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Cerebral palsy

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https://www.readbyqxmd.com/read/27930523/anterior-cervical-discectomy-and-fusion-versus-anterior-cervical-corpectomy-and-fusion-in-multilevel-cervical-spondylotic-myelopathy-a-meta-analysis
#1
Tao Wang, Hui Wang, Sen Liu, Huang-Da An, Huan Liu, Wen-Yuan Ding
BACKGROUND: Both anterior cervical discectomy and fusion (ACDF) and anterior cervical corpectomy and fusion (ACCF) are used to treat multilevel cervical spondylotic myelopathy (mCSM); however, which one is better treatment for mCSM remains considerable controversy. A meta-analysis was performed to compare clinical outcomes, radiographic outcomes, and surgical outcomes between ACDF and ACCF in treatment for mCSM. METHODS: An extensive search of literature was performed in Pubmed/MEDLINE, Embase, the Cochrane library, CNKI, and WANFANG databases on ACDF versus ACCF treatment for mCSM from January 2011 to August 2016...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27928378/sixth-nerve-palsy-in-paediatric-intracranial-hypertension
#2
Julia E Reid, Rachel E Reem, Shawn C Aylward, David L Rogers
The purpose of this study was to report the incidence and describe the characteristics of sixth cranial nerve (CN VI) palsy in paediatric patients with intracranial hypertension (IH). A retrospective chart review of central Ohio children diagnosed with IH over the 3-year period from 2010 to 2013 was conducted. IH without identifiable cause was defined as idiopathic intracranial hypertension (IIH), whereas IH with identifiable pathologic aetiology was deemed secondary intracranial hypertension (SIH). A subset of patients with CN VI palsy was identified...
February 2016: Neuro-ophthalmology
https://www.readbyqxmd.com/read/27927938/transcranial-direct-current-stimulation-for-children-with-perinatal-stroke-and-hemiparesis
#3
Adam Kirton, Patrick Ciechanski, Ephrem Zewdie, John Andersen, Alberto Nettel-Aguirre, Helen Carlson, Lisa Carsolio, Mia Herrero, Jillian Quigley, Aleksandra Mineyko, Jacquie Hodge, Michael Hill
OBJECTIVE: To determine whether the addition of transcranial direct current stimulation (tDCS) to intensive therapy increases motor function in children with perinatal stroke and hemiparetic cerebral palsy. METHODS: This was a randomized, controlled, double-blind clinical trial. Participants were recruited from a population-based cohort with MRI-classified unilateral perinatal stroke, age of 6 to 18 years, and disabling hemiparesis. All completed a goal-directed, peer-supported, 2-week after-school motor learning camp (32 hours of therapy)...
December 7, 2016: Neurology
https://www.readbyqxmd.com/read/27927506/correction-of-pelvic-obliquity-after-spinopelvic-fixation-in-children-with-cerebral-palsy-a-comparison-study-with-minimum-two-year-follow-up
#4
Oussama Abousamra, Tristan Nishnianidze, Kenneth J Rogers, Ilhan A Bayhan, Petya Yorgova, Suken A Shah
STUDY DESIGN: Single institution cohort data were collected prospectively and reviewed retrospectively. OBJECTIVES: This study aims to compare outcomes among three different instrumentation types: unit rod, iliac screws, and sacral alar iliac (SAI) screws in terms of pelvic obliquity correction in children with cerebral palsy (CP). SUMMARY OF BACKGROUND DATA: The optimal choice for spinopelvic fixation in CP scoliosis with pelvic obliquity is controversial...
May 2016: Spine Deformity
https://www.readbyqxmd.com/read/27927033/effects-of-lateral-electrical-surface-stimulation-on-scoliosis-in-children-with-severe-cerebral-palsy-a-pilot-study
#5
Eun Jae Ko, In Young Sung, Gi Jeong Yun, Jung-A Kang, JaYoung Kim, Go Eun Kim
PURPOSE: To evaluate the effects of lateral electrical surface stimulation (LESS) on scoliosis and trunk balance in children with severe cerebral palsy (CP). METHODS: Children with severe CP (GMFCS level IV or V) and stationary or progressive scoliosis were enrolled. Children were recommended of two sessions of LESS/day, 1 h/session, for 3 months at home: at 40-80 mA intensity, 200 μs pulse width, 25 Hz frequency, on for 6 s and then off for 6 s on the convex side of the trunk curve...
December 7, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27927029/measuring-wearing-time-of-knee-ankle-foot-orthoses-in-children-with-cerebral-palsy-comparison-of-parent-report-and-objective-measurement
#6
Josina C Maas, Annet J Dallmeijer, Bodil Y Oudshoorn, Eline A M Bolster, Peter A Huijing, Richard T Jaspers, Jules G Becher
: Purpose state: Orthotic wearing time may be an important confounder in efficacy studies of treatment in children with spastic cerebral palsy (SCP). Most studies measure parent-reported wearing time (WTparent) with questionnaires, but it is questionable whether this yields valid results. This study aims to compare WTparent with objectively measured wearing time (WTobj) in children with SCP receiving orthotic treatment. METHOD: Eight children with SCP participated in this observational study...
December 7, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27925397/both-pharyngeal-and-esophageal-phases-of-swallowing-are-associated-with-recurrent-pneumonia-in-pediatric-patients
#7
Selen Serel Arslan, Numan Demir, Aynur Ayşe Karaduman
INTRODUCTION: One of the underlying causes of recurrent pneumonia in children is swallowing dysfunction, with aspiration syndrome. Swallowing dysfunction should be considered not only a problem of the oropharyngeal phase but also a problem of the esophageal phase. OBJECTIVES: This study aimed to determine the relationship between findings from a swallowing study and a history of recurrent pneumonia in pediatric patients. METHODS: A videofluroscopic swallowing study of 274 pediatric patients who had swallowing dysfunction was conducted...
December 7, 2016: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27925172/effect-of-early-intervention-in-infants-at-very-high-risk-of-cerebral-palsy-a-systematic-review
#8
REVIEW
Mijna Hadders-Algra, Anke G Boxum, Tjitske Hielkema, Elisa G Hamer
AIM: First, to systematically review the evidence on the effect of intervention applied during the first postnatal year in infants with or at very high risk of cerebral palsy (CP) on child and family outcome. Second, to assess whether type and dosing of intervention modify the effect of intervention. METHOD: Relevant literature was identified by searching the PubMed, Embase, and CINAHL databases. Selection criteria included infants younger than 12 months corrected age with or at very high risk of CP...
December 7, 2016: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/27922865/additional-value-of-early-phase-18f-fp-cit-pet-image-for-differential-diagnosis-of-atypical-parkinsonism
#9
Soyoung Jin, Minyoung Oh, Seung Jun Oh, Jungsu S Oh, Sang Ju Lee, Sun Ju Chung, Jae Seung Kim
PURPOSE: Regional cerebral perfusion is coupled to metabolism in general. Early perfusion dominant imaging using F-FP-CIT PET (pCIT) may provide complementary information to delayed dopamine transporter dominant images. We investigated the ability of pCIT to differentiate atypical Parkinson disorder from Parkinson disease (PD) compared to FDG and the image quality for optimizing the acquisition time. METHODS: Sixty-seven subjects [PD, 23 subjects; multiple system atrophy-cerebellar type (MSA-C), 27 subjects; MSA-Parkinson type (MSA-P), 12 subjects; and progressive supranuclear palsy (PSP), 5 subjects] underwent F-FP-CIT and FDG PET...
December 3, 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27921445/risk-of-neonatal-and-childhood-morbidity-among-preterm-infants-exposed-to-marijuana
#10
Sarah K Dotters-Katz, Marcela C Smid, Tracy A Manuck, Torri D Metz
BACKGROUND: Limited data exist regarding the neonatal and neurodevelopmental outcomes of infants exposed to marijuana (MJ) in-utero, particularly among preterm infants. We hypothesized that MJ-exposed preterm infants would have worse neonatal and childhood developmental outcomes compared to MJ-unexposed infants. METHODS: Secondary analysis of multicenter randomized-controlled trial of antenatal magnesium sulfate for prevention of cerebral palsy was conducted. Singleton non-anomalous infants delivered <35 weeks exposed to MJ in-utero were compared to MJ-unexposed...
December 6, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27919794/diagnostic-utility-of-contrast-enhanced-3d-t1-weighted-imaging-in-acute-cerebral-infarction-associated-with-graves-disease
#11
Yasufumi Gon, Manabu Sakaguchi, Naoki Oyama, Hideki Mochizuki
Graves disease is rarely complicated with cerebrovascular steno-occlusive diseases. Previous studies have suggested several hypotheses for this occurrence, including excess thyroid hormone, which stimulates the sympathetic nervous system, which in turn causes an abnormal hemodynamic response with consequent atherosclerotic changes, and antithyroid antibodies cause local vascular inflammation in patients with Graves disease. However, radiological findings of vasculitis in patients with Graves disease and cerebral infarction remain less known...
December 2, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27917466/international-conference-on-cerebral-palsy-and-other-childhood-onset-disabilities-joint-meeting-of-28th-annual-meeting-of-the-european-academy-of-childhood-disability-eacd-5th-international-conference-of-cerebral-palsy-icpc-and-1st-meeting-of-the-international
#12
https://www.readbyqxmd.com/read/27916232/neuroinflammation-in-intrauterine-growth-restriction
#13
REVIEW
Julie A Wixey, Kirat K Chand, Paul B Colditz, S Tracey Bjorkman
Disruption to the maternal environment during pregnancy from events such as hypoxia, stress, toxins, inflammation, and reduced placental blood flow can affect fetal development. Intrauterine growth restriction (IUGR) is commonly caused by chronic placental insufficiency, interrupting supply of oxygen and nutrients to the fetus resulting in abnormal fetal growth. IUGR is a major cause of perinatal morbidity and mortality, occurring in approximately 5-10% of pregnancies. The fetal brain is particularly vulnerable in IUGR and there is an increased risk of long-term neurological disorders including cerebral palsy, epilepsy, learning difficulties, behavioural difficulties and psychiatric diagnoses...
November 25, 2016: Placenta
https://www.readbyqxmd.com/read/27912105/pre-operative-walking-activity-in-youth-with-cerebral-palsy
#14
Kristen Nicholson, Nancy Lennon, Robert Hulbert, Chris Church, Freeman Miller
BACKGROUND: No data are available regarding level of walking activity for youth with cerebral palsy (CP) before undergoing orthopeadic surgery. The goals of this study were to quantify pre-operative walking activity, and determine whether pre-operative values are different from previously defined levels of walking activity in youth with CP. PROCEDURES: This study retrospectively evaluated pre-operative walking activity in youth with spastic CP, GMFCS levels I-IV...
November 29, 2016: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/27912104/structured-skill-practice-during-intensive-bimanual-training-leads-to-better-trunk-and-arm-control-than-unstructured-practice-in-children-with-unilateral-spastic-cerebral-palsy
#15
Ya-Ching Hung, Marina B Brandão, Andrew M Gordon
BACKGROUND: Recently, intensive practice showed good efficacy in improving upper extremity function for children with unilateral spastic cerebral palsy (USCP). However, little is known about the significance of skill progression frequently used during intensive practice. AIMS: We evaluate the importance of skill progression during intensive bimanual practice on movement coordination. METHODS AND PROCEDURES: Twenty children with USCP (average age: 8...
November 29, 2016: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/27909356/effects-of-three-weeks-of-whole-body-vibration-training-on-joint-position-sense-balance-and-gait-in-children-with-cerebral-palsy-a-randomized-controlled-study
#16
Myung-Sook Ko, Yon Ju Sim, Do Hyun Kim, Hye-Seon Jeon
Purpose : To observe the effects of whole-body vibration (WBV) training in conjunction with conventional physical therapy (PT) on joint-position sense (JPS), balance, and gait in children with cerebral palsy (CP). Methods: In this randomized controlled study, 24 children with CP were randomly selected either to continue their conventional PT or to receive WBV in conjunction with their conventional PT programme. Exposure to the intervention was intermittent (3 min WBV, 3 min rest) for 20 minutes, twice weekly for 3 weeks...
2016: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/27908902/electronic-fetal-monitoring-cerebral-palsy-and-caesarean-section-assumptions-versus-evidence
#17
Karin B Nelson, Thomas P Sartwelle, Dwight J Rouse
No abstract text is available yet for this article.
December 1, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27907872/does-unilateral-single-event-multilevel-surgery-improve-gait-in-children-with-spastic-hemiplegia-a-retrospective-analysis-of-a-long-term-follow-up
#18
Christian Schranz, Annika Kruse, Tanja Kraus, Gerhardt Steinwender, Martin Svehlik
Single event multilevel surgery (SEMLS) has become a standard intervention for children with cerebral palsy (CP). SEMLS proved to improve the gait in bilateral spastic cerebral palsy and those improvements can be maintained in the long term. However there is no evidence on the long-term outcome of unilateral SEMLS in children with unilateral spastic cerebral palsy. The gait analyses and clinical data of 14 children (9 male/5 female, mean age 12.1) with unilateral CP (6 children Gross Motor Function Classification System Scale level I and 8 children level II) were retrospectively reviewed at four time-points: preoperatively, 1year, 3-5 years and approximately 10 years after unilateral SEMLS...
November 15, 2016: Gait & Posture
https://www.readbyqxmd.com/read/27906083/neonatal-diffusion-tensor-brain-imaging-predicts-later-motor-outcome-in-preterm-neonates-with-white-matter-abnormalities
#19
Do-Yeon Kim, Hyun-Kyung Park, Nam-Su Kim, Se-Jin Hwang, Hyun Ju Lee
BACKGROUND: White matter (WM) abnormalities associated with prematurity are one of the most important causes of neurological disability that involves spastic motor deficits in preterm newborns. This study aimed to evaluate regional microstructural changes in diffusion tensor imaging (DTI) associated with WM abnormalities. METHODS: We prospectively studied extremely low birth weight (ELBW; <1000 g) preterm infants who were admitted to the Neonatal Intensive Care Unit of Hanyang University Hospital between February 2011 and February 2014...
December 1, 2016: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/27904971/mutations-in-slc5a6-associated-with-brain-immune-bone-and-intestinal-dysfunction-in-a-young-child
#20
Veedamali S Subramanian, Alexandru R Constantinescu, Paul J Benke, Hamid M Said
The human sodium-dependent multivitamin transporter (hSMVT) is a product of the SLC5A6 gene and mediates biotin, pantothenic acid, and lipoate uptake in a variety of cellular systems. We report here the identification of mutations R94X, a premature termination, and R123L, a dysfunctional amino acid change, both in exon 3 of the SLC5A6 gene in a child using whole genome-scanning. At 15 months of age, the child showed failure to thrive, microcephaly and brain changes on MRI, cerebral palsy and developmental delay, variable immunodeficiency, and severe gastro-esophageal reflux requiring a gastrostomy tube/fundoplication, osteoporosis, and pathologic bone fractures...
November 30, 2016: Human Genetics
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