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Cerebral palsy

Anne Eskild, Lars Monkerud, Anne Marie Jukic, Bjørn Olav Åsvold, Kari Kveim Lie
BACKGROUND: Intrauterine conditions may be important in the development of cerebral palsy in the child. The hormone, human chorionic gonadotropin (hCG), is synthesized in the placenta, and hCG plays an important role in placental angiogenesis and development. Thus, maternal hCG concentrations may be an indicator of placental function and thereby the intrauterine environment for the offspring. We studied the associations of maternal concentrations of hCG during pregnancy with cerebral palsy in the child...
July 4, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
María B Sánchez, Ian Loram, Paul Holmes, John Darby, Penelope B Butler
BACKGROUND: Physical therapy evaluations of motor control are currently based on subjective clinical assessments. Despite validation, these can still be inconsistent between therapists and between clinics, compromising the process of validating a therapeutic intervention and the subsequent generation of evidence-based practice (EBP) guidelines. EBP benefits from well-defined objective measurements that complement existing subjective assessments. RESEARCH QUESTION: The aim of this study was to develop an objective measure of head/trunk control in children with Cerebral Palsy (CP) using previously developed video-based methods of head/trunk alignment and absence of external support and compare these with the existing subjective Segmental Assessment of Trunk Control (SATCo)...
June 30, 2018: Gait & Posture
Nona M Jiang, Maureen Cowan, Shannon N Moonah, William A Petri
Inflammatory mediators affect the brain during development. Neurodevelopmental disorders such as autism spectrum disorders, cognitive impairment, cerebral palsy, epilepsy, and schizophrenia have been linked to early life inflammation. Recent advances have shown the effects of systemic inflammation on children's neurodevelopment. We discuss the potential mechanisms by which inflammatory molecules can exert their effects on the developing brain and consider the roles of MHC class I molecules, the HPA axis, glial cells, and monoamine metabolism...
July 10, 2018: Trends in Molecular Medicine
A Salehi, A Khandan, M Arab Baniasad, S Baghdadi, F Farahmand, H Zohoor
No abstract text is available yet for this article.
July 3, 2018: Gait & Posture
Y Gagnat, S M Brændvik, K Roeleveld
In children with CP excessive co-activation is often reported. This abstract aimed to compare two indices for co-activation quantification and evaluated the relationship between co-activation and gait velocity and step length. Twelve children with CP and seven TD walked with sEMG measurements from lower limb muscles. Co-activation was calculated during 50-80% of stance phase. Level of co-activation was higher in CP than TD and there were differences between the two indices. There was no relationship between co-activation and gait velocity or step length...
July 2, 2018: Gait & Posture
Christopher J Newman
No abstract text is available yet for this article.
July 11, 2018: Developmental Medicine and Child Neurology
(no author information available yet)
No abstract text is available yet for this article.
July 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
Christian-Dominik Peterlein, Sinja Friedrich, Hanna Daniel, Dominik Malcherczyk, Janine Ruden, Bilal F El Zayat
BACKGROUND: There have been few publications on the organisational structures of self-help groups that handle orthopaedic disorders in children. MATERIAL AND METHODS: A standardised questionnaire was sent by post to the corresponding support groups. The aim was to evaluate the self-help group's structure, use of social media and financial background. RESULTS: Support groups for dwarfism, infantile cerebral palsy and Down syndrome responded and sent the questionnaire back to our department...
July 11, 2018: Zeitschrift Für Orthopädie und Unfallchirurgie
(no author information available yet)
No abstract text is available yet for this article.
August 2018: Journal of Pediatric Orthopedics
Jesús David Charry-Sánchez, Iván Pradilla, Claudia Talero-Gutiérrez
OBJECTIVE: To synthesize the results of controlled studies evaluating the effectiveness of animal-assisted therapy (AAT) in children. METHODS: Eleven databases were searched following the Preferred Reporting Items for Systematic Reviews and Meta-analyses statement recommendations, and references from included studies and previous reviews were examined. No date or language filters were applied. Only controlled study designs, including those using wait-list controls, that studied a specific condition or illness were included...
July 6, 2018: Journal of Developmental and Behavioral Pediatrics: JDBP
Katlyn Scarpinella
No abstract text is available yet for this article.
July 9, 2018: American Journal of Physical Medicine & Rehabilitation
Edward Washabaugh, Jane Guo, Chih-Kang Chang, David Remy, Chandramouli Krishnan
OBJECTIVE: Loss of arm function is common in individuals with neurological damage, such as stroke or cerebral palsy. Robotic devices that address muscle strength deficits in a task-specific manner can assist in the recovery of arm function; however, current devices are typically large, bulky, and expensive to be routinely used in the clinic or at home. This study sought to address this issue by developing a portable planar passive rehabilitation robot, PaRRo. METHODS: We designed PaRRo with a mechanical layout that incorporated kinematic redundancies to generate forces that directly oppose the user's movement...
June 21, 2018: IEEE Transactions on Bio-medical Engineering
Saviour Kweku Adjenti, Graham Jacob Louw, Jennifer Jelsma, Marianne Unger
Background: Abdominal muscles have stiffer appearance in individuals with spastic type cerebral palsy (STCP) than in their typically developing (TD) peers. This apparent stiffness has been implicated in pelvic instability, mal-rotation, poor gait and locomotion. This study was aimed at investigating whether abdominal muscles activation patterns from rest to activity differ in the two groups. Method: From ultrasound images, abdominal muscles thickness during the resting and active stages was measured in 63 STCP and 82 TD children...
2018: Archives of Physiotherapy
Jaechun Hwang, Mi Ji Lee, Jong-Won Chung, Oh Young Bang, Gyeong-Moon Kim, Chin-Sang Chung, Kwang Ho Lee
Background and purpose The status of collateral vessels has important clinical implications in acute ischemic stroke. To evaluate which components of ischemic symptoms were predictive of pretreatment collateral status, we tested the hypothesis that sub-item scores from the National Institutes of Health Stroke Scale (NIHSS) are associated with leptomeningeal collateral status in acute ischemic stroke with middle cerebral artery (MCA) occlusion. Methods This study included consecutive patients with acute M1 occlusion who underwent revascularization treatment for acute MCA infarction...
January 1, 2018: Interventional Neuroradiology
Do Hyun Kim, Duk-Hyun An, Won-Gyu Yoo
BACKGROUND: Poor postural control constitutes a major impairment in children with cerebral palsy (CP), compromising everyday activities such as sitting- and standing-position. PURPOSE: In this study, we measured trunk sway during sitting- and standing-position. Additionally, we assessed trunk control ability using the trunk impairment scale (TIS), trunk control measurement scale (TCMS), and sitting assessment test for children with neuromotor dysfunction (SACND), in children with CP...
June 29, 2018: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
Sabrina Yu, Helen L Carlson, Aleksandra Mineyko, Brian L Brooks, Andrea Kuczynski, Jacquie Hodge, Sean Dukelow, Adam Kirton
Background: Stroke is a leading cause of perinatal brain injury with variable outcomes including cerebral palsy and epilepsy. The biological processes that underlie these heterogeneous outcomes are poorly understood. Alterations in developmental myelination are recognized as a major determinant of outcome in preterm brain injury but have not been explored in perinatal stroke. We aimed to characterize myelination in hemiparetic children after arterial perinatal stroke, hypothesizing that ipsilesional myelination would be impaired, the degree of which would correlate with poor outcome...
2018: NeuroImage: Clinical
Andrea Morris, Christine Imms, Claire Kerr, Brooke Adair
PURPOSE: Short-term physical activity programs may encourage adolescents with cerebral palsy to participate in physical activity but how to sustain their involvement is not well known. This qualitative study aimed to identify facilitators that successfully sustain physical activity participation by adolescents with cerebral palsy. MATERIALS AND METHODS: Adolescents (12-18 years) with cerebral palsy [Gross Motor Function Classification System (GMFCS) levels I-V, without moderate-severe intellectual disability] who participated in regular physical activity were eligible, as well as one parent and an individual who facilitated their physical activity...
July 10, 2018: Disability and Rehabilitation
Amir Eftekhar, James J S Norton, Christine M McDonough, Jonathan R Wolpaw
Neurological disorders, such as spinal cord injury, stroke, traumatic brain injury, cerebral palsy, and multiple sclerosis cause motor impairments that are a huge burden at the individual, family, and societal levels. Spinal reflex abnormalities contribute to these impairments. Spinal reflex measurements play important roles in characterizing and monitoring neurological disorders and their associated motor impairments, such as spasticity, which affects nearly half of those with neurological disorders. Spinal reflexes can also serve as therapeutic targets themselves...
July 9, 2018: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
Brunno L Moreira, Tasos Karakostas, Luciano S Dias
BACKGROUND: Rectus femoris transfer (RFT) is performed in children with cerebral palsy to treat stiff-knee gait. However, the results are variable in part because there is no gold standard to identify appropriate candidates. Hip flexion kinematics and kinetics are important factors in the determination of peak knee flexion during gait. This study aimed to evaluate whether a kinetic preoperative analysis of hip power can be a predictor of RFT outcomes and determine its usability for identifying appropriate candidates for the procedure...
July 6, 2018: Journal of Pediatric Orthopedics
Ilaria Bortone, Daniele Leonardis, Nicola Mastronicola, Alessandra Crecchi, Luca Bonfiglio, Caterina Procopio, Massimiliano Solazzi, Antonio Frisoli
The past decade has seen the emergence of rehabilitation treatments using virtual reality (VR) environments although translation into clinical practice has been limited so far. In this paper, an immersive VR rehabilitation training system endowed with wearable haptics is proposed for children with neuromotor impairments: it aims to enhance involvement and engagement of patients, to provide congruent multi-sensory afferent feedback during motor exercises and to benefit from the flexibility of VR in adapting exercises to the patient's need...
July 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
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