Lorenzo Bianco, Alessandro Arrigo, Alessio Antropoli, Sebastiano Del Fabbro, Paola Panina-Bordignon, Carolina Peri, Elena Brambilla, Adelaide Pina, Giulia Basile, Rashid Hassan Farah, Andrea Saladino, Emanuela Aragona, Maria Lucia Cascavilla, Francesco Bandello, Maurizio Battaglia Parodi, Jose S Pulido
PURPOSE: To determine if circulating antiretinal antibodies (ARAs) differ between patients affected by retinitis pigmentosa (RP) and control participants and to assess whether ARAs are associated with clinical outcomes in patients with RP. METHODS: Cross-sectional study involving a group of patients clinically diagnosed with RP and a control group of healthy participants. Serum autoantibodies against enolase, heat shock protein 70 (HSP70), and carbonic anhydrase II (CAII) were tested in all participants using Jess capillary Western blot...
December 1, 2023: Investigative Ophthalmology & Visual Science