keyword
https://read.qxmd.com/read/38497862/preoperative-bmi-and-hb-levels-are-important-predictors-of-massive-bleeding-in-liver-transplant-patients
#1
JOURNAL ARTICLE
K-D Chen, W Chen, B Hu, Z-S Zhao
OBJECTIVE: This study aims to compare intraoperative bleeding during liver transplant procedures and analyze the predictive role of preoperative laboratory indicators in significant intraoperative bleeding. PATIENTS AND METHODS: A retrospective analysis was conducted on 271 cases of allogeneic liver transplant patients from January 2018 to June 2023. Patients were categorized into the massive bleeding (MB) group and the non-massive bleeding (non-MB) group based on the occurrence of significant intraoperative bleeding...
March 2024: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38496192/the-value-of-electroencephalogram-eeg-findings-in-the-evaluation-and-treatment-management-of-pediatric-acute-liver-failure
#2
JOURNAL ARTICLE
Bilge Özgör, Sukru Gungor, Merve Aladağ, Fatma I Varol, Mahmut Aslan, Sezai Yilmaz, Serdal Gungor
Background Pediatric acute liver failure (PALF) is still life-threatening and requires urgent care. The presence of encephalopathy is a clinical diagnosis, but it is more difficult to diagnose in children than in adults, and an electroencephalogram (EEG) can be invaluable. The role of EEG in managing the treatment of patients with PALF, other than the identification of encephalopathy, is unknown. This study aimed to investigate patients' EEGs, which may guide in choosing the most appropriate treatment in encephalopathy children...
February 2024: Curēus
https://read.qxmd.com/read/38496028/six-sigma-evaluation-of-17-biochemistry-parameters-using-bias-calculated-from-internal-quality-control-and-external-quality-assurance-data
#3
JOURNAL ARTICLE
Tülay Çevlik, Goncagül Haklar
BACKGROUND: Six Sigma is a popular quality management system that enables continuous monitoring and improvement of analytical performance in the clinical laboratory. We aimed to calculate sigma metrics and quality goal index (QGI) for 17 biochemical analytes and compare the use of bias from internal quality control (IQC) and external quality assurance (EQA) data in the calculation of sigma metrics. METHODS: This retrospective study was conducted in Marmara University Pendik E&R Hospital Biochemistry Laboratory...
January 25, 2024: Journal of Medical Biochemistry
https://read.qxmd.com/read/38496022/artificial-intelligence-in-the-pre-analytical-phase-state-of-the-art-and-future-perspectives
#4
JOURNAL ARTICLE
Giuseppe Lippi, Camilla Mattiuzzi, Emmanuel J Favaloro
The use of artificial intelligence (AI) has become widespread in many areas of science and medicine, including laboratory medicine. Although it seems obvious that the analytical and post-analytical phases could be the most important fields of application in laboratory medicine, a kaleidoscope of new opportunities has emerged to extend the benefits of AI to many manual labor-intensive activities belonging to the pre-analytical phase, which are inherently characterized by enhanced vulnerability and higher risk of errors...
January 25, 2024: Journal of Medical Biochemistry
https://read.qxmd.com/read/38495864/biomedical-laboratory-scientists-and-technicians-in-digital-pathology-is-there-a-need-for-professional-development
#5
JOURNAL ARTICLE
Charlotte Lerbech Jensen, Lisbeth Koch Thomsen, Mette Zeuthen, Sys Johnsen, Rima El Jashi, Michael Friberg Bruun Nielsen, Line E Hemstra, Julie Smith
OBJECTIVE: Digital pathology (DP) is moving into Danish pathology departments at high pace. Conventionally, biomedical laboratory scientists (BLS) and technicians have prepared tissue sections for light microscopy, but workflow alterations are required for the new digital era with whole slide imaging (WSI); digitally assisted image analysis (DAIA) and artificial intelligence (AI). We aim to explore the role of BLS in DP and assess a potential need for professional development. METHODS: We investigated the roles of BLS in the new digital era through qualitative interviews at Danish Pathology Departments in 2019/2020 before DP implementation (supported by a questionnaire); and in 2022 after DP implementation...
2024: Digital Health
https://read.qxmd.com/read/38495831/urothelial-carcinoma-masquerading-as-retroperitoneal-fibrosis-a-case-report
#6
David Luengo, Ángela Salmerón, Antonio Medina, Javier Pastor, Mercedes Caba
Retroperitoneal fibrosis, a rare and often idiopathic condition, poses significant diagnostic challenges. While most cases are considered idiopathic or immune-mediated, a small but important proportion are associated with malignant neoplasms, with implications for prognosis and management. The present study describes the case of a 69-year-old man who presented to the emergency department of the Virgen de las Nieves University Hospital (Granada, Spain), with a 2-week history of epigastric pain, vomiting and altered bowel habits...
May 2024: Oncology Letters
https://read.qxmd.com/read/38495477/unmasking-the-enigma-influenza-vaccine-and-the-rare-case-of-post-vaccination-pericarditis
#7
Ekrem Yetiskul, Alaukika Agarwal, Gaetano Di Pietro, Faris Qaqish, Salman Khan, Shahkar Khan
Acute pericarditis is an inflammatory condition involving the pericardium, the double-layered sac that surrounds the heart. It is characterized by chest pain, typically pleuritic and sharp, along with other clinical and laboratory findings indicative of pericardial inflammation. While acute pericarditis following influenza vaccination is rare, it has been reported in medical literature. The relationship between vaccinations, including the influenza vaccine, and pericarditis is particularly interesting, as it has implications for public health and vaccination programs...
2024: Case Reports in Infectious Diseases
https://read.qxmd.com/read/38494381/asynchronous-consult-report-generation-for-pharmacogenomic-clinical-support-time-and-motion
#8
JOURNAL ARTICLE
David R Bright, Donald Klepser, Anna Langerveld
As pharmacogenomic (PGx) testing becomes more commonplace in clinical practice, appropriate application of laboratory data to all relevant medications becomes necessary to maximize PGx value. However, many clinicians lack PGx knowledge and confidence, so prescribers may appreciate clinical support when applying PGx data to a patient's entire medication list. Pharmacists routinely provide PGx consult support, and asynchronous written consults may improve logistical simplicity, but specific process steps and time expectations are less settled...
March 8, 2024: Research in Social & Administrative Pharmacy: RSAP
https://read.qxmd.com/read/38492023/association-between-intuitive-eating-and-health-outcomes-in-outpatients-with-type-2-diabetes-a-cross-sectional-study
#9
JOURNAL ARTICLE
Olívia Garbin Koller, Vanessa Machado Menezes, Aline Busanello, Jussara Carnevale de Almeida
PURPOSE: To evaluate the association between intuitive eating and health outcomes in patients with type 2 diabetes in a cross-sectional study. METHODS: Consecutively, outpatients attending at university hospital underwent clinical, laboratory, lifestyle, and eating behavior evaluations. Intuitive eating was assessed using the Intuitive Eating Scale-2 (IES-2), and the Three Factor Eating Questionnaire-21 was adopted as a confirmatory tool for disordered eating behavior...
March 16, 2024: European Journal of Nutrition
https://read.qxmd.com/read/38491367/clinical-presentation-and-management-of-multisystem-inflammatory-syndrome-in-children-associated-with-covid-19-a-retrospective-observational-descriptive-study-in-a-pediatric-hospital-in-syria
#10
JOURNAL ARTICLE
Eman Shhada, Hussein Hamdar, Ali Alakbar Nahle, Diana Mourad, Basheer Khalil, Sawssan Ali
OBJECTIVE: Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19 is a rare and serious medical condition. This study aims to review the clinical presentation, laboratory parameters, outcomes, and management of MIS-C cases in a pediatric hospital in Syria. METHODS: This retrospective observational study aimed to investigate MIS-C between May 2020 and October 2021. Data collection involved extracting information from medical records, and patients were identified based on the case definition established by the World Health Organization (WHO)...
March 15, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38489683/exploring-the-intersection-peptic-ulcers-and-hemolysis-unraveling-the-complex-relationship
#11
JOURNAL ARTICLE
Emmanuel Ifeanyi Obeagu, Getrude Uzoma Obeagu
This paper investigates the intriguing relationship between peptic ulcers and hemolysis, 2 seemingly distinct medical conditions, aiming to unravel their potential interconnections and clinical implications. While traditionally studied in isolation, recent evidence has surfaced suggesting possible links and shared mechanisms between these conditions. This paper explores the underlying pathophysiological associations, shared risk factors, diagnostic challenges, management strategies, and implications for clinical practice and health policy...
March 15, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38489122/strategic-behaviour-and-decision-making-in-competitive-hospital-markets-an-experimental-investigation
#12
JOURNAL ARTICLE
Johann Han, Nadja Kairies-Schwarz, Markus Vomhof
We investigate quality provision and the occurrence of strategic behaviour in competitive hospital markets where providers are assumed to be semi-altruistic towards patients. For this, we employ a laboratory experiment with a hospital market framing. Subjects decide on the quality levels for one of three competing hospitals respectively. We vary the organizational aspect of whether quality decisions within hospitals are made by individuals or teams. Realized monetary patient benefits go to real patients outside the lab...
March 15, 2024: International Journal of Health Economics and Management
https://read.qxmd.com/read/38487125/a-case-report-unveiling-the-underlying-cause-of-recurrent-pericarditis-in-a-patient-with-undifferentiated-connective-tissue-disease
#13
Samantha Boever, Kareem Bannis
Undifferentiated connective tissue disease (UCTD) is a condition characterized by symptoms and laboratory findings related to various systematic autoimmune diseases. Severe symptoms like chest pain in patients with UCTD could suggest an underlying secondary condition, such as pericarditis. Our case involves a 36-year-old woman with a history of UCTD and recently diagnosed rheumatoid arthritis (RA) who presented with persistent sub-sternal chest pain and pressure that began three weeks ago. Over the past year, she experienced six similar episodes of chest pain, diagnosed as idiopathic pericarditis...
February 2024: Curēus
https://read.qxmd.com/read/38487063/awareness-of-hypertension-in-reproductive-aged-women-living-with-chronic-kidney-disease
#14
JOURNAL ARTICLE
Danica H Chang, Sofia B Ahmed, Victoria J Riehl-Tonn, Cindy Z Kalenga, Darlene Y Sola, Sandra M Dumanski
BACKGROUND: Hypertension is the most important modifiable cardiovascular risk factor among women. Chronic kidney disease (CKD), which affects 1 in 10 reproductive-aged women, increases the risk of hypertension; however, awareness of hypertension in this population is unknown. This study aimed to determine hypertension awareness among reproductive-aged women living with chronic kidney disease. METHODS: Women aged 18 to 50 years with CKD were recruited from nephrology clinics in Calgary, Alberta, Canada...
February 2024: CJC open
https://read.qxmd.com/read/38487027/prevalence-and-effect-on-prognosis-of-sarcopenia-in-patients-with-primary-biliary-cholangitis
#15
JOURNAL ARTICLE
Jiaqi Yang, Shuangshuang Jiang, Qingling Fan, Didi Wen, Yansheng Liu, Kemei Wang, Hui Yang, Changcun Guo, Xinmin Zhou, Guanya Guo, Yulong Shang, Ying Han
BACKGROUND: Sarcopenia adversely affects the treatment outcomes in Cirrhosis and NAFLD. However, such research is limited in primary biliary cholangitis (PBC) patients. This study was performed to examine the prevalence of sarcopenia and its impact on PBC patients' prognoses. METHODS: This study enrolled confirmed PBC patients who had an abdominal CT scan. Sarcopenia was determined by the L3-skeletal muscle index with a Chinese population-based cut-off value. Laboratory test values and liver stiffness measurements values were obtained from the electronic medical records...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38486373/accuracy-of-mri-based-radiomics-in-diagnosis-of-placenta-accreta-spectrum-a-prisma-systematic-review-and-meta-analysis
#16
JOURNAL ARTICLE
Liqiong Huang, Lin Ma, Qin Zhou, Yi Hu, Lirong Hu, Yang Luo, Yan Li
BACKGROUND Placenta accreta syndrome (PAS) can lead to severe obstetric bleeding, and can be life-threatening. This study aimed to assess the precision of radiomics features derived from magnetic resonance imaging (MRI) for diagnosing PAS. MATERIAL AND METHODS A comprehensive search was conducted in the databases PubMed, Embase, Web of Science, and the Cochrane library from inception to October 2023. We included diagnostic accuracy studies utilizing radiomics-MRI in PAS patients, with histopathology serving as the reference standard...
March 15, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38484713/diagnostic-methods-for-helicobacter-pylori
#17
REVIEW
Liana Cristina Melo Carneiro Costa, Maria das Graças Carvalho, Ana Cristina La Guárdia Custódio Pereira, Rafael Gonçalves Teixeira Neto, Lívia Carolina Andrade Figueiredo, Melina Barros-Pinheiro
H. pylori infection is a significant global health concern. It cannot be diagnosed based solely on the patient's medical history and symptoms, and laboratory and imaging tests are often required to confirm the diagnosis. Both non-invasive and invasive methods are available for diagnosing H. pylori infection, including conventional and advanced detection techniques. It is not uncommon for patients to present with false-negative results due to the use of inadequate investigation methodologies, which prevents the adoption of appropriate clinical management...
March 14, 2024: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/38482624/advances-in-the-treatment-of-kidney-disorders-using-mesenchymal-stem-cells
#18
JOURNAL ARTICLE
Shivam Rajput, Rishabha Malviya, Prerna Uniyal
Renal disease is a medical condition that poses a potential threat to the life of an individual and is related to substantial morbidity and mortality rates in clinical environments. The aetiology of this condition is influenced by multiple factors, and its incidence tends to increase with progressive aging. Although supportive therapy and kidney transplantation have potential advantages, they also have limitations in terms of mitigating the progression of KD. Despite significant advancements in the domain of supportive therapy, mortality rates in patients continue to increase...
March 13, 2024: Current Pharmaceutical Design
https://read.qxmd.com/read/38482328/risk-factors-and-etiology-of-early-onset-neonatal-sepsis-in-northeastern-part-of-india-case-control-study
#19
JOURNAL ARTICLE
Sudesh Kumar, Piyali Bhattacharya, Simranjit Kaur, Prajna Ray, Nandita Chattopadhyay
BACKGROUND: Sepsis, the second most common cause of neonatal mortality, causes more than one million deaths annually. India has the highest incidence of clinical sepsis (17000/100000 live birth). OBJECTIVE: This study aimed to determine the risk factors and organisms of early-onset neonatal sepsis (EONS) in a tertiary care hospital in Northeast India. MATERIALS AND METHODS: It was a case-control study conducted in the neonatal unit of MGM Medical College, Kishanganj, Bihar, from January 2022 to April 2023...
January 2024: Journal of Family Medicine and Primary Care
https://read.qxmd.com/read/38481932/identified-pah-v230a-and-pah-v230i-mutations-in-a-family-with-diverse-clinical-presentations
#20
Faeze Khaghani, Peyman Eshraghi, Tayebeh Hamzehloei
Phenylketonuria (PKU) is a hereditary disorder caused by phenylalanine hydroxylase enzyme (PAH) defects that might cause severe brain damage. The current main treatment, dietary management, can prevent the symptoms if commenced early. However, it has side effects if used for a long time. Additionally, some patients with mild hyperphenylalaninemia (mHPA), who has serum phenylalanine levels <360 μmol/L, do not require treatment. Since the correlation between genotype and metabolic phenotype has been demonstrated earlier, genotype-based detection of patients who do not need treatment might help with genetic counseling and choosing the most appropriate treatment option...
March 2024: Clinical Case Reports
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