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Cerebral palsy

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https://www.readbyqxmd.com/read/28731515/analysis-of-structure-function-network-decoupling-in-the-brain-systems-of-spastic-diplegic-cerebral-palsy
#1
Dongha Lee, Chongwon Pae, Jong Doo Lee, Eun Sook Park, Sung-Rae Cho, Min-Hee Um, Seung-Koo Lee, Maeng-Keun Oh, Hae-Jeong Park
Manifestation of the functionalities from the structural brain network is becoming increasingly important to understand a brain disease. With the aim of investigating the differential structure-function couplings according to network systems, we investigated the structural and functional brain networks of patients with spastic diplegic cerebral palsy with periventricular leukomalacia compared to healthy controls. The structural and functional networks of the whole brain and motor system, constructed using deterministic and probabilistic tractography of diffusion tensor magnetic resonance images and Pearson and partial correlation analyses of resting-state functional magnetic resonance images, showed differential embedding of functional networks in the structural networks in patients...
July 21, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28730065/exploring-structural-violence-in-the-context-of-disability-and-poverty-in-zimbabwe
#2
Jennifer T Muderedzi, Arne H Eide, Stine H Braathen, Babill Stray-Pedersen
BACKGROUND: While it is widely assumed that disability, poverty and health are closely linked, research falls short of fully understanding the link. One approach to analysing the links between disability and poverty is through the concept of structural violence, referring to social structures that contribute to the impoverishment of individuals or communities. These structures can be political, ecological, legal and economic, among others. OBJECTIVE: To explore structural violence and how it affects families of children with cerebral palsy among the Tonga ethnic group living in poor rural communities of Binga in Zimbabwe...
2017: Afr J Disabil
https://www.readbyqxmd.com/read/28729059/ultrasonographic-assessment-of-femoral-cartilage-thickness-in-patients-with-cerebral-palsy
#3
Emre Adigüzel, Fatih Tok, Emre Ata, Evren Yaşar, Bilge Yilmaz
BACKGROUND: Cerebral palsy (CP) is one of the most disabling syndromes of children. To our knowledge, there has not yet been any reported evaluation of the effect of CP on distal femoral cartilage by ultrasonography. The value of understanding this effect on cartilage is that sonographic evaluation of cartilage thickness may help physician to predict the joint health of these children. OBJECTIVE: To determine whether femoral cartilage thickness in patients with CP is different from that of healthy control subjects...
July 17, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28728959/mechanisms-contributing-to-gait-speed-and-metabolic-cost-in-children-with-unilateral-cerebral-palsy
#4
Tatiana Pessoa Silva Pinto, Sérgio Teixeira Fonseca, Rejane Vale Gonçalves, Thales Rezende Souza, Daniela Virgínia Vaz, Paula Lanna Pereira Silva, Marisa Cotta Mancini
BACKGROUND: Gait speed and metabolic cost are indicators of functional capacity in children with cerebral palsy. Uncovering their mechanisms helps guide therapeutic actions. OBJECTIVES: To investigate the contributions of energy-generating and energy-conserving mechanisms to gait speed and metabolic cost of children with unilateral cerebral palsy. METHODS: Data on eccentric and concentric muscle work, co-contraction, elastic torque and vertical stiffness of the affected-limb, forcing torque of the non-affected limb, gait speed and metabolic cost were collected from 14 children with unilateral cerebral palsy, aged 6-12 years...
July 5, 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28728014/the-structured-observation-of-motor-performance-in-infants-can-detect-cerebral-palsy-early-in-neonatal-intensive-care-recipients
#5
Cecilia Montgomery, Kine Johansen, Steven Lucas, Bo Strömberg, Kristina Persson
BACKGROUND: The detection of motor problems in infancy requires a detailed assessment method that measures both the infants' level of motor development and movement quality. AIMS: To evaluate the ability of the Structured Observation of Motor Performance in Infants (SOMP-I) to detect cerebral palsy (CP) in neonatal intensive care recipients. STUDY DESIGN: Prospective cohort study analyzed retrospectively. SUBJECTS: 212 (girls: 96) neonatal intensive care recipients (mean gestational age 34weeks, range: 23-43)...
July 17, 2017: Early Human Development
https://www.readbyqxmd.com/read/28726663/-peculiarities-of-community-acquired-pneumonia-in-children-with-neurological-pathology
#6
O Zubarenko, G Kopiyka, T Kravchenko, L Koval, K Gurienko
Neurological disorders in children highly affect the course of pneumonia, its outcome and the development of possible complications. The aim of the study was to reveal clinical and paraclinical features of community-acquired pneumonia in younger children with neurologic pathology infantile cerebral palsy. Under observation were 37 children with community-acquired pneumonia aged 1 to 3 years that suffered from spastic forms of infantile cerebral palsy. The comparison group consisted of 30 children with community-acquired pneumonia without any concomitant neurological pathology...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726270/equimolar-mixture-of-nitroux-oxyde-and-oxygen-during-post-operative-physiotherapy-in-patients-with-cerebral-palsy-a-randomized-double-blind-placebo-controlled-study
#7
A Delafontaine, A Presedo, D Mohamed, D Lopes, C Wood, C Alberti
BACKGROUND: The administration of an equimolar mixture of nitrous oxide and oxygen (N2O) is recommended during painful procedures. However, the evaluation of its use during physiotherapy after surgery has not been reported, although pain may hamper physiotherapy efficiency. This study investigated whether the use of N2O improves the efficacy of post-operative physiotherapy after multilevel surgery in patients with cerebral palsy. METHOD: It was a randomized 1:1, double-blind, placebo-controlled study...
July 20, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28726079/bilirubin-enzyme-biosensor-potentiality-and-recent-advances-towards-clinical-bioanalysis
#8
REVIEW
Vinita Hooda, Anjum Gahlaut, Ashish Gothwal, Vikas Hooda
Bilirubin detection plays a major role in healthcare. Its high concentration in human serum is lethal and must be determined accurately. Clinically, it is vital for assessing patients with deleterious health conditions such as jaundice or icterus, hepatitis, mental disorders, cerebral palsy and brain damage especially in the case of neonates. In evaluating the drawbacks regarding the conventional methodology of bilirubin detection, there is need for a superior analytical tool. Bilirubin oxidase (BOx)-based sensors have been designed for the ultrasensitive analysis of bilirubin and quality deliverance of treatment and this review highlights the different mechanisms of bilirubin detection using different modified electrodes...
July 19, 2017: Biotechnology Letters
https://www.readbyqxmd.com/read/28724781/muscle-disuse-caused-by-botulinum-toxin-injection-leads-to-increased-central-gain-of-the-stretch-reflex-in-the-rat
#9
Jessica Pingel, Hans Hultborn, Lui Naslund-Koch, Dennis Bo Jensen, Jacob Wienecke, Jens Bo Nielsen
Botulinum toxin (Btx) is used in children with cerebral palsy and other neurological patients to diminish spasticity and reduce the risk of development of contractures. Here, we investigated changes in the central gain of the stretch reflex circuitry in response to botulinum toxin injection in the triceps surae muscle in rats. Experiments were performed in 21 rats. 8 rats were in a control group and 13 rats were injected with 6 IU of Btx in the left triceps surae muscle. Two weeks after Btx injection larger monosynaptic reflexes (MSR) were recorded from the left (injected) than the right (non-injected) L4 + L5 ventral roots following stimulation of the corresponding dorsal roots...
July 19, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28723982/assessment-of-nutritional-status-of-children-and-adolescents-with-spastic-quadriplegic-cerebral-palsy
#10
Thaisa Barboza Caselli, Elizete Aparecida Lomazi, Maria Augusta Santos Montenegro, Maria Angela Bellomo-Brandão
BACKGROUND: Due to several factors, such as gastrointestinal's diseases and difficulty in feeding, children with Spastic Quadriplegic Cerebral Palsy tend to present nutritional deficits. OBJECTIVE: To assess the nutritional status of pediatric patients with Spastic Quadriplegic Cerebral Palsy according to reference curves for this population and with the measures of folds and circumferences, obtained by the upper arm circumference and triceps skin fold. METHODS: The data were obtained from: knee-height, estimated height, weight, upper arm circumference, and triceps skin fold...
July 6, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28720746/-a-rare-case-of-ruptured-internal-carotid-posterior-communicating-artery-aneurysm-associated-with-contralateral-delayed-oculomotor-nerve-palsy
#11
Chika Somagawa, Yutaka Fukuda, Shota Yoshimura, Kei Satoh, Takeshi Hiu, Tomonori Ono, Ryujirou Ushijima, Keisuke Toda, Keisuke Tsutsumi
A 55-year-old man presented with difficulty breathing, chest pain, and disturbance of consciousness, and was transferred to our hospital. Initial whole body CT revealed a diffuse subarachnoid hemorrhage(SAH)with severe pulmonary edema that was considered neurogenic in origin. He received controlled ventilation under sedation and conservative care for the SAH. One day after the onset of the SAH, his left pupil suddenly became dilated to 6mm, with no reaction to light. Head CT showed no new bleeding. Subsequent CT angiogram revealed a right internal carotid-posterior communicating artery aneurysm(IC-PC AN)with a posterior-lateral projection; however, no vessel abnormality was observed in the left anterior or posterior circulations...
July 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28720597/accuracy-of-administrative-claims-data-for-cerebral-palsy-diagnosis-a-retrospective-cohort-study
#12
Maryam Oskoui, Pamela Ng, Marc Dorais, Nicole Pigeon, Louise Koclas, Céline Lamarre, Francine Malouin, Carol L Richards, Michael Shevell, Lawrence Joseph
BACKGROUND: Cerebral palsy is the most common cause of childhood physical disability, with multiple associated comorbidities. Administrative claims data provide population-level prevalence estimates for cerebral palsy surveillance; however, their diagnostic accuracy has never been validated in Quebec. This study aimed to assess the accuracy of administrative claims data for the diagnosis of cerebral palsy. METHODS: We conducted a retrospective cohort study of children with cerebral palsy born between 1999 and 2002 within 6 health administrative regions of Quebec...
July 18, 2017: CMAJ Open
https://www.readbyqxmd.com/read/28720522/patients-with-non-ambulatory-cerebral-palsy-have-higher-sclerostin-levels-and-lower-bone-mineral-density-than-patients-with-ambulatory-cerebral-palsy
#13
Yoon-Kyum Shin, Young Kwon Yoon, Kyung Bae Chung, Yumie Rhee, Sung-Rae Cho
Bone loss is a serious clinical issue in patients with cerebral palsy (CP). Sclerostin has garnered interest as a key mechanosensor in osteocytes, leading to considerations of the therapeutic utilization of anti-sclerostin medications. This study was undertaken to determine associations among mechanical unloading, sclerostin levels, and bone imbalance in patients with CP. A total of 28 patients with CP participated in this cross-sectional study. The following measurements were taken: anthropometrics, clinical diagnosis of CP subtype and ambulatory status, bone mineral density (BMD) z-scores at the lumbar spine and hip, and blood biochemical markers, including sclerostin, parathyroid hormone (PTH), osteocalcin, C-terminal telopeptide, 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D, creatinine, calcium, and phosphorus...
July 15, 2017: Bone
https://www.readbyqxmd.com/read/28720233/the-effect-of-reflexology-upon-spasticity-and-function-among-children-with-cerebral-palsy-who-received-physiotherapy-three-group-randomised-trial
#14
Filiz Özkan, Handan Zincir
PURPOSE: To assess the effectiveness of reflexology method upon spasticity and function among children with cerebral palsy who received physiotherapy. METHODS: A three group, randomised trial with blinded evaluator. Randomization was made sealed and opaque envelopes. 45 children with cerebral palsy who were trained at a Special Education and Rehabilitation Centre. In the reflexology and placebo group; a 20min reflexology was performed twice a week in a total 24 sessions...
August 2017: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/28716693/the-effects-of-reflexology-on-constipation-and-motor-functions-in-children-with-cerebral-palsy
#15
Bulent Elbasan, Sabiha Bezgin
BACKGROUND: There is no evidence regarding the effects of reflexology on constipation and motor functions in children with cerebral palsy. This study was planned to investigate the effects of reflexology combined with neurodevelopmental therapy on constipation and motor functions in children with cerebral palsy. METHODS: Forty children between the ages of 3 and 15 years with cerebral palsy within levels 3/4/5 according to the Gross Motor Function Classification System (GMFCS) were included in the study...
June 29, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/28716514/toe-walking-when-do-we-need-to-worry
#16
Olga M Morozova, Thomas F Chang, Mackenzie E Brown
Toe walking refers to the lack of heel strike during the stance phase of the gait cycle. It is a common variation of normal gait development in children. Persistent toe walking past 2-3 years of age warrants further evaluation as toe walking can be associated with cerebral palsy, muscular dystrophy, and autism spectrum disorders. The diagnosis of idiopathic toe walking is a diagnosis of exclusion used for children with persistent toe walking and no associated medical condition. Despite variable pathophysiology, the treatment of toe walking has similarities across diagnoses as it is focused on the maintenance of range of motion through the ankle...
July 14, 2017: Current Problems in Pediatric and Adolescent Health Care
https://www.readbyqxmd.com/read/28715518/early-accurate-diagnosis-and-early-intervention-in-cerebral-palsy-advances-in-diagnosis-and-treatment
#17
Iona Novak, Cathy Morgan, Lars Adde, James Blackman, Roslyn N Boyd, Janice Brunstrom-Hernandez, Giovanni Cioni, Diane Damiano, Johanna Darrah, Ann-Christin Eliasson, Linda S de Vries, Christa Einspieler, Michael Fahey, Darcy Fehlings, Donna M Ferriero, Linda Fetters, Simona Fiori, Hans Forssberg, Andrew M Gordon, Susan Greaves, Andrea Guzzetta, Mijna Hadders-Algra, Regina Harbourne, Angelina Kakooza-Mwesige, Petra Karlsson, Lena Krumlinde-Sundholm, Beatrice Latal, Alison Loughran-Fowlds, Nathalie Maitre, Sarah McIntyre, Garey Noritz, Lindsay Pennington, Domenico M Romeo, Roberta Shepherd, Alicia J Spittle, Marelle Thornton, Jane Valentine, Karen Walker, Robert White, Nadia Badawi
Importance: Cerebral palsy describes the most common physical disability in childhood and occurs in 1 in 500 live births. Historically, the diagnosis has been made between age 12 and 24 months but now can be made before 6 months' corrected age. Objectives: To systematically review best available evidence for early, accurate diagnosis of cerebral palsy and to summarize best available evidence about cerebral palsy-specific early intervention that should follow early diagnosis to optimize neuroplasticity and function...
July 17, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28714530/acoustic-changes-in-the-speech-of-children-with-cerebral-palsy-following-an-intensive-program-of-dysarthria-therapy
#18
Lindsay Pennington, Eftychia Lombardo, Nick Steen, Nick Miller
BACKGROUND: The speech intelligibility of children with dysarthria and cerebral palsy has been observed to increase following therapy focusing on respiration and phonation. AIMS: To determine if speech intelligibility change following intervention is associated with change in acoustic measures of voice. METHODS & PROCEDURES: We recorded 16 young people with cerebral palsy and dysarthria (nine girls; mean age 14 years, SD = 2; nine spastic type, two dyskinetic, four mixed; one Worster-Drought) producing speech in two conditions (single words, connected speech) twice before and twice after therapy focusing on respiration, phonation and rate...
July 17, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/28714339/inhaled-and-systemic-steroid-exposure-and-neurodevelopmental-outcome-of-preterm-neonates
#19
Edmond N Kelly, Vibhuti S Shah, Jody Levenbach, Michael Vincer, Orlando DaSilva, Prakesh S Shah
OBJECTIVES: To compare death and/or neurodevelopmental outcomes of preterm infants exposed to inhaled and/or systemic steroids with those without exposure, and examine the impact of timing of exposure. METHODS: Retrospective study of infants born <29 weeks gestation and assessed at 18-21 months corrected age (CA). Neurodevelopmental impairment (NDI) was defined as any Bayley Scales of Infant and Toddler Development-III (BSID-III) score <85, cerebral palsy ≥ grade one, and visual or hearing impairment...
July 16, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28713039/efficacy-of-ankle-foot-orthoses-types-on-walking-in-children-with-cerebral-palsy-a-systematic-review
#20
REVIEW
Atefeh Aboutorabi, Mokhtar Arazpour, Monireh Ahmadi Bani, Hassan Saeedi, John S Head
BACKGROUND: Ankle foot orthoses (AFOs) are orthotic devices that can be used to normalize the walking pattern of children with cerebral palsy (CP). One of the aims of orthotic management is to produce a more normal gait pattern by positioning joints in the proper position to reduce pathological reflex or spasticity. OBJECTIVE: To conduct a systematic review of the literature and establish the effect of treatment with various types of AFOs on gait patterns of children with CP...
July 13, 2017: Annals of Physical and Rehabilitation Medicine
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