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https://www.readbyqxmd.com/read/29131491/the-polygonal-model-a-simple-representation-of-biomolecules-as-a-tool-for-teaching-metabolism
#1
Carlos Francisco Sampaio Bonafe, Jose Ailton Conceição Bispo, Marcelo Bispo de Jesus
Metabolism involves numerous reactions and organic compounds that the student must master to understand adequately the processes involved. Part of biochemical learning should include some knowledge of the structure of biomolecules, although the acquisition of such knowledge can be time-consuming and may require significant effort from the student. In this report, we describe the "polygonal model" as a new means of graphically representing biomolecules. This model is based on the use of geometric figures such as open triangles, squares, and circles to represent hydroxyl, carbonyl, and carboxyl groups, respectively...
November 13, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/29101533/efficacy-of-a-sheet-combined-with-fibrin-glue-in-repair-of-pleural-defect-at-the-early-phase-after-lung-surgery-in-a-canine-model
#2
Takashi Sakai, Noriyuki Matsutani, Eiichi Kanai, Yoshikane Yamauchi, Hirofumi Uehara, Hisae Iinuma, Masafumi Kawamura
OBJECTIVE: Polyglycolic acid and oxidized regenerated cellulose have been widely used as a sealant for repairing pulmonary air leakage during respiratory surgery. However, fundamental research of these materials has not been sufficiently conducted. Therefore, we conducted studies to assess the pressure resistance ability of these materials using a canine visceral pleural defect model at the early phase. METHOD: The 6-mm circular defect and the 12-mm square defect were created on the visceral pleura of anesthetized beagles...
November 3, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29092503/assessing-the-degradation-of-compliant-electrodes-for-soft-actuators
#3
Samuel Rosset, Christine de Saint-Aubin, Alexandre Poulin, Herbert R Shea
We present an automated system to measure the degradation of compliant electrodes used in dielectric elastomer actuators (DEAs) over millions of cycles. Electrodes for DEAs generally experience biaxial linear strains of more than 10%. The decrease in electrode conductivity induced by this repeated fast mechanical deformation impacts the bandwidth of the actuator and its strain homogeneity. Changes in the electrode mechanical properties lead to reduced actuation strain. Rather than using an external actuator to periodically deform the electrodes, our measurement method consists of measuring the properties of an electrode in an expanding circle DEA...
October 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/29059508/large-scale-long-range-ordered-patterning-of-nanocrystals-via-capillary-bridge-manipulation
#4
Jiangang Feng, Qian Song, Bo Zhang, Yuchen Wu, Tie Wang, Lei Jiang
Deterministic assembly of nanoparticles with programmable patterns is a core opportunity for property-by-design fabrication and large-scale integration of functional materials and devices. The wet-chemical-synthesized colloidal nanocrystals are compatible with solution assembly techniques, thus possessing advantages of high efficiency, low cost, and large scale. However, conventional solution process suffers from tradeoffs between spatial precision and long-range order of nanocrystal assembly arising from the uncontrollable dewetting dynamics and fluid flow...
October 23, 2017: Advanced Materials
https://www.readbyqxmd.com/read/29030759/localizing-semantic-interference-from-distractor-sounds-in-picture-naming-a-dual-task-study
#5
Andreas Mädebach, Marie-Luise Kieseler, Jörg D Jescheniak
In this study we explored the locus of semantic interference in a novel picture-sound interference task in which participants name pictures while ignoring environmental distractor sounds. In a previous study using this task (Mädebach, Wöhner, Kieseler, & Jescheniak, in Journal of Experimental Psychology: Human Perception and Performance, 43, 1629-1646, 2017), we showed that semantically related distractor sounds (e.g., BARKINGdog) interfere with a picture-naming response (e.g., "horse") more strongly than unrelated distractor sounds do (e...
October 13, 2017: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/28988643/a-novel-fitting-algorithm-for-alignment-curve-radius-estimation-using-corneal-elevation-data-in-orthokeratology-lens-trial
#6
Lu Zhang, Yue Zhang, Yanlin Liu, Kai Wang, Mingwei Zhao
PURPOSE: To evaluate a novel fitting algorithm for estimation of alignment curve (AC) radius during orthokeratology lens trial. METHODS: Fifty myopic children were recruited in this study. AC radii were estimated by both traditional method using flat K readings and eccentricity values and by a novel fitting algorithm, which was composed of 256 circle fittings using corneal elevation data from the corresponding AC region and a succedent toric fitting based on these calculated AC curvatures...
October 4, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28982874/impact-of-calgb-9343-trial-and-sociodemographic-variation-on-patterns-of-adjuvant-radiation-therapy-practice-for-elderly-women-%C3%A2-70-years-with-stage-i-estrogen-receptor-positive-breast-cancer-analysis-of-the-national-cancer-data-base
#7
Quyen D Chu, Meijiao Zhou, Kaelen L Medeiros, Prakash Peddi, Xiao Cheng Wu
BACKGROUND: The Cancer and Leukemia Group B (CALGB) 9343 trial demonstrated that adjuvant radiation therapy (RT) can be omitted in women 70 years or older, with small (≤2 cm), negative lymph nodes, estrogen receptor (ER)-positive breast cancer. We examined whether RT usage following the CALGB publication had decreased over time and evaluated sociodemographic and clinical factors associated with RT omission. MATERIALS AND METHODS: From the National Cancer Data Base, we analyzed a cohort of 120,308 women aged 70 years or older with stage I, ER-positive breast cancer who underwent lumpectomy...
October 2017: Anticancer Research
https://www.readbyqxmd.com/read/28967787/more-than-a-filter-feature-based-attention-regulates-the-distribution-of-visual-working-memory-resources
#8
Blaire Dube, Stephen M Emrich, Naseem Al-Aidroos
Across 2 experiments we revisited the filter account of how feature-based attention regulates visual working memory (VWM). Originally drawing from discrete-capacity ("slot") models, the filter account proposes that attention operates like the "bouncer in the brain," preventing distracting information from being encoded so that VWM resources are reserved for relevant information. Given recent challenges to the assumptions of discrete-capacity models, we investigated whether feature-based attention plays a broader role in regulating memory...
October 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/28962833/cell-micropatterning-reveals-the-modulatory-effect-of-cell-shape-on-proliferation-through-intracellular-calcium-transients
#9
Jie Tong, Ying Qi, Xiangmiao Wang, Liyin Yu, Chang Su, Wenjun Xie, Jianbao Zhang
The mechanism by which cell shape regulates the function of the cell is one of the most important biological issues, but it remains unclear. Here, we investigated the effect of the regulation of cell shape on proliferation by using a micropatterning approach to confine MC3T3-E1 cells into specific shapes. Our results show that the proliferation rate for rectangle-, triangle-, square- and circle-shaped osteoblasts increased sequentially and was related to the nuclear shape index (NSI) but not the cell shape index (CSI)...
December 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28953765/when-asperger-s-disorder-came-out
#10
Chloe Gamlin
BACKGROUND: In 2013, the American Psychiatric Association removed Asperger's Disorder from the DSM, offering instead the new DSM-5 diagnosis: Autism Spectrum Disorder. This change has been hailed the most controversial exclusion from the DSM, yet unlike the 1973 removal of homosexuality from DSM-III, Asperger's disorder has not been demedicalised. Rather, the disorder has simply been reclassified as part of the DSM-5 Autism Spectrum and therefore retains its fundamental characteristic as a mental disorder owing to its inclusion within the sphere of the DSM...
September 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28890683/rapid-processing-of-a-global-feature-in-the-on-visual-pathways-of-behaving-monkeys
#11
Jun Huang, Yan Yang, Ke Zhou, Xudong Zhao, Quan Zhou, Hong Zhu, Yingshan Yang, Chunming Zhang, Yifeng Zhou, Wu Zhou
Visual objects are recognized by their features. Whereas, some features are based on simple components (i.e., local features, such as orientation of line segments), some features are based on the whole object (i.e., global features, such as an object having a hole in it). Over the past five decades, behavioral, physiological, anatomical, and computational studies have established a general model of vision, which starts from extracting local features in the lower visual pathways followed by a feature integration process that extracts global features in the higher visual pathways...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28888154/factors-associated-with-an-evidence-based-measure-of-implementation-for-the-adolescent-community-reinforcement-approach
#12
Bryan R Garner, Sarah B Hunter, Mary E Slaughter, Bing Han, Susan H Godley
BACKGROUND: An evidence-based measure of implementation (EBMI) is an implementation outcome measure shown to have predictive validity with one or more future-measured constructs of importance. The current study sought to identify correlates and predictors of an EBMI called procedure exposure. Garner et al. (2016) found procedure exposure to be an EBMI for the Adolescent Community Reinforcement Approach (A-CRA). METHODS: The dataset included 76 community-based substance use treatment organizations located across the United States...
November 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28880726/parents-spatial-language-mediates-a-sex-difference-in-preschoolers-spatial-language-use
#13
Shannon M Pruden, Susan C Levine
Do boys produce more terms than girls to describe the spatial world-that is, dimensional adjectives (e.g., big, little, tall, short), shape terms (e.g., circle, square), and words describing spatial features and properties (e.g., bent, curvy, edge)? If a sex difference in children's spatial-language use exists, is it related to the spatial language that parents use when interacting with children? We longitudinally tracked the development of spatial-language production in children between the ages of 14 and 46 months in a diverse sample of 58 parent-child dyads interacting in their homes...
November 2017: Psychological Science
https://www.readbyqxmd.com/read/28807732/diagnostic-capability-of-peripapillary-three-dimensional-retinal-nerve-fiber-layer-volume-for-glaucoma-using-optical-coherence-tomography-volume-scans
#14
Ziad Khoueir, Firas Jassim, Linda Yi-Chieh Poon, Edem Tsikata, Geulah S Ben-David, Yingna Liu, Eric Shieh, Ramon Lee, Rong Guo, Georgia Papadogeorgou, Boy Braaf, Huseyin Simavli, Christian Que, Benjamin J Vakoc, Brett E Bouma, Johannes F de Boer, Teresa C Chen
PURPOSE: To determine the diagnostic capability of peripapillary 3-dimensional (3D) retinal nerve fiber layer (RNFL) volume measurements from spectral-domain optical coherence tomography (OCT) volume scans for open-angle glaucoma (OAG). DESIGN: Assessment of diagnostic accuracy. METHODS: Setting: Academic clinical setting. STUDY POPULATION: Total of 180 patients (113 OAG and 67 normal subjects). OBSERVATION PROCEDURES: One eye per subject was included...
October 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28737930/self-collapse-lithography
#15
Chuanzhen Zhao, Xiaobin Xu, Qing Yang, Tianxing Man, Steven J Jonas, Jeffrey J Schwartz, Anne M Andrews, Paul S Weiss
We report a facile, high-throughput soft lithography process that utilizes nanoscale channels formed naturally at the edges of microscale relief features on soft, elastomeric stamps. Upon contact with self-assembled monolayer (SAM) functionalized substrates, the roof of the stamp collapses, resulting in the selective removal of SAM molecules via a chemical lift-off process. With this technique, which we call self-collapse lithography (SCL), sub-30 nm patterns were achieved readily using masters with microscale features prepared by conventional photolithography...
July 31, 2017: Nano Letters
https://www.readbyqxmd.com/read/28724444/adaptation-effects-in-static-postural-control-by-providing-simultaneous-visual-feedback-of-center-of-pressure-and-center-of-gravity
#16
Kenta Takeda, Hiroki Mani, Naoya Hasegawa, Yuki Sato, Shintaro Tanaka, Hiroshi Maejima, Tadayoshi Asaka
BACKGROUND: The benefit of visual feedback of the center of pressure (COP) on quiet standing is still debatable. This study aimed to investigate the adaptation effects of visual feedback training using both the COP and center of gravity (COG) during quiet standing. METHODS: Thirty-four healthy young adults were divided into three groups randomly (COP + COG, COP, and control groups). A force plate was used to calculate the coordinates of the COP in the anteroposterior (COPAP) and mediolateral (COPML) directions...
July 19, 2017: Journal of Physiological Anthropology
https://www.readbyqxmd.com/read/28707348/regulation-of-cell-arrangement-using-a-novel-composite-micropattern
#17
Xiaoyi Liu, Yaoping Liu, Feng Zhao, Tingting Hun, Shan Li, Yuguang Wang, Weijie Sun, Wei Wang, Yan Sun, Yubo Fan
Micropatterning technique has been used to control single cell geometry in many researches, however, this is no report that it is used to control multicelluar geometry, which not only control single cell geometry but also organize those cells by a certain pattern. In this work, a composite protein micropattern is developed to control both cell shape and cell location simultaneously. The composite micropattern consists of a central circle 15 μm in diameter for single-cell capture, surrounded by small, square arrays (3 μm × 3 μm) for cell spreading...
July 13, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28700499/cerebrovascular-risk-factors-for-patients-with-cerebral-watershed-infarction-a-case-control-study-based-on-computed-tomography-angiography-in-a-population-from-southwest-china
#18
Mei-Xue Dong, Ling Hu, Yuan-Jun Huang, Xiao-Min Xu, Yang Liu, You-Dong Wei
To determine cerebrovascular risk factors for patients with cerebral watershed infarction (CWI) from Southwest China.Patients suffering from acute ischemic stroke were categorized into internal CWI (I-CWI), external CWI (E-CWI), or non-CWI (patients without CWI) groups. Clinical data were collected and degrees of steno-occlusion of all cerebral arteries were scored. Arteries associated with the circle of Willis were also assessed. Data were compared using Pearson chi-squared tests for categorical data and 1-way analysis of variance with Bonferroni post hoc tests for continuous data, as appropriate...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28637337/matrix-completion-with-side-information-and-its-applications-in-predicting-the-antigenicity-of-influenza-viruses
#19
Li Huang, Xianhong Li, Pengfei Guo, Yuhua Yao, Bo Liao, Weiwei Zhang, Fayou Wang, Jiasheng Yang, Yulong Zhao, Hailiang Sun, Pingan He, Jialiang Yang
Motivation: Low-rank matrix completion has been demonstrated to be powerful in predicting antigenic distances among influenza viruses and vaccines from partially revealed hemagglutination inhibition (HI) table. Meanwhile, influenza hemagglutinin (HA) protein sequences are also effective in inferring antigenic distances. Thus, it is natural to integrate HA protein sequence information into low-rank matrix completion model to help infer influenza antigenicity, which is critical to influenza vaccine development...
June 16, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28602330/mean-shape-of-the-human-limbus
#20
Alejandra Consejo, Clara Llorens-Quintana, Hema Radhakrishnan, D Robert Iskander
PURPOSE: To characterize the mean topographic shape of the limbus of a normal human eye and determine whether it depends on age or refractive power. SETTING: University of Manchester, Manchester, United Kingdom. DESIGN: Prospective case series. METHODS: Participants with no previous ocular surgeries were included in this study. The left eye was measured with a corneoscleral topographer (Eye Surface Profiler). From the raw anterior eye height data, the topographic limbus was demarcated and fitted in 3 dimensions to a circle, an ellipse, and a Fourier series...
May 2017: Journal of Cataract and Refractive Surgery
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