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https://www.readbyqxmd.com/read/29683306/maternity-care-update-prenatal-care-and-specific-conditions
#1
Andrew Smith, Wendy B Barr, Erin Bassett-Novoa, Nicholas LeFevre
Early initiation of prenatal care is associated with improved health outcomes for women and newborns. An essential element of prenatal care is determining the estimated due date, ideally using a first-trimester ultrasound. Laboratory tests should be obtained to screen for conditions that can affect pregnancy. Routine immunizations for all pregnant women include influenza vaccine; tetanus toxoid, reduced diphtheria, acellular pertussis (Tdap) vaccine. All women should be screened for gestational diabetes mellitus in midpregnancy...
April 2018: FP Essentials
https://www.readbyqxmd.com/read/29680828/viral-pneumonia-etiologies-and-treatment
#2
Dima Dandachi, Maria C Rodriguez-Barradas
Viral pathogens are increasingly recognized as a cause of pneumonia, in immunocompetent patients and more commonly among immunocompromised. Viral pneumonia in adults could present as community-acquired pneumonia (CAP), ranging from mild disease to severe disease requiring hospital admission and mechanical ventilation. Moreover, the role of viruses in hospital-acquired pneumonia and ventilator-associated pneumonia as causative agents or as co-pathogens and the effect of virus detection on clinical outcome are being investigated...
April 20, 2018: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
https://www.readbyqxmd.com/read/29680761/vitrified-medical-wastes-bottom-ash-in-cement-clinkerization-microstructural-hydration-and-leaching-characteristics
#3
S Papamarkou, D Christopoulos, P E Tsakiridis, G Bartzas, K Tsakalakis
The present investigation focuses on the utilization of medical wastes incineration bottom ash (MBA), vitrified with soda lime recycled glass (SLRG), as an alternative raw material in cement clinkerization. Bottom ash is recovered from the bottom of the medical wastes incineration chamber, after being cooled down through quenching. It corresponds to 10-15 wt% of the initial medical wastes weight and since it has been classified in the category of hazardous wastes, its safe management has become a major environmental concern worldwide...
April 19, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29678705/hypophysitis-due-to-paranasal-sinusitis-a-neurosurgical-perspective-from-the-developing-world
#4
El Faith Bashir El Malik, Branavan Manoranjan, Olufemi Ajani, Ahmed Zidan
BACKGROUND: and Importance: Sinusitis is a common clinical condition but sphenoid sinusitis is a less common form and even rarer is hypophysitis as a complication of the latter. Clinically, hypophysitis may mimic a pituitary neoplasm in presenting with mass effect and pituitary hormone dysfunction. CLINICAL PRESENTATION: We present five cases of sinusitis-related hypophysitis treated at the Royal Care International Hospital in Khartoum, Sudan. Clinical symptoms at presentation included: headache, fever, ptosis, ophthalmoplegia and history of sinusitis with running nose (nasal discharge)...
April 17, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29677968/risk-and-disaster-management-from-planning-and-expertise-to-smart-intelligent-and-adaptive-systems
#5
Arriel Benis, Amos Notea, Refael Barkan
"Disaster" means some surprising and misfortunate event. Its definition is broad and relates to complex environments. Medical Informatics approaches, methodologies and systems are used as a part of Disaster and Emergency Management systems. At the Holon Institute of Technology - HIT, Israel, in 2016 a National R&D Center: AFRAN was established to study the disaster's reduction aspects. The Center's designation is to investigate and produce new approaches, methodologies and to offer recommendations in the fields of disaster mitigation, preparedness, response and recovery and to disseminate disaster's knowledge...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29672125/submassive-pulmonary-embolism
#6
Parth M Rali, Gerard J Criner
Pulmonary Embolism (PE) presents a spectrum of hemodynamic consequences ranging from being asymptomatic to a life-threatening medical emergency. Management of sub massive and massive PE often involves clinicians from multiple specialties that can potentially delay the development of a unified treatment plan. Additionally, patients with submassive PE can deteriorate after their presentation and require escalation of care. Underlying comorbidities like chronic obstructive pulmonary disease (COPD), cancer, congestive heart failure and interstitial lung disease can impact the patient's hemodynamic ability to tolerate submassive PE...
April 19, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29670747/percutaneous-management-of-ostial-stenosis-of-the-left-internal-mammary-artery-graft
#7
Tanuka Datta, Mohammed Gibreal, Ramesh Mazhari, Allen J Solomon
A 61-year-old man, who had undergone coronary artery bypass surgery 10 years earlier, presented with a non-ST segment elevation myocardial infarction. He was treated with medical therapy and taken to the Cardiac Catheterization Laboratory. A left heart catheterization demonstrated an ostial stenosis in the left internal mammary artery graft, which was felt to be the culprit lesion. This was successfully repaired with a drug eluting stent. This case is presented as an unusual location for a de novo coronary stenosis...
January 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29669791/retrospective-evaluation-of-infants-aged-1-60-days-with-residual-csf-tested-using-the-filmarray%C3%A2-meningitis-encephalitis-me-panel
#8
Anne J Blaschke, Kristen M Holmberg, Judy A Daly, Amy L Leber, Jennifer Dien Bard, Ernest K Korgenski, Kevin M Bourzac, Kristen J Kanack
In pediatric practice it is common for infants under 2 months of age to undergo evaluation for sepsis when they are ill, often including lumbar puncture (LP) to assess for central nervous system (CNS) infection. The FilmArray® Meningitis/Encephalitis (ME) Panel is a newly approved test for rapid identification of CNS pathogens. Our objective was to study the epidemiology of CNS infection in young infants and the potential impact of rapid multiplex PCR on their care.A performance evaluation of the FilmArray ME Panel was conducted from 2/2014-9/2014 at 11 sites...
April 18, 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29669313/role-of-fna-and-special-stains-in-rapid-cytopathological-diagnosis-of-pulmonary-nocardiosis
#9
Ridhi Sood, Ruchita Tyagi, Pavneet Kaur Selhi, Gursheen Kaur, Harpreet Kaur, Akashdeep Singh
BACKGROUND: Nocardia, a gram-positive aerobic bacillus of the Actinomycetales family, is a significant opportunistic pathogen in immunocompromised individuals. Clinical and radiological features of pulmonary nocardiosis are nonspecific and can be misdiagnosed as tuberculosis, pneumocystis, staphylococcal or fungal infections, or as malignancy. Aspiration cytology with special stains is a quick and effective approach for accurate diagnosis. MATERIALS AND METHODS: We present 7 cases of pulmonary nocardiosis, admitted to the pathology department in a tertiary-care hospital in Punjab...
April 18, 2018: Acta Cytologica
https://www.readbyqxmd.com/read/29667798/delusional-infestation-in-psychodermatology
#10
Monica Rosales Santillan, Dustin L Taylor, Jason S Reichenberg
Delusional infestation (DI), also known as delusional parasitosis, consists of a patient's strong belief that he or she is infested with a nonliving substance or living organism despite lack of medical evidence to support this belief. The most commonly reported sources of infestation include insects, fibrous strands, worms, and scabies. Delusional infestation is predominantly seen in women and older patients. This disorder has a variable course and prognosis in patients. Delusional infestation can be a primary psychiatric problem, or secondary to underlying medical conditions or other psychiatric disorders...
April 18, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29664506/continuous-venovenous-hemofiltration-in-neonates-with-hyperammonemia-a-case-series
#11
Felipe Cavagnaro Santa María, Jorge Roque Espinosa, Pamela Guerra Hernández
INTRODUCTION: Neonatal hyperammonemia secondary due to inborn errors of metabolism is a rare condition with a high rate of neurological sequelae and mortality. Initial medical management is often insufficient to stop the progressive increase of ammonia, with the consequent deterioration of the patient. For this reason, depurative techniques have been implemented, including peritoneal dialysis, intermittent hemodialysis and continuous renal replacement therapy (CRRT). OBJECTIVE: To describe our experience with continuous extracorporeal dialysis in severely ill neonates with hyperammonemia...
February 2018: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/29663952/timing-of-hiv-diagnosis-in-children-with-tuberculosis-managed-at-a-referral-hospital-in-cape-town-south-africa
#12
L N Byamungu, K du Preez, E Walters, J B Nachega, H S Schaaf
SETTING: Tygerberg Hospital, Western Cape Province, Cape Town, South Africa. OBJECTIVE: To investigate the prevalence of and factors associated with simultaneous tuberculosis (TB) and human immunodeficiency virus (HIV) diagnoses in children. DESIGN: Retrospective cohort study in TB-HIV co-infected children aged <13 years admitted to Tygerberg Hospital in 2012. Data were collected from medical records, laboratory results and electronic TB treatment registers...
May 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29662732/institutional-review-of-hemorrhagic-pelvic-emergencies-effectively-managed-with-percutaneous-arterial-embolization
#13
Muhammad Azeemuddin, Raza Sayani, Nauman Turab, Syed M Mustahsan, Mohammad Hasan, Dawar B Khan, Fatima Mubarak
OBJECTIVE: Our aim was to review the results of pelvic arterial embolization (PAE) performed in the interventional radiology suite. METHOD: The data of all patients in whom pelvic angioembolization was performed was collected from July 2011 to June 2017. Procedures were performed by an experienced interventional radiologist. The clinical and laboratory data, as well as the outcome data, were obtained from the medical records of our hospital. The following parameters were collected for each patient, including the age, gender, presenting symptoms, site of bleeding, catheters used for embolization, material used for embolization, previous computed tomography (CT) scan and/or focused assessment with sonography for trauma (FAST) ultrasound, average hemoglobin before the procedure, and patient clinical status on discharge...
February 15, 2018: Curēus
https://www.readbyqxmd.com/read/29659675/facing-the-inevitable-being-prepared-for-regulatory-requirements-for-laboratory-developed-tests
#14
Rita D'Angelo, Ronald Weiss, David Wolfe, Ratna Chinnam, Alper Murat, Julia Gluesing, Toni Somers
Objectives: We introduce regulatory terms, definitions, and the Quality System Regulation as proposed by the US Food and Drug Administration in the 2014 draft guidance entitled Framework for Regulatory Oversight of Laboratory Developed Tests and explore medical device requirements applicable to a laboratory environment to design, develop, and validate laboratory developed tests (LDTs). Methods: We performed nine interviews with laboratory professionals to explore concerns and challenges regarding the draft, translated the results into operational factors, and surveyed professionals to test the factors that would comprise a regulatory quality management system framework...
April 5, 2018: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29658382/the-impact-of-digital-technologies-on-point-of-care-diagnostics-in-resource-limited-settings
#15
Natasha Gous, Debrah I Boeras, Ben Cheng, Jeff Takle, Brad Cunningham, Rosanna W Peeling
Simple, rapid tests that can be used at the point-of-care (POC) can improve access to diagnostic services and overall patient management in resource-limited settings where laboratory infrastructure is limited. Implementation of POC tests places tremendous strain on already fragile health systems as the demand for training, supply management and quality assurance are amplified. Digital health has a major role to play in ensuring effective delivery and management of POC testing services. Area covered: The ability to digitise laboratory and POC platforms, including lateral flow rapid diagnostic test results, can standardize the interpretation of results and allows data to be linked to proficiency testing to ensure testing quality, reducing interpretation and transcription errors...
April 2018: Expert Review of Molecular Diagnostics
https://www.readbyqxmd.com/read/29657312/left-upper-quadrant-appendicitis-in-a-patient-with-congenital-intestinal-malrotation-and-polysplenia
#16
Camille Lupiañez-Merly, Stephanie C Torres-Ayala, Lorena Morales, Adel Gonzalez, José A Lara-Del Rio, Ivonne Ojeda-Boscana
BACKGROUND Appendicitis is the most common cause of abdominal pain requiring emergent surgical intervention. Although typically presenting as right lower-quadrant pain, in rare cases it may present as left upper-quadrant pain secondary to abnormal position due to intestinal malrotation. Since atypical presentations may result in diagnostic and management delay, increasing morbidity and mortality, accurate and prompt diagnosis is important. Therefore, acute appendicitis should be considered in the differential diagnosis of left upper-quadrant abdominal pain...
April 16, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29653352/online-molecular-image-repository-and-analysis-system-a-multicenter-collaborative-open-source-infrastructure-for-molecular-imaging-research-and-application
#17
Mahabubur Rahman, Hiroshi Watabe
Molecular imaging serves as an important tool for researchers and clinicians to visualize and investigate complex biochemical phenomena using specialized instruments; these instruments are either used individually or in combination with targeted imaging agents to obtain images related to specific diseases with high sensitivity, specificity, and signal-to-noise ratios. However, molecular imaging, which is a multidisciplinary research field, faces several challenges, including the integration of imaging informatics with bioinformatics and medical informatics, requirement of reliable and robust image analysis algorithms, effective quality control of imaging facilities, and those related to individualized disease mapping, data sharing, software architecture, and knowledge management...
April 4, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29650709/machine-learning-methods-improve-prognostication-identify-clinically-distinct-phenotypes-and-detect-heterogeneity-in-response-to-therapy-in-a-large-cohort-of-heart-failure-patients
#18
Tariq Ahmad, Lars H Lund, Pooja Rao, Rohit Ghosh, Prashant Warier, Benjamin Vaccaro, Ulf Dahlström, Christopher M O'Connor, G Michael Felker, Nihar R Desai
BACKGROUND: Whereas heart failure (HF) is a complex clinical syndrome, conventional approaches to its management have treated it as a singular disease, leading to inadequate patient care and inefficient clinical trials. We hypothesized that applying advanced analytics to a large cohort of HF patients would improve prognostication of outcomes, identify distinct patient phenotypes, and detect heterogeneity in treatment response. METHODS AND RESULTS: The Swedish Heart Failure Registry is a nationwide registry collecting detailed demographic, clinical, laboratory, and medication data and linked to databases with outcome information...
April 12, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29650544/evaluation-and-management-of-right-sided-heart-failure-a-scientific-statement-from-the-american-heart-association
#19
REVIEW
Marvin A Konstam, Michael S Kiernan, Daniel Bernstein, Biykem Bozkurt, Miriam Jacob, Navin K Kapur, Robb D Kociol, Eldrin F Lewis, Mandeep R Mehra, Francis D Pagani, Amish N Raval, Carey Ward
BACKGROUND AND PURPOSE: The diverse causes of right-sided heart failure (RHF) include, among others, primary cardiomyopathies with right ventricular (RV) involvement, RV ischemia and infarction, volume loading caused by cardiac lesions associated with congenital heart disease and valvular pathologies, and pressure loading resulting from pulmonic stenosis or pulmonary hypertension from a variety of causes, including left-sided heart disease. Progressive RV dysfunction in these disease states is associated with increased morbidity and mortality...
April 12, 2018: Circulation
https://www.readbyqxmd.com/read/29650354/risk-factors-for-postoperative-delirium-in-patients-undergoing-free-flap-reconstruction-for-oral-cancer
#20
T Makiguchi, S Yokoo, J Kurihara
The aim of this study was to investigate risk factors for postoperative delirium in patients undergoing free flap reconstruction for defects after oral cancer resection. This was a non-randomized, retrospective cohort study involving 102 patients who underwent oral cancer resection and free flap reconstruction. Data were collected from the medical records. Postoperative delirium occurred in 34 patients (33.3%), of whom 27 were male and seven were female. High preoperative total protein and albumin, diabetes mellitus, history of smoking, use of hypnotics or antipsychotics, time until getting out of bed after surgery, and postoperative insomnia were significantly related to delirium in the univariate analysis (P<0...
April 10, 2018: International Journal of Oral and Maxillofacial Surgery
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