS), which asked respondents about their use of specific analgesic medications, including opioids, and their history of tooth pain in the past month...
2017: PloS One
https://www.readbyqxmd.com/read/28097095/limited-knowledge-of-acetaminophen-in-patients-with-liver-disease
#8
Sammy Saab, Peter G Konyn, Matthew R Viramontes, Melissa A Jimenez, Jonathan F Grotts, Wally Hamidzadah, Veronica P Dang, Negin L Esmailzadeh, Gina Choi, Francisco A Durazo, Mohamed M El-Kabany, Steven-Huy B Han, Myron J Tong
Background and Aims: Unintentional acetaminophen overdose remains the leading cause of acute liver failure in the United States. Patients with underlying liver disease are at higher risk of poor outcomes from acetaminophen overdose. Limited knowledge of acetaminophen may be a preventable contributor to elevated rates of overdose and thus acute liver failure. The purpose of this study is to assess knowledge of acetaminophen dosing and presence of acetaminophen in common combination products in patients with liver disease...
December 28, 2016: Journal of Clinical and Translational Hepatology
https://www.readbyqxmd.com/read/27767119/antibiotics-are-not-useful-to-reduce-pain-associated-with-irreversible-pulpitis
#9
COMMENT
Eileen Hoskin, Analia Veitz-Keenan
Data sourcesCochrane Oral Health Group's Trials Register, the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, Clinical Trials.gov and the WHO International Clinical Trials Registry Platform. There were no language restrictions.Study selectionRandomised controlled trials which compared the relief of pain with systemic antibiotics and analgesics against placebo and analgesics in the preoperative phase of irreversible pulpitis. The primary interest was pain control with an antibiotic or without one in the presence of analgesics...
2016: Evidence-based Dentistry
https://www.readbyqxmd.com/read/27440277/intestinal-lymphangiectasia-insights-on-management-and-literature-review
#10
REVIEW
Mohamad J Alshikho, Joud M Talas, Salem I Noureldine, Saf Zazou, Aladdin Addas, Haitham Kurabi, Mahmoud Nasser
BACKGROUND Intestinal lymphangiectasia (IL) is a rare disease characterized by a dilatation of the intestinal lymphatics and loss of lymph fluid into the gastrointestinal tract leading to hypoproteinemia, edema, lymphocytopenia, hypogammaglobinemia, and immunological abnormalities. Iron, calcium, and other serum components (e.g., lipids, fat soluble vitamins) may also be depleted. A literature search revealed more than 200 reported cases of IL. Herein, we report our observations of a patient diagnosed with IL; we also present our conclusion for our review of the published literature...
July 21, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27365868/change-in-prescription-habits-after-federal-rescheduling-of-hydrocodone-combination-products
#11
Susan Seago, Adam Hayek, Jessica Pruszynski, Megan Greene Newman
Nationally, health care providers wrote 259 million prescriptions for narcotic analgesics in 2012, or roughly one bottle of narcotics per US adult (1). In an effort to combat this ever-growing problem, the Drug Enforcement Administration changed the schedule of hydrocodone combination products from schedule III to schedule II on October 6, 2014. Fourteen Baylor Scott & White pharmacies encompassing a 200-mile radius in Central Texas were queried for prescription information on hydrocodone/acetaminophen, morphine, codeine/acetaminophen, and tramadol before and after the rescheduling to evaluate trends in prescription drug usage...
July 2016: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/26886473/antibiotic-use-for-irreversible-pulpitis
#12
REVIEW
Anirudha Agnihotry, Zbys Fedorowicz, Esther J van Zuuren, Allan G Farman, Jassim Hasan Al-Langawi
BACKGROUND: Irreversible pulpitis, which is characterised by acute and intense pain, is one of the most frequent reasons that patients attend for emergency dental care. Apart from removal of the tooth, the customary way of relieving the pain of irreversible pulpitis is by drilling into the tooth, removing the inflamed pulp (nerve) and cleaning the root canal. However, a significant number of dentists continue to prescribe antibiotics to stop the pain of irreversible pulpitis.This review updates the previous version published in 2013...
February 17, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26254283/prenatal-acetaminophen-affects-maternal-immune-and-endocrine-adaptation-to-pregnancy-induces-placental-damage-and-impairs-fetal-development-in-mice
#13
Kristin Thiele, M Emilia Solano, Samuel Huber, Richard A Flavell, Timo Kessler, Roja Barikbin, Roman Jung, Khalil Karimi, Gisa Tiegs, Petra C Arck
Acetaminophen (APAP; ie, Paracetamol or Tylenol) is generally self-medicated to treat fever or pain and recommended to pregnant women by their physicians. Recent epidemiological studies reveal an association between prenatal APAP use and an increased risk for asthma. Our aim was to identify the effects of APAP in pregnancy using a mouse model. Allogeneically mated C57Bl/6J females were injected i.p. with 50 or 250 mg/kg APAP or phosphate-buffered saline on gestation day 12.5; nonpregnant females served as controls...
October 2015: American Journal of Pathology
https://www.readbyqxmd.com/read/25862546/over-the-counter-relief-from-pains-and-pleasures-alike-acetaminophen-blunts-evaluation-sensitivity-to-both-negative-and-positive-stimuli
#14
RANDOMIZED CONTROLLED TRIAL
Geoffrey R O Durso, Andrew Luttrell, Baldwin M Way
Acetaminophen, an effective and popular over-the-counter pain reliever (e.g., the active ingredient in Tylenol), has recently been shown to blunt individuals' reactivity to a range of negative stimuli in addition to physical pain. Because accumulating research has shown that individuals' reactivity to both negative and positive stimuli can be influenced by a single factor (an idea known as differential susceptibility), we conducted two experiments testing whether acetaminophen blunted individuals' evaluations of and emotional reactions to both negative and positive images from the International Affective Picture System...
June 2015: Psychological Science
https://www.readbyqxmd.com/read/25112303/impact-of-educational-levels-and-health-literacy-on-community-acetaminophen-knowledge
#15
Eric J Ip, Terrill T-L Tang, Vincent Cheng, Junhua Yu, Derren S Cheongsiatmoy
Patient understanding of acetaminophen is important for its safe and appropriate self-use. A cross-sectional survey was conducted in the San Francisco Bay Area to determine the impact of educational level, patient health literacy score, and other demographic characteristics on acetaminophen knowledge. A 17-item, in-person, paper-and-pen questionnaire containing questions about demographics and acetaminophen knowledge was administered to 311 adults outside 5 local grocery stores in varying socioeconomic communities...
December 2015: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/25004022/acetaminophen-and-meloxicam-inhibit-platelet-aggregation-and-coagulation-in-blood-samples-from-humans
#16
Angela K Martini, Cassandra M Rodriguez, Andrew P Cap, Wenjun Z Martini, Michael A Dubick
Acetaminophen (Ace) and meloxicam (Mel) are the two types of analgesic and antipyretic medications. This study investigated the dose responses of acetaminophen and meloxicam on platelet aggregation and coagulation function in human blood samples. Blood samples were collected from six healthy humans and processed to make platelet-adjusted (100 × 10 cells/μl) blood samples. Acetaminophen (Tylenol, Q-PAP, 100 mg/ml) was added at the doses of 0 μg/ml (control), 214 μg/ml (the standard dose, 1 ×), 4 ×, 8 ×, 10 ×, 12 ×, 16 ×, and 20 ×...
December 2014: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/24813653/patient-perception-and-knowledge-of-acetaminophen-in-a-large-family-medicine-service
#17
Christopher M Herndon, Dawn M Dankenbring
The use of acetaminophen is currently under increased scrutiny by the US Food and Drug Administration (FDA) due to the risk of intentional and more concerning, unintentional overdose-related hepatotoxicity. Acetaminophen is responsible for an estimated 48% of all acute liver failure diagnoses. The purpose of this study is to evaluate patient perception and knowledge of the safe use and potential toxicity of acetaminophen-containing products. The authors conducted a descriptive, 2-week study using a convenience sample from a large family medicine clinic waiting room...
June 2014: Journal of Pain & Palliative Care Pharmacotherapy
https://www.readbyqxmd.com/read/24763167/insufficient-evidence-to-assess-the-effectiveness-of-antibiotics-for-irreversible-pulpitis
#18
COMMENT
Roy George
DATA SOURCES: The Cochrane Oral Health Group's Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase and the US National Institutes of Health Trials Register. STUDY SELECTION: Randomised controlled trials (RCTs) which compared pain relief with systemic antibiotics and analgesics, against placebo and analgesics in the acute preoperative phase of irreversible pulpitis. DATA EXTRACTION AND SYNTHESIS: Study selection, risk of bias assessment and data extraction were carried out independently by two reviewers...
March 2014: Evidence-based Dentistry
https://www.readbyqxmd.com/read/24628747/randomized-clinical-trial-of-hydrocodone-acetaminophen-versus-codeine-acetaminophen-in-the-treatment-of-acute-extremity-pain-after-emergency-department-discharge
#19
RANDOMIZED CONTROLLED TRIAL
Andrew K Chang, Polly E Bijur, Kevin G Munjal, E John Gallagher
OBJECTIVES: The objective was to test the hypothesis that hydrocodone/acetaminophen (Vicodin [5/500]) provides more efficacious analgesia than codeine/acetaminophen (Tylenol #3 [30/300]) in patients discharged from the emergency department (ED). Both are currently Drug Enforcement Administration (DEA) Schedule III narcotics. METHODS: This was a prospective, randomized, double-blind, clinical trial of patients with acute extremity pain who were discharged home from the ED, comparing a 3-day supply of oral hydrocodone/acetaminophen (5 mg/500 mg) to oral codeine/acetaminophen (30 mg/300 mg)...
March 2014: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/24604434/a-triple-option-analgesia-plan-for-tactical-combat-casualty-care-tccc-guidelines-change-13-04
#20
Frank K Butler, Russ S Kotwal, Chester C Buckenmaier, Erin P Edgar, Kevin C O'Connor, Harold R Montgomery, Stacy A Shackelford, John V Gandy, Ian S Wedmore, Jeffrey W Timby, Kirby R Gross, Jeffrey A Bailey
Although the majority of potentially preventable fatalities among U.S. combat forces serving in Afghanistan and Iraq have died from hemorrhagic shock, the majority of U.S. medics carry morphine autoinjectors for prehospital battlefield analgesia. Morphine given intramuscularly has a delayed onset of action and, like all opioids, may worsen hemorrhagic shock. Additionally, on a recent assessment of prehospital care in Afghanistan, combat medical personnel noted that Tactical Combat Casualty Care (TCCC) battlefield analgesia recommendations need to be simplified--there are too many options and not enough clear guidance on which medication to use in specific situations...
2014: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
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