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https://www.readbyqxmd.com/read/29908296/sonographically-guided-plantaris-tendon-release-a-cadaveric-validation-study
#1
Jay Smith, Håkan Alfredson, Lorenzo Masci, Jacob L Sellon, Charonn D Woods
BACKGROUND: The plantaris tendon (PT) has been implicated in the pathogenesis of symptoms in a subset of patients with Achilles region pain syndromes and has been traditionally managed via open surgical resection. Although the PT can be visualized on ultrasound, a minimally invasive technique for sonographically guided PT release has not been formally described. OBJECTIVE: To validate a technique to perform sonographically guided PT release in an unembalmed cadaveric model...
June 13, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29901295/-results-of-a-comparative-multi-center-randomized-clinical-study-of-efficacy-and-safety-of-effex-tribulus-and-tribestan-in-patients-with-erectile-dysfunction
#2
L G Spivak, D V Platonova, D V Enikeev, L M Rapoport, A Z Vinarov, Yu L Demidko
RELEVANCE: Erectile dysfunction (ED) is a common condition. Pharmacological management of ED involves medications produced by chemical synthesis. Despite high efficiency, their use is often accompanied by some side effects. Considering this, herbal preparations with sufficient efficacy and greater safety have received much attention. AIM: To compare the efficacy and safety of two herbal preparations (EFFEX Tribulus and Tribestan) based on Tribulus Terrestris herb dry extract in patients with ED...
May 2018: Urologii︠a︡
https://www.readbyqxmd.com/read/29896465/start-a-neonatal-extracorporeal-membrane-oxygenation-program-a-multistep-team-training
#3
Genny Raffaeli, Stefano Ghirardello, Mara Vanzati, Chiara Baracetti, Francesco Canesi, Federica Conigliaro, Valerio Gentilino, Francesco Macchini, Monica Fumagalli, Fabrizio Ciralli, Nicola Pesenti, Sofia Passera, Simona Neri, Stefania Franzini, Ernesto Leva, Laura Plevani, Fabio Mosca, Giacomo Cavallaro
Background: Extracorporeal membrane oxygenation (ECMO) is a complex life-saving support for acute cardio-respiratory failure, unresponsive to medical treatment. Emergency events on ECMO are rare but require immediate and proficient management. Multidisciplinary ECMO team members need to acquire and maintain over time cognitive, technical and behavioral skills, to safely face life-threatening clinical scenarios. Methods: A multistep educational program was delivered in a 4-year period to 32 ECMO team members, based on guidelines from the Extracorporeal Life Support Organization...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29895324/toxocariasis-a-silent-threat-with-a-progressive-public-health-impact
#4
REVIEW
Jia Chen, Quan Liu, Guo-Hua Liu, Wen-Bin Zheng, Sung-Jong Hong, Hiromu Sugiyama, Xing-Quan Zhu, Hany M Elsheikha
BACKGROUND: Toxocariasis is a neglected parasitic zoonosis that afflicts millions of the pediatric and adolescent populations worldwide, especially in impoverished communities. This disease is caused by infection with the larvae of Toxocara canis and T. cati, the most ubiquitous intestinal nematode parasite in dogs and cats, respectively. In this article, recent advances in the epidemiology, clinical presentation, diagnosis and pharmacotherapies that have been used in the treatment of toxocariasis are reviewed...
June 13, 2018: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29890946/non-recovery-from-dialysis-requiring-acute-kidney-injury-and-short-term-mortality-and-cardiovascular-risk-a-cohort-study
#5
Benjamin J Lee, Chi-Yuan Hsu, Rishi V Parikh, Thomas K Leong, Thida C Tan, Sophia Walia, Kathleen D Liu, Raymond K Hsu, Alan S Go
BACKGROUND: The high mortality and cardiovascular disease (CVD) burden in patients with end-stage renal disease (ESRD) is well-documented. Recent literature suggests that acute kidney injury is also associated with CVD. It is unknown whether patients with incident ESRD due to dialysis-requiring acute kidney injury (AKI-D) are at higher short-term risk for death and CVD events, compared with incident ESRD patients without preceding AKI-D. Few studies have examined the impact of recovery from AKI-D on subsequent CVD risk...
June 11, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29889235/contemporary-medical-management-of-acute-severe-ulcerative-colitis
#6
Kaitlin G Whaley, Michael J Rosen
Acute severe ulcerative colitis is a medical emergency that requires prompt recognition, evaluation, and intervention. Patients require hospital admission with laboratory, radiographic, and endoscopic evaluation with initiation of corticosteroid treatment. Despite early intervention, many patients require salvage medical therapy, with some progressing to colectomy. Here we review important concepts and recent advances in the evaluation and medical management of adult and pediatric patients with acute severe ulcerative colitis...
June 7, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29888041/evaluating-generalizability-of-a-biospecimen-informatics-approach-support-for-local-requirements-and-best-practices
#7
Cindy Chen, Regina T Wulff, Evan T Sholle, Gail J Roboz, David A Kraemer, Thomas R Campion
To enable clinical and translational research, academic medical centers increasingly implement biospecimen information management systems. At our institution, one laboratory successfully implemented a multi-system solution that enabled collection and reporting of specimen- and aliquot-level data. The objective of this study was to assess the solution against the laboratory's requirements and with respect to support of best practices for biospecimen information management systems defined by the International Society for Biological and Environmental Repositories (ISBER)...
2018: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/29887581/utility-of-arterial-blood-gas-cbc-biochemistry-and-cardiac-hormones-as-evaluation-parameters-of-cardiovascular-disease-in-nonhuman-primates
#8
Shunya Nakayama, Hiroshi Koie, Kiichi Kanayama, Yuko Katakai, Yasuyo Ito-Fujishiro, Tadashi Sankai, Yasuhiro Yasutomi, Naohide Ageyama
Cardiovascular disease (CVD) has a tremendous impact on the quality of life of humans. While experimental animals are valuable to medical research as models of human diseases, cardiac systems differ widely across various animal species. Thus, we examined a CVD model in cynomolgus monkeys. Laboratory primates are precious resources, making it imperative that symptoms of diseases and disorders are detected as early as possible. Thus, in this study we comprehensively examined important indicators of CVD in cynomolgus monkeys, including arterial blood gas, complete blood count (CBC), biochemistry, and cardiac hormones...
June 11, 2018: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/29887235/laboratory-testing-in-primary-care-a-systematic-review-of-health-it-impacts
#9
REVIEW
Éric Maillet, Guy Paré, Leanne M Currie, Louis Raymond, Ana Ortiz de Guinea, Marie-Claude Trudel, Josianne Marsan
INTRODUCTION: Laboratory testing in primary care is a fundamental process that supports patient management and care. Any breakdown in the process may alter clinical information gathering and decision-making activities and can lead to medical errors and potential adverse outcomes for patients. Various information technologies are being used in primary care with the goal to support the process, maximize patient benefits and reduce medical errors. However, the overall impact of health information technologies on laboratory testing processes has not been evaluated...
August 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29886607/-relationship-between-phenotype-and-genotype-of-abcb11-deficiency-in-siblings-and-literature-review
#10
X R Peng, Y Lu, M H Zhang, L T Li, X B Xie, J Y Gong, J S Wang
Objective: To explore the relationship between genotype and phenotype of ABCB11 deficiency. Methods: Clinical data of two siblings with ABCB11 deficiency were retrospectively analyzed. Related literature from PubMed, CNKI and Wangfang databases was reviewed to date (up to August 2017) with 'ABCB11 gene' or 'bile salt export pump', 'cholestasis' and 'child' as key words. Results: The patients were siblings. Both of them presented as jaundice, pruritus and hepatosplenomegaly since 3 days after birth. Significant laboratory findings on admission of the older sister included high total bilirubin, 170 µmol/L;conjugated bilirubin, 115...
June 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29880106/incidence-and-outcomes-of-positive-bubble-contrast-study-results-after-transcatheter-closure-of-a-patent-foramen-ovale
#11
Ashish H Shah, Mark Osten, Lee Benson, Sami Alnasser, Yvonne Bach, Rohan Vishwanath, Alex Van De Bruaene, Healey Shulman, Jeneka Navaranjan, Rafique Khan, Eric Horlick
OBJECTIVES: The aim of this study was to assess the incidence of persistently positive results on agitated saline contrast injection after patent foramen ovale (PFO) closure, the underlying mechanism, and management. BACKGROUND: Transcatheter intervention to close a PFO is reasonable in highly selected patients younger than 60 years, after a thorough cardioneurological investigation following a cryptogenic stroke, particularly in the presence of thromboembolic disease or in patients at high risk for venous thrombosis...
June 11, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29879862/the-role-of-liver-transplantation-in-alcoholic-hepatitis
#12
Michelle Ma, Katie Falloon, Po-Hung Chen, Behnam Saberi, Aliaksei Pustavoitau, Elif Ozdogan, Zhiping Li, Benjamin Philosophe, Andrew M Cameron, Ahmet Gurakar
Acute alcoholic hepatitis is a syndrome of jaundice and hepatic decompensation that occurs with excessive alcohol consumption. The diagnosis can be made with a combination of clinical characteristics and laboratory studies, though biopsy may be required in unclear cases. Acute alcoholic hepatitis can range from mild to severe disease, as determined by a Maddrey discriminant function ≥32. Mild forms can be managed with supportive care and abstinence from alcohol. While mild form has an overall good prognosis, severe alcoholic hepatitis is associated with an extremely high short-term mortality of up to 50%...
January 1, 2018: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29879159/investigation-of-laboratory-confirmed-dengue-outbreak-in-north-eastern-kenya-2011
#13
Mark Obonyo, Ahmed Fidhow, Victor Ofula
The first laboratory confirmed dengue outbreak in Kenya was reported in coastal towns of Malindi and Kilifi in 1982. Since then, no other outbreak had been confirmed in Kenya. Dengue outbreak was confirmed among African Mission soldiers in Somalia (AMISOM) between May to October 2011. From September 2011, an upsurge of febrile patients who were negative for malaria on microscopy were reported in several health facilities in Mandera town, an adjacent area to Somalia in northern Kenya. We investigated a suspected dengue outbreak in Mandera town from 26th September 2011 to 5th October 2011...
2018: PloS One
https://www.readbyqxmd.com/read/29879029/no-obvious-sympathetic-excitation-after-massive-levothyroxine-overdose-a-case-report
#14
Jianxin Xue, Lei Zhang, Zhiqiang Qin, Ran Li, Yi Wang, Kai Zhu, Xiao Li, Xian Gao, Jianzhong Zhang
RATIONALE: Thyrotoxicosis from an overdose of medicinal thyroid hormone is a condition that may be associated with a significant delay in onset of toxicity. However, limited literature is available regarding thyrotoxicosis attributed to excessive ingestion of exogenous thyroid hormone and most cases described were pediatric clinical researches. Herein, we presented the course of a patient who ingested a massive amount of levothyroxine with no obvious sympathetic excited symptoms exhibited and reviewed feasible treatment options for such overdoses...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29876510/antegrade-pancreatoscopy-via-eus-guided-pancreaticogastrostomy-allows-removal-of-obstructive-pancreatic-duct-stones
#15
Theodore W James, Todd H Baron
Background and study aims : Endoscopic retrograde cholangiopancreatography (ERCP) is an effective treatment for pancreaticolithiasis, including use of pancreatoscopy for intraductal electrohydraulic lithotripsy (IEHL). Pancreatoscopy is often limited by a small-caliber downstream pancreatic duct as well as an unstable pancreatoscope position within the pancreatic head. Endoscopic ultrasound-guided pancreaticogastrostomy (EUS-PG) has been developed as a method to relieve ductal obstruction when retrograde access fails...
June 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29867243/the-eastern-shore-collaborative-for-interprofessional-education-s-implementation-and-impact-over-five-years
#16
Hoai-An Truong, Michelle J Gorman, Meghan East, Dennis W Klima, Katherine A Hinderer, G Lawrence Hogue, Voncelia Brown, Robert L Joyner
Health care professionals working collaboratively on interprofessional teams are essential to optimize patient-centered care. Collaboration and teamwork can be best achieved if interprofessional education (IPE) starts early for health professions students. This commentary describes the formation, implementation, impact, and lessons learned from students' curricular and co-curricular activities and faculty collaboration over a five-year trajectory of the Eastern Shore Collaborative for Interprofessional Education (ESCIPE)...
May 2018: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/29864612/relationship-between-serum-lipid-concentrations-and-posttraumatic-stress-symptoms-in-the-bereaved-after-the-sewol-ferry-disaster-a-prospective-cohort-study
#17
Hyejin Tae, Hyu Jung Huh, Jihyun Hwang, Jeong-Ho Chae
The objective of this study was to investigate the relationship between serum lipid concentrations and PTSD symptoms in the bereaved after a traumatic familial loss. Eighteen months after the Sewol ferry disaster, 107 subjects who experienced traumatic losses as a result of the accident completed a mental and medical survey as well as laboratory tests for lipid profiles. At 30 months after the trauma, a total of 64 individuals completed a follow-up psychometric survey and biochemical measurements. We performed multiple linear regression analyses, examining the association between PTSD symptoms and lipid profiles...
May 16, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29862103/severe-maternal-morbidity-associated-with-systemic-lupus-erythematosus-flare-in-the-second-trimester-of-pregnancy
#18
Matthew J Blitz, Adiel Fleischer
Pregnancy in women with systemic lupus erythematosus (SLE) is associated with an increased risk of adverse maternal and fetal outcomes. Here, we present a case of severe maternal morbidity in a 23-year-old primigravida with SLE and secondary Sjögren's syndrome who experienced a life-threatening multisystem flare at 17 weeks of gestational age. She presented to the emergency department complaining of cough with hemoptysis and shortness of breath. She developed hypoxic respiratory failure and was admitted to the intensive care unit...
2018: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29862101/-histoplasma-peritonitis-an-extremely-rare-complication-of-peritoneal-dialysis
#19
Asjad Sardar, Bijin Thajudeen, Pradeep V Kadambi
Bacterial peritonitis is a common complication of peritoneal dialysis, but fungal peritonitis is unusual and is mostly due to Candida species. Peritonitis due to Histoplasma capsulatum is rare and we report one such case. A 63-year-old female presented with progressively worsening abdominal pain, fever, and altered mental status. She had end-stage renal disease and had been on peritoneal dialysis for 4 years. She had abdominal tenderness without rebound or guarding. Laboratory studies and CT of abdomen were significant for leukocytosis and peritoneal membrane thickening, respectively...
2018: Case Reports in Nephrology
https://www.readbyqxmd.com/read/29861377/hypoglycemia-as-a-complication-of-intravenous-insulin-to-treat-hyperkalemia-in-the-emergency-department
#20
Nathaniel L Scott, Lauren R Klein, Ellen Cales, Brian E Driver
INTRODUCTION: Complications associated with the emergency department (ED) management of hyperkalemia are not well characterized. The goals of this study were to describe the frequency of hypoglycemia following the use of insulin to shift potassium intracellularly and to examine the association of key variables with this complication. METHODS: Adult ED patients (≥18 years old) with hyperkalemia (>5.3 mmol/L) were identified in the electronic medical record over a 5-year period at the study site...
May 10, 2018: American Journal of Emergency Medicine
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